New: Introducing “Why Is It Moving?” - lightning-fast, AI-driven explanations of stock moves

Learn More

AMD, Oracle Expand Partnership to Deploy Next-Gen AI Supercluster with MI450 GPUs

By Maham Fatima | October 21, 2025, 5:37 AM

Advanced Micro Devices Inc. (NASDAQ:AMD) is one of the best big tech stocks to invest in now. On October 14, Advanced Micro Devices, or simply, AMD, and Oracle Corporation (NYSE:ORCL) announced a significant expansion of their multi-generation partnership to help customers achieve next-generation AI scale. This builds on years of co-innovation, which included the launch of AMD Instinct MI300X powered shapes on Oracle Cloud Infrastructure/OCI in 2024.

The key announcement is that Oracle will be the first hyperscaler to offer a publicly available AI supercluster powered by the next-generation AMD Instinct MI450 Series GPUs. The deployment of this AI supercluster will begin in calendar Q3 2026 with an initial installment of 50,000 AMD Instinct MI450 Series GPUs, with plans for further expansion in 2027 and beyond.

AMD, Oracle Expand Partnership to Deploy Next-Gen AI Supercluster with MI450 GPUs

The new OCI AI superclusters will be powered by the AMD “Helios” rack design, which includes the AMD Instinct MI450 Series GPUs, next-generation AMD EPYC CPUs codenamed “Venice,” and next-generation AMD Pensando advanced networking codenamed “Vulcano.” This vertically-optimized, rack-scale architecture is designed for maximum performance, scalability, and energy efficiency for large-scale AI training and inference.

Advanced Micro Devices Inc. (NASDAQ:AMD) is a semiconductor company that operates in three segments: Data Center, Client & Gaming, and Embedded.

Oracle Corporation (NYSE:ORCL) offers products and services that address enterprise information technology environments worldwide.

While we acknowledge the potential of AMD as an investment, we believe certain AI stocks offer greater upside potential and carry less downside risk. If you’re looking for an extremely undervalued AI stock that also stands to benefit significantly from Trump-era tariffs and the onshoring trend, see our free report on the best short-term AI stock.

READ NEXT: 30 Stocks That Should Double in 3 Years and 11 Hidden AI Stocks to Buy Right Now.

Disclosure: None. This article is originally published at Insider Monkey.

Latest News

58 min
1 hour
1 hour
1 hour
1 hour
2 hours
4 hours
4 hours
4 hours
4 hours
5 hours
5 hours
5 hours
6 hours
Oct-20