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Citizens JMP Keeps Market Outperform Rating on Rhythm Pharmaceuticals (RYTM)

By Ali Ahmed | September 01, 2025, 1:04 AM

Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) is one of the 10 Hot Mid Cap Stocks to Buy Now. On August 21, Citizens JMP reaffirmed a Market Outperform rating on Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) with a price target of $135.

This decision came after Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) reported that the FDA has accepted for filing the company’s supplemental New Drug Application (sNDA) for review with Priority status for setmelanotide for hypothalamic obesity.

Citizens JMP Keeps Market Outperform Rating on Rhythm Pharmaceuticals (RYTM)

The firm sees a big market opportunity for setmelanotide in hypothalamic obesity. Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) estimates between 5,000 and 10,000 patients in the US, which represents a potential market worth $2 to $4 billion. There is a similar number of patients in Europe, but the market size may be smaller because of pricing adjustments.

Citizens JMP estimates Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) could see peak sales for setmelanotide reach $1.5 billion in the US, $340 million in Europe, and $180 million in Japan. The company expects Phase 3 data from Japan in the first quarter of 2026.

Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM) is a commercial-stage biopharmaceutical company focused on developing and commercializing precision medicines for rare neuroendocrine diseases.

While we acknowledge the potential of RYTM as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you’re looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock.

READ NEXT: 11 Best Revenue Growth Stocks to Buy Now and 11 Best Under-the-Radar Stocks to Buy Right Now.

Disclosure: None. This article is originally published at Insider Monkey.

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