SMMT

Summit Therapeutics Inc

14.32

Jun 29 • 04:00PM ET +0.31 (2.21%)

Healthcare Biotechnology USA Large NASD

Peers: EXEL MRNA REGN VRTX BMRN INCY IONS ALNY GILD AMGN

| Held by: XBI VTI VB VXF VBR IBB IWP IWR IWF VHT

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Index	-
Market Cap	11.11B
Enterprise Value	10.54B
Income	-1.21B
Sales	0.00M
Book/sh	0.70
Cash/sh	0.77
Dividend Est.	-
Dividend TTM	-
Dividend Ex-Date	-
Dividend Gr. 3/5Y	- -
Payout	-
Employees	265
IPO	Mar 05, 2015

P/E	-
Forward P/E	-
PEG	-
P/S	-
P/B	20.36
P/C	18.55
P/FCF	-
EV/EBITDA	-
EV/Sales	-
Quick Ratio	7.41
Current Ratio	7.41
Debt/Eq	0.04
LT Debt/Eq	0.03
Option/Short	Yes / Yes

EPS (ttm)	-1.60
EPS next Y	-1.11
EPS next Q	-0.27
EPS this Y	24.45%
EPS next Y	-1.67%
EPS next 5Y	29.98%
EPS past 3/5Y	-52.45% -13.76%
Sales past 3/5Y	- -
EPS Y/Y TTM	-384.68%
Sales Y/Y TTM	-
EPS Q/Q	-186.74%
Sales Q/Q	-
Earnings	Apr 30 AMC
EPS/Sales Surpr.	10.85% -100.00%

Insider Own	83.15%
Insider Trans	1.23%
Inst Own	15.54%
Inst Trans	1.28%
ROA	-233.81%
ROE	-270.95%
ROIC	-214.31%
Gross Margin	-
Oper. Margin	-
Profit Margin	-
SMA20	0.52%
SMA50	-17.17%
SMA200	-19.28%
Trades

Shs Outstand	776.02M
Shs Float	130.76M
Short Float	28.15%
Short Ratio	7.02
Short Interest	36.81M
52W High	30.98 -53.78%
52W Low	12.55 14.10%
Volatility	3.96% 6.22%
ATR (14)	0.92
RSI (14)	43.00
Beta	-1.24
Rel Volume	1.15
Avg Volume	5.25M
Volume	5,976,842

Perf Week	0.28%
Perf Month	-17.75%
Perf Quarter	-13.63%
Perf Half Y	-22.09%
Perf YTD	-18.12%
Perf Year	-30.49%
Perf 3Y	470.52%
Perf 5Y	92.73%
Perf 10Y	77.01%
Recom	1.69
Target Price	29.84
Prev Close	14.01
Price	14.32
Change	2.21%

Date	Action	Analyst	Rating Change	Price Target Change
May-22-26	Downgrade	H.C. Wainwright	Buy → Neutral
Apr-08-26	Initiated	Stifel	Buy	$45
Mar-16-26	Downgrade	Jefferies	Buy → Hold	$15
Dec-17-25	Upgrade	Barclays	Underweight → Equal Weight	$18
Nov-18-25	Initiated	Wolfe Research	Peer Perform
Sep-17-25	Initiated	Barclays	Underweight	$13
Sep-04-25	Initiated	Guggenheim	Buy	$40
Aug-19-25	Initiated	Piper Sandler	Neutral	$21
Jul-01-25	Initiated	UBS	Buy	$30
Jun-11-25	Initiated	Leerink Partners	Underperform	$12
Mar-26-25	Upgrade	Citigroup	Neutral → Buy	$23 → $35
Mar-21-25	Initiated	Cantor Fitzgerald	Overweight
Mar-12-25	Initiated	Evercore ISI	Outperform	$30
Feb-28-25	Initiated	Goldman	Buy	$42
Jan-08-25	Initiated	Truist	Buy	$35
Dec-11-24	Initiated	Wells Fargo	Overweight	$30
Dec-06-24	Initiated	Jefferies	Buy	$31
Nov-04-24	Initiated	JMP Securities	Mkt Outperform	$32
Sep-27-24	Downgrade	Citigroup	Buy → Neutral	$19 → $23
Aug-12-24	Initiated	H.C. Wainwright	Buy	$16

Show Previous Ratings

Jun-23-26 10:19AM	Summit Therapeutics finance chief tops list of public CFO pay in 2025 (CFO.com)
Jun-10-26 07:19AM	Why Is SMMT Stock Tumbling Today? (Stocktwits) -8.68%
Jun-09-26 04:47PM	Summit Therapeutics Announces Proposed Public Offering of Common Stock (Business Wire)
Jun-04-26 04:30PM	Summit Therapeutics to Participate in the 47th Annual Goldman Sachs Global Healthcare Conference (Business Wire)
04:55AM	Pharma is betting big on PD-1/VEGF bispecifics. But are companies chasing the wrong target? (Pharma Voice)
08:44PM	Loading…
Jun-02-26 08:44PM	ASCO26: Bispecific antibody and RET fusion-targeting assets garner attention in NSCLC (Pharmaceutical Technology) -5.41%
Jun-01-26 08:06AM	An experimental lung-cancer drug could replace Keytruda one day. But investors aren't wowed. (MarketWatch) -10.43%
12:25AM	SMMT Stock Surges Overnight: Cancer Drug Survival Win Raises The Bar As PFE, BMY, MRK Chase Keytruda's Successor (Stocktwits)
May-31-26 09:06AM	Ivonescimab with Chemotherapy Demonstrated a Statistically Significant Overall Survival Benefit Compared to Tislelizumab Plus Chemotherapy in 1L Treatment of Patients with Squamous NSCLC in the HARMONi-6 Study Conducted by Akeso in China (Business Wire)
May-30-26 08:00AM	Encouraging Global Phase II Ivonescimab Data in First-Line Metastatic Colorectal Cancer Presented at ASCO 2026 (Business Wire)
May-28-26 06:33PM	Akari Therapeutics Highlights 1st ASCO Abstract Acceptance (IPO-Edge.com)
12:53PM	VERAXA Biotech Secures $27.5M Financing, to Go Public Via SPAC (Exec Edge)
May-22-26 09:38AM	Texas Instruments, Generac upgraded: Wall Street's top analyst calls (The Fly)
07:46AM	ASCO26: 5 data snapshots ahead of the years biggest cancer drug meeting (BioPharma Dive)
May-18-26 02:22PM	B7-H3 Becomes The Hottest Antigen In Oncology, And One NK Engager Enters Clinic (PR Newswire) -5.04%
08:28AM	Loading…
May-01-26 08:28AM	Summits self-inflicted stumble; Esperions take-private deal (BioPharma Dive) -24.91%
Apr-30-26 04:32PM	Summit Therapeutics Reports Financial Results and Operational Progress for the First Quarter Ended March 31, 2026 (Business Wire)
Mar-27-26 08:15AM	Multiple Ivonescimab Data Sets from Phase III Studies in Advanced NSCLC Patient Populations to be Featured at ELCC 2026 (Business Wire)
Mar-03-26 02:21AM	Summit Therapeutics (SMMT) Ends 2025 With Strong Cash Reserves and Increased Clinical Investment (Insider Monkey) -6.67%
Mar-02-26 02:56AM	Summit Therapeutics Inc. (SMMT) Focused on Non-Small Cell Lung Cancer Trial of Ivonescimab (Insider Monkey)
Feb-26-26 06:45PM	Summit Therapeutics to Present at Upcoming Investor Conferences (Business Wire)
09:38AM	RVMD Reports Wider-Than-Expected Q4 Loss, Issues 2026 Expense View (Zacks)
Feb-24-26 08:02PM	Summit Therapeutics Inc (SMMT) Q4 2025 Earnings Call Highlights: Strong Cash Position and ... (GuruFocus.com)
11:31AM	SMMT Incurs Wider-Than-Expected Q4 Loss, Pipeline Progress in Focus (Zacks)
08:30AM	Summit Therapeutics Inc. Q4 2025 Earnings Call Summary (Moby)
Feb-23-26 08:17PM	Summit Therapeutics Q4 Earnings Call Highlights (MarketBeat)
04:05PM	Summit Therapeutics Reports Financial Results and Operational Progress for the Fourth Quarter and Year Ended December 31, 2025 (Business Wire)
Feb-22-26 07:47AM	Nvidia earnings, SCOTUS tariff fallout, geopolitical tensions rise: What to watch this week (Yahoo Finance)
Feb-17-26 05:05PM	Summit Therapeutics to Host Fourth Quarter and Full Year 2025 Financial Results & Operational Progress Call on February 23, 2026 (Business Wire)
Feb-16-26 12:24PM	Summit Therapeutics (SMMT) Grabs Investor Attention After Major FDA Breakthrough (Insider Monkey)
10:49AM	Loading…
Feb-13-26 10:49AM	MRK Up More Than 7% on Improved Long-Term Prospects: Still a Sell? (Zacks)
Feb-12-26 06:54AM	Is Summit Therapeutics Inc. (SMMT) One of the Most Oversold NASDAQ Stocks to Invest In? (Insider Monkey)
Feb-06-26 08:00AM	China Biotech Lights Up. U.S. Stocks Prepare For A New Powerhouse. (Investor's Business Daily) +8.23%
Feb-05-26 07:22AM	FDA Accepts Summit Therapeutics' (SMMT) BLA For Ivonescimab In NSCLC With November 14 PDUFA Date Following Positive Phase III Data (Insider Monkey)
Jan-31-26 07:13PM	2 Stocks That Could Soar This Year (Motley Fool)
Jan-30-26 04:30PM	Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire) -5.97%
10:24AM	FDA Accepts SMMT's Application Seeking Approval for NSCLC Drug (Zacks)
07:50AM	Buy, Sell or Hold MRK Stock: Key Factors to Watch Before Q4 Earnings (Zacks)
Jan-29-26 12:28PM	FDA Accepts Summit's Lung Cancer Drug Application, Review Underway (Benzinga)
07:30AM	Summit Therapeutics Announces U.S. FDA Acceptance of Biologics License Application (BLA) Seeking Approval for Ivonescimab in Combination with Chemotherapy in Treatment of Patients with EGFRm NSCLC Post-TKI Therapy (Business Wire)
05:20AM	Moderna holds a garage sale; Roche defends obesity drug data (BioPharma Dive)
Jan-28-26 06:57AM	Encouraging Guidance on Clinical Program Makes Summit Therapeutics (SMMT) Look Attractive (Insider Monkey)
Jan-18-26 12:31PM	Trip.com, Regencell Bioscience, And Atlassian Are Among Top 10 Large Cap Losers Last Week (Jan. 12-Jan. 16): Are the Others in Your Portfolio? (Benzinga)
Jan-15-26 10:20PM	Akeso Confident of Cancer Drug's FDA Approval Odds (Bloomberg)
Jan-12-26 12:43PM	Gold, Silver Spike To Record Highs As Fed Independence Falters: What's Moving Markets Monday? (Benzinga) -13.41%
12:05PM	2 Biotech Stocks That Could Soar This Year (Motley Fool)
06:15AM	Summit Therapeutics Announces Clinical Trial Collaboration with GSK to Evaluate Ivonescimab in Combination with GSK's B7-H3 Antibody Drug Conjugate (ADC) (Business Wire)
06:00AM	Summit Therapeutics Announces Submission of Biologics License Application (BLA) to U.S. FDA Seeking Approval for Ivonescimab in Combination with Chemotherapy in 2L+ Treatment of Patients with EGFRm NSCLC (Business Wire)
Jan-09-26 08:16PM	Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Jan-06-26 07:30AM	Summit Therapeutics to Present at the 44th Annual J.P. Morgan Healthcare Conference (Business Wire) +7.00%
Jan-02-26 09:10AM	Cantor Fitzgerald Reaffirms Overweight Rating on Summit Therapeutics (SMMT) Before Key 2026 Catalyst (Insider Monkey)
Dec-29-25 01:53PM	Top Research Reports for Apple, Cisco & IBM (Zacks)
Dec-17-25 09:59AM	Pfizer Issues Soft 2026 View: What Does It Mean for the Stock's Future? (Zacks)
Dec-11-25 07:44AM	Citi Asserts Buy Rating on Summit Therapeutics Inc. (SMMT) on Pipeline Development (Insider Monkey)
Dec-09-25 05:25PM	2 Stocks Up Over 600% in the Past 3 Years With More Room to Run (Motley Fool) -8.62% +5.41%
11:04AM	MRK Stock Trading Above 200- & 50-Day SMA for 2 Months: Time to Buy? (Zacks)
Dec-05-25 04:30PM	Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
01:25PM	Trading Near Its 52-Week Low, Is Summit Therapeutics a Good Stock to Buy Right Now? (Motley Fool)
Dec-03-25 04:44AM	Don't Buy Summit Therapeutics Until This Big Thing Happen (Motley Fool) +6.49%
Dec-02-25 07:00AM	2 Monster Stocks in the Making to Buy and Hold (Motley Fool)
Nov-27-25 09:45AM	AstraZeneca or Merck: Which Oncology Giant Has the Edge? (Zacks)
Nov-17-25 08:05AM	MRK Up Nearly 10% in a Month: Should You Buy, Sell or Hold the Stock? (Zacks) -5.99%
Nov-10-25 08:19PM	Summit Therapeutics (SMMT) Reports Positive Results from the Phase III HARMONi Trial (Insider Monkey)
09:48AM	Will Keytruda Aid MRK's Growth in 2026 After a Subdued Q3? (Zacks)
Nov-07-25 09:00AM	Ivonescimab Plus Chemotherapy Demonstrates a Statistically Significant Benefit in Overall Survival with a Hazard Ratio of 0.74 in 2L+ Treatment of Patients with EGFRm NSCLC in HARMONi-A Study Conducted by Akeso in China (Business Wire)
Nov-04-25 07:00AM	Summit Therapeutics to Present at Upcoming Investor Conferences (Business Wire)
Oct-31-25 07:07AM	Insiders Are Snapping Up These 2 Stocks and Analysts Like What They See (TipRanks)
07:00AM	Overall Survival Data from HARMONi-A, Featuring Ivonescimab in Combination with Chemotherapy vs. Chemotherapy in 2L+ Treatment of Patients with EGFRm NSCLC in China, to be Showcased at SITC 2025 (Business Wire)
Oct-30-25 09:39PM	Summit Therapeutics (SMMT) Releases Financial Results and Updates on Operational Progress for Q3 2025 (Insider Monkey)
Oct-28-25 06:43PM	Why Wall Street Is Backing These 3 Comeback Stocks (MarketBeat)
03:21PM	Insiders Are Buying These 3 Stocks Hand Over Fist (24/7 Wall St.)
12:37PM	Buy, Sell or Hold MRK Stock Ahead of Q3 Earnings? Things to Know (Zacks)
Oct-27-25 05:51AM	1 Monster Stock in the Making to Buy and Hold (Motley Fool)
Oct-25-25 09:45AM	Insiders Are Scooping Up Shares of a Miner, a Driller, and a Biotech (24/7 Wall St.)
Oct-24-25 07:00PM	Summit Therapeutics: A Risky Bet in the Biotech Arena? (Motley Fool)
04:58AM	Chugai buys a kidney biotech; ICER targets rising launch prices (BioPharma Dive)
Oct-21-25 01:41PM	SMMT's Q3 Loss Wider Than Expected, Stock Down on Study Amendments (Zacks) -6.46%
09:24AM	Company News for Oct 21, 2025 (Zacks)
05:53AM	Summit Therapeutics (SMMT) Expands its Phase 3 Trials for Ivonescimab (Insider Monkey)
Oct-20-25 03:00PM	Summit Therapeutics Inc (SMMT) Q3 2025 Earnings Call Highlights: Promising Clinical ... (GuruFocus.com)
06:45AM	Summit Therapeutics Reports Financial Results and Operational Progress for the Third Quarter and Nine Months Ended September 30, 2025 (Business Wire)
05:13AM	Summits dual-acting drug scores lung cancer win (BioPharma Dive)
Oct-19-25 10:30AM	Ivonescimab with Chemotherapy Reduced the Risk of Disease Progression or Death by 40% Compared to Tislelizumab (PD-1 Inhibitor) Plus Chemotherapy in 1L Treatment of Patients with Squamous NSCLC in the HARMONi-6 Study Conducted by Akeso in China (Business Wire)
07:33AM	Tesla, Netflix set to report earnings as US-China trade fight turns 'unsustainable': What to watch this week (Yahoo Finance)
Oct-17-25 07:00AM	Summit Therapeutics Announces Expansion of Ivonescimab Global Phase III Development Program with HARMONi-GI3 Study in 1L Colorectal Cancer (Business Wire)
Oct-15-25 07:00AM	Summit Therapeutics to Host ESMO Data Update & Third Quarter Earnings Call on October 20, 2025 (Business Wire)
Oct-08-25 12:57AM	Where is Summit Therapeutics (SMMT) Headed According to Analysts? (Insider Monkey)
Oct-07-25 08:27AM	Merck Rises 13% in a Week: Should You Buy, Sell or Hold the Stock? (Zacks)
Oct-05-25 09:45AM	1 Monster Stock in the Making to Buy and Hold (Motley Fool)
Oct-02-25 01:35AM	H.C. Wainwright Reaffirms Price Target for Summit Therapeutics (SMMT) After Ivonescimab Milestones (Insider Monkey)
Oct-01-25 01:39PM	Summit Therapeutics Inc. (SMMT) Highlights Ivonescimab Progress at WCLC 2025 (Insider Monkey)
Sep-24-25 04:30PM	Summit Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire) +7.05%
07:00AM	HARMONi-6, Featuring Ivonescimab Combined with Chemotherapy vs. Tislelizumab Plus Chemotherapy in 1L Treatment of Patients with Squamous NSCLC in China, to be Showcased in Presidential Symposium at ESMO 2025 (Business Wire)
Sep-22-25 10:21AM	Will the FDA's Nod for Subcutaneous Keytruda Ease Merck's Headwinds? (Zacks)
Sep-18-25 11:25PM	Jim Cramer on Summit Therapeutics: "We're Going to Have to Move On" (Insider Monkey) +6.30%
10:41AM	Summit Therapeutics Inc. (SMMT) Faces Volatile 2025 as Ivonescimab Gains Approval in China (Insider Monkey)
Sep-12-25 07:57PM	Lightning Round: Ring the register on Opendoor, don't be in a meme stock, says Jim Cramer (CNBC TV)
Sep-11-25 10:05AM	Merck Falls 14% YTD: Time to Buy, Sell or Hold the Stock? (Zacks) +5.65%
Sep-10-25 12:59AM	Guggenheim Initiates Summit Therapeutics (SMMT) With a Buy Rating (Insider Monkey) -6.48%
Sep-09-25 01:17PM	SMMT Stock Plummets 25% on Regional Data Differences in NSCLC Study (Zacks)

Summit Therapeutics, Inc. is a biopharmaceutical company, that focuses on the discovery, development, and commercialization of patient, physician, caregiver, and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. The firm conducts clinical programs focusing on Clostridioides Difficile Infection (CDI). Its lead product, Ridinilazole, is an orally administered small molecule antibiotic that is in Phase III clinical trials for the treatment of CDI. The company was founded in 2003 and is headquartered in Miami, FL.

Co-CEO & Executive ChairmanMr. Robert W. Duggan

M.B.A.Dr. Mahkam Zanganeh D.D.S.

FRS CBEProf. Kay Elizabeth Davies DBE

Chief Accounting OfficerMr. Bhaskar Anand

Senior Director of Investor RelationsMr. Nathan LiaBraaten

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Zanganeh Mahkam	Co-Chief Executive Officer	Jun 12 '26	Buy	13.12	3,810,000	49,987,200	573,883,879	Jun 12 02:35 PM
DUGGAN ROBERT W	Co-Chief Executive Officer	Jun 12 '26	Buy	13.12	3,810,000	49,987,200	573,883,879	Jun 12 12:28 PM
DUGGAN ROBERT W	Co-Chief Executive Officer	Jun 04 '26	Buy	14.60	100,000	1,460,000	25,824,474	Jun 04 06:08 PM
Zanganeh Mahkam	Co-Chief Executive Officer	Jun 04 '26	Buy	14.60	100,000	1,460,000	25,824,474	Jun 04 05:45 PM
Soni Manmeet Singh	COO and CFO	Jun 04 '26	Buy	14.45	50,000	722,250	3,123,603	Jun 04 04:40 PM
Xia Yu	Director	Oct 21 '25	Buy	18.74	533,617	9,999,983	32,057,147	Oct 23 09:06 PM
DUGGAN ROBERT W	Co-Chief Executive Officer	Oct 21 '25	Buy	18.74	26,680	499,983	76,680	Oct 23 04:08 PM
Zanganeh Mahkam	Co-Chief Executive Officer	Oct 21 '25	Buy	18.74	26,680	499,983	76,680	Oct 23 04:06 PM
Zanganeh Mahkam	Co-Chief Executive Officer	Sep 10 '25	Buy	17.68	333,394	5,894,406	556,088,090	Sep 11 07:36 PM
Zanganeh Mahkam	Co-Chief Executive Officer	Sep 11 '25	Buy	18.07	5,000	90,350	556,093,090	Sep 11 07:36 PM
DUGGAN ROBERT W	Co-Chief Executive Officer	Sep 10 '25	Buy	17.68	333,394	5,894,406	556,088,090	Sep 11 07:32 PM
DUGGAN ROBERT W	Co-Chief Executive Officer	Sep 11 '25	Buy	18.07	5,000	90,350	556,093,090	Sep 11 07:32 PM

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