Insider Trading |
Relationship |
Date |
Transaction |
Cost |
#Shares |
Value ($) |
#Shares Total |
SEC Form 4 |
Mates Sharon | Officer | Dec 04 '24 | Proposed Sale | 85.73 | 51,000 | 4,372,478 | | Dec 04 04:18 PM | Halstead Michael | President | Nov 13 '24 | Option Exercise | 36.89 | 18,714 | 690,359 | 18,714 | Nov 14 06:01 PM | Halstead Michael | President | Nov 12 '24 | Option Exercise | 23.94 | 22,869 | 547,484 | 22,869 | Nov 14 06:01 PM | Halstead Michael | President | Nov 12 '24 | Sale | 89.12 | 22,869 | 2,038,079 | 0 | Nov 14 06:01 PM | Halstead Michael | President | Nov 13 '24 | Sale | 88.38 | 18,714 | 1,654,021 | 0 | Nov 14 06:01 PM | Halstead Michael | Officer | Nov 12 '24 | Proposed Sale | 89.08 | 41,583 | 3,704,223 | | Nov 12 04:28 PM | ALEXANDRIA VENTURE INVESTMENTS | Director | Sep 06 '24 | Proposed Sale | 73.17 | 25,000 | 1,829,178 | | Sep 06 05:43 PM | Mates Sharon | Chairman and CEO | Aug 29 '24 | Option Exercise | 12.73 | 35,604 | 453,239 | 1,105,933 | Aug 30 06:01 PM | Mates Sharon | Chairman and CEO | Aug 30 '24 | Option Exercise | 12.73 | 34,396 | 437,861 | 1,104,725 | Aug 30 06:01 PM | Mates Sharon | Chairman and CEO | Aug 29 '24 | Sale | 72.57 | 35,604 | 2,583,884 | 1,070,329 | Aug 30 06:01 PM | Mates Sharon | Chairman and CEO | Aug 30 '24 | Sale | 72.84 | 34,396 | 2,505,351 | 1,070,329 | Aug 30 06:01 PM | Mates Sharon | Officer | Aug 30 '24 | Proposed Sale | 72.78 | 34,396 | 2,503,218 | | Aug 30 04:06 PM | Mates Sharon | Officer | Aug 29 '24 | Proposed Sale | 72.51 | 35,604 | 2,581,677 | | Aug 29 04:34 PM | Mates Sharon | Chairman and CEO | Aug 27 '24 | Option Exercise | 17.57 | 40,513 | 711,813 | 1,110,842 | Aug 28 06:00 PM | Mates Sharon | Chairman and CEO | Aug 28 '24 | Option Exercise | 17.57 | 32,699 | 574,521 | 1,103,028 | Aug 28 06:00 PM | Mates Sharon | Chairman and CEO | Aug 26 '24 | Option Exercise | 17.57 | 22,713 | 399,067 | 1,093,042 | Aug 28 06:00 PM | Mates Sharon | Chairman and CEO | Aug 27 '24 | Sale | 73.58 | 40,513 | 2,981,056 | 1,070,329 | Aug 28 06:00 PM | Mates Sharon | Chairman and CEO | Aug 28 '24 | Sale | 72.75 | 32,699 | 2,378,801 | 1,070,329 | Aug 28 06:00 PM | Mates Sharon | Chairman and CEO | Aug 26 '24 | Sale | 74.59 | 22,713 | 1,694,229 | 1,070,329 | Aug 28 06:00 PM | Mates Sharon | Officer | Aug 28 '24 | Proposed Sale | 72.69 | 32,699 | 2,376,774 | | Aug 28 04:34 PM | Mates Sharon | Officer | Aug 27 '24 | Proposed Sale | 73.52 | 40,513 | 2,978,542 | | Aug 27 04:22 PM | Mates Sharon | Officer | Aug 26 '24 | Proposed Sale | 74.53 | 22,713 | 1,692,819 | | Aug 26 04:36 PM | Mates Sharon | Chairman and CEO | Aug 21 '24 | Option Exercise | 17.57 | 53,013 | 931,438 | 1,123,342 | Aug 23 06:00 PM | Mates Sharon | Chairman and CEO | Aug 22 '24 | Option Exercise | 17.57 | 39,380 | 691,907 | 1,109,709 | Aug 23 06:00 PM | Mates Sharon | Chairman and CEO | Aug 23 '24 | Option Exercise | 17.57 | 28,680 | 503,908 | 1,099,009 | Aug 23 06:00 PM | Mates Sharon | Chairman and CEO | Aug 21 '24 | Sale | 75.65 | 53,013 | 4,010,501 | 1,070,329 | Aug 23 06:00 PM | Mates Sharon | Chairman and CEO | Aug 22 '24 | Sale | 74.68 | 39,380 | 2,940,802 | 1,070,329 | Aug 23 06:00 PM | Mates Sharon | Chairman and CEO | Aug 23 '24 | Sale | 74.46 | 28,680 | 2,135,435 | 1,070,329 | Aug 23 06:00 PM | Mates Sharon | Officer | Aug 23 '24 | Proposed Sale | 74.40 | 28,680 | 2,133,656 | | Aug 23 04:14 PM | Mates Sharon | Officer | Aug 22 '24 | Proposed Sale | 74.62 | 39,380 | 2,938,358 | | Aug 22 04:09 PM | Mates Sharon | Officer | Aug 21 '24 | Proposed Sale | 75.59 | 53,013 | 4,007,208 | | Aug 21 04:25 PM | Neumann Mark | EVP, Chief Commercial Officer | Aug 16 '24 | Option Exercise | 36.89 | 18,714 | 690,359 | 48,414 | Aug 20 06:03 PM | Neumann Mark | EVP, Chief Commercial Officer | Aug 16 '24 | Sale | 75.08 | 18,714 | 1,405,047 | 29,700 | Aug 20 06:03 PM | Neumann Mark | Officer | Aug 16 '24 | Proposed Sale | 75.02 | 18,714 | 1,403,972 | | Aug 16 04:04 PM | RIGGS RORY B | Director | Jun 24 '24 | Option Exercise | 16.86 | 20,000 | 337,200 | 121,062 | Jun 25 06:04 PM | RIGGS RORY B | Director | Jun 24 '24 | Sale | 75.57 | 4,462 | 337,193 | 116,600 | Jun 25 06:04 PM | VAN NOSTRAND ROBERT L | Director | Jun 18 '24 | Option Exercise | 16.86 | 20,000 | 337,200 | 29,690 | Jun 21 06:00 PM | VAN NOSTRAND ROBERT L | Director | Jun 18 '24 | Sale | 75.91 | 20,000 | 1,518,199 | 9,690 | Jun 21 06:00 PM | Mates Sharon | Chairman and CEO | Apr 24 '24 | Option Exercise | 17.26 | 20,020 | 345,618 | 1,070,329 | Apr 25 05:08 PM | RIGGS RORY B | Director | Mar 20 '24 | Option Exercise | 18.56 | 20,000 | 371,200 | 99,235 | Mar 22 04:12 PM | Mates Sharon | Chairman, President & CEO | Mar 07 '24 | Sale | 66.50 | 40,712 | 2,707,277 | 1,050,309 | Mar 11 08:33 PM | Mates Sharon | Chairman, President & CEO | Mar 11 '24 | Sale | 65.21 | 20,565 | 1,341,123 | 1,050,309 | Mar 11 08:33 PM | Hineline Lawrence J. | SVP of Finance, CFO | Mar 10 '24 | Option Exercise | 56.73 | 4,539 | 257,497 | 4,539 | Mar 11 08:33 PM | Hineline Lawrence J. | SVP of Finance, CFO | Mar 07 '24 | Sale | 66.60 | 13,132 | 874,560 | 0 | Mar 11 08:33 PM | Hineline Lawrence J. | SVP of Finance, CFO | Mar 11 '24 | Sale | 65.96 | 10,121 | 667,587 | 0 | Mar 11 08:33 PM | Halstead Michael | EVP and General Counsel | Mar 07 '24 | Sale | 66.15 | 13,132 | 868,698 | 0 | Mar 11 08:32 PM | Halstead Michael | EVP and General Counsel | Mar 11 '24 | Sale | 65.97 | 7,345 | 484,537 | 0 | Mar 11 08:32 PM | Neumann Mark | EVP, Chief Commercial Officer | Mar 07 '24 | Sale | 66.57 | 13,132 | 874,179 | 29,700 | Mar 11 08:31 PM | Neumann Mark | EVP, Chief Commercial Officer | Mar 11 '24 | Sale | 65.61 | 7,345 | 481,931 | 29,700 | Mar 11 08:31 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Mar 07 '24 | Sale | 66.56 | 6,450 | 429,308 | 16,170 | Mar 11 08:31 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Mar 11 '24 | Sale | 65.59 | 3,712 | 243,482 | 19,803 | Mar 11 08:31 PM | VAN NOSTRAND ROBERT L | Director | Feb 27 '24 | Option Exercise | 18.56 | 20,000 | 371,200 | 29,611 | Feb 28 07:41 PM | VAN NOSTRAND ROBERT L | Director | Feb 27 '24 | Sale | 72.93 | 20,000 | 1,458,650 | 9,611 | Feb 28 07:41 PM | Halstead Michael | EVP and General Counsel | Feb 26 '24 | Sale | 69.53 | 7,907 | 549,784 | 0 | Feb 27 08:00 PM | Hineline Lawrence J. | SVP of Finance, CFO | Feb 26 '24 | Option Exercise | 36.89 | 5,882 | 216,987 | 5,882 | Feb 27 08:00 PM | Hineline Lawrence J. | SVP of Finance, CFO | Feb 26 '24 | Sale | 69.43 | 13,337 | 925,961 | 0 | Feb 27 08:00 PM | Mates Sharon | Chairman, President & CEO | Feb 26 '24 | Sale | 69.79 | 22,590 | 1,576,464 | 1,050,309 | Feb 27 07:59 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Feb 26 '24 | Sale | 70.17 | 4,112 | 288,534 | 9,488 | Feb 27 07:58 PM | Neumann Mark | EVP, Chief Commercial Officer | Feb 26 '24 | Sale | 70.13 | 7,907 | 554,491 | 29,700 | Feb 27 07:58 PM | MARCUS JOEL S | Director | Feb 26 '24 | Option Exercise | 48.93 | 36,757 | 1,798,678 | 65,990 | Feb 27 07:57 PM | MARCUS JOEL S | Director | Feb 26 '24 | Sale | 68.68 | 26,328 | 1,808,253 | 39,662 | Feb 27 07:57 PM | Halstead Michael | EVP and General Counsel | Feb 02 '24 | Sale | 66.42 | 11,860 | 787,719 | 0 | Feb 05 06:13 PM | Mates Sharon | Chairman, President & CEO | Feb 02 '24 | Sale | 67.07 | 33,885 | 2,272,694 | 1,050,309 | Feb 05 06:10 PM | Neumann Mark | EVP, Chief Commercial Officer | Feb 02 '24 | Sale | 67.15 | 11,860 | 796,367 | 29,700 | Feb 05 06:07 PM | Hineline Lawrence J. | SVP of Finance, CFO | Feb 02 '24 | Sale | 66.62 | 11,183 | 745,037 | 0 | Feb 05 06:05 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Feb 02 '24 | Sale | 67.19 | 6,167 | 414,355 | 5,693 | Feb 05 06:02 PM | Mates Sharon | Chairman, President & CEO | Jan 16 '24 | Option Exercise | 16.86 | 75,361 | 1,270,586 | 1,125,670 | Jan 18 07:47 PM | Mates Sharon | Chairman, President & CEO | Jan 18 '24 | Option Exercise | 16.86 | 67,917 | 1,145,081 | 1,118,226 | Jan 18 07:47 PM | Mates Sharon | Chairman, President & CEO | Jan 17 '24 | Option Exercise | 16.86 | 48,084 | 810,696 | 1,098,393 | Jan 18 07:47 PM | Mates Sharon | Chairman, President & CEO | Jan 16 '24 | Sale | 67.25 | 75,361 | 5,067,982 | 1,050,309 | Jan 18 07:47 PM | Mates Sharon | Chairman, President & CEO | Jan 18 '24 | Sale | 65.19 | 67,917 | 4,427,848 | 1,050,309 | Jan 18 07:47 PM | Mates Sharon | Chairman, President & CEO | Jan 17 '24 | Sale | 66.24 | 48,084 | 3,185,062 | 1,050,309 | Jan 18 07:47 PM | Halstead Michael | EVP and General Counsel | Jan 11 '24 | Option Exercise | 13.60 | 50,000 | 680,051 | 50,000 | Jan 12 06:02 PM | Halstead Michael | EVP and General Counsel | Jan 11 '24 | Sale | 66.83 | 50,000 | 3,341,699 | 0 | Jan 12 06:02 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Jan 02 '24 | Option Exercise | 19.87 | 62,282 | 1,237,543 | 62,282 | Jan 04 07:54 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Jan 02 '24 | Sale | 70.60 | 62,282 | 4,397,113 | 0 | Jan 04 07:54 PM | Durgam Suresh K. | EVP, Chief Medical Officer | Dec 13 '23 | Sale | 65.00 | 21,262 | 1,382,030 | 0 | Dec 15 05:01 PM |
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