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AGEN

Agenus Inc

6.12

Jul 13 • 03:59PM ET +2.77 (82.69%)

6.11

Aftermarket • 07:59PM ET -0.01 (-0.14%)

Healthcare Biotechnology USA Micro NASD

Today, 3:40 PMAgenus pivots botensilimab‑balstilimab to earlier‑stage colon cancer trial, stops advanced study, aligns strategy with up‑to‑$340 million private placement

Peers: CNTB GALT IMUX KZIA SPRO VRCA MOLN HURA ORMP PLX

| Held by: VTI IWM VXF IWN IWO IWC QQQS RSSL ITWO BTEC

Scroll to Statements

Index	RUT
Market Cap	254.85M
Enterprise Value	517.55M
Income	64.39M
Sales	123.87M
Book/sh	-5.74
Cash/sh	0.84
Dividend Est.	-
Dividend TTM	-
Dividend Ex-Date	-
Dividend Gr. 3/5Y	- -
Payout	-
Employees	81
IPO	Feb 04, 2000

P/E	3.67
Forward P/E	-
PEG	-
P/S	2.06
P/B	-
P/C	7.28
P/FCF	-
EV/EBITDA	34.07
EV/Sales	4.18
Quick Ratio	0.38
Current Ratio	0.38
Debt/Eq	-
LT Debt/Eq	-
Option/Short	Yes / Yes

EPS (ttm)	1.67
EPS next Y	-0.16
EPS next Q	0.05
EPS this Y	135.00%
EPS next Y	-124.06%
EPS next 5Y	39.06%
EPS past 3/5Y	93.99% 82.55%
Sales past 3/5Y	5.22% 5.31%
EPS Y/Y TTM	120.02%
Sales Y/Y TTM	24.46%
EPS Q/Q	198.88%
Sales Q/Q	40.18%
Earnings	May 11 BMO
EPS/Sales Surpr.	-51.43% -73.98%

Insider Own	9.28%
Insider Trans	0.00%
Inst Own	19.75%
Inst Trans	-2.72%
ROA	33.42%
ROE	-
ROIC	-
Gross Margin	93.33%
Oper. Margin	6.30%
Profit Margin	51.98%
SMA20	84.31%
SMA50	80.15%
SMA200	67.87%
Trades

Shs Outstand	38.52M
Shs Float	37.78M
Short Float	15.87%
Short Ratio	6.83
Short Interest	5.99M
52W High	7.34 -16.62%
52W Low	2.71 125.83%
Volatility	22.65% 11.05%
ATR (14)	0.60
RSI (14)	83.19
Beta	1.56
Rel Volume	198.65
Avg Volume	877.30K
Volume	174,277,926

Perf Week	79.47%
Perf Month	99.35%
Perf Quarter	54.55%
Perf Half Y	63.20%
Perf YTD	94.90%
Perf Year	-13.31%
Perf 3Y	-83.46%
Perf 5Y	-94.47%
Perf 10Y	-93.49%
Recom	1.00
Target Price	19.00
Prev Close	3.35
Price	6.12
Change	82.69%

Date	Action	Analyst	Rating Change	Price Target Change
Today	Reiterated	H.C. Wainwright	Buy	$23 → $30
Jun-04-25	Upgrade	H.C. Wainwright	Neutral → Buy	$25
Jul-19-24	Downgrade	Robert W. Baird	Outperform → Neutral	$35 → $8
Jul-18-24	Downgrade	William Blair	Outperform → Mkt Perform
Jul-18-24	Downgrade	H.C. Wainwright	Buy → Neutral	$9
Jun-06-23	Initiated	Robert W. Baird	Outperform	$8
Jun-06-23	Initiated	Robert W. Baird	Outperform	$60 → $80
Feb-28-23	Resumed	H.C. Wainwright	Buy	$8
Sep-28-22	Initiated	SMBC Nikko	Outperform	$5
Dec-16-21	Initiated	H.C. Wainwright	Buy	$12
Nov-19-19	Resumed	B. Riley FBR	Buy	$6
Apr-22-19	Initiated	B. Riley FBR	Buy
Oct-28-16	Downgrade	H.C. Wainwright	Buy → Neutral	$10 → $5
Oct-27-16	Reiterated	Maxim Group	Buy
Mar-11-16	Upgrade	Maxim Group	Hold → Buy	$7
Dec-16-15	Initiated	Jefferies	Buy
Oct-27-15	Downgrade	Maxim Group	Buy → Hold
Jul-27-15	Reiterated	MLV & Co	Buy	$9 → $11
Jun-11-15	Initiated	Oppenheimer	Outperform	$14
Jan-12-15	Reiterated	Maxim Group	Buy	$10 → $11

Show Previous Ratings

Today 02:25PM	AGEN Stock Eyes Best Day Ever Following Strategic Shift To Earlier Colon Cancer Treatment (Stocktwits) +82.69%
12:53PM	Agenus shares surge as company secures up to $340M to advance colon cancer trial (Proactive)
08:25AM	Agenus Shares Rise After Securing Up to $340 Million Financing Package (AGEN) (InvestorsHub)
08:24AM	Wall Street closes lower as chip selloff and oil surge weigh on markets (Proactive)
08:24AM	Nasdaq falls, Dow slips as oil prices rebound on fresh US-Iran fighting (Proactive)
07:46AM	Loading…
07:46AM	Agenus surges on study pivot; Apnimed lines up an IPO (BioPharma Dive)
06:59AM	Agenus rises premarket; Micron, Western Digital slide (Investing.com)
06:00AM	Agenus Announces Oversubscribed Private Placement of Up to $340 Million to Advance Registrational ROBBIN Trial of Neoadjuvant BOT+BAL in MSS Colon Cancer (Business Wire)
Jul-06-26 07:30AM	Agenus Reports Landmark BOT+BAL Data Showing 33% Three-Year Overall Survival in Refractory MSS Metastatic Colorectal Cancer Without Active Liver Metastases at ESMO GI 2026 (Business Wire)
Jun-25-26 07:00AM	Agenus Announces Three-Year Survival Data from Phase 1b BOT+BAL Study in MSS Metastatic Colorectal Cancer to be Presented at ESMO GI 2026 (Business Wire)
Jun-02-26 04:30PM	Agenus Announces Virtual 2026 Annual Shareholders Meeting (Business Wire)
May-21-26 05:00PM	Agenus Presents Phase 2 BOT+BAL Melanoma Data Showing Durable Responses and Meaningful Survival in Advanced Checkpoint-Refractory Melanoma at ASCO 2026 (Business Wire)
05:00PM	Agenus and Noetik Present ASCO 2026 Data Linking AI Analysis of Routine Pretreatment Tumor Pathology Images to Response and Survival with BOT+BAL in MSS Metastatic CRC (Business Wire)
May-15-26 04:11PM	Agenus Announces Publication of Phase 1b Botensilimab and Balstilimab Data in Post-Immunotherapy Hepatocellular Carcinoma in Liver Cancer (Business Wire) -11.73%
May-11-26 05:27PM	Agenus: Q1 Earnings Snapshot (Associated Press) -14.66% +5.52%
08:45AM	Loading…
08:45AM	Agenus Reports First Quarter 2026 Financial Results and Highlights BOT+BAL Execution Across Global Access and Phase 3 Development (Business Wire)
May-04-26 04:30PM	Agenus to Provide First Quarter 2026 Financial Report and Corporate Update (Business Wire)
Apr-21-26 10:00AM	Agenus to Present First Phase 2 Botensilimab Data in Advanced Cutaneous Melanoma at ASCO 2026 (Business Wire) -11.54%
08:00AM	Agenus Names BAP Pharma as Exclusive Global Partner for BOT+BAL Access Programs (Business Wire)
Apr-17-26 04:43PM	Agenus Reports Phase II Data Demonstrating Immune Reprogramming and Durable Survival with Botensilimab, Balstilimab and agenT-797 in PD-1 Refractory Gastroesophageal Cancer (Business Wire) -7.72%
Apr-03-26 07:30AM	Agenus Announces Data from Phase II Study of BOT+BAL in Combination with agent-797 in PD-1 Refractory Gastroesophageal Cancer to be Presented at AACR 2026 (Business Wire)
Apr-01-26 07:30AM	Agenus Announces First Patient Enrolled in Global Phase 3 BATTMAN Trial of BOT+BAL Immunotherapy Combination in MSS or pMMR Metastatic Colorectal Cancer (Business Wire)
Mar-26-26 04:52PM	Agenus to Host March 2026 Stakeholder Webcast Harnessing the Immune System to Advance BOT + BAL Across Tumor Types and Expand Patient Access (Business Wire)
Mar-17-26 04:40PM	Agenus Announces Upcoming AACR 2026 Presentation Evaluating Botensilimab Plus Balstilimab in First-Line MSS Metastatic Colorectal Cancer (Business Wire) +21.28% -5.76%
Mar-16-26 07:41PM	Agenus: Q4 Earnings Snapshot (Associated Press Finance) +6.13%
07:30AM	Agenus Reports 2025 Results; BOT+BAL Advances to Phase 3 and Early Access Programs Expand Globally with Initial Revenues Recognized (Business Wire)
Mar-10-26 07:30AM	Agenus Triggers First $20M Contingent Payment Under Zydus Life Sciences Collaboration to Support BOT+BAL Manufacturing Needs (Business Wire) +6.98%
Mar-04-26 04:30PM	Agenus to Provide Fourth Quarter and Year-end 2025 Financial Report and Corporate Update (Business Wire) -8.75%
Feb-24-26 09:33AM	Agenus (AGEN) Presents New Phase 1b Clinical Data on BOT/BAL Combination for MSS mCRC (Insider Monkey)
Feb-19-26 03:15PM	Agenus Presents Biomarker Data Demonstrating Survival Stratification in MSS mCRC and Other Immunologically Cold Tumors Treated with BOT+BAL (Business Wire)
01:00PM	Loading…
Feb-09-26 01:00PM	Agenus to Present New Data at AACR-IO Exploring Systemic and Tumor Inflammation Biomarkers with BOT/BAL in Immunologically Cold Tumors (Business Wire)
Jan-28-26 08:00PM	Agenus Webcast: Zydus Manufacturing Deal Closes, France Access Expands, Phase 3 BATMAN Nears Launch (MarketBeat)
Jan-21-26 07:30AM	Agenus Expands Medical Affairs Infrastructure to Support Increasing Physician Requests for Authorized Access to Botensilimab Plus Balstilimab (Business Wire)
Jan-20-26 06:24PM	Agenus to Host First 2026 Stakeholder Webcast (Business Wire)
Jan-16-26 06:16AM	Agenus and Zydus complete $141m BOT+BAL immunotherapy collaboration deal (Pharmaceutical Business Review) -9.24%
Jan-15-26 07:01AM	Agenus Announces Closing of $141M Strategic Collaboration with Zydus Lifesciences to Advance BOT+BAL and Strengthen U.S. Manufacturing Readiness (Business Wire) -21.37%
Jan-13-26 12:00PM	Agenus (AGEN) Upgraded to Buy: What Does It Mean for the Stock? (Zacks) +8.47%
09:40AM	Are Medical Stocks Lagging ADC Therapeutics (ADCT) This Year? (Zacks)
Jan-12-26 07:30AM	France Expands National AAC Access for Agenus' Botensilimab + Balstilimab for Ovarian Cancer and Soft-Tissue Sarcomas (Business Wire) +8.70%
Dec-23-25 08:05AM	Agenus Reports Deep, Durable Responses with Botensilimab + Balstilimab in Highly Refractory Ovarian Cancer, Published in JITC (Business Wire) -5.70%
Nov-19-25 04:01PM	Agenus to Host End-of-Year Stakeholder Webcast Featuring GI Oncology Leaders and Progress of BOT/BAL (Business Wire)
Nov-18-25 08:41AM	Agenus Appoints Dr. Jose Iglesias as Chief Medical Affairs Officer to Guide Global Medical Affairs and Early-Access Programs, Including France's AAC (Business Wire)
Nov-10-25 08:40AM	Agenus (AGEN) Misses Q3 Earnings and Revenue Estimates (Zacks) +5.78%
07:37AM	Agenus: Q3 Earnings Snapshot (Associated Press Finance)
07:30AM	Agenus Reports Q3 2025 Results Showcasing Clinical and Regulatory Advances (Business Wire)
Nov-06-25 05:20PM	Intellia Therapeutics, Inc. (NTLA) Reports Q3 Loss, Misses Revenue Estimates (Zacks)
Nov-05-25 06:40PM	Innoviva (INVA) Q3 Earnings and Revenues Beat Estimates (Zacks)
01:47PM	Agenus to Provide Corporate Update and Third Quarter 2025 Financial Report (Business Wire)
Nov-03-25 05:20PM	Sarepta Therapeutics (SRPT) Reports Q3 Loss, Beats Revenue Estimates (Zacks) -6.05%
Oct-17-25 08:00AM	Agenus Reports 39% of Patients Alive at Two-Years with BOT/BAL Across Multiple Refractory Solid Tumors at ESMO 2025 (Business Wire)
Oct-16-25 07:48AM	Agenus to Host October Stakeholder Briefing Showcasing BOT/BAL Global Momentum and Post-ESMO Insights (Business Wire)
Sep-23-25 10:14AM	Are Options Traders Betting on a Big Move in Agenus tock? (Zacks)
Sep-09-25 07:43AM	France Grants Reimbursed Compassionate Access (AAC) for Agenus BOT/BAL in Refractory MSS Metastatic Colorectal Cancer (Business Wire) +19.01%
Sep-05-25 08:52AM	Agenus to Participate in the H.C. Wainwright 27th Annual Global Investment Conference (Business Wire)
Aug-28-25 10:44AM	FDA Tightens Survival Standards as Cancer Drug Pipeline Hits $866B Market Milestone (PR Newswire) -6.39%
Aug-26-25 09:37AM	Update: Agenus Aug 27 Stakeholder Webcast-Transformative IO Updates, BOT/BAL Data, BATTMAN Preview, Zydus Partnership Momentum, and MiNK Spotlight (Business Wire) +5.47%
09:19AM	What To Expect From Agenus Inc (AGEN) Q2 2025 Earnings (GuruFocus.com)
Aug-19-25 07:30AM	Agenus to Unveil BOT/BAL Strategic Advancements, Key Milestones, and Future Outlook in Virtual Stakeholder Briefing on August 27, 2025 (Business Wire)
Aug-11-25 06:55PM	Agenus (AGEN) Reports Q2 Loss, Beats Revenue Estimates (Zacks) -11.04% +12.65%
06:06PM	Agenus: Q2 Earnings Snapshot (Associated Press Finance)
07:30AM	Agenus Announces Second Quarter 2025 Financial Results and Virtual Meeting to Discuss Strategic Progress (Business Wire)
Aug-07-25 05:40PM	Gilead Sciences (GILD) Tops Q2 Earnings and Revenue Estimates (Zacks)
Aug-06-25 05:25PM	AnaptysBio, Inc. (ANAB) Reports Q2 Loss, Tops Revenue Estimates (Zacks) -10.02%
Aug-01-25 09:05AM	Zacks.com featured highlights include QuantumScape, Civeo and Agenus (Zacks)
Jul-31-25 03:00PM	QuantumScape & 2 Other Stocks to Buy for Earnings Acceleration (Zacks) -6.44%
07:30AM	Agenus to Provide Corporate Update and Second Quarter 2025 Financial Report (Business Wire)
Jul-30-25 09:40AM	Is CVS Health (CVS) Stock Outpacing Its Medical Peers This Year? (Zacks)
Jul-29-25 03:46PM	Biotech Underdogs Line Up for Pivotal Shots at Game-Changing Cancer Treatments (PR Newswire) -7.40%
Jul-25-25 12:46PM	Agenus to Highlight Emerging Survival Plateaus with Botensilimab/Balstilimab in Oral Presentation of Study in Refractory Patients Across Five Tumor Types at ESMO 2025 (Business Wire)
Jul-24-25 10:45AM	VKTX Stock Down on Wider-Than-Expected Loss in Q2, Nil Sales (Zacks)
Jul-22-25 09:15AM	From Diagnosis to Surgery: How AI Tech Is Quietly Reshaping Healthcare Profits (PR Newswire)
Jul-17-25 01:07PM	AstraZeneca's AL Amyloidosis Drug Misses Goal in Late-Stage Studies (Zacks) +5.66%
11:34AM	MDGL Stock Soars 11% on New Patent Protecting Rezdiffra Dosing Rights (Zacks)
07:00AM	US FDA Approves GSKs SHINGRIX in a Prefilled Syringe Presentation (Business Wire)
Jul-15-25 08:32AM	AstraZeneca Meets All Key Goals in Phase III Hypertension Study (Zacks) -8.93%
08:28AM	Ultragenyx Pharmaceuticals Gets CRL for UX111 Gene Therapy for MPS IIIA (Zacks)
Jul-14-25 09:40AM	Is Agenus (AGEN) Stock Outpacing Its Medical Peers This Year? (Zacks)
09:39AM	Agenus (AGEN) Surges 19.3%: Is This an Indication of Further Gains? (Zacks)
Jul-11-25 07:30AM	MiNK Therapeutics Announces Publication of Complete Remission Following Allogeneic iNKT Cell Therapy in Metastatic Testicular Cancer (GlobeNewswire) +19.26%
Jul-10-25 09:11AM	KALV Stock Moves More Than 30% in a Week: What Is Driving This Rally? (Zacks) +14.29%
04:42AM	Zacks.com featured highlights Yext, Agenus and NCR Voyix (Zacks)
Jul-09-25 12:26PM	PROK Surges More Than 500% on Upbeat Data From Kidney Cell Therapy Study (Zacks) +6.58%
Jul-08-25 03:00PM	3 Top Earnings Acceleration Stocks to Buy for 2H25 (Zacks) -6.18%
Jul-07-25 08:55AM	Agenus' BOT/BAL Achieves 42% Two-Year Survival in Refractory MSS CRC, Advances Toward Registration with FDA Alignment on Phase 3 (Business Wire) -14.66%
Jul-02-25 10:32AM	Apellis Stock Rises on $300M Royalty Deal With Sobi for Aspaveli (Zacks) +13.84%
Jul-01-25 10:50AM	Biogen Begins Phase III Felzartamab Study for Third Kidney Disease (Zacks) +5.91%
09:17AM	Moderna Stock Gains on Encouraging Flu Vaccine Data (Zacks)
Jun-30-25 11:40AM	RARE's GTX-102 Gets FDA's Breakthrough Status for Angelman Syndrome (Zacks)
Jun-27-25 09:40AM	Are Medical Stocks Lagging CVS Health (CVS) This Year? (Zacks)
Jun-25-25 11:17AM	KRYS Up 4% on Initiating Dosing in Rare Eye Disease Phase III Study (Zacks)
11:06AM	Amarin Soars 27% on Vazkepa Licensing Deal With Recordati in the EU (Zacks)
10:02AM	Sanofi's Experimental Transplant Rejection Drug Gets FDA Orphan Tag (Zacks)
Jun-24-25 11:58AM	CHMP Backs NVO's Ozempic EU Label Update for Cardiovascular Indication (Zacks)
09:04AM	FDA Grants Label Expansion to AstraZeneca's Datroway in Lung Cancer (Zacks)
Jun-23-25 09:15AM	J&J's Drugs Get CHMP Recommendations for Blood Cancer Indications (Zacks)
Jun-19-25 09:55AM	After Golden Cross, Agenus (AGEN)'s Technical Outlook is Bright (Zacks)
Jun-17-25 12:02PM	Teva Partners With Fosun to Develop TEV-56278 Immuno-Cancer Therapy (Zacks) -7.00%
10:30AM	AbbVie's Venclexta Misses Goal in Myelodysplastic Syndromes Study (Zacks)
07:30AM	Agenus and Noetik Enter Collaboration to Develop AI-Enabled Predictive Biomarkers for BOT/BAL Using Foundation Models of Virtual Cell Biology (Business Wire)
Jun-16-25 03:01PM	Agenus Inc. (AGEN) Surges After Zydus Agreement, Analysts Upbeat on Stock (Insider Monkey) +9.36%

Agenus, Inc. is a clinical-stage company, which engages in the development and commercialization of technologies to treat cancers and infectious diseases. Its product pipeline includes Balstilimab, Zalifrelimab, AGEN1181, AGEN1327, AGEN2373, AGENt-797 and AGEN1777. The company was founded by Garo H. Armen and Pramod K. Srivastava on March 31, 1994 and is headquartered in Lexington, MA.

FounderDr. Garo H. Armen Ph.D.

Ph.D.Dr. Steven J. O'Day M.D.

Director and President & CEO of MiNK TherapeuticsDr. Jennifer S. Buell Ph.D.

Chief Information OfficerCraig Winter

Vice President of Investor Relations & Corporate DevelopmentMr. Zack Armen

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Agenus Inc.	Owner	Aug 29 '25	Proposed Sale	15.98	786,750	12,572,265		Aug 29 05:02 PM

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AGEN

Agenus Inc

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