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GYRE

Gyre Therapeutics Inc

May 29 • 04:00PM ET

5.91

+0.17 2.96 %

Healthcare • Biotechnology • USA • Small • NASD

Peers: INCY KYMR NUVL BMRN RYTM VKTX KRYS AXSM MDGL NBIX

| Held by: VTI VXF IWM SCHA IWO VTWO EES SCHB VTWG DFMC

Scroll to Statements

Index	RUT	P/E	-	EPS (ttm)	-0.08	Insider Own	81.07%	Shs Outstand	91.34M	Perf Week	-4.37%
Market Cap	573.23M	Forward P/E	-	EPS next Y	-0.10	Insider Trans	-0.10%	Shs Float	18.36M	Perf Month	-19.59%
Enterprise Value	559.92M	PEG	-	EPS next Q	-0.06	Inst Own	3.53%	Short Float	9.13%	Perf Quarter	-28.28%
Income	-6.36M	P/S	4.90	EPS this Y	-1550.00%	Inst Trans	0.18%	Short Ratio	16.55	Perf Half Y	-23.45%
Sales	117.05M	P/B	5.33	EPS next Y	65.52%	ROA	-4.36%	Short Interest	1.68M	Perf YTD	-16.29%
Book/sh	1.11	P/C	11.51	EPS next 5Y	-	ROE	-7.51%	52W High	9.93 -40.45%	Perf Year	-37.53%
Cash/sh	0.51	P/FCF	335.22	EPS past 3/5Y	-63.33% -	ROIC	-6.28%	52W Low	5.67 4.23%	Perf 3Y	74.72%
Dividend Est.	-	EV/EBITDA	110.44	Sales past 3/5Y	4.46% 40.96%	Gross Margin	95.09%	Volatility	4.10% 5.16%	Perf 5Y	-43.30%
Dividend TTM	-	EV/Sales	4.78	EPS Y/Y TTM	-182.23%	Oper. Margin	2.06%	ATR (14)	0.33	Perf 10Y	-90.10%
Dividend Ex-Date	Jan 13, 2023	Quick Ratio	4.06	Sales Y/Y TTM	16.30%	Profit Margin	-5.44%	RSI (14)	33.82	Recom	1.00
Dividend Gr. 3/5Y	- -	Current Ratio	4.64	EPS Q/Q	-2334.88%	SMA20	-12.95%	Beta	1.83	Target Price	18.67
Payout	0.00%	Debt/Eq	0.01	Sales Q/Q	2.09%	SMA50	-17.16%	Rel Volume	1.06	Prev Close	5.74
Employees	625	LT Debt/Eq	0.00	Earnings	May 07 BMO	SMA200	-22.53%	Avg Volume	101.26K	Price	5.91
IPO	Apr 12, 2006	Option/Short	Yes / Yes	EPS/Sales Surpr.	-36.43% -28.75%	Trades		Volume	107,665	Change	2.96%

Date	Action	Analyst	Rating Change	Price Target Change
Oct-10-25	Initiated	Jefferies	Buy	$16
Aug-26-25	Initiated	H.C. Wainwright	Buy	$18
Mar-11-25	Initiated	Noble Capital Markets	Outperform
Apr-29-21	Resumed	Stephens	Overweight	$18 → $19
Feb-10-21	Initiated	Piper Sandler	Overweight	$15
May-21-20	Initiated	Raymond James	Outperform	$20
Jan-04-19	Initiated	Oppenheimer	Outperform	$24
Feb-12-18	Reiterated	B. Riley FBR, Inc.	Buy	$19 → $49
Feb-09-18	Reiterated	Chardan Capital Markets	Buy	$37.50 → $75
Feb-09-18	Reiterated	Chardan Capital Markets	Buy	$10 → $75
Dec-08-17	Initiated	B. Riley FBR, Inc.	Buy	$19
Jun-12-17	Initiated	Chardan Capital Markets	Buy	$10
Jun-06-17	Initiated	Ladenburg Thalmann	Buy	$11
Jun-30-16	Initiated	Rodman & Renshaw	Buy	$3.50

Show Previous Ratings

May-12-26 04:05PM	Gyre Therapeutics Announces NMPA Acceptance of New Drug Application for F351 (hydronidone) for CHB-Induced Liver Fibrosis Treatment (GlobeNewswire)
May-07-26 06:00AM	Gyre Therapeutics Reports First Quarter 2026 Results and Provides Business Update (GlobeNewswire) -12.06%
May-04-26 08:47AM	Gyre Therapeutics Completes Acquisition of Cullgen to Create U.S.- and China-based Fully Integrated Biopharmaceutical Company (GlobeNewswire)
Mar-17-26 07:00AM	Gyre Therapeutics Announces China's NMPA Grants Priority Review to the NDA for Hydronidone (F351) for CHB-Induced Liver Fibrosis Treatment (GlobeNewswire)
Mar-12-26 06:00AM	Gyre Therapeutics Reports Fourth Quarter and Full Year 2025 Financial Results and Provides Business Update (GlobeNewswire) -6.30%
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Mar-10-26 08:35AM	ADC Therapeutics SA (ADCT) Reports Q4 Loss, Tops Revenue Estimates (Zacks)
Mar-09-26 05:15PM	Voyager Therapeutics (VYGR) Reports Q4 Loss, Beats Revenue Estimates (Zacks) +5.84%
Mar-03-26 08:23AM	Gyre Therapeutics to acquire Cullgen in $300M all-stock transaction (TipRanks) -9.82%
Feb-24-26 07:30PM	Day One Biopharmaceuticals, Inc. (DAWN) Reports Q4 Loss, Beats Revenue Estimates (Zacks)
Jan-05-26 07:00AM	Gyre Therapeutics Announces Alignment with China's CDE on Conditional Approval Pathway and Priority Review Eligibility for Hydronidone Following Pre-NDA Meeting (GlobeNewswire) +16.30%
Nov-07-25 07:10AM	Gyre Therapeutics, Inc. (GYRE) Q3 Earnings Surpass Estimates (Zacks)
06:00AM	Gyre Therapeutics Reports Third Quarter 2025 and Year-to-Date Financial Results and Provides Business Update (GlobeNewswire)
Oct-29-25 06:05PM	Guardant Health (GH) Reports Q3 Loss, Beats Revenue Estimates (Zacks)
Oct-17-25 05:29AM	New Strong Sell Stocks for Oct. 17th (Zacks) -5.03%
Oct-15-25 07:00AM	Gyre Therapeutics Announces Completion of Patient Enrollment in Phase 3 Clinical Trial of Pirfenidone Capsules for the Treatment of Pneumoconiosis (GlobeNewswire) +10.74%
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Oct-14-25 07:00AM	Gyre Therapeutics to Present Results from Positive Phase 3 Clinical Trial Evaluating Hydronidone for the Treatment of Liver Fibrosis in Chronic Hepatitis B at AASLD-The Liver Meeting 2025 (GlobeNewswire)
Oct-09-25 10:13AM	Strength Seen in Septerna, Inc. (SEPN): Can Its 7.0% Jump Turn into More Strength? (Zacks)
Sep-05-25 04:05PM	Gyre Therapeutics to Present at the H.C. Wainwright 27th Annual Global Investment Conference (GlobeNewswire)
Aug-22-25 07:00AM	Gyre Therapeutics Announces the Appointment of Dan Weng, M.D., to Board of Directors (GlobeNewswire) +8.34%
Aug-11-25 04:01PM	Gyre Therapeutics Reports Second Quarter 2025 and Year-to-Date Financial Results and Provides Business and Leadership Update (GlobeNewswire) +6.93%
Aug-07-25 05:10PM	Arcellx, Inc. (ACLX) Reports Q2 Loss, Misses Revenue Estimates (Zacks)
Aug-04-25 05:50PM	Prothena (PRTA) Reports Q2 Loss, Lags Revenue Estimates (Zacks) +5.56%
Jun-10-25 07:00AM	Gyre Therapeutics Announces First Dosing in Phase 1 Trial of F230 for Pulmonary Arterial Hypertension in China (GlobeNewswire) +5.88%
May-29-25 11:34PM	Gyre Therapeutics, Inc. (GYRE) Raises $23M in Public Stock Offering to Fund Liver Fibrosis Trials (Insider Monkey)
04:01PM	Gyre Therapeutics Announces Closing of its Public Offering and Full Exercise of Underwriters' Option to Purchase Additional Shares (GlobeNewswire)
May-22-25 08:57PM	Gyre Therapeutics Announces Pricing of $20.0 Million Public Offering of Common Stock (GlobeNewswire) +8.10% -22.57%
04:02PM	Gyre Therapeutics Announces Proposed Underwritten Public Offering of Common Stock (GlobeNewswire)
04:01PM	Gyre Therapeutics' Hydronidone Met the Primary Endpoint and Demonstrated Statistically Significant Fibrosis Regression in Pivotal Phase 3 Trial for the Treatment of CHB-associated Liver Fibrosis in China (GlobeNewswire)
May-09-25 06:00AM	Gyre Therapeutics Reports First Quarter 2025 Financial Results and Provides Business Update (GlobeNewswire)
May-07-25 09:15AM	Clene Inc. (CLNN) Reports Q1 Loss, Lags Revenue Estimates (Zacks)
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May-01-25 08:25AM	Blueprint Medicines (BPMC) Reports Q1 Loss, Lags Revenue Estimates (Zacks)
Mar-31-25 07:00AM	Gyre Therapeutics Announces NMPA Approval for Clinical Trial Evaluating Pirfenidone Capsules in Oncology-Related Pulmonary Complications (GlobeNewswire) -15.26%
Mar-27-25 07:00AM	Gyre Therapeutics Announces Publication of Protocol for Phase 3 Trial Evaluating F351 for CHB-Associated Liver Fibrosis in Journal of Clinical and Translational Hepatology (GlobeNewswire)
Mar-21-25 09:14AM	Gyre: Intriguing Upcoming Data Catalyst, But I'm Still On Sidelines (SeekingAlpha)
Mar-17-25 04:15PM	Gyre Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update (GlobeNewswire) -30.21%
Jan-06-25 07:00AM	Gyre Therapeutics Announces the Appointment of Ping Zhang to Board of Directors (GlobeNewswire) -9.82%
Nov-13-24 06:00AM	Gyre Therapeutics Reports Third Quarter 2024 and Year-To-Date Financial Results and Provides Business Update (GlobeNewswire) -9.56%
Oct-22-24 04:05PM	Gyre Therapeutics Announces Last Patient Completed Pivotal Phase 3 Trial Evaluating F351 for CHB-Associated Liver Fibrosis (GlobeNewswire)
Oct-01-24 04:05PM	Gyre Therapeutics to Present at 8th Annual H.C. Wainwright MASH Investor Conference (GlobeNewswire)
Sep-04-24 04:05PM	Gyre Therapeutics to Present at H.C. Wainwright 26th Annual Global Investment Conference (GlobeNewswire)
Aug-13-24 06:00AM	Gyre Therapeutics Reports Second Quarter 2024 and Year-To-Date Financial Results and Provides Business Update (GlobeNewswire)
Aug-09-24 07:00AM	Gyre Therapeutics to Present at Sidoti Virtual Investor Conference (GlobeNewswire)
Aug-08-24 04:05PM	Gyre Therapeutics Announces Appointment of David M. Epstein, Ph.D., to Board of Directors (GlobeNewswire)
Jul-02-24 04:05PM	Gyre Therapeutics Announces China's NMPA Approval of Avatrombopag Maleate Tablets for the Treatment of CLD-Associated Thrombocytopenia (GlobeNewswire)
Jun-18-24 04:05PM	Gyre Therapeutics Announces Publication in Journal of Gastroenterology and Hepatology (GlobeNewswire) -6.33%
May-30-24 04:05PM	Gyre Pharmaceuticals Receives IND Approval from China's NMPA to Evaluate F230 for the Treatment of Pulmonary Arterial Hypertension (GlobeNewswire) +9.13%
May-28-24 04:05PM	Gyre Therapeutics Announces Expected Addition to the Russell 2000 and Russell 3000 Indexes (GlobeNewswire) -15.35%
May-09-24 04:10PM	Gyre Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
Mar-28-24 05:32AM	Gyre Therapeutics Inc (GYRE) Announces Full Year 2023 Financial Outcomes and Business Progress (GuruFocus.com)
Mar-26-24 06:32AM	Gyre Therapeutics Posts Loss In 2023 (RTT News)
06:00AM	Gyre Therapeutics Reports Full Year 2023 Financial Results and Provides Business Update (GlobeNewswire)
Mar-21-24 07:00AM	Gyre Therapeutics Expands Board of Directors with Appointment of Rodney L. Nussbaum (GlobeNewswire)
Dec-15-23 09:04AM	Totus Medicines Announces Appointment of Nassim Usman, Ph.D., as President & CEO and the Closing of a $66M Series B Funding (PR Newswire) +9.91%
Nov-13-23 07:00AM	Gyre Therapeutics Presents Poster at the American Association for the Study of Liver Diseases (AASLD) Annual Liver Meeting (GlobeNewswire)
Oct-30-23 12:00PM	Catalyst Biosciences Announces Completion of Business Combination With Beijing Continent Pharmaceuticals and Implementation of Name Change and Reverse Stock Split (GlobeNewswire)
Aug-23-23 12:36PM	Is Catalyst Biosciences (CBIO) Significantly Overvalued? (GuruFocus.com) +11.72%
Apr-03-23 09:01AM	Catalyst Biosciences, Inc. (NASDAQ:CBIO) insiders placed bullish bets worth US$941k in the last 12 months (Simply Wall St.)
Mar-29-23 10:13AM	12 Cheap Healthcare Stocks to Buy in 2023 (Insider Monkey)
Feb-28-23 08:00AM	Catalyst Biosciences Provides Corporate Update (GlobeNewswire) +23.75%
Dec-27-22 07:00AM	Catalyst Biosciences Completes First Steps in Reverse Merger Plan (GlobeNewswire)
Nov-16-22 05:05AM	Catalyst Biosciences Third Quarter 2022 Earnings: US$0.15 loss per share (vs US$0.80 loss in 3Q 2021) (Simply Wall St.)
Sep-19-22 09:43AM	Bullish insiders at Catalyst Biosciences, Inc. (NASDAQ:CBIO) loaded up on US$1.2m of stock earlier this year (Simply Wall St.)
Sep-01-22 04:05PM	Catalyst Biosciences, Inc. Announces September 21, 2022 as the Ex-Dividend Date for Special Cash Dividend of $1.43 per share (GlobeNewswire)
Aug-25-22 08:00AM	Catalyst Biosciences, Inc. Declares Special Cash Dividend of $1.43 per share (GlobeNewswire)
Aug-23-22 07:11AM	Catalyst Biosciences (NASDAQ:CBIO) investors are sitting on a loss of 71% if they invested three years ago (Simply Wall St.)
Aug-19-22 08:00AM	Catalyst Biosciences, Inc. Announces Dismissal of JDS1 Litigation (GlobeNewswire)
Aug-15-22 04:05PM	Catalyst Biosciences Reports Second Quarter 2022 Operating & Financial Results (GlobeNewswire)
Aug-11-22 06:00AM	JDS1, LLC Terminates Proxy Contest at Catalysts 2022 Annual Meeting (Business Wire)
Aug-10-22 12:46PM	Catalyst Biosciences Announces Withdrawal of JDS1 Nominations to the Board (GlobeNewswire)
Aug-03-22 08:00AM	Leading Independent Proxy Advisory Firms ISS and Glass Lewis Recommend Catalyst Stockholders Vote FOR All of the Companys Nominees on the WHITE Proxy Card (GlobeNewswire)
Aug-01-22 08:30AM	Catalyst Biosciences Publishes New Investor Presentation (GlobeNewswire)
07:30AM	Catalyst Biosciences Announces Support from Largest Single Stockholder (GlobeNewswire)
Jul-22-22 12:21PM	JDS1, LLC Files Definitive Proxy Statement and Sends Letter to Catalyst Stockholders (Business Wire)
Jul-19-22 08:00AM	Catalyst Biosciences Sends Letter to Stockholders (GlobeNewswire)
Jul-14-22 09:40AM	Has Adicet Bio (ACET) Outpaced Other Medical Stocks This Year? (Zacks)
Jul-06-22 08:00AM	Catalyst Biosciences Comments on Favorable Delaware Court of Chancery Ruling (GlobeNewswire)
Jun-29-22 08:00AM	Catalyst Biosciences Announces Plan to Distribute Cash to Stockholders (GlobeNewswire) +13.25%
Jun-28-22 09:40AM	Has Catalyst Biosciences (CBIO) Outpaced Other Medical Stocks This Year? (Zacks) -5.03%
May-26-22 11:03AM	The Petri Dish: NIH gives $68M to Pfizer-partnered AI startup (American City Business Journals) -22.38%
May-23-22 09:57AM	Catalyst Biosciences Stock More Than Doubles After Assets Sale To Vertex (Benzinga) +234.21%
08:30AM	Catalyst Biosciences Sells Complement Portfolio for $60 Million (GlobeNewswire)
May-09-22 08:30AM	Catalyst Biosciences Reports First Quarter 2022 Operating & Financial Results (GlobeNewswire) -11.42%
Apr-08-22 09:57AM	Here's Why Catalyst Biosciences (NASDAQ:CBIO) Must Use Its Cash Wisely (Simply Wall St.) -7.26%
Mar-31-22 08:00AM	Catalyst Biosciences Reports Fourth Quarter and Year-end 2021 Operating & Financial Results and Provides a Corporate Update (GlobeNewswire)
Mar-15-22 05:00PM	Catalyst Biosciences Regains Rights to CB 2782-PEG for the Treatment of Dry AMD Expands CBIOs Complement Portfolio in Ophthalmology (GlobeNewswire) +9.50%
Feb-17-22 08:00AM	Catalyst Biosciences Engages Perella Weinberg Partners to Assist the Company in Exploring Strategic Alternatives (GlobeNewswire) +6.40%
Feb-03-22 05:38PM	Kalos Management, Inc. Buys Vale SA, Sells Consensus Cloud Solutions Inc, Intuitive Surgical ... (GuruFocus.com)
Jan-25-22 08:00AM	Catalyst Biosciences Receives Rare Pediatric Disease Designation for CB 4332 for the Treatment of CFI Deficiency (GlobeNewswire) -7.05%
Jan-12-22 12:00PM	Catalyst Biosciences, Inc. (CBIO) Upgraded to Buy: Here's What You Should Know (Zacks)
Dec-20-21 07:51PM	Penny Stocks to Buy Using Technical Analysis for January 2022 (Investopedia)
Dec-11-21 11:59AM	Timothy P. Lynchs Stonepine Capital Portfolio: Top 10 Healthcare Stocks (Insider Monkey)
Nov-22-21 08:00AM	Catalyst Biosciences to Present at the Piper Sandler 33rd Annual Virtual Healthcare Conference (GlobeNewswire)
Nov-12-21 09:54AM	Catalyst Biosciences Down 40% After Announcing MarzAA Development Halt (Investing.com) -41.84%
09:24AM	What Is Happening With Catalyst Biosciences Shares Today? (Benzinga)
07:00AM	Catalyst Biosciences Announces Change in Corporate Strategy (GlobeNewswire)
Oct-29-21 08:00AM	Catalyst Biosciences Announces CFI Variant Presentations at Two Upcoming Scientific Conferences (GlobeNewswire)
Oct-28-21 03:05PM	Catalyst Biosciences, Inc. (CBIO) May Report Negative Earnings: Know the Trend Ahead of Q3 Release (Zacks) +5.03%
Oct-13-21 04:05PM	Catalyst Biosciences Announces Chief Financial Officer Transition (GlobeNewswire)
Sep-28-21 04:01PM	FDA Grants Catalyst Biosciences Orphan Drug Designation for MarzAA for the Treatment of Factor VII Deficiency (GlobeNewswire) -8.44%
Sep-24-21 08:00AM	Catalyst Biosciences to Present at the Cantor Global Healthcare Conference (GlobeNewswire)

Gyre Therapeutics, Inc. operates as a biopharmaceutical company. It is focused on the development and commercialization of Hydronidone (F351) for the treatment of Metabolic Dysfunction Associated Steatohepatitis (MASH-associated liver fibrosis). The firm operates through the BC and Gyre segments. The company was founded on March 7, 1997 and is headquartered in San Diego, CA.

Chief Financial OfficerMr. Thomas W. Eastling M.D.

Chief Operating OfficerMr. Weiguo Ye

CEODr. Ying Luo Ph.D.

Chief Scientific OfficerDr. Yue Xiong Ph.D.

General Counsel & Corporate SecretaryMr. Joshua Bergmann J.D.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Ye Weiguo	Chief Operating Officer	May 26 '26	Option Exercise	0.75	4,000	3,000	704,000	May 27 04:01 PM
Ye Weiguo	Chief Operating Officer	May 22 '26	Option Exercise	0.75	3,500	2,625	703,500	May 27 04:01 PM
Ye Weiguo	Chief Operating Officer	May 26 '26	Sale	6.10	4,000	24,400	700,000	May 27 04:01 PM
Ye Weiguo	Chief Operating Officer	May 22 '26	Sale	6.08	3,500	21,280	700,000	May 27 04:01 PM
Ye Weiguo	Chief Operating Officer	May 21 '26	Option Exercise	0.75	12,820	9,615	712,820	May 22 06:19 PM
Ye Weiguo	Chief Operating Officer	May 20 '26	Option Exercise	0.75	9,400	7,050	709,400	May 22 06:19 PM
Ye Weiguo	Chief Operating Officer	May 21 '26	Sale	6.15	12,820	78,843	700,000	May 22 06:19 PM
Ye Weiguo	Chief Operating Officer	May 20 '26	Sale	6.15	9,400	57,810	700,000	May 22 06:19 PM
Ye Weiguo	Chief Operating Officer	May 19 '26	Option Exercise	0.75	9,120	6,840	709,120	May 20 04:01 PM
Ye Weiguo	Chief Operating Officer	May 18 '26	Option Exercise	0.75	200	150	700,200	May 20 04:01 PM
Ye Weiguo	Chief Operating Officer	May 19 '26	Sale	6.37	9,120	58,094	700,000	May 20 04:01 PM
Ye Weiguo	Chief Operating Officer	May 18 '26	Sale	6.62	200	1,324	700,000	May 20 04:01 PM
Ye Weiguo	Chief Operating Officer	May 14 '26	Option Exercise	0.75	15,580	11,685	715,580	May 18 04:01 PM
Ye Weiguo	Chief Operating Officer	May 15 '26	Option Exercise	0.75	13,100	9,825	713,100	May 18 04:01 PM
Ye Weiguo	Chief Operating Officer	May 14 '26	Sale	6.91	15,580	107,658	700,000	May 18 04:01 PM
Ye Weiguo	Chief Operating Officer	May 15 '26	Sale	6.65	13,100	87,115	700,000	May 18 04:01 PM
Ye Weiguo	Officer	May 13 '26	Proposed Sale	7.07	300,000	2,121,000		May 11 07:10 AM
Luo Ying	Chief Executive Officer	May 06 '26	Sale	8.04	10,136	81,493	2,565,226	May 07 09:58 PM
Luo Ying	Chief Executive Officer	May 05 '26	Sale	8.01	179	1,434	2,575,362	May 07 09:58 PM
Ye Weiguo	Officer	Nov 15 '25	Proposed Sale	8.34	548,000	4,570,320		Nov 13 08:32 PM

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GYRE

Gyre Therapeutics Inc

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