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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Dec 10 '25 | Proposed Sale | 1.01 | 88,632 | 89,518 | Dec 10 05:02 PM | |
| HOWL | MPM BioVentures 2014, L.P. | Former 10% Owner | Dec 02 '25 | Sale | 0.89 | 59,277 | 52,757 | 4,924,566 | Dec 04 06:19 PM |
| HOWL | MPM BioVentures 2014, L.P. | Former 10% Owner | Dec 03 '25 | Sale | 0.87 | 57,225 | 49,786 | 4,867,341 | Dec 04 06:19 PM |
| HOWL | MPM BioVentures 2014, L.P. | Former 10% Owner | Dec 04 '25 | Sale | 0.97 | 83,230 | 80,733 | 4,784,111 | Dec 04 06:19 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Dec 03 '25 | Proposed Sale | 0.86 | 130,125 | 111,908 | Dec 03 04:38 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 26 '25 | Sale | 0.98 | 60,733 | 59,518 | 5,065,037 | Dec 01 06:12 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 28 '25 | Sale | 0.99 | 20,277 | 20,074 | 5,044,760 | Dec 01 06:12 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Dec 01 '25 | Sale | 0.94 | 60,917 | 57,262 | 4,983,843 | Dec 01 06:12 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 21 '25 | Sale | 0.83 | 64,331 | 53,395 | 5,257,105 | Nov 25 06:04 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 24 '25 | Sale | 0.98 | 88,802 | 87,026 | 5,168,303 | Nov 25 06:04 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 25 '25 | Sale | 0.92 | 42,533 | 39,130 | 5,125,770 | Nov 25 06:04 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 24 '25 | Proposed Sale | 0.87 | 130,125 | 113,625 | Nov 24 04:31 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 18 '25 | Sale | 0.93 | 52,627 | 48,943 | 5,428,912 | Nov 20 05:51 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 19 '25 | Sale | 0.94 | 66,324 | 62,345 | 5,362,588 | Nov 20 05:51 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 20 '25 | Sale | 0.89 | 41,152 | 36,625 | 5,321,436 | Nov 20 05:51 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 13 '25 | Sale | 0.98 | 90,951 | 89,132 | 5,600,240 | Nov 17 07:22 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 14 '25 | Sale | 0.93 | 61,640 | 57,325 | 5,538,600 | Nov 17 07:22 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 17 '25 | Sale | 0.95 | 57,061 | 54,208 | 5,481,539 | Nov 17 07:22 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 17 '25 | Proposed Sale | 0.92 | 130,125 | 119,481 | Nov 17 04:56 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 07 '25 | Sale | 1.11 | 68,480 | 76,013 | 5,836,240 | Nov 12 07:32 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 10 '25 | Sale | 1.18 | 48,570 | 57,313 | 5,787,670 | Nov 12 07:32 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 11 '25 | Sale | 1.14 | 55,810 | 63,623 | 5,731,860 | Nov 12 07:32 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 12 '25 | Sale | 1.09 | 40,669 | 44,329 | 5,691,191 | Nov 12 07:32 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 10 '25 | Proposed Sale | 1.15 | 130,125 | 149,644 | Nov 10 04:53 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 04 '25 | Sale | 1.22 | 140,488 | 171,395 | 6,007,122 | Nov 06 07:41 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 05 '25 | Sale | 1.22 | 47,950 | 58,499 | 5,959,172 | Nov 06 07:41 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 06 '25 | Sale | 1.21 | 54,452 | 65,887 | 5,904,720 | Nov 06 07:41 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 04 '25 | Proposed Sale | 1.31 | 130,125 | 170,464 | Nov 04 04:46 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 30 '25 | Sale | 1.43 | 86,936 | 124,318 | 6,355,717 | Nov 03 07:08 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 31 '25 | Sale | 1.28 | 114,044 | 145,976 | 6,241,673 | Nov 03 07:08 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 03 '25 | Sale | 1.29 | 94,063 | 121,341 | 6,147,610 | Nov 03 07:08 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Oct 30 '25 | Proposed Sale | 1.56 | 130,125 | 202,995 | Oct 30 05:08 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 27 '25 | Sale | 1.72 | 72,709 | 125,059 | 6,645,961 | Oct 29 07:21 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 28 '25 | Sale | 1.64 | 69,068 | 113,272 | 6,576,893 | Oct 29 07:21 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 29 '25 | Sale | 1.55 | 134,240 | 208,072 | 6,442,653 | Oct 29 07:21 PM |
| HOWL | MPM BioVentures 2014, L.P. | Shareholder | Oct 27 '25 | Proposed Sale | 1.77 | 130,125 | 230,321 | Oct 27 04:58 PM | |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | Mar 27 '25 | Sale | 1.05 | 1,963 | 2,061 | 3,208,793 | Apr 30 04:17 PM |
| TRDA | MPM BioVentures 2014, L.P. | 10% Owner | Dec 10 '24 | Sale | 20.77 | 22,935 | 476,360 | 4,402,849 | Dec 12 05:00 PM |
| TRDA | MPM BioVentures 2014, L.P. | 10% Owner | Dec 11 '24 | Sale | 20.23 | 21,787 | 440,751 | 4,381,062 | Dec 12 05:00 PM |
| HOWL | MPM BioVentures 2014, L.P. | 10% Owner | May 04 '21 | Buy | 16.00 | 125,759 | 2,012,144 | 3,187,998 | May 06 04:20 PM |
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