Upgrade to Finviz Elite: Get our fastest platform speed, real-time data, and unlimited screening & charting. Start Free Trial

SPRB

Spruce Biosciences Inc

Jun 08 • 04:00PM ET

49.32

-1.11 -2.20 %

Healthcare • Biotechnology • USA • Micro • NASD

Today, 4:45 PMSpruce Biosciences reports six-year tralesinidase alfa data in Sanfilippo B showing durable heparan sulfate reduction and stabilized cognitive and motor function

Peers: ANTX BDTX TNYA MOLN HURA MENS MSLE OKUR ORMP PLX

| Held by: VTI VXF DFAS DFMC DFAC DCOR

Scroll to Statements

Index	-	P/E	-	EPS (ttm)	-37.70	Insider Own	16.68%	Shs Outstand	2.75M	Perf Week	-2.72%
Market Cap	135.74M	Forward P/E	-	EPS next Y	-3.87	Insider Trans	0.00%	Shs Float	2.29M	Perf Month	-12.82%
Enterprise Value	88.78M	PEG	-	EPS next Q	-5.15	Inst Own	25.60%	Short Float	9.39%	Perf Quarter	-20.59%
Income	-37.19M	P/S	-	EPS this Y	55.05%	Inst Trans	-0.68%	Short Ratio	3.45	Perf Half Y	-45.47%
Sales	0.00M	P/B	1.95	EPS next Y	83.05%	ROA	-84.70%	Short Interest	0.22M	Perf YTD	-43.38%
Book/sh	25.25	P/C	2.51	EPS next 5Y	34.33%	ROE	-148.85%	52W High	240.00 -79.45%	Perf Year	929.11%
Cash/sh	19.65	P/FCF	-	EPS past 3/5Y	29.85% 11.80%	ROIC	-91.96%	52W Low	4.35 1033.79%	Perf 3Y	-71.78%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	- -	Gross Margin	-	Volatility	6.62% 6.68%	Perf 5Y	-94.87%
Dividend TTM	-	EV/Sales	-	EPS Y/Y TTM	61.98%	Oper. Margin	-	ATR (14)	3.78	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	4.67	Sales Y/Y TTM	-100.00%	Profit Margin	-	RSI (14)	41.88	Recom	1.00
Dividend Gr. 3/5Y	- -	Current Ratio	4.67	EPS Q/Q	62.69%	SMA20	-5.35%	Beta	3.22	Target Price	158.00
Payout	-	Debt/Eq	0.21	Sales Q/Q	-	SMA50	-14.42%	Rel Volume	0.50	Prev Close	50.43
Employees	8	LT Debt/Eq	0.17	Earnings	May 13 BMO	SMA200	-29.56%	Avg Volume	62.33K	Price	49.32
IPO	Oct 09, 2020	Option/Short	No / Yes	EPS/Sales Surpr.	-12.68% -	Trades		Volume	31,018	Change	-2.20%

Date	Action	Analyst	Rating Change	Price Target Change
Apr-27-26	Initiated	Craig Hallum	Buy	$140
Dec-23-25	Initiated	Oppenheimer	Outperform	$283
Dec-03-25	Upgrade	Leerink Partners	Market Perform → Outperform	$160
Oct-28-25	Upgrade	Citizens JMP	Mkt Perform → Mkt Outperform	$254

Today 04:05PM	Spruce Biosciences Announces Long-Term Tralesinidase Alfa Enzyme Replacement Therapy Data in Sanfilippo Syndrome Type B (MPS IIIB) Presented at the 18th International MPS Symposium (Business Wire)
May-28-26 04:05PM	Spruce Biosciences Announces Data Presentation at the 18th International MPS Symposium (Business Wire)
May-27-26 04:05PM	Spruce Biosciences to Participate in Upcoming Conferences in June (Business Wire)
May-13-26 08:00AM	Spruce Biosciences Reports First Quarter 2026 Financial Results and Provides Corporate Updates (Business Wire)
May-04-26 08:00AM	Spruce Biosciences Further Strengthens its Commercial Leadership Team with the Appointments of Brian Walls as Vice President, Market Access and Darren Johnson as Vice President, Commercial Operations (Business Wire)
11:45PM	Loading…
Apr-20-26 11:45PM	Spruce Biosciences Announces Pricing of Public Offering of Common Stock and Pre-Funded Warrants (Business Wire) -26.05%
04:01PM	Spruce Biosciences Announces Proposed Public Offering of Common Stock and Pre-Funded Warrants (Business Wire)
Apr-03-26 08:00PM	Wall Street Analysts Believe Spruce Biosciences (SPRB) Could Rally 181.21%: Here's is How to Trade (Quartz)
Mar-09-26 07:05AM	Spruce Biosciences Reports Full Year 2025 Financial Results and Provides Corporate Updates (Business Wire) +11.17%
07:00AM	Spruce Biosciences Appoints Dale Hooks, an Accomplished Rare Disease Commercial Leader, as Chief Commercial Officer (Business Wire)
Mar-03-26 10:20AM	Spruce Biosciences (SPRB) Gains FDA Support for Accelerated Approval Pathway (Insider Monkey)
Mar-02-26 04:05PM	Spruce Biosciences to Present at Upcoming Investor Conferences in March (Business Wire)
Mar-01-26 05:37PM	Spruce Biosciences Touts MPS IIIB Data, Targets Q4 BLA Submission at Oppenheimer Conference (MarketBeat)
Feb-18-26 07:00AM	Spruce Biosciences Announces Positive Type B Meetings with U.S. FDA for TA-ERT for the Treatment of Sanfilippo Syndrome Type B (MPS IIIB) (Business Wire) -8.18%
Feb-17-26 04:05PM	Spruce Biosciences to Participate in the Oppenheimer 36th Annual Healthcare Life Sciences Conference (Business Wire) -12.14%
04:05PM	Loading…
Feb-05-26 04:05PM	Long-Term Data Presented at the 22nd Annual WORLDSymposium Highlights Tralesinidase Alfa Enzyme Replacement Therapys Potential as the First Disease-Modifying Treatment Option for Sanfilippo Syndrome Type B (MPS IIIB) (Business Wire) -10.58%
Feb-03-26 08:00AM	Spruce Biosciences Adds Regulatory and Clinical Development Expertise to Leadership Team (Business Wire) +7.05%
Jan-28-26 08:00AM	Spruce Biosciences Announces Data Presentations at the 22nd Annual WORLDSymposium (Business Wire)
Jan-21-26 07:24AM	Big-Pharma Partner Harbour BioMed Boosts Stake In Spruce Biosciences (Benzinga) +10.44%
Jan-18-26 07:02PM	Harbour BioMed Acquires Common Stock in Spruce Biosciences, Deepening Strategic Collaboration (PR Newswire)
Jan-08-26 08:00AM	Spruce Biosciences Secures Up to $50 Million in Growth Capital from Avenue Capital (Business Wire) -5.62%
Dec-24-25 06:30AM	Spruce Biosciences initiated with an Outperform at Oppenheimer (TipRanks)
Dec-23-25 09:33AM	Coty downgraded, Spruce Biosciences initiated: Wall Street's top analyst calls (The Fly)
08:13AM	Here Are Tuesdays Top Wall Street Analyst Research Calls: AMETEK, Coty, Janus Henderson, Levi Strauss, Pool Corporation, Southern Copper, and More (24/7 Wall St.)
Dec-15-25 08:00AM	Spruce Biosciences Appoints Proven Pharmaceutical Commercial Leader Keli Walbert to Board of Directors (Business Wire)
Nov-10-25 04:05PM	Spruce Biosciences Reports Third Quarter 2025 Financial Results and Provides Corporate Updates (Business Wire) -8.97%
Oct-15-25 12:00PM	What Makes Spruce Biosciences, Inc. (SPRB) a Strong Momentum Stock: Buy Now? (Zacks) -10.09%
Oct-08-25 08:00AM	Spruce Biosciences Announces $50.0 Million Private Placement Financing (Business Wire) -12.34%
Oct-07-25 09:44AM	This Biotech Stock Soared 1,400%. Investors Are Optimistic About Its Rare-Disease Drug. (Barrons.com) +40.03%
Oct-06-25 05:04PM	Why Spruce Biosciences Just Skyrocketed Almost 1,400% (Investor's Business Daily) +1,378.46%
08:00AM	Loading…
08:00AM	Spruce Biosciences Receives U.S. FDA Breakthrough Therapy Designation for Tralesinidase Alfa Enzyme Replacement Therapy (TA-ERT) in Sanfilippo Syndrome Type B (MPS IIIB) (Business Wire)
Sep-15-25 07:00AM	Spruce Biosciences Resumes Trading on the Nasdaq Capital Market (Business Wire) -20.97%

Spruce Biosciences, Inc. is a biopharmaceutical company, which engages in developing and commercializing novel therapies for rare endocrine disorders with significant unmet medical need. The company was founded on November 13, 2014 and is headquartered in South San Francisco, CA.

Executive ChairmanMr. Michael G. Grey

M.P.H.Dr. Javier Szwarcberg M.D.

M.B.A.Mr. Samir M. Gharib CPA

Ph.D.Dr. Kirk Ways M.D.

M.Sc.Mr. Bruno Gagnon BPHARM

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Ways Douglas Kirk	Interim Chief Medical Officer	Dec 11 '25	Option Exercise	0.00	1,250	0	1,250	Jan 21 04:04 PM
Gharib Samir M.	PRESIDENT AND CFO	Dec 15 '25	Option Exercise	0.00	1,009	0	8,447	Dec 17 04:58 PM
Szwarcberg Javier B.	CHIEF EXECUTIVE OFFICER	Dec 15 '25	Option Exercise	0.00	2,676	0	14,922	Dec 17 04:56 PM
Gharib Samir M.	PRESIDENT AND CFO	Dec 11 '25	Option Exercise	0.00	1,900	0	8,296	Dec 12 07:05 PM
Gharib Samir M.	PRESIDENT AND CFO	Dec 10 '25	Option Exercise	0.00	514	0	6,580	Dec 12 07:05 PM
Szwarcberg Javier B.	CHIEF EXECUTIVE OFFICER	Dec 11 '25	Option Exercise	0.00	4,950	0	15,192	Dec 12 07:03 PM
Szwarcberg Javier B.	CHIEF EXECUTIVE OFFICER	Dec 10 '25	Option Exercise	0.00	1,196	0	10,670	Dec 12 07:03 PM
Gharib Samir M.	PRESIDENT AND CFO	Oct 20 '25	Option Exercise	0.00	2,053	0	6,727	Oct 22 04:15 PM
Szwarcberg Javier B.	CHIEF EXECUTIVE OFFICER	Oct 20 '25	Option Exercise	0.00	4,784	0	11,013	Oct 22 04:15 PM
Parkman Healthcare Partners LL	10% Owner	Oct 06 '25	Buy	17.91	256	4,585	1,307	Oct 15 04:32 PM
Parkman Healthcare Partners LL	10% Owner	Oct 06 '25	Sale	19.14	257	4,920	1,050	Oct 15 04:32 PM
Parkman Healthcare Partners LL	10% Owner	Oct 06 '25	Buy	17.91	256	4,585	1,307	Oct 08 08:55 PM
Parkman Healthcare Partners LL	10% Owner	Oct 06 '25	Sale	19.14	257	4,920	1,050	Oct 08 08:55 PM

open in yahoo | open in reuters | open in marketwatch | open in google | open in EDGAR

SPRB

Spruce Biosciences Inc

Upgrade your Finviz experience