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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| MBX | Hoerter Steven L. | Director | Oct 17 '25 | Buy | 13.25 | 20,000 | 264,984 | 20,000 | Oct 20 04:44 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Mar 01 '19 | Option Exercise | 39.76 | 5,000 | 198,800 | 15,941 | Mar 05 04:04 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Mar 04 '19 | Option Exercise | 39.76 | 5,000 | 198,800 | 15,941 | Mar 05 04:04 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Mar 04 '19 | Sale | 68.00 | 5,000 | 340,000 | 10,941 | Mar 05 04:04 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Mar 01 '19 | Sale | 66.01 | 5,000 | 330,050 | 10,941 | Mar 05 04:04 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Aug 24 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | Aug 28 04:06 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Aug 24 '18 | Sale | 74.92 | 2,050 | 153,586 | 0 | Aug 28 04:06 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Jul 25 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | Jul 27 04:01 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Jul 25 '18 | Sale | 84.58 | 2,050 | 173,389 | 0 | Jul 27 04:01 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Jun 22 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | Jun 26 04:02 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Jun 22 '18 | Sale | 97.58 | 2,050 | 200,039 | 0 | Jun 26 04:02 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | May 23 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | May 29 06:14 AM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | May 23 '18 | Sale | 85.76 | 2,050 | 175,808 | 0 | May 29 06:14 AM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Apr 23 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | Apr 25 04:12 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Apr 23 '18 | Sale | 85.95 | 2,050 | 176,198 | 0 | Apr 25 04:12 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Mar 22 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | Mar 26 04:01 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Mar 22 '18 | Sale | 84.65 | 2,050 | 173,532 | 0 | Mar 26 04:01 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Feb 22 '18 | Option Exercise | 39.76 | 2,050 | 81,508 | 2,050 | Feb 26 04:45 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Feb 22 '18 | Sale | 78.63 | 2,050 | 161,192 | 0 | Feb 26 04:45 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Jan 23 '18 | Option Exercise | 39.76 | 25,000 | 994,000 | 25,000 | Jan 25 04:03 PM |
| AGIO | Hoerter Steven L. | Chief Commercial Officer | Jan 23 '18 | Sale | 74.83 | 25,000 | 1,870,750 | 0 | Jan 25 04:03 PM |
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