 |
|
| Ticker |
Owner |
Relationship |
Date |
Transaction |
Cost  |
#Shares |
Value ($) |
#Shares Total |
SEC Form 4 |
| TLIS | BAKER BROS. ADVISORS LP | Director | Feb 17 | Buy | 16.00 | 6,250,000 | 100,000,000 | 7,003,176 | Feb 19 06:17 PM | | PRLD | BAKER BROS. ADVISORS LP | Director | Jan 27 | Option Exercise | 12.85 | 10,376 | 133,332 | 9,252,951 | Jan 29 07:04 PM | | IGMS | BAKER BROS. ADVISORS LP | Director | Jan 27 | Option Exercise | 28.63 | 22,420 | 641,854 | 2,895,306 | Jan 29 07:03 PM | | BGNE | BAKER BROS. ADVISORS LP | Director | Jan 04 | Sale | 220.50 | 121,154 | 26,714,457 | 968,943 | Jan 06 06:32 PM | | NLTX | BAKER BROS. ADVISORS LP | Director | Jul 07 | Buy | 15.25 | 424,000 | 6,466,000 | 3,501,691 | Dec 23 07:31 PM | | BGNE | BAKER BROS. ADVISORS LP | Director | Dec 04 | Sale | 220.50 | 1,511,546 | 333,295,893 | 979,003 | Dec 04 05:24 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 25 | Buy | 56.65 | 48,125 | 2,726,182 | 11,324,937 | Sep 25 06:02 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 22 | Buy | 50.67 | 74,958 | 3,797,911 | 11,160,400 | Sep 24 07:30 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 23 | Buy | 52.43 | 92,069 | 4,826,756 | 11,246,368 | Sep 24 07:30 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 24 | Buy | 52.02 | 36,020 | 1,873,924 | 11,280,001 | Sep 24 07:30 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 03 | Buy | 47.97 | 123,883 | 5,942,904 | 10,905,982 | Sep 08 05:58 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 04 | Buy | 46.73 | 82,801 | 3,869,473 | 10,982,772 | Sep 08 05:58 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Sep 08 | Buy | 47.34 | 116,295 | 5,505,934 | 11,090,409 | Sep 08 05:58 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Aug 19 | Buy | 46.99 | 3,869 | 181,791 | 10,606,135 | Aug 21 05:19 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Aug 20 | Buy | 47.40 | 60,573 | 2,871,156 | 10,662,260 | Aug 21 05:19 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Aug 21 | Buy | 48.63 | 139,044 | 6,762,056 | 10,791,092 | Aug 21 05:19 PM | | INCY | BAKER BROS. ADVISORS LP | Director | May 28 | Buy | 102.55 | 2 | 205 | 29,313,198 | May 28 08:07 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 15 | Sale | 160.00 | 1,750,000 | 280,000,000 | 4,082,851 | May 19 06:03 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 06 | Sale | 165.05 | 390,072 | 64,379,473 | 4,286,935 | May 08 05:47 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 07 | Sale | 164.41 | 168,244 | 27,660,947 | 4,272,736 | May 08 05:47 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 08 | Sale | 158.50 | 500,000 | 79,250,000 | 4,230,539 | May 08 05:47 PM | | INCY | BAKER BROS. ADVISORS LP | Director | Apr 28 | Option Exercise | 13.34 | 40,000 | 533,600 | 29,311,915 | Apr 29 04:45 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | Apr 23 | Option Exercise | 12.76 | 35,000 | 446,600 | 45,860,149 | Apr 24 04:25 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Mar 16 | Buy | 31.51 | 694,303 | 21,878,017 | 38,107,749 | Mar 18 06:47 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Mar 17 | Buy | 32.84 | 219,800 | 7,218,907 | 38,309,339 | Mar 18 06:47 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Mar 18 | Buy | 33.52 | 135,897 | 4,555,101 | 38,433,977 | Mar 18 06:47 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Mar 16 | Buy | 39.97 | 104,600 | 4,180,977 | 10,560,911 | Mar 18 06:47 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Mar 17 | Buy | 38.99 | 10,000 | 389,850 | 10,570,083 | Mar 18 06:47 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Mar 18 | Buy | 37.37 | 35,400 | 1,322,977 | 10,602,550 | Mar 18 06:47 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Mar 18 | Buy | 82.01 | 81,379 | 6,673,935 | 7,841,556 | Mar 18 06:46 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Mar 16 | Buy | 78.76 | 265,298 | 20,894,753 | 7,626,298 | Mar 18 06:45 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Mar 17 | Buy | 76.51 | 102,421 | 7,836,585 | 7,720,234 | Mar 18 06:45 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Mar 18 | Buy | 79.76 | 50,902 | 4,059,792 | 7,766,918 | Mar 18 06:45 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Feb 24 | Buy | 57.56 | 71,123 | 4,093,553 | 10,184,170 | Feb 26 05:06 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Feb 25 | Buy | 57.91 | 206,126 | 11,937,248 | 10,373,248 | Feb 26 05:06 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Feb 26 | Buy | 57.99 | 100,000 | 5,799,441 | 10,464,977 | Feb 26 05:06 PM | | NLTX | BAKER BROS. ADVISORS LP | Director | Dec 20 | Buy | 8.40 | 3,017,542 | 25,347,353 | 12,872,664 | Dec 20 05:16 PM | | KOD | BAKER BROS. ADVISORS LP | Director | Dec 06 | Buy | 46.00 | 1,902,173 | 87,499,958 | 10,118,929 | Dec 06 04:46 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Sep 20 | Buy | 40.00 | 1,562,500 | 62,500,000 | 37,470,965 | Sep 20 04:28 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | May 28 | Sale | 126.53 | 123,489 | 15,624,859 | 971,803 | May 30 05:16 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | May 29 | Sale | 122.20 | 119,062 | 14,548,851 | 959,035 | May 30 05:16 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | May 30 | Sale | 120.97 | 57,449 | 6,949,754 | 952,874 | May 30 05:16 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | Apr 29 | Option Exercise | 8.38 | 20,000 | 167,600 | 45,839,686 | May 01 04:59 PM | | INCY | BAKER BROS. ADVISORS LP | Director | Feb 26 | Option Exercise | 2.80 | 40,000 | 112,000 | 29,288,793 | Feb 27 05:19 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Nov 30 | Buy | 17.00 | 11,764,705 | 199,999,985 | 35,976,940 | Dec 04 05:00 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Sep 20 | Buy | 18.70 | 1,210,776 | 22,646,989 | 24,798,117 | Sep 24 08:32 AM | | BGNE | BAKER BROS. ADVISORS LP | Director | Aug 02 | Buy | 108.00 | 5,814,100 | 627,922,800 | 5,250,491 | Aug 06 05:22 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 04 | Buy | 52.68 | 204,537 | 10,775,582 | 45,569,872 | May 08 05:17 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 07 | Buy | 53.70 | 129,715 | 6,966,305 | 45,699,587 | May 08 05:17 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 08 | Buy | 54.02 | 126,399 | 6,828,339 | 45,825,986 | May 08 05:17 PM | | INCY | BAKER BROS. ADVISORS LP | Director | May 02 | Option Exercise | 9.92 | 60,000 | 595,200 | 29,267,937 | May 03 04:19 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 01 | Option Exercise | 10.08 | 20,000 | 201,600 | 44,988,471 | May 02 06:05 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 01 | Buy | 51.36 | 306,917 | 15,764,736 | 45,295,388 | May 02 06:05 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 02 | Buy | 52.57 | 69,947 | 3,676,836 | 45,365,335 | May 02 06:05 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | Apr 30 | Buy | 51.06 | 623,136 | 31,816,925 | 44,978,471 | May 02 06:05 PM | | NVTA | BAKER BROS. ADVISORS LP | 10% Owner | Mar 28 | Buy | 4.50 | 1,111,111 | 5,000,000 | 7,480,182 | Mar 29 03:59 PM | | IDRA | BAKER BROS. ADVISORS LP | Director | Mar 15 | Option Exercise | 0.47 | 20,316,327 | 9,548,674 | 34,193,251 | Mar 15 04:10 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | Feb 01 | Buy | 52.00 | 3,846,153 | 199,999,956 | 44,355,335 | Feb 05 04:00 PM | | BGNE | BAKER BROS. ADVISORS LP | Director | Jan 18 | Buy | 101.00 | 1,980,198 | 199,999,998 | 5,121,404 | Jan 22 05:03 PM | | BLCM | BAKER BROS. ADVISORS LP | 10% Owner | Jan 17 | Sale | 8.63 | 260,600 | 2,247,910 | 66,815 | Jan 19 04:57 PM | | BLCM | BAKER BROS. ADVISORS LP | 10% Owner | Jan 18 | Sale | 8.12 | 324,774 | 2,635,768 | 62,267 | Jan 19 04:57 PM | | BLCM | BAKER BROS. ADVISORS LP | 10% Owner | Jan 19 | Sale | 7.91 | 295,361 | 2,336,217 | 58,131 | Jan 19 04:57 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Nov 27 | Option Exercise | 1.38 | 39,378 | 54,342 | 491,918 | Nov 29 04:00 PM | | IDRA | BAKER BROS. ADVISORS LP | Director | Oct 26 | Buy | 1.50 | 8,000,000 | 12,000,000 | 16,557,473 | Oct 30 05:12 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Oct 13 | Option Exercise | 1.38 | 1,426,590 | 1,968,694 | 23,763,865 | Oct 16 05:15 PM | | INCY | BAKER BROS. ADVISORS LP | Director | Sep 08 | Buy | 132.00 | 100,000 | 13,200,000 | 29,247,347 | Sep 08 05:06 PM | | BGNE | BAKER BROS. ADVISORS LP | Director | Aug 11 | Buy | 71.00 | 176,056 | 12,499,976 | 3,476,256 | Aug 14 03:49 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Jun 14 | Buy | 118.00 | 4,392 | 518,256 | 7,321,850 | Jun 16 04:04 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Jun 15 | Buy | 117.33 | 656,387 | 77,012,491 | 7,645,906 | Jun 16 04:04 PM | | ALXN | BAKER BROS. ADVISORS LP | Director | Jun 14 | Buy | 116.32 | 1,348,955 | 156,915,444 | 7,317,906 | Jun 16 04:03 PM | | SGEN | BAKER BROS. ADVISORS LP | Director | May 15 | Option Exercise | 10.20 | 20,000 | 204,000 | 40,895,092 | May 17 05:26 PM | | INCY | BAKER BROS. ADVISORS LP | Director | Apr 27 | Option Exercise | 7.26 | 60,000 | 435,600 | 29,161,795 | Apr 28 05:10 PM | | BLCM | BAKER BROS. ADVISORS LP | 10% Owner | Mar 24 | Buy | 12.00 | 166,666 | 1,999,992 | 4,527,089 | Mar 28 05:05 PM | | BGNE | BAKER BROS. ADVISORS LP | Director | Nov 18 | Buy | 32.00 | 1,760,495 | 56,335,840 | 3,317,977 | Nov 21 06:13 PM | | NVTA | BAKER BROS. ADVISORS LP | 10% Owner | Nov 17 | Buy | 6.00 | 733,333 | 4,399,998 | 6,480,668 | Nov 18 04:36 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Aug 12 | Sale | 5.02 | 3,645,600 | 18,315,817 | 1,607,944 | Aug 16 06:11 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Aug 15 | Sale | 4.83 | 400,000 | 1,931,040 | 1,551,527 | Aug 16 06:11 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Aug 16 | Sale | 4.29 | 990 | 4,246 | 1,551,387 | Aug 16 06:11 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Aug 10 | Buy | 33.00 | 1,303,030 | 42,999,990 | 22,337,275 | Aug 12 04:08 PM | | MRTX | BAKER BROS. ADVISORS LP | 10% Owner | Jun 07 | Sale | 9.44 | 296,200 | 2,795,476 | 39,586 | Jun 09 05:06 PM | | MRTX | BAKER BROS. ADVISORS LP | 10% Owner | Jun 08 | Sale | 9.21 | 158,100 | 1,456,480 | 37,432 | Jun 09 05:06 PM | | MRTX | BAKER BROS. ADVISORS LP | 10% Owner | Jun 09 | Sale | 9.45 | 545,058 | 5,150,516 | 30,003 | Jun 09 05:06 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Mar 30 | Buy | 25.94 | 462,546 | 12,000,056 | 2,799,646 | Apr 01 04:21 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Mar 31 | Buy | 27.21 | 683,644 | 18,601,180 | 20,894,327 | Apr 01 04:21 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Apr 01 | Buy | 28.52 | 302,900 | 8,638,572 | 21,167,398 | Apr 01 04:21 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Feb 05 | Buy | 6.33 | 45,000 | 284,657 | 12,894,240 | Feb 09 05:24 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Feb 02 | Buy | 6.52 | 91,728 | 598,360 | 12,733,253 | Feb 04 05:15 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Feb 03 | Buy | 6.29 | 91,187 | 573,311 | 12,824,440 | Feb 04 05:15 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Feb 04 | Buy | 6.65 | 24,800 | 164,915 | 12,849,240 | Feb 04 05:15 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Jan 27 | Buy | 6.98 | 63,345 | 441,971 | 12,616,525 | Jan 29 04:42 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Jan 28 | Buy | 6.88 | 25,000 | 172,015 | 12,641,525 | Jan 29 04:42 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Jan 15 | Buy | 7.46 | 200,000 | 1,491,223 | 12,301,485 | Jan 20 07:13 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Jan 19 | Buy | 7.12 | 92,200 | 656,750 | 12,393,685 | Jan 20 07:13 PM | | BCRX | BAKER BROS. ADVISORS LP | 10% Owner | Jan 20 | Buy | 6.87 | 52,695 | 362,171 | 12,446,380 | Jan 20 07:13 PM | | XOMA | BAKER BROS. ADVISORS LP | Former 10% owner | Jul 22 | Sale | 1.09 | 11,000,000 | 12,017,500 | 90,538 | Jul 23 05:35 PM | | MRTX | BAKER BROS. ADVISORS LP | 10% Owner | Jan 29 | Buy | 20.00 | 425,000 | 8,500,000 | 2,604,832 | Feb 02 05:33 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Jan 02 | Sale | 3.55 | 212,100 | 753,740 | 388,063 | Jan 06 08:31 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Jan 05 | Sale | 3.81 | 1,003,300 | 3,824,078 | 366,515 | Jan 06 08:31 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Jan 06 | Sale | 3.86 | 1,000,000 | 3,860,000 | 345,074 | Jan 06 08:31 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 26 | Sale | 3.71 | 131,100 | 486,460 | 405,778 | Dec 30 05:40 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 29 | Sale | 3.68 | 221,000 | 812,440 | 401,032 | Dec 30 05:40 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 30 | Sale | 3.65 | 391,900 | 1,430,239 | 392,617 | Dec 30 05:40 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 17 | Sale | 4.31 | 686,500 | 2,958,129 | 428,343 | Dec 19 05:13 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 18 | Sale | 4.29 | 165,700 | 710,687 | 424,785 | Dec 19 05:13 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 19 | Sale | 4.21 | 752,900 | 3,168,580 | 408,603 | Dec 19 05:13 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 12 | Sale | 4.71 | 253,800 | 1,196,413 | 459,878 | Dec 16 05:29 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 15 | Sale | 4.45 | 460,800 | 2,050,652 | 449,970 | Dec 16 05:29 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 16 | Sale | 4.27 | 319,200 | 1,363,271 | 443,096 | Dec 16 05:29 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 09 | Sale | 4.62 | 392,353 | 1,811,062 | 465,335 | Dec 10 05:50 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 02 | Sale | 5.36 | 500,000 | 2,679,550 | 513,815 | Dec 04 06:05 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 03 | Sale | 4.84 | 567,918 | 2,748,837 | 501,850 | Dec 04 06:05 PM | | XOMA | BAKER BROS. ADVISORS LP | Director | Dec 04 | Sale | 4.55 | 1,304,288 | 5,928,902 | 473,764 | Dec 04 06:05 PM | | ACAD | BAKER BROS. ADVISORS LP | Director | Mar 05 | Buy | 28.50 | 526,316 | 15,000,006 | 18,476,847 | Mar 07 05:27 PM |
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