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Soleno Therapeutics (SLNO) Jumps 13.46% as Competitor Fails Prader-Willi Treatment Trial

By Angelica Ballesteros | September 25, 2025, 10:23 AM

We recently published 10 Stocks Crushing Wall Street, AI Stocks Dominate. Soleno Therapeutics Inc. (NASDAQ:SLNO) is one of the top performers on Tuesday.

Soleno Therapeutics extended its winning streak to a third consecutive day on Wednesday, jumping 13.46 percent to finish at $64.50 apiece, attracting investor funds after its competitor failed in its drug clinical trial for a treatment candidate for Prader-Willi syndrome (PWS).

On Wednesday, Soleno Therapeutics, Inc.’s (NASDAQ:SLNO) competitor, Acadia Pharmaceuticals Inc., announced that the third phase of its clinical trial for the potential treatment for PWS “did not demonstrate a statistically significant improvement” over placebo on the study’s primary endpoint.

Soleno Therapeutics (SLNO) Jumps 13.46% as Competitor Fails Prader-Willi Treatment Trial
Romaset/Shutterstock.com

Following the results, the latter said that it was no longer pursuing the development of the drug candidate.

The drop removed a significant threat to Soleno Therapeutics, Inc.’s (NASDAQ:SLNO) own PWS drug Vykat, which was approved by the Food and Drug Administration to treat hyperphagia in patients with PWS.

Vykat is also the only FDA-approved drug to treat such a condition.

While we acknowledge the potential of SLNO as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and have limited downside risk. If you are looking for an extremely cheap AI stock that is also a major beneficiary of Trump tariffs and onshoring, see our free report on the best short-term AI stock.

READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now.

Disclosure: None. This article is originally published at Insider Monkey.

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