Myriad Genetics (MYGN): Buy, Sell, or Hold Post Q3 Earnings?

By Petr Huřťák | December 08, 2025, 11:03 PM

MYGN Cover Image

Myriad Genetics’s 38.9% return over the past six months has outpaced the S&P 500 by 24.6%, and its stock price has climbed to $7.21 per share. This was partly due to its solid quarterly results, and the run-up might have investors contemplating their next move.

Is there a buying opportunity in Myriad Genetics, or does it present a risk to your portfolio? Dive into our full research report to see our analyst team’s opinion, it’s free for active Edge members.

Why Do We Think Myriad Genetics Will Underperform?

We’re glad investors have benefited from the price increase, but we're cautious about Myriad Genetics. Here are three reasons why MYGN doesn't excite us and a stock we'd rather own.

1. Long-Term Revenue Growth Disappoints

A company’s long-term sales performance can indicate its overall quality. Any business can experience short-term success, but top-performing ones enjoy sustained growth for years. Unfortunately, Myriad Genetics’s 6.7% annualized revenue growth over the last five years was mediocre. This fell short of our benchmark for the healthcare sector.

Myriad Genetics Quarterly Revenue

2. Previous Growth Initiatives Have Lost Money

Growth gives us insight into a company’s long-term potential, but how capital-efficient was that growth? Enter ROIC, a metric showing how much operating profit a company generates relative to the money it has raised (debt and equity).

Myriad Genetics’s five-year average ROIC was negative 33.2%, meaning management lost money while trying to expand the business. Its returns were among the worst in the healthcare sector.

Myriad Genetics Trailing 12-Month Return On Invested Capital

3. New Investments Fail to Bear Fruit as ROIC Declines

A company’s ROIC, or return on invested capital, shows how much operating profit it makes compared to the money it has raised (debt and equity).

We like to invest in businesses with high returns, but the trend in a company’s ROIC is what often surprises the market and moves the stock price. Over the last few years, Myriad Genetics’s ROIC has unfortunately decreased significantly. Paired with its already low returns, these declines suggest its profitable growth opportunities are few and far between.

Myriad Genetics Trailing 12-Month Return On Invested Capital

Final Judgment

Myriad Genetics falls short of our quality standards. With its shares beating the market recently, the stock trades at 226.3× forward P/E (or $7.21 per share). This multiple tells us a lot of good news is priced in - we think there are better opportunities elsewhere. We’d recommend looking at a fast-growing restaurant franchise with an A+ ranch dressing sauce.

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