BENNETT C FRANK - Insider Transactions

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Ticker	Owner	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Sep 05 '25	Sale	59.60	6,000	357,581	82,679	Sep 09 06:30 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Sep 03 '25	Option Exercise	53.77	46,800	2,516,436	135,479	Sep 04 08:29 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Sep 03 '25	Sale	60.62	33,909	2,055,564	101,570	Sep 04 08:29 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Sep 02 '25	Sale	49.14	5,000	245,700	88,679	Sep 04 08:29 PM
IONS	BENNETT C FRANK	Officer	Sep 03 '25	Proposed Sale	60.86	51,800	3,152,698		Sep 03 04:54 PM

IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Aug 18 '25	Option Exercise	32.60	10,000	326,000	103,466	Aug 20 06:14 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Aug 18 '25	Sale	43.98	10,000	439,776	93,466	Aug 20 06:14 PM
IONS	BENNETT C FRANK	Officer	Aug 18 '25	Proposed Sale	43.98	16,000	703,642		Aug 18 04:26 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 31 '25	Sale	32.46	1,327	43,079	93,146	Feb 03 07:26 PM
IONS	BENNETT C FRANK	Officer	Jan 31 '25	Proposed Sale	35.00	1,803	63,105		Jan 31 04:59 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 15 '25	Option Exercise	0.00	18,011	0	97,618	Jan 17 07:40 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 16 '25	Sale	32.90	6,752	222,114	90,866	Jan 17 07:40 PM
IONS	BENNETT C FRANK	Officer	Jan 16 '25	Proposed Sale	32.70	6,752	220,790		Jan 16 07:19 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Feb 02 '24	Sale	49.52	1,853	91,752	79,079	Feb 02 07:54 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 16 '24	Option Exercise	0.00	18,314	0	84,068	Jan 18 05:44 PM

IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 17 '24	Sale	50.42	6,745	340,063	77,323	Jan 18 05:44 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Dec 21 '23	Option Exercise	47.34	16,113	762,789	81,867	Dec 22 07:11 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Dec 20 '23	Option Exercise	47.34	6,500	307,710	72,254	Dec 22 07:11 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Dec 20 '23	Sale	49.64	6,500	322,643	65,754	Dec 22 07:11 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Dec 21 '23	Sale	49.29	16,113	794,211	65,754	Dec 22 07:11 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Dec 14 '23	Option Exercise	47.34	22,612	1,070,452	79,756	Dec 18 04:55 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Dec 14 '23	Sale	49.58	22,612	1,121,195	65,754	Dec 18 04:55 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Sep 28 '23	Sale	46.50	4,460	207,390	65,754	Sep 29 05:20 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Feb 06 '23	Sale	40.57	1,813	73,560	69,651	Feb 07 05:36 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 17 '23	Option Exercise	0.00	19,417	0	74,833	Jan 19 08:19 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 18 '23	Sale	38.89	6,978	271,356	67,855	Jan 19 08:19 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jan 18 '22	Option Exercise	0.00	18,842	0	61,613	Jan 20 08:21 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Jan 15 '21	Option Exercise	0.00	15,520	0	47,996	Jan 20 07:08 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Dec 04 '20	Option Exercise	39.87	7,947	316,847	40,423	Dec 08 08:49 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Dec 04 '20	Sale	51.04	7,947	405,615	32,476	Dec 08 08:49 PM

IONS	BENNETT C FRANK	Chief Scientific Officer	Dec 02 '20	Option Exercise	39.87	7,053	281,203	39,529	Dec 04 08:53 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Dec 02 '20	Sale	51.32	7,053	361,960	32,476	Dec 04 08:53 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Nov 03 '20	Option Exercise	39.87	15,000	598,050	47,476	Nov 05 08:26 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Nov 03 '20	Sale	46.77	15,000	701,600	32,476	Nov 05 08:26 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jun 25 '20	Option Exercise	39.87	15,000	598,050	47,364	Jun 29 09:47 PM
IONS	BENNETT C FRANK	EVP, Chief Scientific Officer	Jun 25 '20	Sale	59.77	15,000	896,505	32,364	Jun 29 09:47 PM
IONS	BENNETT C FRANK	Chief Scientific Officer	Jan 15 '20	Option Exercise	0.00	11,711	0	36,357	Jan 17 06:11 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Feb 01 '19	Option Exercise	14.69	9,013	132,401	33,541	Feb 05 05:59 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Feb 01 '19	Sale	58.29	9,013	525,368	24,528	Feb 05 05:59 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jan 15 '19	Option Exercise	0.00	7,822	0	27,218	Jan 17 07:39 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Nov 01 '18	Option Exercise	14.69	12,500	183,625	31,896	Nov 01 07:34 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Nov 01 '18	Sale	49.54	12,500	619,245	19,396	Nov 01 07:34 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Aug 08 '18	Option Exercise	14.68	12,500	183,528	31,883	Aug 09 06:34 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Aug 08 '18	Sale	45.00	12,500	562,500	19,396	Aug 09 06:34 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	May 11 '18	Option Exercise	7.25	12,500	90,625	31,614	May 11 09:06 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	May 11 '18	Sale	45.00	12,500	562,500	19,114	May 11 09:06 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jan 15 '18	Option Exercise	0.00	6,663	0	21,810	Jan 17 09:22 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jan 16 '18	Sale	51.76	2,696	139,545	19,114	Jan 17 09:22 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Oct 18 '17	Option Exercise	10.29	12,250	126,052	27,291	Oct 20 05:35 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Oct 18 '17	Sale	65.00	12,250	796,250	15,041	Oct 20 05:35 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jul 24 '17	Option Exercise	10.29	10,000	102,900	25,041	Jul 26 08:03 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jul 24 '17	Sale	59.29	10,000	592,900	15,041	Jul 26 08:03 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Mar 03 '17	Option Exercise	10.29	5,000	51,450	19,788	Mar 06 07:25 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Mar 03 '17	Sale	55.00	5,000	275,000	14,788	Mar 06 07:25 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jan 15 '17	Option Exercise	0.00	6,195	0	15,411	Jan 18 06:37 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Jan 17 '17	Sale	46.29	2,421	112,069	11,876	Jan 18 06:37 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Nov 09 '16	Option Exercise	11.27	22,805	257,012	28,608	Nov 14 06:51 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Nov 09 '16	Sale	37.56	22,805	856,605	10,803	Nov 14 06:51 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Nov 07 '16	Option Exercise	11.27	5,000	56,350	15,803	Nov 09 06:22 PM
IONS	BENNETT C FRANK	SVP, Antisense Research	Nov 07 '16	Sale	34.00	5,000	170,000	10,803	Nov 09 06:22 PM

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BENNETT C FRANK - Insider Transactions

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