OBIO

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Index	RUT
Market Cap	365.14M
Enterprise Value	336.04M
Income	-59.57M
Sales	31.98M
Book/sh	0.32
Cash/sh	1.83
Dividend Est.	-
Dividend TTM	-
Dividend Ex-Date	-
Dividend Gr. 3/5Y	- -
Payout	-
Employees	86
IPO	Aug 04, 2020

P/E	-
Forward P/E	-
PEG	-
P/S	11.42
P/B	18.90
P/C	3.32
P/FCF	-
EV/EBITDA	-
EV/Sales	10.51
Quick Ratio	8.24
Current Ratio	8.26
Debt/Eq	2.41
LT Debt/Eq	2.38
Option/Short	Yes / Yes

EPS (ttm)	-1.00
EPS next Y	-1.51
EPS next Q	-0.40
EPS this Y	-36.61%
EPS next Y	0.68%
EPS next 5Y	4.97%
EPS past 3/5Y	20.91% -164.92%
Sales past 3/5Y	111.62% -
EPS Y/Y TTM	45.31%
Sales Y/Y TTM	986.14%
EPS Q/Q	25.18%
Sales Q/Q	-89.47%
Earnings	Aug 10 AMC
EPS/Sales Surpr.	3.06% -36.09%

Insider Own	31.12%
Insider Trans	-0.04%
Inst Own	46.07%
Inst Trans	7.29%
ROA	-74.47%
ROE	-397.30%
ROIC	-59.40%
Gross Margin	98.64%
Oper. Margin	-181.36%
Profit Margin	-186.30%
SMA20	5.21%
SMA50	6.46%
SMA200	33.96%
Trades

Shs Outstand	60.11M
Shs Float	41.40M
Short Float	6.17%
Short Ratio	7.67
Short Interest	2.55M
52W High	6.50 -6.54%
52W Low	3.46 75.58%
Volatility	4.42% 6.00%
ATR (14)	0.32
RSI (14)	57.90
Beta	0.54
Rel Volume	0.25
Avg Volume	332.89K
Volume	25,516

Perf Week	8.68%
Perf Month	-4.33%
Perf Quarter	47.45%
Perf Half Y	53.03%
Perf YTD	46.39%
Perf Year	51.50%
Perf 3Y	31.50%
Perf 5Y	-38.39%
Perf 10Y	-
Recom	1.00
Target Price	12.43
Prev Close	6.09
Price	6.08
Change %	-0.24%

Consensus

Strong Buy

Avg. Price Target

$12.43

Implied Upside

+104.6%

Analysts8incl. previous ratings

Rating Distribution8 Buy · 0 Hold · 0 Sell

Date	Action	Analyst	Rating Change	Price Target Change	Implied Upside
Sep 10, 2026	Upgrade	BBTIG Research	Neutral → Buy	$10	+64.6%
Dec 10, 2025	Initiated	TTD Cowen	Buy	$15	+146.9%
Aug 20, 2025	Downgrade	BBTIG Research	Buy → Neutral
Mar 20, 2025	Initiated	BBTIG Research	Buy	$12	+97.5%
Jan 02, 2025	Initiated	BBarclays	Overweight	$16	+163.4%
Aug 22, 2024	Initiated	HH.C. Wainwright	Buy	$14	+130.4%
Jul 25, 2024	Initiated	RB. Riley Securities	Buy	$15	+146.9%
Jan 19, 2024	Initiated	JJefferies	Buy	$14	+130.4%
Feb 24, 2023	Initiated	PPiper Sandler	Overweight	$15	+146.9%
Feb 07, 2023	Initiated	CChardan Capital Markets	Buy	$20	+229.2%

Oct-29-26 08:30AM	Orchestra BioMed Announces Virtue SAB Presentation at TCT 2026 (GlobeNewswire)
Oct-22-26 08:30AM	Orchestra BioMed to Host R&D Day Featuring Clinical Insights and Development Plans for AVIM Therapy and Virtue SAB (GlobeNewswire) -5.77%
Oct-20-26 02:35PM	OpenAI acquires Orchestra Bio to boost drug development AI, Axios reports (Investing.com)
Oct-01-26 08:00AM	Orchestra BioMed Exceeds Full Enrollment Target in the BACKBEAT Global Pivotal Trial of AVIM Therapy (GlobeNewswire)
Sep-16-26 08:30AM	Orchestra BioMed Announces AVIM Therapy to Be Featured in Two Sessions at HRX Live 2026 (GlobeNewswire)
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Sep-15-26 08:30AM	Orchestra BioMed Receives $6.1 Million Milestone Payment from Acquisition of Vivasure by Haemonetics (GlobeNewswire)
Sep-02-26 04:05PM	Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Aug-27-26 08:30AM	Orchestra BioMed to Participate in the H.C. Wainwright 28th Annual Global Investment Conference (GlobeNewswire)
Aug-20-26 08:30AM	Orchestra BioMed to Participate in the Wells Fargo 21st Annual Healthcare Conference (GlobeNewswire)
Aug-10-26 04:12PM	Orchestra BioMed Reports Second Quarter 2026 Financial Results and Highlights Recent Business Updates (GlobeNewswire) +5.19%
Jun-29-26 08:00AM	Orchestra BioMed Joins Russell 3000 and Russell 2000 Indexes (GlobeNewswire) +12.03%
Jun-16-26 10:00AM	Sidoti Events, LLC's June Small-Cap Virtual Conference (ACCESSWIRE)
Jun-02-26 04:05PM	Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
May-19-26 08:30AM	Orchestra BioMed to Participate in the Jefferies Global Healthcare Conference (GlobeNewswire)
May-12-26 04:18PM	Orchestra BioMed Reports First Quarter 2026 Financial Results and Highlights Recent Business Updates (GlobeNewswire)
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08:30AM	Orchestra BioMed Targeting BACKBEAT Trial Enrollment Completion By End of Q3 2026 and Data Presentation in Q2 2027 (GlobeNewswire)
May-06-26 08:01AM	Orchestra BioMed Receives $15 Million Investment from Ligand Under Previously Announced Strategic Financing Agreement (GlobeNewswire)
08:00AM	Orchestra BioMed Receives $20 Million Payment from Medtronic Under Previously Announced Financing Agreement (GlobeNewswire)
Apr-30-26 09:00AM	FDA Grants Orchestra BioMed Additional Breakthrough Device Designation for AVIM Therapy (GlobeNewswire) +5.00%
Apr-23-26 12:00PM	Orchestra BioMed to Present AVIM Therapy Clinical and Mechanistic Data at HRS 2026 (GlobeNewswire)
Mar-12-26 08:17AM	Orchestra BioMed Reports Full Year 2025 Financial Results and Provides Fourth Quarter Business Update (GlobeNewswire)
Mar-03-26 08:00AM	Orchestra BioMed Announces Presentations Highlighting AVIM Therapy Potential Impact on Hypertensive Heart Disease and Heart Failure at THT and CRT (GlobeNewswire)
Feb-19-26 08:00AM	Orchestra BioMed to Participate in Upcoming Institutional Investor Conferences (GlobeNewswire)
Feb-13-26 04:05PM	Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Jan-12-26 09:00AM	Orchestra BioMed to Receive Up to $21 Million in Proceeds from Acquisition of Vivasure by Haemonetics (GlobeNewswire)
Dec-31-25 11:13AM	TD Cowen Initiates Orchestra BioMed (OBIO), Cites High-Margin Potential in Lead Cardiovascular Programs (Insider Monkey)
Dec-08-25 07:00AM	Orchestra BioMed Announces AVIM Therapy and Virtue SAB Program Presentations at ICI Meeting (GlobeNewswire)
Nov-29-25 01:25AM	Analyst Confidence in Orchestra BioMed Holdings (OBIO) High Amid Key Clinical and Strategic Advancements (Insider Monkey)
Nov-26-25 04:05PM	Orchestra BioMed Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Nov-11-25 09:00AM	Orchestra BioMed to Participate in Upcoming Institutional Investor Conferences (GlobeNewswire) +8.47%
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07:31AM	What To Expect From Orchestra BioMed Holdings Inc (OBIO) Q3 2025 Earnings (GuruFocus.com)
Nov-10-25 05:30PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q3 Loss, Beats Revenue Estimates (Zacks)
04:10PM	Orchestra BioMed Reports Third Quarter 2025 Financial Results and Highlights Recent Business Updates (GlobeNewswire)
08:40AM	ADC Therapeutics SA (ADCT) Reports Q3 Loss, Tops Revenue Estimates (Zacks)
Nov-04-25 10:00AM	Orchestra BioMed Holdings, Inc. (OBIO) Expected to Beat Earnings Estimates: Can the Stock Move Higher? (Zacks) -5.32%
Nov-03-25 08:00AM	Orchestra BioMed to Host Business Update Call on November 12, 2025 (GlobeNewswire)
Oct-28-25 08:00AM	Orchestra BioMed and Terumo Enter into New $30 Million Virtue SAB Strategic Agreements (GlobeNewswire)
Oct-27-25 09:00AM	Orchestra BioMed Announces First Patients Enrolled in Virtue SAB US Pivotal IDE Coronary Trial (GlobeNewswire)
Oct-09-25 08:00AM	Orchestra BioMed to Showcase Transformative Potential of AVIM Therapy in Keynote Presentation on Hypertensive Heart Disease at Georgia Innovation Summit (GlobeNewswire)
Sep-04-25 05:00PM	Orchestra BioMed Presents New AVIM Therapy Clinical Data at HRX Demonstrating Substantial and Sustained Blood Pressure Reductions that are Reproducible Upon Reactivation Following Washout (GlobeNewswire)
Aug-26-25 07:30AM	Orchestra BioMed Announces Publication of Clinical Data Demonstrating Favorable Blood Pressure and Hemodynamic Effects of AVIM Therapy in JACC: Clinical Electrophysiology (GlobeNewswire) +15.38%
Aug-14-25 08:00AM	Orchestra BioMed Announces Publication of AVIM Therapy Clinical Data in JACC: Advances Demonstrating Potential to Improve Cardiac Function in Patients with Hypertension and Diastolic Dysfunction (GlobeNewswire)
Aug-13-25 08:00AM	Campbellford Memorial Hospitals New Homecare Program Frees up 14.5 Hospital Bed-Days Per Patient Through a Partnership With Gotcare and OBIO® (Business Wire)
Aug-12-25 03:00PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q2 Loss, Beats Revenue Estimates (Zacks) +7.94%
08:14AM	Orchestra BioMed Reports Second Quarter 2025 Financial Results and Highlights Recent Business Updates (GlobeNewswire)
Aug-08-25 07:00AM	Orchestra BioMed Announces Rollout of FDA-Approved BACKBEAT Global Pivotal Study Protocol Update Significantly Expanding Patient Eligibility (GlobeNewswire)
Aug-05-25 07:00AM	Orchestra BioMed Secures Over $111 Million in Proceeds and Committed Capital Following Completion of Strategic Transactions and Concurrent Public and Private Equity Offerings (GlobeNewswire)
Aug-04-25 05:55PM	CRISPR Therapeutics AG (CRSP) Reports Q2 Loss, Lags Revenue Estimates (Zacks) +9.84%
Aug-01-25 07:59AM	Orchestra BioMed Announces Pricing of $40 Million Public Offering (GlobeNewswire) -20.26%
Jul-31-25 04:02PM	Orchestra BioMed Announces Proposed Public Offering (GlobeNewswire)
04:01PM	Ligand and Medtronic Commit $70 Million in Strategic Capital to Orchestra BioMed (GlobeNewswire)
Jul-16-25 08:00AM	OBIO® Paves the Way for Companies to Succeed in Canada as a Stepping Stone to New Global Markets (Business Wire) +7.88%
Jun-18-25 09:30AM	Orchestra BioMed Showcases AVIM Therapy as Purpose-Built Solution for Hypertensive Heart Disease at CSI Frankfurt 2025 (GlobeNewswire) -11.01%
May-20-25 08:00AM	Sidoti Events, LLC's Virtual May Micro-Cap Conference (ACCESSWIRE)
May-12-25 05:40PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q1 Loss, Tops Revenue Estimates (Zacks) +10.94%
04:28PM	Orchestra BioMed Reports First Quarter 2025 Financial Results and Highlights Recent Regulatory and Clinical Milestones (GlobeNewswire)
May-07-25 08:30AM	Orchestra BioMed's AVIM Therapy Global Intellectual Property Estate Reaches 137 Issued Patents for the Treatment of Hypertension and Heart Failure (GlobeNewswire)
May-06-25 05:10PM	Ultragenyx (RARE) Reports Q1 Loss, Misses Revenue Estimates (Zacks) -5.47%
May-05-25 10:00AM	Orchestra BioMed Holdings, Inc. (OBIO) Expected to Beat Earnings Estimates: Can the Stock Move Higher? (Zacks) -6.57%
Apr-29-25 09:00AM	Orchestra BioMed Receives FDA Approval of IDE to Initiate U.S. Coronary Pivotal Trial Randomizing First-in-Class Sirolimus-AngioInfusion Balloon, Virtue SAB, Head-to-Head with Paclitaxel-Coated Balloon (GlobeNewswire)
Apr-28-25 04:30PM	Orchestra BioMed to Participate in Upcoming Institutional Investor Conferences (GlobeNewswire) -6.12%
Apr-23-25 09:00AM	Orchestra BioMed Announces AVIM Therapy-Focused Satellite Symposium at HRS 2025 Annual Meeting (GlobeNewswire)
Apr-22-25 07:00AM	Orchestra BioMed Receives FDA Breakthrough Device Designation for AVIM Therapy (GlobeNewswire)
Mar-31-25 07:05PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q4 Loss, Lags Revenue Estimates (Zacks) -24.30%
04:21PM	Orchestra BioMed Reports Full Year 2024 Financial Results and Provides a Fourth Quarter Business Update (GlobeNewswire)
Mar-24-25 09:10AM	Clene Inc. (CLNN) Reports Q4 Loss, Lags Revenue Estimates (Zacks)
Feb-20-25 08:00AM	Orchestra BioMed to Present at Upcoming Investor Conferences (GlobeNewswire) -8.77%
Feb-18-25 08:00AM	Orchestra BioMed Appoints Vivek Reddy, M.D. as Executive Chairman of the BACKBEAT Study Steering Committee and Chairman of Bioelectronic Therapies Scientific Advisory Board (GlobeNewswire)
Feb-12-25 10:43AM	Orchestra BioMed Announces Data Demonstrating Favorable Impact of AVIM Therapy on Diastolic Dysfunction, a Key Driver of Heart Failure Progression, will be Presented as Late-Breaking Science at the THT 2025 Conference (GlobeNewswire)
Feb-05-25 08:00AM	Orchestra BioMed Announces Appointment of Former Medtronic SVP of Corporate Development Christopher Cleary to Board of Directors (GlobeNewswire)
Dec-09-24 07:00AM	Orchestra BioMed Announces AVIM Therapy Program Presentations at ICI Meeting (GlobeNewswire) +9.54%
Nov-26-24 04:05PM	Orchestra BioMed to Participate in the Piper Sandler 36th Annual Healthcare Conference (GlobeNewswire)
Nov-12-24 06:05PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q3 Loss, Tops Revenue Estimates (Zacks) -7.67% +7.24%
04:12PM	Orchestra BioMed Reports Third Quarter 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Nov-07-24 08:00AM	Orchestra BioMed to Participate in Jefferies London Healthcare Conference (GlobeNewswire) -5.50%
Aug-12-24 05:35PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q2 Loss, Lags Revenue Estimates (Zacks)
04:20PM	Orchestra BioMed Reports Second Quarter 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Aug-08-24 09:35AM	Orchestra BioMed Holdings, Inc. (OBIO) Loses -25.35% in 4 Weeks, Here's Why a Trend Reversal May be Around the Corner (Zacks) +13.55%
Aug-01-24 10:01AM	Orchestra BioMed Holdings, Inc. (OBIO) Expected to Beat Earnings Estimates: Should You Buy? (Zacks) -7.18%
Jul-30-24 08:00AM	Orchestra BioMed Announces Appointment of Cardiovascular Device Industry Expert John Mack to Board of Directors (GlobeNewswire)
Jul-26-24 12:00PM	Orchestra BioMed Holdings, Inc. (OBIO) Upgraded to Buy: Here's What You Should Know (Zacks) -6.70%
09:55AM	Wall Street Analysts Believe Orchestra BioMed Holdings, Inc. (OBIO) Could Rally 102.61%: Here's is How to Trade (Zacks)
Jul-23-24 09:00AM	Precision Neuroscience Expands Executive Team as Brain Computer Interface Industry Rapidly Advances (GlobeNewswire)
Jun-24-24 08:07AM	Orchestra BioMed Holdings, Inc. (OBIO) Stock Jumps 7.3%: Will It Continue to Soar? (Zacks) +9.02%
Jun-04-24 08:00AM	Orchestra BioMed Announces Further Details on In-Person R&D Day in New York Featuring Key Opinion Leaders to Discuss AVIM Therapy Program in Hypertensive Pacemaker Patients on June 11, 2024 (GlobeNewswire) +10.64%
Jun-03-24 12:00PM	All You Need to Know About Orchestra BioMed Holdings, Inc. (OBIO) Rating Upgrade to Buy (Zacks)
09:55AM	Does Orchestra BioMed Holdings, Inc. (OBIO) Have the Potential to Rally 135.64% as Wall Street Analysts Expect? (Zacks)
May-22-24 08:43AM	Orchestra BioMed to Participate in Jefferies Global Healthcare Conference (GlobeNewswire)
May-13-24 09:53PM	OBIO Stock Earnings: Orchestra BioMed Hldgs Beats EPS, Misses Revenue for Q1 2024 (InvestorPlace) +13.04%
06:05PM	Orchestra BioMed Holdings, Inc. (OBIO) Reports Q1 Loss, Misses Revenue Estimates (Zacks)
04:58PM	Orchestra BioMed Reports First Quarter 2024 Financial Results and Provides a Business Update (GlobeNewswire)
Apr-30-24 08:30AM	Orchestra BioMed Announces AVIM Therapy Global Intellectual Property Estate Reaches 110 Issued Patents (GlobeNewswire)
08:00AM	Orchestra BioMed to Host In-Person R&D Day in New York on AVIM Therapy Program in Hypertensive Pacemaker Patients on June 11, 2024 (GlobeNewswire)
Mar-27-24 04:17PM	Orchestra BioMed Reports Full Year 2023 Financial Results and Provides Fourth Quarter Business Update (GlobeNewswire)
Mar-26-24 08:00AM	Orchestra BioMed Announces Appointment of Medical Device Industry Expert David Pacitti to Board of Directors (GlobeNewswire) +5.20%
Mar-13-24 08:00AM	Orchestra BioMed Demonstrates Strength of Cardiovascular Pipeline with Virtue SAB and AVIM Therapy Presentations at CRT 2024 Annual Meeting (GlobeNewswire)
Mar-07-24 08:00AM	Orchestra BioMed to Participate in Upcoming Investor Conferences (GlobeNewswire) -6.62%
Mar-06-24 08:37AM	Orchestra BioMed Announces Presentation of Results from Clinical Study Demonstrating Favorable Hemodynamic Effects of AVIM Therapy In Hypertensive Pacemaker Patients (GlobeNewswire)
Feb-26-24 08:00AM	Orchestra BioMed Presents New Data Showing Sustained Clinically Meaningful Reduction in 24-Hour Ambulatory Systolic Blood Pressure in Hypertensive Pacemaker Patients Treated with AVIM Therapy for Over 3 Years (GlobeNewswire)
Feb-16-24 09:13AM	Why Orchestra BioMed (OBIO) Might Surprise This Earnings Season (Zacks) -8.45%

Show Previous News

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Sherman Darren	See Remarks	Oct 01 '26	Sale	6.36	15,000	95,400	1,119,402	Oct 02 04:30 PM
Sherman Darren	Officer	Oct 01 '26	Proposed Sale	6.27	15,000	94,050		Oct 01 10:37 AM
Hochman David P	See Remarks	Sep 03 '26	Buy	4.79	10,000	47,900	1,070,746	Sep 08 08:15 AM
Sherman Darren	See Remarks	Sep 01 '26	Sale	4.94	15,000	74,100	1,134,402	Sep 02 04:15 PM
Sherman Darren	Officer	Sep 01 '26	Proposed Sale	5.02	15,000	75,300		Sep 01 11:59 AM
Sherman Darren	See Remarks	Aug 26 '26	Buy	5.33	2,000	10,660	2,000	Aug 28 04:15 PM
Sherman Darren	See Remarks	Aug 03 '26	Sale	4.09	15,000	61,350	1,154,327	Aug 04 04:49 PM
Sherman Darren	Officer	Aug 03 '26	Proposed Sale	4.09	15,000	61,292		Aug 03 04:34 PM
Sherman Darren	Officer	Jul 01 '26	Proposed Sale	4.32	15,000	64,800		Jul 01 11:44 AM
Hochman David P	See Remarks	Jun 01 '26	Buy	3.83	5,000	19,150	1,064,029	Jun 02 04:28 PM
Sherman Darren	See Remarks	Jun 01 '26	Sale	3.87	15,000	58,050	1,184,327	Jun 02 04:27 PM
Sherman Darren	Officer	Jun 01 '26	Proposed Sale	3.87	15,000	58,050		Jun 01 04:16 PM
Aryeh Jason	Director	May 18 '26	Buy	3.75	665	2,494	118,118	May 20 08:00 AM
Aryeh Jason	Director	May 15 '26	Buy	3.90	8,971	34,987	117,453	May 19 08:00 AM
Hochman David P	See Remarks	May 15 '26	Buy	3.77	5,000	18,850	1,059,029	May 19 08:00 AM
Fain Eric S	Director	May 14 '26	Buy	4.13	20,000	82,600	91,709	May 18 08:00 AM
RTW INVESTMENTS, LP	10% Owner	Apr 27 '26	Sale	4.13	32	132	9,556,063	Apr 29 05:36 PM
Hochman David P	See Remarks	Mar 13 '26	Buy	4.29	10,000	42,900	1,086,467	Mar 16 04:54 PM
Hochman David P	See Remarks	Nov 14 '25	Buy	4.07	5,000	20,350	612,822	Nov 17 05:00 PM

Orchestra Biomed Holdings, Inc. engages in the provision of biomedical technologies to patients through risk-reward-sharing partnerships with medical device companies. The company was founded by David P. Hochman on May 25, 2020 and is headquartered in New Hope, PA.

FounderMr. David P. Hochman

FounderMr. Darren R. Sherman

Chief Financial OfficerMr. Andrew Lawrence Taylor M.B.A.

Executive Vice President of Corporate Development & StrategyMr. William Reed Little

Vice President of Human ResourcesMs. Lisa Daniels

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Orchestra BioMed Holdings Inc

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