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Ticker Owner Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
AFIBORBIMED ADVISORS LLCDirectorJul 19Buy14.001,071,42814,999,9924,872,025Jul 21 05:30 PM
IMRAORBIMED ADVISORS LLCDirectorJul 16Buy6.001,666,6669,999,9961,666,666Jul 16 04:27 PM
SWTXORBIMED ADVISORS LLC10% OwnerJul 01Sale85.0115,9591,356,6756,028,307Jul 06 04:42 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 28Sale85.176,502553,7756,044,266Jun 30 09:01 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 23Sale85.001008,5006,107,302Jun 25 07:11 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 24Sale85.2234,2002,914,5246,073,102Jun 25 07:11 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 25Sale85.1422,3341,901,5176,050,768Jun 25 07:11 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 10Sale85.0930,8522,625,1976,107,402Jun 14 05:58 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 07Sale84.9037131,4986,185,936Jun 09 06:26 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 08Sale85.3742,6333,639,5796,143,303Jun 09 06:26 PM
SWTXORBIMED ADVISORS LLC10% OwnerJun 09Sale85.335,049430,8316,138,254Jun 09 06:26 PM
NPCEORBIMED ADVISORS LLC10% OwnerApr 21Buy17.00235,0003,995,000235,000Apr 23 08:32 PM
EWTXORBIMED ADVISORS LLCDirectorMar 30Buy16.00359,3755,750,00013,359,456Mar 31 07:10 PM
ORICORBIMED ADVISORS LLCDirectorMar 29Sale23.3175,5551,761,1872,240,440Mar 31 05:08 PM
ORICORBIMED ADVISORS LLCDirectorMar 30Sale23.9327,869666,9052,212,571Mar 31 05:08 PM
ORICORBIMED ADVISORS LLCDirectorMar 24Sale24.8032,959817,3832,395,334Mar 26 05:51 PM
ORICORBIMED ADVISORS LLCDirectorMar 25Sale24.7051,5231,272,6182,343,811Mar 26 05:51 PM
ORICORBIMED ADVISORS LLCDirectorMar 26Sale23.8827,816664,2462,315,995Mar 26 05:51 PM
ORICORBIMED ADVISORS LLCDirectorMar 19Sale26.4721,275563,1492,439,958Mar 23 05:22 PM
ORICORBIMED ADVISORS LLCDirectorMar 22Sale26.477,673203,1042,432,285Mar 23 05:22 PM
ORICORBIMED ADVISORS LLCDirectorMar 23Sale24.323,99297,0852,428,293Mar 23 05:22 PM
ORICORBIMED ADVISORS LLCDirectorMar 16Sale27.7241,3531,146,3052,486,082Mar 18 09:07 PM
ORICORBIMED ADVISORS LLCDirectorMar 17Sale28.4318,790534,2002,467,292Mar 18 09:07 PM
ORICORBIMED ADVISORS LLCDirectorMar 18Sale28.036,059169,8342,461,233Mar 18 09:07 PM
ORICORBIMED ADVISORS LLCDirectorMar 11Sale33.0458,5511,934,5252,707,166Mar 15 08:55 PM
ORICORBIMED ADVISORS LLCDirectorMar 12Sale30.2990,5212,741,8812,616,645Mar 15 08:55 PM
ORICORBIMED ADVISORS LLCDirectorMar 15Sale29.1489,2102,599,5792,527,435Mar 15 08:55 PM
SWTXORBIMED ADVISORS LLC10% OwnerMar 01Sale83.191,220,000101,491,8006,186,307Mar 03 06:55 PM
DBTXORBIMED ADVISORS LLCDirectorFeb 17Buy18.001,666,66629,999,9883,843,206Feb 19 07:09 PM
CRVSORBIMED ADVISORS LLCDirectorFeb 17Buy3.501,285,7144,499,9998,053,298Feb 19 04:52 PM
TERNORBIMED ADVISORS LLCDirectorFeb 09Buy17.00475,0008,075,0002,274,723Feb 09 03:09 PM
CTICORBIMED ADVISORS LLC10% OwnerJan 07Sale3.502,000,0007,000,0007,520,600Jan 11 04:46 PM
ALPNORBIMED ADVISORS LLCDirectorDec 28Sale14.25600,0008,550,0003,070,955Dec 30 04:44 PM
ARPOORBIMED ADVISORS LLC10% OwnerDec 08Sale1.9621,40041,9440Dec 10 05:04 PM
SBTXORBIMED ADVISORS LLCDirectorDec 08Buy21.001,190,47725,000,017952,377Dec 08 08:41 PM
ARQTORBIMED ADVISORS LLCDirectorOct 02Buy25.00496,00012,400,0004,267,564Oct 06 05:27 PM
LOGCORBIMED ADVISORS LLCDirectorOct 01Buy6.001,481,4828,888,8924,126,972Oct 05 05:36 PM
ETNBORBIMED ADVISORS LLCDirectorSep 21Sale28.00275,0007,700,0001,864,721Sep 23 05:09 PM
INSPORBIMED ADVISORS LLCDirectorAug 17Sale107.4994,90010,200,80143,543Aug 19 05:24 PM
INSPORBIMED ADVISORS LLCDirectorAug 18Sale108.5443,5434,726,1570Aug 19 05:24 PM
INSPORBIMED ADVISORS LLCDirectorAug 12Sale107.4542,6794,585,859187,751Aug 14 05:19 PM
INSPORBIMED ADVISORS LLCDirectorAug 13Sale109.9329,2513,215,562158,500Aug 14 05:19 PM
INSPORBIMED ADVISORS LLCDirectorAug 14Sale109.0320,2572,208,621138,443Aug 14 05:19 PM
INSPORBIMED ADVISORS LLCDirectorAug 07Sale106.1828,9933,078,477318,007Aug 11 06:23 PM
INSPORBIMED ADVISORS LLCDirectorAug 10Sale105.2347,7005,019,471270,307Aug 11 06:23 PM
INSPORBIMED ADVISORS LLCDirectorAug 11Sale105.7839,8774,218,189230,430Aug 11 06:23 PM
SCPHORBIMED ADVISORS LLC10% OwnerMay 21Buy8.651,387,28311,999,9984,565,948May 26 04:44 PM
ALECORBIMED ADVISORS LLC10% OwnerApr 14Sale23.5223,231546,3931,921,804Apr 16 08:23 PM
ALECORBIMED ADVISORS LLC10% OwnerApr 16Sale23.5362,1831,463,1661,906,718Apr 16 08:23 PM
ALECORBIMED ADVISORS LLC10% OwnerApr 07Sale23.109,170211,8272,017,374Apr 09 05:30 PM
ALECORBIMED ADVISORS LLC10% OwnerApr 08Sale23.6582,6141,953,8211,997,333Apr 09 05:30 PM
ALECORBIMED ADVISORS LLC10% OwnerApr 09Sale23.79288,1016,853,9231,927,440Apr 09 05:30 PM
ALECORBIMED ADVISORS LLC10% OwnerMar 31Sale24.50250,0006,125,0002,019,598Apr 02 05:06 PM
ALECORBIMED ADVISORS LLC10% OwnerMar 23Sale26.0514,598380,2782,110,336Mar 25 05:54 PM
ALECORBIMED ADVISORS LLC10% OwnerMar 24Sale24.4567,6441,653,8962,093,927Mar 25 05:54 PM
ALECORBIMED ADVISORS LLC10% OwnerMar 25Sale24.6656,4111,391,0952,080,243Mar 25 05:54 PM
INSPORBIMED ADVISORS LLCDirectorMar 06Sale83.52500,00041,760,000347,000Mar 10 05:06 PM
INSPORBIMED ADVISORS LLCDirectorMar 03Sale84.25500,00042,122,500847,000Mar 05 06:34 PM
ALECORBIMED ADVISORS LLC10% OwnerMar 02Sale26.001,874,20348,729,2780Mar 04 04:17 PM
ALECORBIMED ADVISORS LLC10% OwnerJan 09Sale19.50379,9977,409,94238,808Jan 13 04:48 PM
ALECORBIMED ADVISORS LLC10% OwnerDec 20Sale19.66342,5006,733,55059,800Dec 26 04:54 PM
ALECORBIMED ADVISORS LLC10% OwnerDec 23Sale19.8294,2851,868,72949,400Dec 26 04:54 PM
ALECORBIMED ADVISORS LLC10% OwnerDec 24Sale19.5971,8001,406,56241,400Dec 26 04:54 PM
ALECORBIMED ADVISORS LLC10% OwnerDec 26Sale18.6010,800200,88040,200Dec 26 04:54 PM
ALECORBIMED ADVISORS LLC10% OwnerDec 17Sale18.52954,10017,669,93297,700Dec 19 04:33 PM
TCDAORBIMED ADVISORS LLCDirectorDec 11Sale40.001,500,00060,000,0009,614,280Dec 12 05:20 PM
INSPORBIMED ADVISORS LLCDirectorNov 26Sale69.9970,6134,941,9261,401,713Nov 29 11:56 AM
INSPORBIMED ADVISORS LLCDirectorNov 27Sale71.6353,3873,823,9901,348,326Nov 29 11:56 AM
CRVSORBIMED ADVISORS LLCDirectorAug 06Buy3.51142,656500,7236,767,584Aug 08 04:59 PM
CRVSORBIMED ADVISORS LLCDirectorJun 27Buy3.3432,923109,9636,000,507Jul 01 06:15 PM
CRVSORBIMED ADVISORS LLCDirectorJun 28Buy3.72565,1782,102,4626,565,685Jul 01 06:15 PM
CRVSORBIMED ADVISORS LLCDirectorJul 01Buy3.9159,243231,6406,624,928Jul 01 06:15 PM
ADAPORBIMED ADVISORS LLCDirectorJun 04Sale13.5717,100232,0474,902,910Jun 06 06:10 PM
ADAPORBIMED ADVISORS LLCDirectorJun 06Sale13.491,60021,5844,901,310Jun 06 06:10 PM
ADAPORBIMED ADVISORS LLCDirectorMay 30Sale13.52121,0001,635,9204,970,010Jun 01 05:25 PM
ADAPORBIMED ADVISORS LLCDirectorJun 01Sale13.4950,000674,5004,920,010Jun 01 05:25 PM
ADAPORBIMED ADVISORS LLCDirectorMay 14Sale13.5010,300139,0505,091,010May 16 05:22 PM
PIRSORBIMED ADVISORS LLC10% OwnerApr 30Sale6.351,000,0006,350,00038,870May 02 05:13 PM
ADAPORBIMED ADVISORS LLCDirectorMar 27Sale11.501,016,08411,684,9665,133,293Mar 29 06:54 PM
ADAPORBIMED ADVISORS LLCDirectorMar 29Sale11.5331,983368,7645,101,310Mar 29 06:54 PM
CRVSORBIMED ADVISORS LLCDirectorMar 12Buy8.50588,2354,999,9985,967,584Mar 14 01:58 PM
GKOSORBIMED ADVISORS LLCDirectorMar 02Sale32.29464,58315,002,2193,511Mar 06 07:36 PM
GKOSORBIMED ADVISORS LLCDirectorMar 05Sale32.44210,5966,831,6991,523Mar 06 07:36 PM
GKOSORBIMED ADVISORS LLCDirectorMar 06Sale30.70161,3214,953,2740Mar 06 07:36 PM
XTNTORBIMED ADVISORS LLCDirectorFeb 14Buy7.20945,8196,809,8975,890,884Feb 23 06:55 PM
PIRSORBIMED ADVISORS LLC10% OwnerFeb 13Option Exercise4.777,89737,6715,508,552Feb 15 04:57 PM
PIRSORBIMED ADVISORS LLC10% OwnerFeb 13Sale8.987,89770,91549,270Feb 15 04:57 PM
KALAORBIMED ADVISORS LLC10% OwnerFeb 08Buy12.9325,000323,2503,447,840Feb 12 04:35 PM
KALAORBIMED ADVISORS LLC10% OwnerFeb 02Buy14.7337,840557,3833,422,840Feb 06 05:05 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 31Buy15.00339,4005,091,0003,362,160Feb 02 05:45 PM
KALAORBIMED ADVISORS LLC10% OwnerFeb 01Buy14.9922,840342,3723,385,000Feb 02 05:45 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 26Buy14.9322,760339,8072,972,760Jan 30 03:34 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 29Buy14.9950,000749,5003,022,760Jan 30 03:34 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 12Buy14.5038,354556,1332,731,069Jan 24 08:59 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 19Buy14.9574,9311,120,2182,806,000Jan 24 08:59 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 22Buy14.9875,0001,123,5002,881,000Jan 24 08:59 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 23Buy14.994,36365,4012,885,363Jan 24 08:59 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 24Buy14.9164,637963,7382,950,000Jan 24 08:59 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 10Buy12.83170,3382,185,4372,622,569Jan 12 05:29 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 11Buy13.6541,700569,2052,664,269Jan 12 05:29 PM
KALAORBIMED ADVISORS LLC10% OwnerJan 12Buy15.4028,446438,0682,692,715Jan 12 05:29 PM
PIRSORBIMED ADVISORS LLC10% OwnerJan 03Sale7.351,709,62012,565,70749,270Jan 04 03:23 PM
PIRSORBIMED ADVISORS LLC10% OwnerDec 18Option Exercise2.09147,635308,0527,340,465Dec 20 05:12 PM
PIRSORBIMED ADVISORS LLC10% OwnerDec 18Sale5.70147,635841,52065,398Dec 20 05:12 PM
GKOSORBIMED ADVISORS LLCDirectorAug 31Sale37.8244,9221,698,95012,945Sep 05 09:27 PM
GKOSORBIMED ADVISORS LLCDirectorSep 01Sale37.72110,0784,152,14211,907Sep 05 09:27 PM
GKOSORBIMED ADVISORS LLCDirectorSep 05Sale39.09425,20016,621,7307,895Sep 05 09:27 PM
GKOSORBIMED ADVISORS LLCDirectorAug 15Sale38.2932,5001,244,42516,128Aug 17 05:20 PM
GKOSORBIMED ADVISORS LLCDirectorAug 16Sale38.0165,5802,492,69615,509Aug 17 05:20 PM
GKOSORBIMED ADVISORS LLCDirectorAug 17Sale37.85226,9208,588,92213,369Aug 17 05:20 PM
ADAPORBIMED ADVISORS LLCDirectorMar 27Buy4.201,190,4764,999,9996,149,377Mar 28 06:48 PM
GKOSORBIMED ADVISORS LLCDirectorMar 10Sale45.9897,0284,461,34719,129Mar 14 07:39 PM
GKOSORBIMED ADVISORS LLCDirectorMar 13Sale45.30211,4109,577,45417,134Mar 14 07:39 PM
GKOSORBIMED ADVISORS LLCDirectorMar 14Sale44.5474,1003,300,41416,435Mar 14 07:39 PM
GKOSORBIMED ADVISORS LLCDirectorMar 03Sale47.0555,7722,624,07320,044Mar 07 06:48 PM
AGLEORBIMED ADVISORS LLC10% OwnerFeb 16Buy5.0430,500153,7201,390,724Feb 21 05:58 PM
AGLEORBIMED ADVISORS LLC10% OwnerFeb 17Buy5.1971,800372,6421,462,524Feb 21 05:58 PM
AGLEORBIMED ADVISORS LLC10% OwnerFeb 21Buy5.367,00037,5201,469,524Feb 21 05:58 PM
OTICORBIMED ADVISORS LLCDirectorNov 25Sale28.9134,8001,006,0681,882,400Nov 30 06:55 PM
OTICORBIMED ADVISORS LLCDirectorNov 27Sale28.9729,000840,1301,853,400Nov 30 06:55 PM
OTICORBIMED ADVISORS LLCDirectorNov 30Sale28.743,30695,0261,850,094Nov 30 06:55 PM
OTICORBIMED ADVISORS LLCDirectorNov 20Sale28.5983,9002,398,7012,034,100Nov 24 08:31 PM
OTICORBIMED ADVISORS LLCDirectorNov 23Sale28.4580,8002,298,7601,953,300Nov 24 08:31 PM
OTICORBIMED ADVISORS LLCDirectorNov 24Sale28.7536,1001,037,8751,917,200Nov 24 08:31 PM
OTICORBIMED ADVISORS LLCDirectorNov 17Sale28.8111,098319,6802,245,300Nov 19 08:39 PM
OTICORBIMED ADVISORS LLCDirectorNov 19Sale28.60127,3003,640,7802,118,000Nov 19 08:39 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 12Sale5.98287,8911,721,58817,100Oct 13 04:01 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 07Sale7.3653,900396,70425,763Oct 09 07:49 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 08Sale7.24400,0002,896,00021,926Oct 09 07:49 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 09Sale7.03212,7091,495,34419,885Oct 09 07:49 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 02Sale10.3447,900495,28627,439Oct 06 07:34 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 05Sale8.19138,1001,131,03926,276Oct 06 07:34 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 06Sale7.807,00054,60026,217Oct 06 07:34 PM
SIENORBIMED ADVISORS LLC10% OwnerSep 29Sale10.0810,558106,42528,611Oct 01 05:55 PM
SIENORBIMED ADVISORS LLC10% OwnerSep 30Sale10.1743,840445,85328,242Oct 01 05:55 PM
SIENORBIMED ADVISORS LLC10% OwnerOct 01Sale10.3447,500491,15027,842Oct 01 05:55 PM
SIENORBIMED ADVISORS LLC10% OwnerSep 24Sale11.008,30691,35929,900Sep 28 09:14 PM
SIENORBIMED ADVISORS LLC10% OwnerSep 25Sale10.58132,0001,396,04028,789Sep 28 09:14 PM
SIENORBIMED ADVISORS LLC10% OwnerSep 28Sale10.3010,602109,20128,700Sep 28 09:14 PM
ICPTORBIMED ADVISORS LLCDirectorMar 26Sale286.75157,20045,076,4421,120,324Mar 30 03:58 PM
ICPTORBIMED ADVISORS LLCDirectorMar 23Sale275.18159,40043,863,0671,325,924Mar 25 07:28 PM
ICPTORBIMED ADVISORS LLCDirectorMar 24Sale272.0045,60012,402,9951,280,324Mar 25 07:28 PM
ICPTORBIMED ADVISORS LLCDirectorMar 25Sale270.232,800756,6441,277,524Mar 25 07:28 PM
MRTXORBIMED ADVISORS LLC10% OwnerFeb 03Buy20.00100,0002,000,0001,267,000Feb 05 05:26 PM
ICPTORBIMED ADVISORS LLCDirectorAug 25Sale295.5950,00014,779,4991,546,582Aug 27 09:05 PM
ICPTORBIMED ADVISORS LLCDirectorAug 26Sale300.0761,25818,381,5881,485,324Aug 27 09:05 PM
ICPTORBIMED ADVISORS LLCDirectorAug 14Sale299.8260,00017,989,2071,596,582Aug 18 09:07 PM
ICPTORBIMED ADVISORS LLCDirectorApr 09Sale320.0081,30526,017,6001,654,603Apr 11 05:27 PM
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