Humanigen, Inc., a clinical stage biopharmaceutical company, develops a portfolio of anti-inflammatory immunology and immuno-oncology monoclonal antibodies in the United States. The company's lead product candidate is Lenzilumab, a monoclonal antibody that targets and neutralizes human granulocyte-macrophage colony-stimulating factor, which has completed Phase III clinical trial for the treatment of cytokine storm associated with COVID-19; and Phase Ib/II clinical trial as a sequenced therapy in combination with CD19 targeted chimeric antigen receptor T-cell therapies to treat patients with relapsed or refractory B-cell lymphoma, as well as that is in Phase II clinical trial in patients with chronic myelomonocytic leukemia. It also develops Ifabotuzumab, a humaneered monoclonal antibody that targets EphA3 receptor, which has completed the Phase I dose escalation portion of a Phase I/II clinical trial in multiple hematologic malignancies; and HGEN005, an anti-EMR1 monoclonal antibody, which has completed pre-clinical stage for the treatment of eosinophilic disorders. Humanigen, Inc. has a clinical collaboration agreement with Kite Pharma, Inc. to conduct a multi-center Phase Ib/II study of Lenzilumab in patients with relapsed or refractory diffuse large B-cell lymphoma; and a cooperative research and development agreement with the Department of Defense to assist in the development of lenzilumab in advance of a potential emergency use authorization for COVID-19. The company was formerly known as KaloBios Pharmaceuticals, Inc. and changed its name to Humanigen, Inc. in August 2017. Humanigen, Inc. was incorporated in 2000 and is headquartered in Short Hills, New Jersey. |
Insider Trading |
Relationship |
Date |
Transaction |
Cost |
#Shares |
Value ($) |
#Shares Total |
SEC Form 4 |
Chappell Dale | Chief Scientific Officer | Mar 11 | Buy | 3.00 | 1,000,000 | 3,000,000 | 7,944,985 | Mar 15 06:23 PM | Kilcoyne Adrian | Chief Medical Officer | Mar 09 | Buy | 2.78 | 5,000 | 13,900 | 12,000 | Mar 14 04:37 PM | Kilcoyne Adrian | Chief Medical Officer | Mar 08 | Buy | 2.53 | 7,000 | 17,710 | 7,000 | Mar 14 04:37 PM | Durrant Cameron | Chief Executive Officer | Mar 02 | Buy | 2.34 | 40,000 | 93,600 | 70,000 | Mar 04 06:06 AM | Jordan Edward P. | Chief Commercial Officer | Mar 02 | Buy | 2.32 | 12,500 | 29,000 | 12,500 | Mar 04 06:05 AM | Chappell Dale | Chief Scientific Officer | Aug 12 | Sale | 17.16 | 57,551 | 987,564 | 873,693 | Aug 13 09:28 PM | Chappell Dale | Chief Scientific Officer | Aug 11 | Sale | 17.07 | 109,647 | 1,872,146 | 878,009 | Aug 13 09:28 PM | Chappell Dale | Chief Scientific Officer | Jul 29 | Sale | 17.03 | 29,394 | 500,703 | 884,029 | Jul 30 09:01 PM | Chappell Dale | Chief Scientific Officer | Jul 28 | Sale | 17.04 | 9,692 | 165,162 | 886,233 | Jul 30 09:01 PM | Chappell Dale | Chief Scientific Officer | Jul 23 | Sale | 17.04 | 5,584 | 95,155 | 886,960 | Jul 23 08:32 PM | Chappell Dale | Chief Scientific Officer | Jul 22 | Sale | 17.04 | 178,005 | 3,032,796 | 887,379 | Jul 23 08:32 PM | Chappell Dale | Chief Scientific Officer | Jul 21 | Sale | 17.14 | 132,764 | 2,275,124 | 900,729 | Jul 23 08:32 PM | Chappell Dale | Chief Scientific Officer | Jul 14 | Sale | 17.06 | 15,177 | 258,847 | 910,686 | Jul 16 08:28 PM | Chappell Dale | Chief Scientific Officer | Jul 09 | Sale | 17.37 | 296,036 | 5,142,767 | 911,824 | Jul 09 09:01 PM | Chappell Dale | Chief Scientific Officer | Jul 08 | Sale | 17.17 | 48,010 | 824,111 | 934,027 | Jul 09 09:01 PM | Chappell Dale | Chief Scientific Officer | Jun 25 | Sale | 17.80 | 1,000,000 | 17,803,500 | 972,361 | Jun 25 09:01 PM | Chappell Dale | Chief Scientific Officer | Jun 24 | Sale | 18.37 | 139,529 | 2,563,831 | 1,047,361 | Jun 25 09:01 PM | Chappell Dale | Chief Scientific Officer | Jun 23 | Sale | 18.28 | 133,126 | 2,434,182 | 1,057,826 | Jun 25 09:01 PM | Chappell Dale | Chief Scientific Officer | Jun 18 | Sale | 18.50 | 402,480 | 7,445,558 | 1,067,811 | Jun 21 08:57 PM | Chappell Dale | Chief Scientific Officer | Jun 17 | Sale | 19.17 | 181,423 | 3,478,441 | 1,097,997 | Jun 21 08:57 PM | Chappell Dale | Chief Scientific Officer | Jun 16 | Sale | 19.41 | 158,486 | 3,076,187 | 1,111,604 | Jun 21 08:57 PM | Durrant Cameron | Chief Executive Officer | Jun 14 | Sale | 20.64 | 81,441 | 1,680,934 | 30,000 | Jun 16 09:40 PM | Jordan Edward P. | Chief Commercial Officer | Jun 08 | Option Exercise | 9.65 | 14,700 | 141,855 | 14,700 | Jun 09 05:10 PM | Jordan Edward P. | Chief Commercial Officer | Jun 08 | Sale | 20.08 | 14,700 | 295,176 | 0 | Jun 09 05:10 PM | Chappell Dale | Chief Scientific Officer | Jun 07 | Sale | 19.08 | 80,636 | 1,538,793 | 1,124,334 | Jun 09 04:45 PM | Chappell Dale | Chief Scientific Officer | Jun 04 | Sale | 18.46 | 127,084 | 2,346,415 | 1,137,066 | Jun 04 06:07 PM | Chappell Dale | Chief Scientific Officer | Jun 03 | Sale | 18.37 | 191,154 | 3,511,308 | 1,157,132 | Jun 04 06:07 PM | Chappell Dale | Chief Scientific Officer | Jun 02 | Sale | 19.01 | 76,126 | 1,447,269 | 1,187,314 | Jun 04 06:07 PM |
|