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Morgan Stanley Maintains Overweight Rating For Exelixis, Inc. (EXEL), Price Target Raised To $50

By Ashar Jawad | September 26, 2025, 10:47 AM

Exelixis, Inc. (NASDAQ:EXEL) is among the Renaissance Technologies Portfolio: 10 Biggest Stocks. On September 17, Morgan Stanley raised the stock’s price target to $50 from $46, while maintaining an Overweight rating for its shares.

Morgan Stanley Maintains Overweight Rating For Exelixis, Inc. (EXEL), Price Target Raised To $50
Stock market data showing an upward trajectory. Photo by Burak The Weekender on Pexels

In a research note to investors, the analyst noted that Zanzalintinib presents a significant opportunity for the company, with near-term catalysts that could drive further share price upside. The firm mentioned that it was now modelling approximately $4.7 billion in peak unadjusted Zanzalintinib sales across renal cell carcinoma, colorectal, and neuroendocrine tumors.

In other related news, both Goldman Sachs and Barclays recently initiated coverage of Exelixis, Inc. (NASDAQ:EXEL), with Buy and Equal-Weight ratings, respectively, and announced price targets of $47 and $40, respectively.

Overall, Wall Street analysts have a bullish outlook for the stock, with a consensus Buy rating and an average share price upside potential of 11%.

Exelixis, Inc. (NASDAQ:EXEL) is an oncology company focused on the discovery, development, and commercialization of medicines to treat cancer.

While we acknowledge the potential of EXEL as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you're looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock.

READ NEXT: 12 Best Defense Stocks to Buy Right Now and 15 Stocks ChatGPT Predicts Could Make You Wealthy in 5 Years.

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