Hoth Therapeutics, Inc. (HOTH) Files EMA Application for Global Expansion of HT-001 Skin Therapy

In this article, we will be taking a look at the 15 Best Biotech Penny Stocks to Invest in Right Now. Hoth Therapeutics, Inc. is one of them.

Hoth Therapeutics, Inc. (NASDAQ:HOTH) is advancing next-generation therapies across dermatology, oncology, and neurology, with a robust pipeline that includes proprietary platforms like BioLexa for antimicrobials and HT-ALZ for neurodegenerative conditions. The company focuses on innovative solutions for unmet medical needs, including eczema, chronic wounds, mast cell cancers, and neuroinflammation. The stock stands fifteenth on our list among the best penny stocks. 

In September 2025, Hoth Therapeutics, Inc. (NASDAQ:HOTH) announced key developments across its programs. HT-001, a topical therapy for skin toxicities caused by EGFR inhibitor cancer treatments, is expanding globally with a Clinical Trial Application submitted to the European Medicines Agency. European enrollment is expected to begin in early 2026, supplementing ongoing U.S. trials and addressing a significant unmet need.

Meanwhile, HT-KIT, targeting rare mast cell cancers, completed its Good Laboratory Practice (GLP) bioanalytical phase and is moving into formal toxicology studies, meeting crucial regulatory milestones. The business also launched a veteran obesity program, entering metabolic disorder research and strengthening its pipeline through strategic collaborations.

On the financial front, Hoth Therapeutics, Inc. (NASDAQ:HOTH) is taking a progressive approach by expanding its treasury reserve to include up to $1 million in Bitcoin, Ethereum, and Solana, signaling a focus on asset diversification and innovative capital management.

While we acknowledge the potential of HOTH as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock.

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