DSGN

Design Therapeutics Inc

10.77

Nov 11 • 3:59 PM ET +0.12 (1.13%)

10.77

Aftermarket • 4:15 PM ET 0.00 (0.00%)

Healthcare Biotechnology USA Small NASD

Peers: LRMR LXEO DYN SLDB WVE PEPG TRDA SRPT RARE STOK

| Held by: VTI XBI IWM VXF IWO DFAS IBB FESM VTWO SCHA

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Index	RUT
Market Cap	689.67M
Enterprise Value	483.57M
Income	-74.09M
Sales	0.00M
Book/sh	3.17
Cash/sh	3.26
Dividend Est.	-
Dividend TTM	-
Dividend Ex-Date	-
Dividend Gr. 3/5Y	- -
Payout	-
Employees	124
IPO	Mar 26, 2021

P/E	-
Forward P/E	-
PEG	-
P/S	-
P/B	3.40
P/C	3.31
P/FCF	-
EV/EBITDA	-
EV/Sales	-
Quick Ratio	16.78
Current Ratio	16.78
Debt/Eq	0.01
LT Debt/Eq	0.01
Option/Short	Yes / Yes

EPS (ttm)	-1.20
EPS next Y	-1.55
EPS next Q	-0.40
EPS this Y	-8.89%
EPS next Y	-16.95%
EPS next 5Y	-15.32%
EPS past 3/5Y	-2.32% -52.23%
Sales past 3/5Y	- -
EPS Y/Y TTM	-1.42%
Sales Y/Y TTM	-
EPS Q/Q	-7.88%
Sales Q/Q	-
Earnings	Nov 04 AMC
EPS/Sales Surpr.	7.00% -

Insider Own	44.74%
Insider Trans	0.00%
Inst Own	59.85%
Inst Trans	25.97%
ROA	-34.57%
ROE	-36.87%
ROIC	-36.31%
Gross Margin	-
Oper. Margin	-
Profit Margin	-
SMA20	2.09%
SMA50	-9.33%
SMA200	-11.61%
Trades

Shs Outstand	63.79M
Shs Float	35.38M
Short Float	17.84%
Short Ratio	10.94
Short Interest	6.31M
52W High	17.25 -37.57%
52W Low	6.81 58.15%
Volatility	7.37% 6.51%
ATR (14)	0.66
RSI (14)	48.34
Beta	1.75
Rel Volume	0.79
Avg Volume	577.01K
Volume	455,717

Perf Week	1.32%
Perf Month	10.12%
Perf Quarter	-25.16%
Perf Half Y	-31.05%
Perf YTD	14.82%
Perf Year	38.79%
Perf 3Y	435.82%
Perf 5Y	-46.92%
Perf 10Y	-
Recom	1.00
Target Price	21.57
Prev Close	10.65
Price	10.77
Change %	1.13%

Consensus

Strong Buy

Avg. Price Target

$21.57

Implied Upside

+100.3%

Analysts12incl. previous ratings

Rating Distribution9 Buy · 3 Hold · 0 Sell

Date	Action	Analyst	Rating Change	Price Target Change	Implied Upside
Oct 02, 2026	Initiated	WWells Fargo	Overweight	$26	+141.4%
May 12, 2026	Initiated	CCantor Fitzgerald	Overweight
Mar 16, 2026	Initiated	JJefferies	Buy	$15	+39.3%
Jan 07, 2026	Initiated	OOppenheimer	Outperform	$18	+67.1%
Dec 03, 2025	Upgrade	LLeerink Partners	Market Perform → Outperform	$14	+30.0%
Dec 03, 2025	Initiated	CCraig Hallum	Buy	$15	+39.3%
Nov 20, 2025	Upgrade	RRBC Capital Mkts	Sector Perform → Outperform	$13	+20.7%
May 07, 2024	Upgrade	PPiper Sandler	Neutral → Overweight	$6 → $12	+11.4%
Nov 14, 2023	Downgrade	PPiper Sandler	Overweight → Neutral	$42 → $6	-44.3%
Aug 15, 2023	Downgrade	WWedbush	Outperform → Neutral	$19 → $6	-44.3%
Aug 15, 2023	Downgrade	SSVB Securities	Outperform → Market Perform	$6	-44.3%
Aug 15, 2023	Downgrade	RRBC Capital Mkts	Outperform → Sector Perform	$23 → $7	-35.0%
May 04, 2023	Upgrade	GGoldman	Sell → Neutral	$6	-44.3%
Jun 10, 2022	Initiated	WWedbush	Outperform	$21	+95.0%
May 02, 2022	Initiated	RRBC Capital Mkts	Outperform	$30	+178.6%
Jan 19, 2022	Initiated	GGoldman	Sell	$10	-7.1%
Apr 20, 2021	Initiated	SSVB Leerink	Outperform	$36	+234.3%
Apr 20, 2021	Initiated	PPiper Sandler	Overweight	$42	+290.0%
Apr 20, 2021	Initiated	GGoldman	Neutral	$28	+160.0%

Nov-04-26 04:01PM	Design Therapeutics Announces Third Quarter 2026 Financial Results and Recent Business Updates (GlobeNewswire) -9.03%
Oct-02-26 09:40AM	Nike downgraded, Airbnb upgraded: Wall Street's top analyst calls (The Fly)
Sep-02-26 08:00AM	Design Therapeutics to Participate in 2026 Cantor Fitzgerald Global Healthcare Conference (GlobeNewswire)
Aug-03-26 08:00AM	Design Therapeutics Provides RESTORE-FA Clinical Development Update and Reports Second Quarter 2026 Financial Results (GlobeNewswire)
Jun-30-26 08:00AM	Design Therapeutics Announces Initiation of Patient Dosing in Phase 1 Multiple Ascending Dose Trial of DT-818 for Myotonic Dystrophy Type-1 (GlobeNewswire)
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May-28-26 08:00AM	Design Therapeutics to Participate in 2026 Jefferies Global Healthcare Conference (GlobeNewswire)
May-18-26 11:02AM	This Biotech Leader Ran Up As Much As 18% - And Then Lost It All (Investor's Business Daily) -25.54%
10:02AM	Design Therapeutics Shares Jump on Encouraging Friedreich Ataxia Trial Results (DSGN) (InvestorsHub)
07:00AM	Design Therapeutics Announces Four-Week IV Data from the RESTORE-FA Trial of DT-216P2 Demonstrating Clinical Improvements and Comprehensive Biomarker Activity in Friedreich Ataxia (GlobeNewswire)
May-17-26 04:00PM	Design Therapeutics to Host Investor Webcast to Review Data from RESTORE-FA Trial of DT-216P2 for Friedreich's Ataxia on Monday, May 18, 2026 (GlobeNewswire)
Apr-29-26 07:00PM	Design Therapeutics Inc (DSGN) Q1 2026 Earnings Call Highlights: Promising Progress in ... (GuruFocus.com) +23.26% -13.87%
Apr-28-26 04:01PM	Design Therapeutics Announces First Quarter 2026 Financial Results and Recent Business Updates (GlobeNewswire)
Mar-09-26 04:01PM	Design Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Recent Business Updates (GlobeNewswire)
Feb-26-26 05:53AM	Design Therapeutics Highlights GeneTAC Pipeline, FA Data Timeline and DM1 Dosing Plans at Oppenheimer Conference (MarketBeat)
Feb-18-26 08:00AM	Design Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire)
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Nov-26-25 08:00AM	Design Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire)
Nov-20-25 09:21AM	Here Are Thursdays Top Wall Street Analyst Research Calls: AON, Apollo Global, Bullish, Jack Henry, Marsh & McClennan, Nasdaq, NVIDIA, and More (24/7 Wall St.) +7.22%
Nov-05-25 04:01PM	Design Therapeutics Announces Plans to Initiate Patient Dosing of DT-818 in Myotonic Dystrophy Type-1 (DM1) in the First Half of 2026 and Reports Third Quarter 2025 Financial Results (GlobeNewswire)
Sep-10-25 04:01PM	Design Therapeutics Appoints Justin Gover to Board of Directors (GlobeNewswire) -7.68%
Aug-27-25 08:00AM	Design Therapeutics to Participate in the 2025 Cantor Global Healthcare Conference (GlobeNewswire)
Aug-07-25 04:01PM	Design Therapeutics Highlights Progress Across Lead GeneTAC Programs and Reports Second Quarter 2025 Financial Results (GlobeNewswire) -8.74% +7.81%
Jun-04-25 07:00AM	Design Therapeutics Announces Start of Friedreich Ataxia Patient Dosing Ex-U.S. in its RESTORE-FA Phase 1/2 Multiple-Ascending Dose Trial of DT-216P2 (GlobeNewswire)
May-28-25 08:00AM	Design Therapeutics to Participate in 2025 Jefferies Global Healthcare Conference (GlobeNewswire)
May-13-25 08:00AM	Design Therapeutics to Participate in 2025 RBC Capital Markets Healthcare Conference (GlobeNewswire)
May-07-25 04:01PM	Design Therapeutics Highlights Momentum Across Lead GeneTAC Programs and Reports First Quarter 2025 Financial Results (GlobeNewswire) -8.26% +5.71%
May-02-25 07:58AM	Design Therapeutics reports positive outcomes from trial of DT-168 eye drops (Clinical Trials Arena)
May-01-25 08:00AM	Design Therapeutics Announces Favorable Phase 1 Data for DT-168 Supporting Advancement into Phase 2 Biomarker Trial for Patients with Fuchs Endothelial Corneal Dystrophy (GlobeNewswire)
Apr-21-25 04:01PM	Design Therapeutics to Present Phase 1 Data for Fuchs Endothelial Corneal Dystrophy Program at Eyecelerator @ Park City 2025 (GlobeNewswire) +10.31%
Apr-17-25 08:00AM	Design Therapeutics Appoints Veteran Industry Executive Chris Storgard, M.D., as Chief Medical Officer (GlobeNewswire)
07:00AM	Bright Peak Therapeutics Appoints John Schmid to its Board of Directors (GlobeNewswire)
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Mar-12-25 12:00PM	Design Therapeutics (DSGN) Upgraded to Buy: Here's Why (Zacks) -6.94%
Mar-10-25 07:07AM	Design Therapeutics Highlights Progress Across Lead GeneTAC Programs and Reports Fourth Quarter and Full Year 2024 Financial Results (GlobeNewswire)
Mar-03-25 08:00AM	Design Therapeutics to Participate in Leerink's Global Healthcare Conference (GlobeNewswire) -7.00%
Nov-13-24 08:00AM	Design Therapeutics to Participate in Multiple Upcoming Investor Conferences (GlobeNewswire) +8.54%
Nov-07-24 04:01PM	Design Therapeutics Announces Third Quarter 2024 Financial Results and Reviews Near-term Milestones for GeneTACTM Portfolio (GlobeNewswire)
Sep-10-24 08:00AM	Design Therapeutics to Participate in the 2024 Cantor Global Healthcare Conference (GlobeNewswire) +15.69%
Aug-21-24 09:55AM	Wall Street Analysts Think Design Therapeutics (DSGN) Could Surge 39.72%: Read This Before Placing a Bet (Zacks)
Aug-05-24 08:00AM	Design Therapeutics Announces Second Quarter 2024 Financial Results and Reviews Near-term Milestones for GeneTAC Portfolio (GlobeNewswire)
May-22-24 08:50PM	The 100%+ Club: Piper Sandler's 3 Top Picks for Triple-Digit Gains (InvestorPlace)
May-10-24 03:36PM	Design Therapeutics Inc (DSGN) Q1 2024 Earnings: A Detailed Financial and Strategic Review (GuruFocus.com)
May-08-24 11:55PM	DSGN Stock Earnings: Design Therapeutics Beats EPS for Q1 2024 (InvestorPlace)
04:05PM	Design Therapeutics Announces First Quarter 2024 Financial Results and Highlights Upcoming Program Milestones (GlobeNewswire)
May-07-24 07:12AM	--Piper Sandler Upgrades Design Therapeutics to Overweight From Neutral (MT Newswires) +28.49%
06:30AM	Design Therapeutics to Participate in the 2024 RBC Capital Markets Global Healthcare Conference (GlobeNewswire)
Mar-20-24 10:31AM	Design Therapeutics, Inc. (NASDAQ:DSGN) Q4 2023 Earnings Call Transcript (Insider Monkey) +11.97%
06:58AM	Q4 2023 Design Therapeutics Inc Earnings Call (Thomson Reuters StreetEvents)
Mar-19-24 08:53PM	DSGN Stock Earnings: Design Therapeutics Beats EPS for Q4 2023 (InvestorPlace)
05:33PM	Design Therapeutics Inc (DSGN) Reports Full Year 2023 Financial Results and Pipeline Progress (GuruFocus.com)
04:01PM	Design Therapeutics Outlines Progress Across GeneTAC Platform and Announces Fourth Quarter and Full Year 2023 Financial Results (GlobeNewswire)
Mar-12-24 06:30AM	Design Therapeutics to Webcast Fourth Quarter and Full Year 2023 Financial Results and Comprehensive Portfolio Update (GlobeNewswire)
Dec-18-23 12:00PM	Design Therapeutics, Inc. (DSGN) Upgraded to Buy: Here's What You Should Know (Zacks)
Nov-14-23 07:28PM	Design Therapeutics Inc (DSGN) Reports Q3 2023 Financials, Plans Strategic Update (GuruFocus.com) +11.71%
Nov-13-23 04:05PM	Design Therapeutics Reports Third Quarter 2023 Financial Results and Plans for a Comprehensive Portfolio Update in Early 2024 (GlobeNewswire)
Aug-15-23 03:02PM	Why Shares of Design Therapeutics Are Plummeting on Tuesday (Motley Fool) -70.46%
09:59AM	Redfin upgraded, CSSE downgraded: Wall Street's top analyst calls (The Fly)
02:34AM	4 big analyst cuts: Urban Outfitters has 'limited' EPS upside, per Citi (Investing.com)
Aug-14-23 04:05PM	Design Therapeutics Provides Pipeline Update and Reports Second Quarter 2023 Financial Results (GlobeNewswire)
04:01PM	Design Therapeutics Reports Initial Results from Phase 1 Multiple-Ascending Dose Study of DT-216 for the Treatment of Friedrich Ataxia (GlobeNewswire)
Jun-18-23 08:03AM	Pleasing Signs As A Number Of Insiders Buy Design Therapeutics Stock \ (Simply Wall St.)
May-31-23 06:30AM	Design Therapeutics to Present at the 2023 Jefferies Healthcare Conference (GlobeNewswire) -6.01%
May-09-23 04:05PM	Design Therapeutics Provides Pipeline Updates and Reports First Quarter 2023 Financial Results (GlobeNewswire) -11.66%
May-08-23 06:05AM	We're Hopeful That Design Therapeutics (NASDAQ:DSGN) Will Use Its Cash Wisely (Simply Wall St.)
Apr-24-23 06:30AM	Design Therapeutics to Present Preclinical Data on its GeneTAC Small Molecule, DT-168, for the Treatment of Fuchs Endothelial Corneal Dystrophy at ARVO 2023 (GlobeNewswire)
Apr-11-23 09:55AM	Why Design Therapeutics (DSGN) Stock Is Going Nowhere But Down (InvestorPlace)
Apr-04-23 02:47PM	Down More Than 60%: Analysts Say Buy These 3 Beaten-Down Stocks Before They Rebound (TipRanks) -7.32%
Mar-14-23 04:05PM	Design Therapeutics Highlights Pipeline Progress and Reports Fourth Quarter and Full Year 2022 Financial Results (GlobeNewswire)
Mar-09-23 06:33AM	Daily Vickers Top Insider Picks for 03/09/2023 (Argus Research)
Feb-08-23 06:30AM	Design Therapeutics to Participate in the SVB Securities Virtual Global Biopharma Conference (GlobeNewswire) -8.79%
Dec-21-22 06:46AM	Daily Vickers Top Buyers & Sellers for 12/21/2022 (Argus Research) +5.33%
Dec-14-22 05:15AM	Independent Director Rodney Lappe Just Bought 15% More Shares In Design Therapeutics, Inc. (NASDAQ:DSGN) (Simply Wall St.)
Dec-07-22 04:01PM	Design Therapeutics Reports Positive Data from Single-Ascending Dose Trial of DT-216 for the Treatment of Friedreich Ataxia and Portfolio Progress (GlobeNewswire) -6.00% -33.33%
Nov-28-22 10:37AM	Companies Like Design Therapeutics (NASDAQ:DSGN) Are In A Position To Invest In Growth (Simply Wall St.)
Nov-03-22 04:05PM	Design Therapeutics Highlights Pipeline Progress and Upcoming Milestones and Reports Third Quarter 2022 Financial Results (GlobeNewswire)
Oct-17-22 04:05PM	Design Therapeutics to Present Preclinical Data Highlighting the Potential of its GeneTAC Small Molecule, DT-216, for the Treatment of Friedreich Ataxia at ICAR 2022 (GlobeNewswire)
Sep-22-22 06:30AM	Design Therapeutics to Present at the 2022 Jefferies Cell and Genetic Medicine Summit (GlobeNewswire)
Aug-08-22 04:05PM	Design Therapeutics Highlights Upcoming Milestones and Reports Second Quarter 2022 Financial Results (GlobeNewswire)
Aug-03-22 06:30AM	Design Therapeutics to Participate in the 2022 Wedbush PacGrow Virtual Healthcare Conference (GlobeNewswire) +6.33%
Jun-21-22 09:57AM	Companies Like Design Therapeutics (NASDAQ:DSGN) Are In A Position To Invest In Growth (Simply Wall St.) +6.24%
Jun-01-22 06:30AM	Design Therapeutics to Present at the 2022 Jefferies Healthcare Conference (GlobeNewswire)
May-09-22 04:05PM	Design Therapeutics Highlights Clinical and Research Progress and Reports First Quarter 2022 Financial Results (GlobeNewswire)
Mar-30-22 06:30AM	Design Therapeutics Completes Dosing in First Patient Cohort of Phase 1 Trial of DT-216 GeneTAC Molecule for the Treatment of Friedreich Ataxia (GlobeNewswire)
Mar-23-22 02:53PM	Design Therapeutics, Inc. (NASDAQ:DSGN) insiders placed bullish bets worth US$1.2m in the last 12 months (Simply Wall St.)
Mar-10-22 04:02PM	Design Therapeutics Reports Pipeline and Business Progress and Fourth Quarter and Full Year 2021 Financial Results (GlobeNewswire)
Mar-09-22 06:30AM	Design Therapeutics Announces Preclinical Data Highlighting Novel GeneTAC Therapy for the Treatment of Fuchs Endothelial Corneal Dystrophy to be Presented at ARVO 2022 (GlobeNewswire) +9.41%
Feb-28-22 04:05PM	Design Therapeutics Announces FDA Clearance of Investigational New Drug Application for First GeneTAC Molecule for Friedreich Ataxia (GlobeNewswire)
Feb-10-22 06:30AM	Design Therapeutics to Present at the SVB Leerink 11th Annual Global Healthcare Conference (GlobeNewswire) +7.02%
Feb-01-22 04:05PM	Design Therapeutics Appoints Drug Development Expert, Jae Kim, M.D., as Chief Medical Officer (GlobeNewswire)
Jan-19-22 12:51PM	Design Therapeutics Shares Fall As Goldman Sachs Initiates With Sell Rating (Benzinga) -5.86%
Dec-23-21 05:00AM	Design Therapeutics (NASDAQ:DSGN) Is In A Good Position To Deliver On Growth Plans (Simply Wall St.) +5.09%
Nov-09-21 04:05PM	Design Therapeutics Reports Pipeline Progress and Third Quarter 2021 Results (GlobeNewswire)
Sep-24-21 07:55AM	Design Therapeutics, Inc. (NASDAQ:DSGN) insiders placed bullish bets worth US$1.2m in the last 12 months (Simply Wall St.)
Sep-08-21 06:30AM	Design Therapeutics Announces Positive Preclinical Data Highlighting Disease-Modifying Potential of its Novel DM1 GeneTACs as a Treatment for Myotonic Dystrophy Type-1 (GlobeNewswire)
Sep-03-21 07:33AM	4 Stocks Insiders Are Buying (Benzinga)
Aug-09-21 04:05PM	Design Therapeutics Reports GeneTAC Portfolio Progress and Second Quarter 2021 Results (GlobeNewswire) +6.19%
Jun-26-21 04:30AM	We're Hopeful That Design Therapeutics (NASDAQ:DSGN) Will Use Its Cash Wisely (Simply Wall St.)
Jun-07-21 04:10PM	Design Therapeutics to Participate in Goldman Sachs 42nd Annual Global Healthcare Conference (GlobeNewswire)
04:05PM	Design Therapeutics Expands Board of Directors with Key Appointments (GlobeNewswire)
May-10-21 04:05PM	Design Therapeutics Announces Business Highlights and Reports First Quarter 2021 Financial Results (GlobeNewswire) -6.82%
Mar-30-21 04:05PM	Design Therapeutics Announces Closing of Initial Public Offering and Full Exercise of Underwriters Option to Purchase Additional Shares (GlobeNewswire) -13.20%
Mar-25-21 11:56PM	Design Therapeutics Announces Pricing of Initial Public Offering (GlobeNewswire)

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Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Logos Global Master Fund LP	Director	Nov 18 '25	Proposed Sale	7.43	120,000	891,600		Nov 18 04:28 PM
Logos Global Master Fund LP	Director	Nov 14 '25	Proposed Sale	7.06	620,000	4,377,200		Nov 14 04:18 PM

Design Therapeutics, Inc. operates as a biotechnology company that develops therapies for serious degenerative disorders. It is created to design, develop and commercialize a novel class of small molecule therapeutic candidates (GeneTACs) designed to directly address the underlying basis of genetic disease. The company was founded by Pratik Shah and Aseem Z. Ansari on December 18, 2017 and is headquartered in Carlsbad, CA.

Co-FounderMr. Pratik Shah Ph.D.

Chief Operating OfficerDr. Sean Jeffries Ph.D.

Chief Medical OfficerDr. Chris M. Storgard M.D.

Co-Founder & Scientific AdvisorDr. Aseem Z. Ansari Ph.D.

Chief Accounting OfficerMs. Julie D. Burgess CPA

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