| Ticker |
Owner |
Relationship |
Date |
Transaction |
Cost  |
#Shares |
Value ($) |
#Shares Total |
SEC Form 4 |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 17 '26 | Sale | 0.35 | 416,911 | 145,919 | 303,719 | Jun 22 06:59 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 12 '26 | Sale | 0.40 | 170,441 | 68,176 | 349,907 | Jun 16 06:01 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 15 '26 | Sale | 0.39 | 128,770 | 50,220 | 341,353 | Jun 16 06:01 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 16 '26 | Sale | 0.37 | 149,625 | 55,361 | 331,414 | Jun 16 06:01 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 09 '26 | Sale | 0.37 | 369,800 | 136,826 | 381,717 | Jun 11 08:13 PM |
|
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 10 '26 | Sale | 0.37 | 45,923 | 16,992 | 378,666 | Jun 11 08:13 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 11 '26 | Sale | 0.38 | 262,503 | 99,751 | 361,229 | Jun 11 08:13 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 08 '26 | Sale | 0.71 | 376,526 | 267,333 | 418,813 | May 12 06:26 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 11 '26 | Sale | 0.67 | 87,490 | 58,618 | 413,001 | May 12 06:26 PM |
| HOWL | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 12 '26 | Sale | 0.64 | 101,151 | 64,737 | 406,282 | May 12 06:26 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 22 '26 | Sale | 15.77 | 165,150 | 2,604,416 | 2,402,095 | Apr 24 06:12 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 17 '26 | Sale | 16.28 | 458,411 | 7,462,931 | 2,739,208 | Apr 21 07:04 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 20 '26 | Sale | 15.77 | 171,963 | 2,711,857 | 2,567,245 | Apr 21 07:04 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 13 '26 | Sale | 16.15 | 530,610 | 8,569,352 | 3,404,998 | Apr 15 05:29 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 14 '26 | Sale | 15.97 | 153,735 | 2,455,148 | 3,251,263 | Apr 15 05:29 PM |
|
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 15 '26 | Sale | 16.01 | 53,644 | 858,840 | 3,197,619 | Apr 15 05:29 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 08 '26 | Sale | 16.48 | 484,104 | 7,977,786 | 4,071,637 | Apr 10 06:23 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 09 '26 | Sale | 16.59 | 135,201 | 2,242,985 | 3,936,436 | Apr 10 06:23 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 10 '26 | Sale | 15.75 | 828 | 13,041 | 3,935,608 | Apr 10 06:23 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 02 '26 | Sale | 18.23 | 260,000 | 4,741,066 | 5,144,998 | Apr 06 06:51 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Apr 06 '26 | Sale | 16.59 | 589,257 | 9,777,898 | 4,555,741 | Apr 06 06:51 PM |
| FULC | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Dec 08 '25 | Sale | 13.98 | 4,175,139 | 58,377,021 | 6,053,960 | Dec 10 04:42 PM |
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Nov 20 '25 | Sale | 40.13 | 5,133 | 205,975 | 166,642 | Nov 24 05:43 PM |
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Nov 21 '25 | Sale | 39.50 | 25,183 | 994,728 | 159,033 | Nov 24 05:43 PM |
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Nov 17 '25 | Sale | 40.59 | 81,987 | 3,328,081 | 184,619 | Nov 19 08:43 PM |
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Nov 18 '25 | Sale | 39.57 | 6,922 | 273,904 | 182,527 | Nov 19 08:43 PM |
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Nov 19 '25 | Sale | 40.01 | 47,442 | 1,898,173 | 168,193 | Nov 19 08:43 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 28 '25 | Sale | 27.42 | 124,311 | 3,408,230 | 1,055,749 | Oct 30 06:40 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 29 '25 | Sale | 25.22 | 251,518 | 6,343,284 | 804,231 | Oct 30 06:40 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 30 '25 | Sale | 25.12 | 24,579 | 617,424 | 779,652 | Oct 30 06:40 PM |
|
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 24 '25 | Sale | 39.50 | 311,000 | 12,284,500 | 219,867 | Oct 28 09:05 PM |
| SION | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 28 '25 | Sale | 39.58 | 62,610 | 2,478,104 | 209,391 | Oct 28 09:05 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 23 '25 | Sale | 28.01 | 76,880 | 2,153,409 | 1,324,346 | Oct 27 08:04 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 24 '25 | Sale | 28.01 | 53,345 | 1,494,193 | 1,271,001 | Oct 27 08:04 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 27 '25 | Sale | 28.12 | 90,941 | 2,557,261 | 1,180,060 | Oct 27 08:04 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 20 '25 | Sale | 29.67 | 92,023 | 2,730,483 | 0 | Oct 22 07:48 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 21 '25 | Sale | 28.11 | 25,027 | 703,509 | 1,401,226 | Oct 22 07:48 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 15 '25 | Sale | 30.55 | 51,363 | 1,569,313 | 82,836 | Oct 17 06:03 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 16 '25 | Sale | 29.45 | 151,803 | 4,470,604 | 57,920 | Oct 17 06:03 PM |
| VOR | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 17 '25 | Sale | 29.39 | 260,859 | 7,667,444 | 15,104 | Oct 17 06:03 PM |
| ANTX | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Aug 09 '24 | Sale | 1.08 | 3,525,094 | 3,807,102 | 300,853 | Aug 13 05:03 PM |
| KALA | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 26 '22 | Sale | 0.36 | 1,005,686 | 365,667 | 7,039,613 | May 26 05:09 PM |
| KALA | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 23 '22 | Sale | 0.65 | 1,250,000 | 812,500 | 9,624,613 | May 25 05:17 PM |
| KALA | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 24 '22 | Sale | 0.51 | 144,805 | 73,851 | 9,479,808 | May 25 05:17 PM |
| KALA | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | May 25 '22 | Sale | 0.42 | 1,434,509 | 602,494 | 8,045,299 | May 25 05:17 PM |
| PHAT | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Mar 11 '21 | Sale | 43.75 | 710,000 | 31,062,500 | 3,115,008 | Mar 15 04:36 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | Former 10% Owner | Dec 02 '20 | Sale | 32.39 | 30,939 | 1,002,261 | 4,568,464 | Dec 04 04:30 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | Former 10% Owner | Dec 03 '20 | Sale | 29.03 | 207,604 | 6,027,391 | 4,360,860 | Dec 04 04:30 PM |
| PCVX | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Oct 07 '20 | Sale | 50.95 | 98,597 | 5,023,527 | 5,169,254 | Oct 09 04:22 PM |
| PCVX | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Oct 08 '20 | Sale | 50.69 | 167,661 | 8,498,065 | 5,001,593 | Oct 09 04:22 PM |
| PCVX | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Sep 29 '20 | Sale | 52.08 | 80,707 | 4,202,987 | 5,408,474 | Oct 01 05:25 PM |
| PCVX | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Sep 30 '20 | Sale | 50.27 | 124,656 | 6,265,871 | 5,283,818 | Oct 01 05:25 PM |
| TGTX | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Sep 09 '20 | Sale | 25.81 | 158,589 | 4,092,738 | 12,629,868 | Sep 11 04:31 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 30 '20 | Sale | 22.15 | 61,901 | 1,371,237 | 5,210,088 | Jul 02 04:46 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jul 01 '20 | Sale | 21.87 | 25,527 | 558,311 | 5,184,561 | Jul 02 04:46 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jul 02 '20 | Sale | 22.04 | 44,153 | 972,969 | 5,140,408 | Jul 02 04:46 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 25 '20 | Sale | 25.05 | 11,568 | 289,768 | 5,410,744 | Jun 29 06:31 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 26 '20 | Sale | 23.31 | 86,706 | 2,020,848 | 5,324,038 | Jun 29 06:31 PM |
| RYTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 29 '20 | Sale | 22.19 | 52,049 | 1,154,999 | 5,271,989 | Jun 29 06:31 PM |
| VSTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Jun 25 '20 | Sale | 1.91 | 1,161,300 | 2,219,941 | 16,142,051 | Jun 29 06:29 PM |
| VSTM | RA CAPITAL MANAGEMENT, L.P. | 10% Owner | Apr 27 '20 | Sale | 2.31 | 1,301,300 | 3,002,099 | 17,303,351 | Apr 29 04:30 PM |
| CRIS | RA CAPITAL MANAGEMENT, LLC | 10% Owner | Apr 15 '08 | Sale | 1.40 | 1,300,000 | 1,820,000 | 6,250,564 | Apr 17 05:49 PM |
