 TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Sep 04 '26 | Sale | 7.11 | 38,500 | 273,735 | 4,106,452 | Sep 09 07:23 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Sep 08 '26 | Sale | 7.41 | 192,500 | 1,426,425 | 3,913,952 | Sep 09 07:23 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Sep 09 '26 | Sale | 7.13 | 28,837 | 205,608 | 3,885,115 | Sep 09 07:23 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Sep 01 '26 | Sale | 7.06 | 29,088 | 205,361 | 4,202,346 | Sep 03 07:21 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Sep 02 '26 | Sale | 7.19 | 25,131 | 180,692 | 4,177,215 | Sep 03 07:21 PM |
|
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Sep 03 '26 | Sale | 7.17 | 32,263 | 231,326 | 4,144,952 | Sep 03 07:21 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Aug 27 '26 | Sale | 7.20 | 38,922 | 280,238 | 4,279,426 | Aug 31 06:25 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Aug 28 '26 | Sale | 7.01 | 3,733 | 26,168 | 4,275,693 | Aug 31 06:25 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Aug 31 '26 | Sale | 6.99 | 44,259 | 309,370 | 4,231,434 | Aug 31 06:25 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Aug 24 '26 | Sale | 7.34 | 21,623 | 158,713 | 4,359,439 | Aug 26 09:28 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Aug 25 '26 | Sale | 7.54 | 26,522 | 199,976 | 4,332,917 | Aug 26 09:28 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Aug 26 '26 | Sale | 7.06 | 14,569 | 102,857 | 4,318,348 | Aug 26 09:28 PM |
 HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Jul 06 '26 | Proposed Sale | 0.34 | 96,873 | 32,976 | | Jul 06 05:18 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Jun 29 '26 | Proposed Sale | 0.32 | 106,262 | 34,323 | | Jun 29 05:29 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | May 28 '26 | Proposed Sale | 0.49 | 244,185 | 119,651 | | May 28 05:04 PM |
|
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | May 18 '26 | Proposed Sale | 0.52 | 290,419 | 149,595 | | May 18 05:02 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | May 11 '26 | Proposed Sale | 0.68 | 84,491 | 57,454 | | May 11 04:32 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | May 01 '26 | Proposed Sale | 0.72 | 363,593 | 261,642 | | May 01 04:51 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Apr 29 '26 | Proposed Sale | 0.74 | 130,115 | 96,285 | | Apr 29 04:47 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Apr 27 '26 | Proposed Sale | 0.81 | 130,115 | 105,784 | | Apr 27 05:00 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Jan 06 '26 | Proposed Sale | 0.64 | 198,739 | 128,067 | | Jan 06 04:54 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Dec 29 '25 | Proposed Sale | 0.65 | 130,125 | 85,141 | | Dec 29 04:46 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Dec 22 '25 | Proposed Sale | 0.69 | 130,125 | 89,370 | | Dec 22 04:57 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Dec 10 '25 | Proposed Sale | 1.01 | 88,632 | 89,518 | | Dec 10 05:02 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Former 10% Owner | Dec 02 '25 | Sale | 0.89 | 59,277 | 52,757 | 4,924,566 | Dec 04 06:19 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Former 10% Owner | Dec 03 '25 | Sale | 0.87 | 57,225 | 49,786 | 4,867,341 | Dec 04 06:19 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Former 10% Owner | Dec 04 '25 | Sale | 0.97 | 83,230 | 80,733 | 4,784,111 | Dec 04 06:19 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Dec 03 '25 | Proposed Sale | 0.86 | 130,125 | 111,908 | | Dec 03 04:38 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 26 '25 | Sale | 0.98 | 60,733 | 59,518 | 5,065,037 | Dec 01 06:12 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 28 '25 | Sale | 0.99 | 20,277 | 20,074 | 5,044,760 | Dec 01 06:12 PM |
|
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Dec 01 '25 | Sale | 0.94 | 60,917 | 57,262 | 4,983,843 | Dec 01 06:12 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 21 '25 | Sale | 0.83 | 64,331 | 53,395 | 5,257,105 | Nov 25 06:04 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 24 '25 | Sale | 0.98 | 88,802 | 87,026 | 5,168,303 | Nov 25 06:04 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 25 '25 | Sale | 0.92 | 42,533 | 39,130 | 5,125,770 | Nov 25 06:04 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 24 '25 | Proposed Sale | 0.87 | 130,125 | 113,625 | | Nov 24 04:31 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 18 '25 | Sale | 0.93 | 52,627 | 48,943 | 5,428,912 | Nov 20 05:51 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 19 '25 | Sale | 0.94 | 66,324 | 62,345 | 5,362,588 | Nov 20 05:51 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 20 '25 | Sale | 0.89 | 41,152 | 36,625 | 5,321,436 | Nov 20 05:51 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 13 '25 | Sale | 0.98 | 90,951 | 89,132 | 5,600,240 | Nov 17 07:22 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 14 '25 | Sale | 0.93 | 61,640 | 57,325 | 5,538,600 | Nov 17 07:22 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 17 '25 | Sale | 0.95 | 57,061 | 54,208 | 5,481,539 | Nov 17 07:22 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 17 '25 | Proposed Sale | 0.92 | 130,125 | 119,481 | | Nov 17 04:56 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 07 '25 | Sale | 1.11 | 68,480 | 76,013 | 5,836,240 | Nov 12 07:32 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 10 '25 | Sale | 1.18 | 48,570 | 57,313 | 5,787,670 | Nov 12 07:32 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 11 '25 | Sale | 1.14 | 55,810 | 63,623 | 5,731,860 | Nov 12 07:32 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 12 '25 | Sale | 1.09 | 40,669 | 44,329 | 5,691,191 | Nov 12 07:32 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 10 '25 | Proposed Sale | 1.15 | 130,125 | 149,644 | | Nov 10 04:53 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 04 '25 | Sale | 1.22 | 140,488 | 171,395 | 6,007,122 | Nov 06 07:41 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 05 '25 | Sale | 1.22 | 47,950 | 58,499 | 5,959,172 | Nov 06 07:41 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 06 '25 | Sale | 1.21 | 54,452 | 65,887 | 5,904,720 | Nov 06 07:41 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Nov 04 '25 | Proposed Sale | 1.31 | 130,125 | 170,464 | | Nov 04 04:46 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 30 '25 | Sale | 1.43 | 86,936 | 124,318 | 6,355,717 | Nov 03 07:08 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 31 '25 | Sale | 1.28 | 114,044 | 145,976 | 6,241,673 | Nov 03 07:08 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Nov 03 '25 | Sale | 1.29 | 94,063 | 121,341 | 6,147,610 | Nov 03 07:08 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Oct 30 '25 | Proposed Sale | 1.56 | 130,125 | 202,995 | | Oct 30 05:08 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 27 '25 | Sale | 1.72 | 72,709 | 125,059 | 6,645,961 | Oct 29 07:21 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 28 '25 | Sale | 1.64 | 69,068 | 113,272 | 6,576,893 | Oct 29 07:21 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Oct 29 '25 | Sale | 1.55 | 134,240 | 208,072 | 6,442,653 | Oct 29 07:21 PM |
| HHOWL | MPM BioVentures 2014, L.P. | Shareholder | Oct 27 '25 | Proposed Sale | 1.77 | 130,125 | 230,321 | | Oct 27 04:58 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | Mar 27 '25 | Sale | 1.05 | 1,963 | 2,061 | 3,208,793 | Apr 30 04:17 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Dec 10 '24 | Sale | 20.77 | 22,935 | 476,360 | 4,402,849 | Dec 12 05:00 PM |
| TTRDA | MPM BioVentures 2014, L.P. | 10% Owner | Dec 11 '24 | Sale | 20.23 | 21,787 | 440,751 | 4,381,062 | Dec 12 05:00 PM |
| HHOWL | MPM BioVentures 2014, L.P. | 10% Owner | May 04 '21 | Buy | 16.00 | 125,759 | 2,012,144 | 3,187,998 | May 06 04:20 PM |
