Septerna, Inc. is a clinical-stage biotechnology company, which engages in pioneering a new era of G protein-coupled receptor oral small molecule drug discovery powered by proprietary Native Complex PlatformTM. Its pipeline of product candidates focused initially on treating patients in three therapeutic areas: endocrinology, immunology and inflammation, and metabolic diseases. The company was founded by Robert Joseph Lefkowitz, Arthur Christopoulos, Patrick Sexton, and Jeffrey T. Finer in December 2019 and is headquartered in South San Francisco, CA. |  |
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| Insider Trading |
Relationship |
Date |
Transaction |
Cost |
#Shares |
Value ($) |
#Shares Total |
SEC Form 4 |
| Klein Uwe | SVP, Biological Sciences | Aug 18 '25 | Option Exercise | 4.10 | 23,008 | 94,367 | 23,008 | Aug 19 05:02 PM | | Finer Jeffrey | CEO and President | Apr 02 '25 | Option Exercise | 2.76 | 50,000 | 138,000 | 821,907 | Apr 04 04:13 PM | | Finer Jeffrey | CEO and President | Apr 03 '25 | Option Exercise | 2.76 | 5,000 | 13,800 | 826,907 | Apr 04 04:13 PM | | Ezekowitz Alan | Director | Mar 07 '25 | Buy | 6.93 | 13,319 | 92,270 | 117,420 | Mar 10 04:18 PM | | Ezekowitz Alan | Director | Mar 06 '25 | Buy | 6.00 | 41,355 | 248,130 | 104,101 | Mar 06 09:02 PM | | Ezekowitz Alan | Director | Mar 05 '25 | Buy | 5.82 | 37,835 | 220,260 | 62,746 | Mar 06 09:02 PM | | Ezekowitz Alan | Director | Mar 04 '25 | Buy | 6.35 | 7,491 | 47,544 | 24,911 | Mar 06 09:02 PM | | Finer Jeffrey | CEO and President | Feb 25 '25 | Buy | 5.68 | 10,000 | 56,765 | 764,907 | Feb 27 06:53 PM | | Finer Jeffrey | CEO and President | Feb 26 '25 | Buy | 5.70 | 4,000 | 22,796 | 768,907 | Feb 27 06:53 PM | | Finer Jeffrey | CEO and President | Feb 27 '25 | Buy | 5.80 | 3,000 | 17,400 | 771,907 | Feb 27 06:53 PM | | Labrucherie Gil M | Chief Financial Officer | Feb 25 '25 | Buy | 5.59 | 6,282 | 35,116 | 36,282 | Feb 27 06:51 PM | | Labrucherie Gil M | Chief Financial Officer | Feb 27 '25 | Buy | 5.85 | 3,718 | 21,750 | 40,000 | Feb 27 06:51 PM | | Third Rock Ventures VI, L.P. | 10% Owner | Feb 24 '25 | Buy | 6.00 | 18,861 | 113,147 | 4,211,659 | Feb 26 04:15 PM | | Third Rock Ventures VI, L.P. | 10% Owner | Feb 20 '25 | Buy | 5.92 | 612,674 | 3,627,030 | 3,765,130 | Feb 24 04:15 PM | | Third Rock Ventures VI, L.P. | 10% Owner | Feb 21 '25 | Buy | 5.94 | 427,668 | 2,540,348 | 4,192,798 | Feb 24 04:15 PM | | Labrucherie Gil M | Chief Financial Officer | Feb 20 '25 | Buy | 5.88 | 14,500 | 85,234 | 25,000 | Feb 21 06:06 PM | | Labrucherie Gil M | Chief Financial Officer | Feb 19 '25 | Buy | 5.51 | 10,500 | 57,813 | 10,500 | Feb 21 06:06 PM | | Labrucherie Gil M | Chief Financial Officer | Feb 21 '25 | Buy | 5.85 | 5,000 | 29,250 | 30,000 | Feb 21 06:06 PM | | RA CAPITAL MANAGEMENT, L.P. | Director | Oct 28 '24 | Buy | 18.00 | 4,170,000 | 75,060,000 | 5,523,915 | Oct 30 06:12 PM | | Third Rock Ventures V, L.P. | 10% Owner | Oct 28 '24 | Buy | 18.00 | 370,500 | 6,669,000 | 6,215,591 | Oct 28 04:53 PM | | Third Rock Ventures V, L.P. | 10% Owner | Oct 28 '24 | Buy | 18.00 | 279,500 | 5,031,000 | 3,152,456 | Oct 28 04:53 PM |
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