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| Ticker | Owner | Relationship | Date | Transaction | Cost |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| AGIO | Gheuens Sarah | Chief Medical Officer | Nov 11 '25 | Option Exercise | 25.01 | 2,454 | 61,375 | 64,181 | Nov 13 04:08 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Nov 11 '25 | Sale | 43.78 | 2,454 | 107,436 | 61,727 | Nov 13 04:08 PM |
| AGIO | SARAH GHEUENS | Officer | Nov 11 '25 | Proposed Sale | 43.78 | 2,454 | 107,441 | Nov 12 10:35 AM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Oct 30 '25 | Option Exercise | 25.01 | 200 | 5,002 | 61,927 | Nov 03 04:10 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Oct 30 '25 | Sale | 43.81 | 200 | 8,762 | 61,727 | Nov 03 04:10 PM |
| AGIO | SARAH GHEUENS | Officer | Oct 30 '25 | Proposed Sale | 43.81 | 200 | 8,762 | Oct 30 05:02 PM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Oct 27 '25 | Option Exercise | 25.01 | 3,302 | 82,583 | 65,029 | Oct 29 04:02 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Oct 27 '25 | Sale | 43.92 | 3,302 | 145,024 | 61,727 | Oct 29 04:02 PM |
| AGIO | SARAH GHEUENS | Officer | Oct 27 '25 | Proposed Sale | 43.92 | 3,302 | 145,028 | Oct 27 04:32 PM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jul 09 '25 | Option Exercise | 25.01 | 11,914 | 297,969 | 73,185 | Jul 11 04:59 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jul 09 '25 | Sale | 37.99 | 11,914 | 452,601 | 61,271 | Jul 11 04:59 PM |
| AGIO | SARAH GHEUENS | Officer | Jul 09 '25 | Proposed Sale | 37.99 | 11,914 | 452,632 | Jul 09 04:59 PM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jul 01 '25 | Option Exercise | 0.00 | 8,374 | 0 | 65,362 | Jul 03 04:01 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jul 01 '25 | Sale | 34.17 | 4,091 | 139,789 | 61,271 | Jul 03 04:01 PM |
| AGIO | Gheuens Sarah | Officer | Jul 01 '25 | Proposed Sale | 34.37 | 4,091 | 140,608 | Jul 01 04:03 PM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jun 24 '25 | Option Exercise | 0.00 | 6,000 | 0 | 59,897 | Jun 26 05:25 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jun 24 '25 | Sale | 33.54 | 2,909 | 97,568 | 56,988 | Jun 26 05:25 PM |
| AGIO | Gheuens Sarah | Officer | Jun 24 '25 | Proposed Sale | 34.41 | 1,761 | 60,596 | Jun 24 04:05 PM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Mar 01 '25 | Option Exercise | 0.00 | 13,500 | 0 | 55,578 | Mar 04 04:08 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Mar 03 '25 | Sale | 35.54 | 4,005 | 142,338 | 47,098 | Mar 04 04:08 PM |
| AGIO | Gheuens Sarah | Officer | Mar 03 '25 | Proposed Sale | 35.54 | 4,005 | 142,338 | Mar 03 04:44 PM | |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jul 01 '24 | Option Exercise | 0.00 | 8,375 | 0 | 47,441 | Jul 03 04:30 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jul 01 '24 | Sale | 43.85 | 3,705 | 162,464 | 43,736 | Jul 03 04:30 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Mar 01 '24 | Option Exercise | 0.00 | 7,834 | 0 | 40,415 | Mar 05 04:20 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Mar 05 '24 | Sale | 32.57 | 2,642 | 86,050 | 36,415 | Mar 05 04:20 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Feb 12 '24 | Option Exercise | 0.00 | 2,162 | 0 | 34,073 | Feb 14 05:53 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Feb 14 '24 | Sale | 25.14 | 642 | 16,140 | 33,431 | Feb 14 05:53 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jan 20 '24 | Option Exercise | 0.00 | 5,750 | 0 | 33,619 | Jan 24 04:24 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jan 24 '24 | Sale | 21.64 | 1,708 | 36,961 | 31,911 | Jan 24 04:24 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jan 05 '24 | Option Exercise | 0.00 | 5,000 | 0 | 29,658 | Jan 09 04:22 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jan 09 '24 | Sale | 22.99 | 1,789 | 41,129 | 27,869 | Jan 09 04:22 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jun 28 '23 | Option Exercise | 0.00 | 5,750 | 0 | 25,866 | Jun 30 04:06 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Jun 30 '23 | Sale | 28.36 | 1,707 | 48,411 | 24,159 | Jun 30 04:06 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Mar 01 '23 | Option Exercise | 0.00 | 3,833 | 0 | 21,250 | Mar 03 04:05 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Dec 23 '22 | Option Exercise | 0.00 | 9,375 | 0 | 18,388 | Dec 28 04:05 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Dec 02 '22 | Option Exercise | 0.00 | 833 | 0 | 9,261 | Dec 06 04:14 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Feb 18 '22 | Option Exercise | 0.00 | 3,271 | 0 | 8,723 | Feb 23 04:12 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Feb 10 '22 | Option Exercise | 0.00 | 2,162 | 0 | 6,210 | Feb 14 04:09 PM |
| AGIO | Gheuens Sarah | Chief Medical Officer | Dec 02 '21 | Option Exercise | 0.00 | 834 | 0 | 4,296 | Dec 07 04:18 PM |
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