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APVO

Aptevo Therapeutics Inc

Nov 12 • 04:00PM ET

1.48

-0.02 -1.33 %

Healthcare • Biotechnology • USA • NASD

Peers: JNJ PFE MRK LLY AMGN BMY GILD BIIB REGN VRTX

Index	-	P/E	-	EPS (ttm)	-185.07	Insider Own	0.00%	Shs Outstand	16.85M	Perf Week	3.50%
Market Cap	24.94M	Forward P/E	-	EPS next Y	-1.60	Insider Trans	-	Shs Float	16.85M	Perf Month	-9.20%
Enterprise Value	7.87M	PEG	-	EPS next Q	-0.45	Inst Own	6.13%	Short Float	2.97%	Perf Quarter	-27.45%
Income	-27.95M	P/S	-	EPS this Y	99.69%	Inst Trans	166.66%	Short Ratio	0.09	Perf Half Y	-77.58%
Sales	0.00M	P/B	1.18	EPS next Y	70.26%	ROA	-132.66%	Short Interest	0.50M	Perf YTD	-98.28%
Book/sh	1.26	P/C	1.18	EPS next 5Y	90.39%	ROE	-256.30%	52W High	298.00 -99.50%	Perf Year	-99.28%
Cash/sh	1.25	P/FCF	-	EPS past 3/5Y	79.32% 80.96%	ROIC	-130.73%	52W Low	1.32 12.12%	Perf 3Y	-100.00%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	- -	Gross Margin	-	Volatility	6.34% 5.65%	Perf 5Y	-100.00%
Dividend TTM	-	EV/Sales	-	EPS Y/Y TTM	99.02%	Oper. Margin	-	ATR (14)	0.11	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	4.03	Sales Y/Y TTM	-	Profit Margin	-	RSI (14)	47.01	Recom	1.00
Dividend Gr. 3/5Y	- -	Current Ratio	4.03	EPS Q/Q	99.38%	SMA20	-1.17%	Beta	1.41	Target Price	21.00
Payout	-	Debt/Eq	0.23	Sales Q/Q	-	SMA50	-4.07%	Rel Volume	0.07	Prev Close	1.50
Employees	42	LT Debt/Eq	0.23	Earnings	Nov 06 BMO	SMA200	-91.43%	Avg Volume	5.64M	Price	1.48
IPO	Jul 20, 2016	Option/Short	No / Yes	EPS/Sales Surpr.	0.00% -	Trades		Volume	392,335	Change	-1.33%

Date	Action	Analyst	Rating Change	Price Target Change
Nov-05-18	Initiated	Ladenburg Thalmann	Buy
Oct-05-17	Resumed	Piper Jaffray	Overweight	$6

Nov-10-25 08:05AM	Aptevo Debuts First Trispecific Antibody Candidate, APVO451, with Preclinical Data Demonstrating Immune Activation in Hard-to-Treat Solid Tumors (ACCESSWIRE) +6.12%
Nov-06-25 08:05AM	Aptevo Therapeutics Reports 3Q25 Financial Results And Provides A Business Update (ACCESSWIRE)
Oct-08-25 08:20AM	Aptevo Presenting Scientific and Clinical Updates at SITC and ASH, also Participating in Leading Financial and Industry Conferences in the Fourth Quarter (ACCESSWIRE)
Sep-16-25 08:30AM	Mipletamig Delivers 100% Remission Rate in Cohort 3 of RAINIER Trial for AML (ACCESSWIRE)
Sep-04-25 08:45AM	Aptevo Unveils Two Next-Generation, Industry Leading Trispecifics, Expanding CD3 Oncology Pipeline to Five Molecules (ACCESSWIRE)
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Aug-13-25 08:05AM	Aptevo Highlights APVO442, a CD3-Directed Preclinical Candidate for Prostate Cancer (ACCESSWIRE) -7.28%
Aug-11-25 08:05AM	Aptevo Therapeutics Reports 2Q25 Financial Results And Provides A Business Update (ACCESSWIRE)
Jul-15-25 04:57PM	Aptevo Meets Nasdaq $2.5M Equity Requirement (Insider Monkey)
Jun-21-25 09:00AM	Aptevo announces addition of preclinical candidate APVO455 to portfolio (TipRanks)
Jun-20-25 11:30AM	Aptevo Therapeutics Announces Closing of $8 Million Offering Priced At-the-Market Under Nasdaq Rules (ACCESSWIRE) -18.71%
08:55AM	Aptevo Expands Differentiated CD3 Portfolio with APVO455, Advancing a Suite of Targeted T-cell Engagers (ACCESSWIRE)
Jun-18-25 10:52AM	Aptevo Therapeutics Announces $8 Million Offering Priced At-the-Market Under Nasdaq Rules (ACCESSWIRE) +81.91%
08:01AM	Mipletamig Demonstrates Compelling Clinical Activity in Frontline AML (ACCESSWIRE)
Jun-13-25 08:05AM	Aptevo Participating in the BIO International Convention (ACCESSWIRE) -8.16%
May-22-25 08:05AM	Aptevo Therapeutics Announces 1-for-20 Reverse Stock Split as part of Nasdaq Compliance Plan (ACCESSWIRE) -21.05%
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May-15-25 08:05AM	Aptevo Therapeutics Reports 1Q25 Financial Results And Provides an Update on Mipletamig (ACCESSWIRE)
May-08-25 08:45AM	Aptevo Therapeutics Provides Program Update for Bispecific APVO711, a PD-L1 X CD40 that Combines a Checkpoint Inhibitor and Immune Activation (ACCESSWIRE) -7.69%
Apr-22-25 04:05PM	Aptevo Therapeutics Announces the Closing of $2.0 Million Registered Direct Offering Priced At-The-Market Under Nasdaq Rules (ACCESSWIRE) +9.08% +6.72%
Apr-21-25 02:40PM	Aptevo Therapeutics $2.0 Million Registered Direct Offering Priced At-The-Market Under Nasdaq Rules (ACCESSWIRE) -26.24%
Apr-04-25 04:05PM	Aptevo Therapeutics Announces the Closing of $2.1 Million Registered Direct Offering and Concurrent Private Placement Priced At-The-Market Under Nasdaq Rules (ACCESSWIRE) -25.13% -6.71%
Apr-03-25 08:50AM	Aptevo Therapeutics $2.1 Million Registered Direct Offering and Concurrent Private Placement Priced At-The-Market Under Nasdaq Rules (ACCESSWIRE) +44.20%
Mar-20-25 02:26PM	Aptevo Therapeutics Says Two Additional Patients In Early-Stage Leukemia Trial Achieve Remission Within 30 Days of Treatment (Benzinga) -6.09%
08:35AM	RAINIER Trial Data Update: Two Additional AML Patients Achieve Remission Within 30 Days of Treatment (ACCESSWIRE)
Mar-18-25 08:05AM	Aptevo Highlights APVO603: A Novel Bispecific Antibody Targeting 4-1BB and OX40 for Enhanced Solid Tumor Immunotherapy (ACCESSWIRE)
Mar-06-25 08:00AM	Aptevo to Participate in March Conferences (ACCESSWIRE)
Feb-15-25 06:59PM	Aptevo Therapeutics Interview to Air on the RedChip Small Stocks, Big Money(TM) Show on Bloomberg TV (ACCESS Newswire)
Feb-14-25 08:05AM	Aptevo Therapeutics Reports 2024 Financial Results And Provides A Business Update (ACCESSWIRE) -8.24%
Jan-15-25 08:00AM	Aptevo's Peter Pavlik, PhD, Chairing Session on 'Bi and Multispecific Biologics' at Cambridge Healthcare Institute's Pep Talk 2025 (ACCESSWIRE)
Dec-12-24 12:50PM	Aptevo Therapeutics Announces Exercise of Warrants for $6.2 Million Gross Proceeds (ACCESSWIRE) -43.76%
09:00AM	100% of Patients Achieve Remission Within 30 Days in Cohort 1 of Bispecific Mipletamig Frontline AML Trial (ACCESSWIRE)
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Dec-04-24 08:35AM	Bispecific Antibody, APVO442, Differentiated to Treat Prostate Cancer with Precision Tumor Targeting and Reduced Risk of Side Effects (ACCESSWIRE) +15.01%
Nov-29-24 09:55AM	Aptevo Therapeutics Announces 1-for 37 Reverse Stock Split As Part of Nasdaq Compliance Plan (ACCESSWIRE) -18.88%
Nov-26-24 08:35AM	Proving the Concept: Aptevo Technology, Pipeline, to Exemplify the Speed and Power of Modular Biotherapeutics at Presentation (ACCESSWIRE) +9.20%
Nov-22-24 08:35AM	Aptevo Highlights the Potential of the Company's Robust Portfolio in Cancer Immunotherapy, the Success of Bispecifics as a Category, and Their Growing Importance in the Oncology Treatment Paradigm (ACCESSWIRE) +15.33%
Nov-20-24 08:35AM	First Patient Dosed in Aptevo's Ongoing RAINIER Trial Achieves 90% Reduction in Leukemic Blasts Within the First 30 Days of Treatment, Continues Overall Efficacy Trend Seen in Prior Mipletamig AML Studies (ACCESSWIRE) +16.05%
Nov-11-24 08:15AM	First-in-Class Bispecific Antibody, ALG.APV-527, Meets Important Trial Endpoints in Phase 1 Solid Tumor Trial (ACCESSWIRE)
Nov-07-24 08:05AM	Aptevo Therapeutics Reports 3Q 2024 Financial Results and Provides a Business Update (ACCESSWIRE) +19.77%
Oct-29-24 08:05AM	Aptevo Therapeutics and Alligator Bioscience to Present Additional Positive Interim Phase 1 Data Evaluating ALG.APV-527 Monotherapy in Multiple Solid Tumor Types, at SITC 2024 (ACCESSWIRE) +27.95%
Sep-18-24 04:05PM	Aptevo Therapeutics Announces Closing of $3.0 Million Offering Priced At-the-Market Under Nasdaq Rules (ACCESSWIRE) -19.55% +6.93%
Sep-16-24 08:05PM	Aptevo Therapeutics Announces $3.0 Million Offering Priced At-the-Market Under Nasdaq Rules (ACCESSWIRE) -7.02% -38.00%
08:20AM	Alligator Bioscience and Aptevo Therapeutics Announce Data from Phase 1 ALG.APV-527 Monotherapy Trial Showing 60% of Evaluable Patients Achieved Stable Disease in Solid Tumor Study (ACCESSWIRE)
08:05AM	Aptevo Therapeutics and Alligator Bioscience Announce Data from Phase 1 ALG.APV-527 Monotherapy Trial Showing 60% of Evaluable Patients Achieved Stable Disease in Solid Tumor Study (ACCESSWIRE)
Sep-13-24 08:20AM	Alligator Bioscience and Aptevo Therapeutics to Present Positive Interim Phase 1 Data Evaluating ALG.APV-527 Monotherapy in Multiple Solid Tumor Types at ESMO Congress 2024 (ACCESSWIRE)
08:05AM	Aptevo Therapeutics and Alligator Bioscience to Present Positive Interim Phase 1 Data Evaluating ALG.APV-527 Monotherapy in Multiple Solid Tumor Types, at ESMO Congress 2024 (ACCESSWIRE)
Aug-13-24 08:05AM	Phase 1b/2 'RAINIER' Frontline Acute Myeloid Leukemia (AML) Trial Initiated (ACCESSWIRE) -8.57%
Aug-08-24 08:05AM	Aptevo Therapeutics Reports 2Q 2024 Financial Results and Provides a Business Update (ACCESSWIRE)
Jul-01-24 04:20PM	Aptevo Therapeutics Announces Closing of $2.75 Million Offering (ACCESSWIRE) +9.15% -10.78%
Jun-28-24 09:20AM	Aptevo Therapeutics Announces $2.75 Million Offering Priced At-the-Market Under Nasdaq Rules (ACCESSWIRE) -40.57%
Jun-17-24 07:40AM	Today's Biggest Pre-Market Stock Movers: 10 Top Gainers and Losers on Monday (InvestorPlace) -20.53%
Jun-03-24 08:05AM	Aptevo Participating in the BIO International Convention (ACCESSWIRE) +10.58%
May-14-24 08:05AM	Aptevo Therapeutics Presenting at The Protein & Antibody Engineering Summit, Boston, MA (ACCESSWIRE)
May-08-24 12:54PM	APVO Stock Earnings: Aptevo Therapeutics Beats EPS for Q1 2024 (InvestorPlace) -11.64%
08:05AM	Aptevo Therapeutics Reports 1Q 2024 Financial Results and Provides a Business Update (ACCESSWIRE)
May-02-24 07:37AM	Today's Biggest Pre-Market Stock Movers: 10 Top Gainers and Losers on Thursday (InvestorPlace) +17.71%
Apr-16-24 12:47PM	Aptevo (APVO) Stock Plummets 79% in a Week: Here's Why (Zacks)
Apr-15-24 04:05PM	Aptevo Therapeutics Announces Closing of $4.6 Million Public Offering (ACCESSWIRE) -7.35%
Apr-11-24 08:15AM	Why Is Aptevo Therapeutics (APVO) Stock Down 56% Today? (InvestorPlace) -60.08%
08:00AM	Aptevo Therapeutics Announces Pricing of $4.6 Million Public Offering (ACCESSWIRE)
Apr-10-24 09:00AM	Aptevo Therapeutics Provides Pipeline Update (ACCESSWIRE) -26.38%
Mar-18-24 06:00AM	Aptevo Participating in The Springtime Partnering Event, a Bio-Europe Conference (ACCESSWIRE) -8.12%
Mar-07-24 08:55AM	Alligator Bioscience and Aptevo Therapeutics Announce Positive Interim Data of Dose Escalation Phase of ALG.APV-527 Phase 1 Study in Solid Tumor Cancers Expressing Tumor Antigen 5T4 (ACCESSWIRE)
Mar-05-24 01:51PM	APVO Stock Earnings: Aptevo Therapeutics Beats EPS for Q4 2023 (InvestorPlace) -8.55%
08:05AM	Aptevo Therapeutics Reports 2023 Financial Results and Provides a Business Update (ACCESSWIRE)
Mar-04-24 09:00AM	Aptevo Therapeutics Announces 1-for 44 Reverse Stock Split As Part of Nasdaq Compliance Plan (ACCESSWIRE) -13.72%
Nov-14-23 08:05AM	Aptevo Therapeutics Reports 3Q23 Financial Results and Provides a Business Update (ACCESSWIRE) +6.82%
Nov-01-23 07:45AM	Aptevo to Present at Bio-Europe Conference (ACCESSWIRE)
Aug-10-23 08:05AM	Aptevo Therapeutics Reports 2Q23 Financial Results and Provides a Business Update (ACCESSWIRE) -9.68%
Aug-06-23 07:14AM	10 Oversold Value Stocks To Buy (Insider Monkey)
Aug-04-23 06:40PM	Aptevo Therapeutics Inc. Announces Closing of Previously Announced $5 Million Public Offering (ACCESSWIRE) -10.19%
Aug-01-23 10:15PM	Aptevo Therapeutics Inc. Announces Pricing of $5 Million Public Offering (ACCESSWIRE) -5.77% -38.30%
Jul-30-23 02:17PM	7 Millionaire-Maker Penny Stocks to Buy Before the Window Closes (InvestorPlace)
Jul-18-23 08:05AM	Aptevo Announces Positive Duration of Remission Data from Phase 1b Expansion Trial Evaluating the Bispecific APVO436 for AML (ACCESSWIRE) -23.24%
May-11-23 08:05AM	Aptevo Therapeutics Reports 1Q23 Financial Results and Provides Business Update (ACCESSWIRE)
Apr-01-23 08:51AM	Aptevo Therapeutics Full Year 2022 Earnings: EPS Beats Expectations (Simply Wall St.)
Mar-30-23 07:45AM	Aptevo Therapeutics Reports 2022 Financial Results and Provides Business Update (ACCESSWIRE)
07:30AM	Aptevo Therapeutics Raises $9.6 Million in Non-Dilutive Funding (ACCESSWIRE)
Mar-29-23 10:13AM	12 Cheap Healthcare Stocks to Buy in 2023 (Insider Monkey) +6.88%
Mar-03-23 06:57PM	The Top 7 Growth Stocks in Biotech (InvestorPlace)
Feb-13-23 08:05AM	Alligator Bioscience & Aptevo Therapeutics Announce Dosing of First Patient with ALG.APV-527 in Phase 1 Clinical Trial (ACCESSWIRE)
Jan-09-23 08:05AM	Aptevo Therapeutics Files Provisional Patent for Fifth Bispecific Antibody APVO711, Intended for the Treatment of Solid Tumors (ACCESSWIRE) +6.42%
Dec-12-22 09:54AM	Aptevo Stock Jumps As Acute Myeloid Leukemia Combo Therapy Achieves 100% Clinical Benefit Rate (Benzinga) +12.58%
07:35AM	100% Clinical Benefit Rate Achieved in Phase 1b Trial Evaluating APVO436 in Combination with Venetoclax and Azacitidine for Venetoclax Treatment Naïve Patients with Acute Myeloid Leukemia (AML) (ACCESSWIRE)
Nov-10-22 08:05AM	Aptevo Therapeutics Reports Third Quarter 2022 Financial Results and Business Highlights (ACCESSWIRE)
Nov-09-22 08:05AM	Alligator Bioscience & Aptevo Therapeutics Announce Publication Highlighting ALG.APV-527 Preclinical Data in Peer-Reviewed Journal Molecular Cancer Therapeutics (ACCESSWIRE)
Nov-03-22 09:06AM	Aptevo Therapeutics Announces Poster Presentation at the 64th American Society of Hematology Annual Meeting and Exposition (ACCESSWIRE)
Sep-19-22 08:45AM	Alligator Bioscience and Aptevo Therapeutics Announce that FDA has Issued a "May Proceed" Notification for the ALG.APV-527 IND (ACCESSWIRE)
Aug-11-22 08:05AM	Aptevo Therapeutics Reports Second Quarter 2022 Financial Results and Business Highlights (ACCESSWIRE)
Jun-09-22 08:05AM	Aptevo Therapeutics Announces New Preliminary Remission Data on Four Additional Patients Enrolled in On-going APVO436 Dose Expansion Phase 1b Trial for the Treatment of Acute Myeloid Leukemia (ACCESSWIRE) -14.44%
May-12-22 08:05AM	Aptevo Therapeutics Reports First Quarter 2022 Financial Results and Business Highlights (ACCESSWIRE) +11.26%
Apr-12-22 08:05AM	APVO442 Prostate Cancer Data Presented at the American Association for Cancer Research Annual Meeting (ACCESSWIRE)
Mar-29-22 08:05AM	Aptevo Therapeutics Announces Monotherapy Patient Received a Transplant in APVO436 Expansion Trial for the Treatment of Acute Myeloid Leukemia (ACCESSWIRE)
Mar-24-22 08:05AM	Aptevo Therapeutics Reports 2021 Financial Results and Provides Business Update (ACCESSWIRE) +32.82%
Feb-09-22 08:05AM	Aptevo Therapeutics Earns $10 Million Non-Dilutive Milestone Payment on Sales of RUXIENCE, Provides Company Update (ACCESSWIRE) +5.62%
Jan-21-22 08:05AM	Aptevo Therapeutics' Board Chairman, Fuad El-Hibri, Announces Retirement, Effective April 1, 2022 (ACCESSWIRE) -6.51%
Dec-15-21 08:05AM	Alligator Bioscience & Aptevo Therapeutics Announce Co-Publication in Peer-Reviewed Journal, "Nature Communication" (ACCESSWIRE)
Dec-10-21 05:38PM	Towercrest Capital Management Buys Aptevo Therapeutics Inc, PowerShares QQQ Trust Ser 1, ... (GuruFocus.com) -5.13%
Nov-23-21 08:05AM	Aptevo Therapeutics Reports First Complete Remission, Providing Clinical Update for Its Phase 1b Multi Center, Multi Cohort Expansion Trial in the Treatment of Acute Myeloid Leukemia (ACCESSWIRE) +162.81%
07:59AM	Aptevo Therapeutics Stock More Than Doubles After Leukemia Study News (Investing.com)
Nov-15-21 08:05AM	Aptevo Therapeutics Announces the Presentation of Two Abstracts at the Upcoming American Society of Hematology Annual Meeting (ACCESSWIRE) -16.49%
Nov-12-21 08:05AM	Aptevo Therapeutics Reports Third Quarter Financial Results With Business Highlights (ACCESSWIRE) -8.71%

Aptevo Therapeutics, Inc. is a clinical-stage biotechnology company, which engages on developing novel immunotherapies for the treatment of cancer. Its pipeline APVO436, ALG.APV-527, and APVO603 were developed based on the ADAPTIR modular protein platform technology and APVO442 was developed based on the new ADAPTIR-FLE platform technology. The ADAPTIR and ADAPTIR-FLEX are capable of generating differentiated bispecific and multi-specific antibodies with potentially unique mechanisms of action for the treatment of different types of cancer. The company was founded in February 2016 and is headquartered in Seattle, WA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Grant Grady III	Director	Nov 10 '25	Buy	1.49	13,513	20,134	13,514	Nov 12 04:33 PM

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APVO

Aptevo Therapeutics Inc

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