Is Sarepta Therapeutics, Inc. (SRPT) the Most Promising Long-Term Stock According to Analysts?

By Maham Fatima | April 21, 2025, 10:19 PM

We recently published a list of the 11 Most Promising Long-Term Stocks According to Analysts. In this article, we are going to take a look at where Sarepta Therapeutics, Inc. (NASDAQ:SRPT) stands against other promising long-term stocks.

On March 31, Banrion’s Shana Sissel recently appeared on CNBC’s ‘Power Lunch’ to discuss that buying at lower valuations is favorable for long-term investors. Shana Sissel highlighted that the markets now want transparency, given the persistent volatility that has lasted for a while now. When this clarity is lacking, it becomes difficult for investors and businesses to plan for the long term. This uncertainty has led to soft consumer and CEO confidence, which makes it challenging to develop long-term strategies when key aspects such as industrial policy, business policy, and taxes remain unresolved in the US. Sissel emphasized that until there is more certainty, volatility is likely to persist. She expressed skepticism that any immediate announcements would provide the level of information investors desire, especially because of the administration’s habit of making statements that are later contradicted or revised. However, Sissel pointed out that long-term investors can find attractive buying opportunities if they look beyond the current uncertainty. She noted that the recent drop in valuations for many tech stocks now presents favorable buying opportunities for long-term investors.

Regardless of the short-term fluctuations in policy uncertainty, many tech and security companies still benefit from long-term demand due to trends like the ongoing adoption of AI and the growing need for cybersecurity and infrastructure protection. Even when government decisions are unclear, these sectors are resilient because their products and services address fundamental needs that are unlikely to change with fluctuating market cycles.

Our Methodology

We first sifted through the Finviz stock screener and financial media reports to compile a list of the top stocks with high upside potential of over 40%. We then selected 11 stocks with a 10-year revenue compound annual growth rate of over 20%. The stocks are ranked in ascending order of their upside potential. We have also added the hedge fund sentiment for each stock, as of Q4 2024, which was sourced from Insider Monkey’s database.

Note: All data was sourced on April 21.

Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 373.4% since May 2014, beating its benchmark by 218 percentage points (see more details here).

Is Sarepta Therapeutics Inc. (NASDAQ:SRPT) the Most Promising Long-Term Stock According to Analysts?
A laboratory technician in a white coat holding a microscope and examining a vial of biopharmaceuticals.

Sarepta Therapeutics, Inc. (NASDAQ:SRPT)

10-Year Revenue CAGR: 69.43%

Number of Hedge Fund Holders: 50

Average Upside Potential as of April 21: 230.92%

Sarepta Therapeutics, Inc. (NASDAQ:SRPT) is a commercial-stage biopharmaceutical company that discovers and develops RNA-targeted therapeutics, gene therapies, and other genetic therapeutic modalities for the treatment of rare diseases. It has collaboration and license agreements with several companies and institutions.

ELEVIDYS is Sarepta’s gene therapy for Duchenne Muscular Dystrophy. In Q4 2024 alone, ELEVIDYS sales reached $384.2 million, which was a sequential improvement of 112%. The company projects ELEVIDYS to improve by over 160% year-over-year in 2025 and make up ~two-thirds of Sarepta’s total net product revenue guidance. Since its approval in 2023, ELEVIDYS has made over $1 billion in sales. This figure is still less than 5% of the on-label addressable patient opportunity.

The recent positive two-year and one-year crossover results from the EMBARK trial further solidify the therapy’s transformative potential. With 600+ patients now on therapy across a range of ages and weights, Sarepta Therapeutics, Inc. (NASDAQ:SRPT) is expanding its global reach and improving manufacturing efficiency.

Overall, SRPT ranks 1st on our list of the 11 most promising long-term stocks according to analysts. While we acknowledge the potential of SRPT as an investment, our conviction lies in the belief that AI stocks hold great promise for delivering high returns and doing so within a shorter time frame. There is an AI stock that went up since the beginning of 2025, while popular AI stocks lost around 25%. If you are looking for an AI stock that is more promising than SRPT but that trades at less than 5 times its earnings, check out our report about the cheapest AI stock.

 

READ NEXT: 20 Best AI Stocks To Buy Now and 30 Best Stocks to Buy Now According to Billionaires.

 

Disclosure: None. This article is originally published at Insider Monkey.

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