LYEL

Lyell Immunopharma Inc

Jun 04 • 04:00PM ET

13.05

+0.48 3.82 %

Healthcare • Biotechnology • USA • Small • NASD

Peers: EDIT BEAM NTLA BMRN CRSP INCY KRYS AXSM NBIX VSTM

| Held by: VTI VXF SCHA IBB VHT AVSC DFAS DFMC SCHB PRFZ

Index	-	P/E	-	EPS (ttm)	-12.74	Insider Own	66.70%	Shs Outstand	23.33M	Perf Week	-22.46%
Market Cap	304.51M	Forward P/E	-	EPS next Y	-7.99	Insider Trans	6.59%	Shs Float	7.77M	Perf Month	-36.71%
Enterprise Value	99.34M	PEG	-	EPS next Q	-2.03	Inst Own	18.96%	Short Float	17.25%	Perf Quarter	-40.82%
Income	-246.41M	P/S	10150.33	EPS this Y	52.16%	Inst Trans	0.57%	Short Ratio	14.53	Perf Half Y	-37.29%
Sales	0.03M	P/B	1.11	EPS next Y	-4.00%	ROA	-63.15%	Short Interest	1.34M	Perf YTD	-57.60%
Book/sh	11.73	P/C	1.20	EPS next 5Y	23.93%	ROE	-80.76%	52W High	45.00 -71.00%	Perf Year	-3.12%
Cash/sh	10.89	P/FCF	-	EPS past 3/5Y	-2.70% 0.99%	ROIC	-78.69%	52W Low	7.78 67.74%	Perf 3Y	-81.36%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	-92.48% -65.85%	Gross Margin	-33545.16%	Volatility	11.94% 8.26%	Perf 5Y	-
Dividend TTM	-	EV/Sales	3311.33	EPS Y/Y TTM	49.06%	Oper. Margin	-620790.32%	ATR (14)	1.45	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	7.23	Sales Y/Y TTM	-52.31%	Profit Margin	-794858.06%	RSI (14)	26.45	Recom	1.67
Dividend Gr. 3/5Y	- -	Current Ratio	7.23	EPS Q/Q	68.79%	SMA20	-24.03%	Beta	-0.06	Target Price	37.17
Payout	-	Debt/Eq	0.18	Sales Q/Q	-71.43%	SMA50	-35.03%	Rel Volume	1.38	Prev Close	12.57
Employees	161	LT Debt/Eq	0.14	Earnings	May 06 AMC	SMA200	-36.87%	Avg Volume	92.27K	Price	13.05
IPO	Jun 17, 2021	Option/Short	Yes / Yes	EPS/Sales Surpr.	16.14% -33.33%	Trades		Volume	127,300	Change	3.82%

Date	Action	Analyst	Rating Change	Price Target Change
May-01-26	Initiated	Robert W. Baird	Outperform	$49
Apr-10-26	Initiated	Needham	Buy	$44
Mar-09-26	Initiated	Citizens	Mkt Outperform	$34
Dec-09-25	Upgrade	H.C. Wainwright	Neutral → Buy	$45
Oct-30-24	Downgrade	BofA Securities	Buy → Underperform	$6 → $1
Jun-27-24	Downgrade	H.C. Wainwright	Buy → Neutral	$6 → $1
Aug-28-23	Downgrade	JP Morgan	Overweight → Neutral	$15 → $5
Nov-14-22	Downgrade	Morgan Stanley	Overweight → Equal-Weight	$15 → $7
Nov-11-22	Downgrade	Goldman	Buy → Neutral	$13 → $7
Oct-17-22	Initiated	H.C. Wainwright	Buy	$12
Jul-12-21	Initiated	Morgan Stanley	Overweight	$25
Jul-12-21	Initiated	JP Morgan	Overweight	$22
Jul-12-21	Initiated	Goldman	Buy	$30
Jul-12-21	Initiated	BofA Securities	Buy	$25

Show Previous Ratings

Jun-04-26 04:05PM	Lyell Immunopharma to Present Phase 1/2 Safety and Translational Data for Ronde-Cel in Large B-Cell Lymphoma at the European Hematology Association 2026 Congress (GlobeNewswire)
Jun-01-26 08:00AM	Lyell Immunopharma Announces Participation in Goldman Sachs 47th Annual Global Healthcare Conference 2026 (GlobeNewswire)
May-20-26 04:48PM	Down 33.7% in 4 Weeks, Here's Why You Should You Buy the Dip in Lyell Immunopharma (LYEL) (Quartz) +6.76%
May-12-26 08:00AM	Lyell Immunopharma Announces Participation in May Investor Conferences (GlobeNewswire)
May-06-26 05:17PM	Lyell Immunopharma: Q1 Earnings Snapshot (Associated Press)
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04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2026 (GlobeNewswire)
Apr-07-26 08:00AM	Lyell Immunopharma Announces Participation in 25th Annual Needham Virtual Healthcare Conference (GlobeNewswire)
Mar-12-26 06:10PM	Lyell Immunopharma: Q4 Earnings Snapshot (Associated Press Finance) -14.23%
04:05PM	Lyell Immunopharma Reports Q4 and Full Year 2025 Business and Financial Results (GlobeNewswire)
Mar-09-26 08:00AM	Lyell Immunopharma Announces Closing of Additional $50 Million Tranche of Equity Private Placement and Appointment of Smital Shah as Chief Financial and Business Officer (GlobeNewswire) +13.54%
Feb-23-26 08:00AM	Lyell Immunopharma Announces Participation in March Investor Conferences (GlobeNewswire) +6.12%
Feb-13-26 06:00AM	Lyell starts first-of-its-kind CAR-T trial; New coalition aims to boost European biotechs (BioPharma Dive)
Feb-12-26 07:30AM	Lyell Immunopharma Announces Initiation of Patient Dosing in First-of-Its-Kind Phase 3 Head-To-Head CAR T-Cell Clinical Trial in Aggressive Large B-Cell Lymphoma (GlobeNewswire)
Dec-26-25 02:33AM	The Zacks Analyst Blog Mineralys, Lyell, Insmed and Nektar (Zacks) -9.09%
Dec-24-25 10:51AM	4 Drug, Biotech Stocks Rising More Than 50% in 2025 With Room to Grow (Zacks)
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Dec-19-25 07:44AM	Immunotherapies Replacing Chemotherapy as Blood Cancer Market to Hit $13B by 2030 (PR Newswire)
Dec-07-25 04:30PM	Lyell Immunopharma Presents New Clinical Data from Ongoing Trial of Ronde-Cel Showing High Rates of Durable Complete Responses in Patients with Large B-cell Lymphoma at the 67th ASH Annual Meeting and Exposition (GlobeNewswire)
Nov-12-25 05:40PM	Lyell Immunopharma: Q3 Earnings Snapshot (Associated Press Finance)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Third Quarter 2025 (GlobeNewswire)
05:20AM	Metagenomi, Ovid CEOs step aside; Cogent soars on unprecedented stomach cancer data (BioPharma Dive)
Nov-11-25 08:44AM	Lyell acquires worldwide rights from ICT to CAR T-cell therapy (Pharmaceutical Technology)
Nov-10-25 07:30AM	Lyell Immunopharma Acquires Exclusive Global Rights to a Next-Generation CAR T-Cell Product Candidate in Clinical Development for Metastatic Colorectal Cancer (GlobeNewswire)
Nov-03-25 09:00AM	Lyell Announces Two Oral Presentations from the Phase 1/2 Clinical Trial of Ronde-Cel for the Treatment of Aggressive Large B-Cell Lymphoma at the 67th ASH Annual Meeting and Exposition (GlobeNewswire)
Sep-03-25 08:00AM	Lyell Immunopharma Announces the Initiation of a Phase 3 Head-to-Head CAR T-Cell Therapy Clinical Trial in Aggressive Large B-Cell Lymphoma and Formation of Expert Steering Committee (GlobeNewswire)
Sep-02-25 04:05PM	Lyell Immunopharma Announces Participation in September Investor Conferences (GlobeNewswire)
Aug-12-25 06:17PM	Lyell Immunopharma: Q2 Earnings Snapshot (Associated Press Finance)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Second Quarter 2025 (GlobeNewswire)
Jul-29-25 03:46PM	Biotech Underdogs Line Up for Pivotal Shots at Game-Changing Cancer Treatments (PR Newswire) -6.26%
Jul-25-25 08:00AM	Lyell Immunopharma Announces up to $100 Million Equity Private Placement (GlobeNewswire) +19.31%
Jun-23-25 05:00PM	Lyell Immunopharma to Participate in the H.C. Wainwright "HCW@Home" Series (GlobeNewswire) +6.62%
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Jun-18-25 07:12AM	Lyell reports new clinical data from trial of large B-cell lymphoma therapy (Clinical Trials Arena)
Jun-17-25 06:30AM	Lyell Immunopharma Announces Positive New Clinical Data Demonstrating High Rates of Durable Complete Responses from the Phase 1/2 Trial of LYL314 for the Treatment of Aggressive Large B-cell Lymphoma (GlobeNewswire)
Jun-09-25 04:05PM	Lyell Immunopharma Strengthens Clinical and Commercial Capabilities with Key Board and Executive Appointments (GlobeNewswire) -13.39%
Jun-04-25 04:05PM	Lyell Immunopharma to Participate in the Goldman Sachs Global Healthcare Conference (GlobeNewswire) +68.59% -14.92%
May-13-25 05:49PM	Lyell Immunopharma: Q1 Earnings Snapshot (Associated Press Finance)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2025 (GlobeNewswire)
May-01-25 09:00AM	Lyell Immunopharma Announces Oral Presentation of New Clinical Data from the Phase 1/2 Trial of LYL314 for the Treatment of Large B-cell Lymphoma at the International Conference on Malignant Lymphoma (ICML) 2025 (GlobeNewswire)
Apr-15-25 09:00AM	Lyell Immunopharma Receives Regenerative Medicine Advanced Therapy (RMAT) Designation for LYL314 for the Treatment of Relapsed and/or Refractory Large B-Cell Lymphoma (GlobeNewswire)
Mar-28-25 10:54AM	Is Lyell Immunopharma, Inc. (LYEL) the Cheapest Stock Insiders Are Buying In March? (Insider Monkey) -8.83%
Mar-11-25 04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Fourth Quarter and Full Year 2024 (GlobeNewswire)
Feb-18-25 04:05PM	Lyell Immunopharma Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Jan-22-25 12:00PM	Lyell Immunopharma (LYEL) Upgraded to Strong Buy: Here's Why (Zacks)
Jan-09-25 09:00AM	Lyell to Highlight Vision for its Next-Generation CAR T-Cell Therapy Pipeline at 43rd Annual JP Morgan Healthcare Conference (GlobeNewswire)
Dec-31-24 09:35AM	After Plunging -37.9% in 4 Weeks, Here's Why the Trend Might Reverse for Lyell Immunopharma (LYEL) (Zacks)
Dec-30-24 09:35AM	After Plunging -31.22% in 4 Weeks, Here's Why the Trend Might Reverse for Lyell Immunopharma (LYEL) (Zacks)
Dec-13-24 09:35AM	Down -30.89% in 4 Weeks, Here's Why Lyell Immunopharma (LYEL) Looks Ripe for a Turnaround (Zacks) -11.37%
Dec-09-24 09:00PM	Lyell Presents Positive Initial Clinical Data from the Phase 1-2 Clinical Trial of IMPT-314 for the Treatment of B-cell Lymphoma at the 2024 ASH Annual Meeting (GlobeNewswire)
Nov-14-24 12:00PM	Lyell Immunopharma (LYEL) Upgraded to Buy: Here's What You Should Know (Zacks)
Nov-07-24 05:22PM	Lyell Immunopharma: Q3 Earnings Snapshot (Associated Press Finance) -17.57%
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Third Quarter 2024 (GlobeNewswire)
Nov-05-24 09:30AM	Lyell Announces Presentation of Initial Clinical Data from the Phase 1-2 Clinical Trial of IMPT-314 for the treatment of B-cell Lymphoma at the 2024 American Society of Hematology (ASH) Annual Meeting (GlobeNewswire)
Oct-31-24 04:00PM	Lyell Immunopharma Completes Acquisition of ImmPACT Bio (GlobeNewswire) +11.88% +16.63%
Oct-30-24 11:16AM	Lyell shares down as BofA double downgrades to Sell (Investing.com) -9.47%
Oct-25-24 11:56AM	Lyell goes all in on CAR-T therapies, buys ImmPACT Bio and trims pipeline (Pharmaceutical Technology) -14.95%
Oct-24-24 04:00PM	Lyell Immunopharma to Acquire ImmPACT Bio and Prioritizes its Pipeline to Focus on Next-Generation CAR T-cell Therapies (GlobeNewswire) -5.22%
01:54PM	Lyell, in search of a turnaround, to buy cell therapy startup ImmPact (BioPharma Dive)
Oct-04-24 09:00AM	Lyell Immunopharma Announces the Acceptance Abstracts for Presentation at 2024 Society for Immunotherapy of Cancer (SITC) Annual Meeting (GlobeNewswire)
Sep-24-24 04:05PM	Lyell Immunopharma Announces Participation in Goldman Sachs Cell Therapy Day (GlobeNewswire) -7.53%
Aug-28-24 04:05PM	Lyell Immunopharma Announces Participation in September Investor Conferences (GlobeNewswire)
Aug-07-24 05:41PM	Lyell Immunopharma: Q2 Earnings Snapshot (Associated Press Finance) +6.38%
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Second Quarter 2024 (GlobeNewswire)
Aug-06-24 08:00AM	3 Biotech Stocks to Sell in August Before They Crash & Burn (InvestorPlace)
Jun-26-24 02:44PM	Lyell Immunopharma Shares Plunge On One Patient Death In CAR-T Cell Therapy Cancer Trial (Benzinga) -36.03%
07:00AM	Lyell Immunopharma Reports Dose-dependent Clinical Activity from Phase 1 Trial of LYL797, a ROR1-targeted CAR-T Cell Product Candidate Enhanced with its Proprietary Anti-exhaustion Technology (GlobeNewswire)
Jun-03-24 04:05PM	Lyell Immunopharma to Participate in the Goldman Sachs Global Healthcare Conference (GlobeNewswire) -5.68%
May-07-24 04:05PM	Lyell Immunopharma to Participate in BofA Securities Health Care Conference (GlobeNewswire)
May-06-24 10:53PM	LYEL Stock Earnings: Lyell Immunopharma Beats EPS for Q1 2024 (InvestorPlace) +7.63%
01:34PM	Lyell Immunopharma Shares Rise After Q1 Net Loss Narrows (MT Newswires)
08:23AM	Lyell Immunopharma: Q1 Earnings Snapshot (Associated Press Finance)
08:00AM	Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2024 (GlobeNewswire)
Mar-19-24 10:00AM	CHARM Therapeutics Announces Foundation of Scientific Advisory Board (SAB) (GlobeNewswire)
Mar-07-24 12:00PM	Lyell Immunopharma (LYEL) Is Up 28.45% in One Week: What You Should Know (Zacks)
Mar-05-24 04:30PM	Lyell Immunopharma Announces the Acceptance of Three Abstracts for Presentation at 2024 AACR Annual Meeting (GlobeNewswire) +5.18%
Feb-28-24 04:44PM	Lyell Immunopharma Inc (LYEL) Reports 2023 Financial Results and Business Highlights (GuruFocus.com)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Fourth Quarter and Full Year 2023 (GlobeNewswire)
Feb-26-24 04:05PM	Lyell Immunopharma Announces Participation in March Investor Conferences (GlobeNewswire) +9.62% +8.78%
Jan-03-24 04:05PM	Lyell Immunopharma to Participate in 42nd Annual J.P. Morgan Healthcare Conference (GlobeNewswire) -5.69%
Nov-09-23 04:05PM	Lyell Immunopharma Receives FDA Orphan Drug Designation for LYL845 for the Treatment of Melanoma (GlobeNewswire) -6.81% -24.43%
Nov-07-23 04:33PM	Lyell Immunopharma: Q3 Earnings Snapshot (Associated Press Finance)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Third Quarter 2023 (GlobeNewswire)
Oct-31-23 09:00AM	Lyell Immunopharma Presentations at SITC Highlight New Nonclinical Data on Product Candidates and Innovative Technology to Shorten TIL Manufacturing (GlobeNewswire) -7.54%
Sep-27-23 09:00AM	Lyell Immunopharma Announces the Acceptance of Six Abstracts for Presentation at 2023 Society for Immunotherapy of Cancer (SITC) Annual Meeting (GlobeNewswire)
Sep-11-23 08:00AM	Cellares and Lyell to Evaluate Automated Manufacturing of Lyells CAR T-Cell Therapy on Cellares Cell Shuttle Platform (GlobeNewswire) +9.89%
Aug-31-23 04:05PM	Lyell Immunopharma to Participate in Upcoming Investor Conferences (GlobeNewswire)
Aug-08-23 07:10PM	Lyell Immunopharma: Q2 Earnings Snapshot (Associated Press Finance)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Second Quarter 2023 (GlobeNewswire)
Jul-12-23 08:47AM	Lyell Immunopharma (NASDAQ:LYEL) Is In A Good Position To Deliver On Growth Plans (Simply Wall St.)
Jul-05-23 04:05PM	Lyell Immunopharma Appoints Matthew Lang as Chief Business Officer (GlobeNewswire) -6.98%
Jun-16-23 10:47AM	Why Shares of Lyell Immunopharma Jumped This Week (Motley Fool) -17.36%
Jun-07-23 04:05PM	Lyell Immunopharma to Participate in the Goldman Sachs Global Healthcare Conference (GlobeNewswire) -5.52%
Jun-01-23 07:55AM	Even after rising 12% this past week, Lyell Immunopharma (NASDAQ:LYEL) shareholders are still down 31% over the past year (Simply Wall St.)
May-04-23 07:25PM	Lyell Immunopharma (LYEL) Reports Q1 Loss, Lags Revenue Estimates (Zacks)
06:25PM	Lyell Immunopharma: Q1 Earnings Snapshot (AP Finance)
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the First Quarter 2023 (GlobeNewswire)
May-02-23 04:05PM	Lyell Immunopharma to Participate in BofA Securities Healthcare Conference (GlobeNewswire) +12.08%
Apr-17-23 07:11AM	There's No Escaping Lyell Immunopharma, Inc.'s (NASDAQ:LYEL) Muted Revenues (Simply Wall St.) +7.63%
Mar-27-23 04:52AM	Aurinia (AUPH) Surges 11.0%: Is This an Indication of Further Gains? (Zacks) +8.96%
Mar-26-23 10:14AM	Lyell Immunopharma, Inc. (NASDAQ:LYEL) has caught the attention of institutional investors who hold a sizeable 47% stake (Simply Wall St.)
Feb-28-23 08:15PM	Lyell Immunopharma (LYEL) Reports Q4 Loss, Tops Revenue Estimates (Zacks) +11.63%
04:05PM	Lyell Immunopharma Reports Business Highlights and Financial Results for the Fourth Quarter and Full Year 2022 (GlobeNewswire)

Lyell Immunopharma, Inc. operates as a holding company, which engages in the development of cell-based immunotherapies for human diseases. The company was founded by Richard D. Klausner, Stan Riddell, and Crystal Mackall in June 2018 and is headquartered in South San Francisco, CA.

Founder & Executive ChairmanDr. Richard D. Klausner M.D.

Ph.D.Dr. Lynn Seely M.D.

Chief Operating OfficerMr. Stephen J. Hill

Chief Scientific OfficerDr. Gary K. Lee Ph.D.

Founder & Scientific AdvisorProf. Stanley R. Riddell M.D.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
ARCH Venture Partners IX, LLC	10% Owner	Mar 06 '26	Buy	25.61	488,090	12,499,985	1,426,528	Mar 09 04:36 PM
ARCH Venture Fund XIII, L.P.	10% Owner	Mar 06 '26	Buy	25.61	488,090	12,499,985	1,426,528	Mar 09 04:34 PM
Seely Lynn	President and CEO	Feb 11 '26	Sale	23.39	7,455	174,372	74,266	Feb 12 08:47 PM
Hill Stephen J.	Chief Operating Officer	Feb 11 '26	Sale	23.39	1,236	28,910	17,795	Feb 12 08:46 PM
Lee Gary K.	Chief Scientific Officer	Feb 11 '26	Sale	23.39	1,671	39,085	16,938	Feb 12 08:44 PM
Hill Stephen J.	Chief Operating Officer	Feb 10 '26	Sale	23.12	109	2,520	19,031	Feb 11 09:05 PM
Lee Gary K.	Chief Scientific Officer	Feb 10 '26	Sale	23.12	147	3,399	18,609	Feb 11 09:04 PM
Seely Lynn	President and CEO	Feb 10 '26	Sale	23.12	438	10,127	81,721	Feb 11 09:03 PM
Bulis Veronica Sanchez	VP, Corporate Controller	Feb 10 '26	Sale	23.12	254	5,872	15,637	Feb 11 09:00 PM
Bulis Veronica Sanchez	VP, Corporate Controller	Dec 24 '25	Sale	38.67	1,136	43,929	8,077	Jan 06 04:02 PM
Bulis Veronica Sanchez	VP, Corporate Controller	Dec 30 '25	Sale	32.32	936	30,252	7,141	Jan 06 04:02 PM
Seely Lynn	President and CEO	Nov 10 '25	Sale	16.11	412	6,637	67,159	Nov 12 08:36 PM
Bulis Veronica Sanchez	VP, Corporate Controller	Nov 10 '25	Sale	16.10	239	3,848	9,213	Nov 12 08:34 PM
Lee Gary K.	Chief Scientific Officer	Nov 10 '25	Sale	16.16	138	2,230	15,366	Nov 12 08:33 PM
Hill Stephen J.	Chief Operating Officer	Nov 10 '25	Sale	16.12	95	1,531	15,750	Nov 12 08:31 PM
Seely Lynn	President and CEO	Aug 21 '25	Sale	10.54	7,257	76,518	67,571	Aug 22 04:07 PM
Hill Stephen J.	Chief Operating Officer	Aug 21 '25	Sale	10.54	1,004	10,586	15,845	Aug 22 04:06 PM
Newton Charles W.	Chief Financial Officer	Aug 21 '25	Sale	10.54	1,453	15,320	15,306	Aug 22 04:03 PM
Lee Gary K.	Chief Scientific Officer	Aug 21 '25	Sale	10.54	1,453	15,320	15,504	Aug 22 04:02 PM
Seely Lynn	President and CEO	Aug 12 '25	Sale	10.34	406	4,197	34,828	Aug 13 09:10 PM
Seely Lynn	President and CEO	Aug 11 '25	Sale	10.53	391	4,116	35,234	Aug 13 09:10 PM
Hill Stephen J.	Chief Operating Officer	Aug 12 '25	Sale	10.34	94	972	8,849	Aug 13 09:09 PM
Hill Stephen J.	Chief Operating Officer	Aug 11 '25	Sale	10.53	91	958	8,943	Aug 13 09:09 PM
Lee Gary K.	Chief Scientific Officer	Aug 12 '25	Sale	10.34	136	1,406	8,957	Aug 13 09:08 PM
Lee Gary K.	Chief Scientific Officer	Aug 11 '25	Sale	10.53	131	1,379	9,093	Aug 13 09:08 PM
Newton Charles W.	Chief Financial Officer	Aug 12 '25	Sale	10.34	136	1,406	8,759	Aug 13 09:06 PM
Newton Charles W.	Chief Financial Officer	Aug 11 '25	Sale	10.53	131	1,379	8,895	Aug 13 09:06 PM

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LYEL

Lyell Immunopharma Inc

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