Evercore ISI Cuts AbbVie Inc. (ABBV) PT, Says Consensus for 2026 and 2027 Still Looks Beatable

AbbVie Inc. (NYSE:ABBV) is included among the 13 Best Roth IRA Stocks to Buy Now.

On February 5, Evercore ISI analyst Gavin Clark-Gartner trimmed his price recommendation on AbbVie Inc. (NYSE:ABBV) to $228 from $232. The analyst maintained an Outperform rating on the stock. In a note to investors, he said that despite Tremfya continuing to gain share, guidance and consensus expectations for 2026 still appear beatable, and the same applies to 2027. He also wrote that it is 2worth noting" that buy-side expectations have been running above consensus for some time, and that margin outperformance now appears more limited. In Evercore’s view, the stock’s pressure is more closely tied to questions around growth beyond 2028, particularly as additional competitors enter the market.

On February 4, AbbVie projected 2026 profit above Wall Street estimates after reporting fourth-quarter results that exceeded expectations. The earnings beat was driven largely by stronger-than-anticipated sales of its older immunology drug, Humira. Even so, the stock declined in morning trading that day as investors reacted to a revenue shortfall from Rinvoq, one of the company’s newer immunology treatments, raising concerns about the durability of its future growth drivers. AbbVie has been counting on Skyrizi and Rinvoq to offset the continued decline in Humira sales, which have been under pressure from lower-cost biosimilars. Humira had once been the world’s top-selling drug, reaching peak global sales of more than $21 billion in 2022 before losing U.S. patent protection.

In the fourth quarter, Skyrizi generated $5.01 billion in sales, ahead of the $4.82 billion analysts had expected. Rinvoq posted $2.37 billion, slightly below the $2.41 billion consensus estimate, according to LSEG data.AbbVie reported adjusted earnings of $2.71 per share for the quarter, exceeding the average analyst estimate of $2.65. The earnings outperformance was supported by Humira, which saw sales decline 25.9% year over year to $1.25 billion but still came in above expectations of $983.8 million. The drug is off patent and anticipated to continue declining.

Looking ahead, AbbVie expects Rinvoq and Skyrizi to generate approximately $31.6 billion combined in 2026, reaching its target of more than $31 billion in annual combined sales a year earlier than planned.

AbbVie Inc. (NYSE:ABBV) is a global research-based biopharmaceutical company engaged in the development, manufacturing, and commercialization of medicines. Its portfolio spans immunology, oncology, aesthetics, neuroscience, eye care, and other key therapeutic areas.

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