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PYPD

Polypid Ltd

Feb 12 • 10:46AM ET

4.50

-0.12 -2.60 %

Healthcare • Biotechnology • Israel • NASD

Feb 11, 4:37 PMPolyPid reports Q4 and full-year 2025 results as it advances D-PLEX100 toward an NDA with FDA support, including positive pre-NDA feedback enabling a rolling submission expected to begin by the end of Q1 2026, with U.S. commercial partnership talks in advanced stages.

Peers: XTLB MRNS ANIP ATHE EPIX AVDL BCTX AUTL IMUX

Scroll to Statements

Index	-	P/E	-	EPS (ttm)	-2.26	Insider Own	45.03%	Shs Outstand	18.20M	Perf Week	3.45%
Market Cap	71.54M	Forward P/E	-	EPS next Y	-0.93	Insider Trans	0.00%	Shs Float	8.74M	Perf Month	2.04%
Enterprise Value	67.75M	PEG	-	EPS next Q	-0.35	Inst Own	22.54%	Short Float	0.32%	Perf Quarter	19.68%
Income	-34.17M	P/S	-	EPS this Y	36.72%	Inst Trans	0.57%	Short Ratio	0.36	Perf Half Y	28.94%
Sales	0.00M	P/B	7.47	EPS next Y	30.06%	ROA	-143.79%	Short Interest	0.03M	Perf YTD	3.69%
Book/sh	0.60	P/C	10.86	EPS next 5Y	-	ROE	-366.29%	52W High	5.12 -12.11%	Perf Year	51.52%
Cash/sh	0.41	P/FCF	-	EPS past 3/5Y	-0.87% 14.14%	ROIC	-294.05%	52W Low	2.30 95.65%	Perf 3Y	-80.25%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	- -	Gross Margin	-	Volatility	6.60% 7.16%	Perf 5Y	-99.01%
Dividend TTM	-	EV/Sales	-	EPS Y/Y TTM	61.23%	Oper. Margin	-	ATR (14)	0.29	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	1.82	Sales Y/Y TTM	-	Profit Margin	-	RSI (14)	49.35	Recom	1.00
Dividend Gr. 3/5Y	- -	Current Ratio	1.97	EPS Q/Q	63.58%	SMA20	-2.21%	Beta	1.49	Target Price	12.25
Payout	-	Debt/Eq	0.26	Sales Q/Q	-	SMA50	3.57%	Rel Volume	0.41	Prev Close	4.62
Employees	61	LT Debt/Eq	0.06	Earnings	Feb 11 BMO	SMA200	24.26%	Avg Volume	76.98K	Price	4.50
IPO	Jun 26, 2020	Option/Short	Yes / Yes	EPS/Sales Surpr.	-24.24% -	Trades		Volume	7,547	Change	-2.60%

Date	Action	Analyst	Rating Change	Price Target Change
Jun-05-25	Initiated	Roth Capital	Buy	$9
Jun-02-25	Resumed	H.C. Wainwright	Buy	$11
Jan-28-25	Initiated	Rodman & Renshaw	Buy	$13
Sep-14-21	Initiated	JMP Securities	Mkt Outperform	$14
Jul-30-21	Initiated	Cantor Fitzgerald	Overweight	$24
Nov-24-20	Upgrade	Raymond James	Outperform → Strong Buy
Aug-10-20	Initiated	Alliance Global Partners	Buy	$27
Jul-21-20	Initiated	Raymond James	Outperform	$23
Jul-21-20	Initiated	BMO Capital Markets	Outperform	$30
Jul-21-20	Initiated	Barclays	Overweight	$22

Feb-11-26 04:03PM	PolyPid Ltd (PYPD) Q4 2025 Earnings Call Highlights: Strategic Advances and Financial Challenges (GuruFocus.com)
09:52AM	PolyPid Q4 Earnings Call Highlights (MarketBeat)
07:30AM	PolyPid Provides Corporate Update and Reports Fourth Quarter and Full-Year 2025 Financial Results (GlobeNewswire)
Jan-28-26 08:00AM	PolyPid to Report Fourth Quarter 2025 Financial Results and Operational Highlights on February 11, 2026 (GlobeNewswire)
Dec-16-25 08:30AM	PolyPid Appoints Veteran MedTech Leader Brooke Story as Chairman of the Board of Directors (GlobeNewswire)
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Dec-03-25 08:30AM	PolyPid Announces Positive FDA Pre-NDA Meeting Minutes for D-PLEX100 Supporting NDA Submission (GlobeNewswire)
Nov-25-25 08:30AM	PolyPid to Participate in ROTH Capital Partners Virtual KOL Event on December 10, 2025 (GlobeNewswire)
Nov-12-25 04:01PM	PolyPid Ltd (PYPD) Q3 2025 Earnings Call Highlights: Strategic Advances and Financial Challenges (GuruFocus.com)
07:30AM	PolyPid Provides Corporate Update and Reports Third Quarter 2025 Financial Results (GlobeNewswire)
Nov-06-25 08:30AM	PolyPid's D-PLEX100 Wins BioTech Breakthrough Award for "Therapeutics Solution of the Year" (GlobeNewswire)
Oct-29-25 08:30AM	PolyPid to Report Third Quarter 2025 Financial Results and Operational Highlights on November 12, 2025 (GlobeNewswire)
Sep-30-25 08:45AM	PolyPid to Present Its Positive Phase 3 SHIELD II Topline Results at the 2025 American College of Surgeons Clinical Congress (GlobeNewswire)
Sep-17-25 08:44AM	PolyPid to Present at Lytham Partners Fall 2025 Investor Conference and Participate in 4th Annual ROTH Healthcare Opportunities Conference (GlobeNewswire)
Sep-16-25 08:30AM	PolyPid Successfully Completes Israeli Ministry of Health GMP Inspection, Advancing Towards Commercial Manufacturing Readiness for D-PLEX100 (GlobeNewswire)
Sep-03-25 08:30AM	PolyPid to Participate in the Upcoming 27th Annual H.C. Wainwright Global Investment Conference (GlobeNewswire)
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Sep-02-25 08:30AM	PolyPid to Present at the 14th Meeting of the Israel Controlled Release Society Conference (GlobeNewswire)
Aug-14-25 03:08AM	PolyPid Ltd (PYPD) Q2 2025 Earnings Call Highlights: Strategic Advances Amid Rising Expenses (GuruFocus.com)
Aug-13-25 07:30AM	PolyPid Provides Corporate Update and Reports Second Quarter 2025 Financial Results (GlobeNewswire)
Aug-12-25 08:00AM	PolyPid Appoints Dr. Nurit Tweezer-Zaks as Chief Medical Officer (GlobeNewswire) +5.88%
Jul-30-25 08:00AM	PolyPid to Report Second Quarter 2025 Financial Results and Operational Highlights on August 13, 2025 (GlobeNewswire)
Jul-15-25 10:00AM	Finance Herald Publishes Coverage of PolyPid's Groundbreaking New 60-Day GLP-1 Delivery Tech (GlobeNewswire)
08:00AM	PolyPid Unveils a Long-Acting GLP-1 Receptor Agonists Delivery Platform Targeting the Diabetes and Weight Loss Market (GlobeNewswire)
Jun-22-25 06:15AM	Analysts Predict Up to ~590% Spike for These 2 Strong Buy Penny Stocks (TipRanks)
Jun-16-25 07:20PM	PolyPid Secures $26.7 Million Through Warrant Exercise Following Successful SHIELD II Phase 3 Trial Results (GlobeNewswire) +7.62%
Jun-09-25 12:53PM	Nano-Cap PolyPid's Lead Drug Candidate Cuts Surgical Infection Risk by 38% In Phase 3 Trial (Benzinga)
07:30AM	PolyPid Announces Positive Topline Results from Phase 3 SHIELD II Trial: D-PLEX100 Demonstrated Significant Reduction in Surgical Site Infections and Successfully Met Primary and All Key Secondary Endpoints (GlobeNewswire)
Jun-06-25 04:05PM	PolyPid to Host Conference Call and Webcast to Discuss D-PLEX100 SHIELD II Phase 3 Trial Topline Results on Monday, June 9, 2025 (GlobeNewswire)
09:40AM	Salesforce initiated, Dollar Tree upgraded: Wall Streets top analyst calls (TipRanks)
May-20-25 07:00AM	PolyPid to Participate in the Lytham Partners Spring 2025 Investor Conference on May 29, 2025 (GlobeNewswire)
May-15-25 03:10AM	PolyPid Ltd (PYPD) Q1 2025 Earnings Call Highlights: Strategic Advances Amid Financial Challenges (GuruFocus.com)
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May-14-25 07:00AM	PolyPid Provides Corporate Update and Reports First Quarter 2025 Financial Results (GlobeNewswire) +7.01%
Apr-29-25 07:00AM	PolyPid to Report First Quarter 2025 Financial Results and Operational Highlights on May 14, 2025 (GlobeNewswire)
Apr-22-25 07:00AM	PolyPid to Participate in The Citizens Life Sciences Conference (GlobeNewswire)
Mar-18-25 03:30PM	Q1 Virtual Investor Summit: On-Demand Presentations Now Live (ACCESS Newswire)
Mar-11-25 07:00AM	PolyPid Announces Successful Completion of Enrollment in Phase 3 SHIELD II Trial of D-PLEX for the Prevention of Abdominal Colorectal Surgical Site Infections (GlobeNewswire)
Mar-03-25 07:00AM	PolyPid to Participate in the 37th Annual ROTH Conference (GlobeNewswire) -8.29%
Feb-13-25 02:09AM	PolyPid Ltd (PYPD) Q4 2024 Earnings Call Highlights: Strategic Advances Amid Rising R&D Costs (GuruFocus.com)
Feb-12-25 07:00AM	PolyPid Provides Corporate Update and Reports Fourth Quarter and Full-Year 2024 Financial Results (GlobeNewswire)
Jan-30-25 07:00AM	PolyPid to Participate in the Oppenheimer 35th Annual Healthcare Life Sciences Conference (GlobeNewswire)
Jan-29-25 07:00AM	PolyPid to Report Fourth Quarter and Full-Year 2024 Financial Results and Operational Highlights on February 12, 2025 (GlobeNewswire)
Dec-23-24 07:22PM	PolyPid Announces Positive Recommendation by DSMB to Continue Enrollment of Phase 3 SHIELD II Trial of D-PLEX to 800 Patients with a Concurrent Private Placement of up to $41 Million (GlobeNewswire) +14.29% -19.29%
Dec-12-24 07:16AM	PolyPid announces research, development collaboration with ImmunoGenesis (TipRanks) -7.53%
Dec-11-24 07:00AM	PolyPid Announces Research and Development Collaboration with ImmunoGenesis Leveraging PLEX Technology to Enhance Cancer Immunotherapy (GlobeNewswire)
Nov-29-24 01:05PM	PolyPid Announces Receipt of Nasdaq Notification of Minimum Stockholders' Equity Non-Compliance (GlobeNewswire)
Nov-14-24 02:08AM	PolyPid Ltd (PYPD) Q3 2024 Earnings Call Highlights: Strategic Advances Amid Financial Challenges (GuruFocus.com)
Nov-13-24 07:00AM	PolyPid Provides Corporate Update and Reports Third Quarter 2024 Financial Results (GlobeNewswire)
Nov-07-24 07:00AM	PolyPid to Participate in the Craig-Hallum 15th Annual Alpha Select Conference (GlobeNewswire)
Oct-30-24 08:00AM	PolyPid to Report Third Quarter 2024 Financial Results and Operational Highlights on November 13, 2024 (GlobeNewswire)
Oct-23-24 07:01PM	Rosalind Advisors, Inc. Reduces Stake in PolyPid Ltd (GuruFocus.com) +5.59%
Oct-21-24 07:00AM	PolyPid Announces Publication in International Journal of Surgery Highlighting Results of Phase 3 SHIELD I Trial of D-PLEX in Prevention of Surgical Site Infections in Abdominal Colorectal Surgery (GlobeNewswire) -8.08%
Oct-01-24 07:00AM	PolyPid Announces Last Patient In for Planned Unblinded Interim Analysis in the Ongoing SHIELD II Phase 3 Trial Evaluating D-PLEX for the Prevention of Abdominal Colorectal Surgical Site Infections (GlobeNewswire)
Sep-03-24 07:00AM	PolyPid to Participate in Three Upcoming Fall Investor Conferences (GlobeNewswire)
Aug-14-24 07:00AM	PolyPid Provides Corporate Update and Reports Second Quarter 2024 Financial Results (GlobeNewswire)
Aug-01-24 08:31PM	PolyPid Announces Private Placement for Up to $14 Million in Gross Proceeds (GlobeNewswire)
Jul-31-24 07:00AM	PolyPid to Report Second Quarter 2024 Financial Results and Operational Highlights on August 14, 2024 (GlobeNewswire)
Jun-18-24 07:00AM	PolyPid Hosts KOL Call to Discuss Significant Unmet Medical Need in Surgical Site Infections Prevention and Provides Update on its Ongoing SHIELD II Phase 3 Trial (GlobeNewswire)
Jun-10-24 07:00AM	PolyPid to Host Virtual KOL Event on June 17, 2024, and Provide an Update on the Company's Ongoing D-PLEX100 Phase 3 Trial (GlobeNewswire)
May-10-24 05:25PM	PolyPid Ltd. (NASDAQ:PYPD) Q1 2024 Earnings Call Transcript (Insider Monkey) +5.39% -8.22%
May-08-24 11:56AM	PYPD Stock Earnings: PolyPid Beats EPS for Q1 2024 (InvestorPlace) -11.32%
07:00AM	PolyPid Provides Corporate Update and Reports First Quarter 2024 Financial Results (GlobeNewswire)
May-01-24 07:00AM	PolyPid to Participate in Citizens JMP Life Sciences Conference (GlobeNewswire)
Apr-30-24 07:00AM	PolyPid Announces Enrollment of 200th Patient in Ongoing SHIELD II Phase 3 Trial Evaluating D-PLEX for the Prevention of Abdominal Colorectal Surgical Site Infections (GlobeNewswire)
Apr-24-24 07:00AM	PolyPid to Report First Quarter 2024 Financial Results and Operational Highlights on May 8, 2024 (GlobeNewswire)
Feb-28-24 07:00AM	PolyPid to Participate in Barclays 26th Annual Global Healthcare Conference (GlobeNewswire) +8.68%
Feb-19-24 12:00PM	PolyPid Ltd. (PYPD) Upgraded to Buy: What Does It Mean for the Stock? (Zacks)
Feb-15-24 09:41AM	PolyPid Ltd. (NASDAQ:PYPD) Q4 2023 Earnings Call Transcript (Insider Monkey)
Feb-14-24 07:00AM	PolyPid Provides Corporate Update and Reports Fourth Quarter and Full Year 2023 Financial Results (GlobeNewswire) -8.21%
Feb-12-24 07:00AM	PolyPid Announces Enrollment of the 100th Patient in the Ongoing SHIELD II Phase 3 Trial (GlobeNewswire)
Jan-31-24 07:00AM	PolyPid to Report Fourth Quarter and Full-Year 2023 Financial Results and Operational Highlights on February 14, 2024 (GlobeNewswire)
Jan-04-24 04:32PM	PolyPid Announces Private Placement for $16 Million in Gross Proceeds (GlobeNewswire) -5.67% +16.36%
Nov-12-23 10:40AM	PolyPid Ltd. (NASDAQ:PYPD) Q3 2023 Earnings Call Transcript (Insider Monkey)
Nov-08-23 07:00AM	PolyPid Provides Corporate Update and Reports Third Quarter 2023 Financial Results (GlobeNewswire)
Nov-07-23 07:00AM	PolyPid Announces the Addition of Dr. Nurit Tweezer-Zaks to its Board of Directors (GlobeNewswire) +7.88%
Nov-01-23 07:00AM	PolyPid to Report Third Quarter 2023 Financial Results and Operational Highlights on November 8, 2023 (GlobeNewswire)
Oct-11-23 07:00AM	PolyPid Regains Compliance with Nasdaq Minimum Closing Bid Price Rule (GlobeNewswire)
Oct-09-23 07:00AM	PolyPid Announces Presentation at the American College of Surgeons Clinical Congress 2023 (GlobeNewswire)
Oct-04-23 07:00AM	PolyPid Announces Publication of Preclinical Data Further Supporting the Good Safety Profile of D-PLEX and PLEX Technology Platform (GlobeNewswire)
Sep-22-23 07:00AM	PolyPid to Present at the 2023 Cantor Fitzgerald Global Healthcare Conference (GlobeNewswire) -9.24%
Sep-21-23 07:34AM	PolyPid Announces Successful Commercial Good Manufacturing Practice (GMP) Audit by Israeli Ministry of Health (GlobeNewswire) -11.74%
Sep-20-23 09:15AM	PolyPid Announces Reverse Share Split (GlobeNewswire) +22.06%
Sep-19-23 07:00AM	PolyPid Announces Successful Completion of Manufacturing Process Validation for D-PLEX (GlobeNewswire) -10.00%
Aug-09-23 07:00AM	PolyPid Provides Corporate Update and Reports Second Quarter 2023 Financial Results (GlobeNewswire) -11.73%
Jul-26-23 07:00AM	PolyPid to Report Second Quarter 2023 Financial Results and Operational Highlights on August 9, 2023 (GlobeNewswire)
Jun-29-23 08:00AM	PolyPid Announces New Publication Highlighting Potent Antibacterial Activity of D-PLEX against Susceptible and Resistant Bacteria for the Prevention of Surgical Site Infections (GlobeNewswire)
Jun-22-23 07:00AM	PolyPid Announces Recruitment of First Patient in Revised SHIELD II Phase 3 Trial Evaluating D-PLEX for Prevention of Abdominal Colorectal Surgical Site Infections (GlobeNewswire)
Jun-05-23 04:02PM	PolyPid Announces 180-Day Extension to Regain Compliance with Nasdaq Minimum Bid Requirement and Transfer of its Listing to the Nasdaq Capital Market (GlobeNewswire)
May-22-23 09:00AM	PolyPid Announces FDA Agreement on the Design of SHIELD II Phase 3 Trial Evaluating D-PLEX for Prevention of Abdominal Colorectal Surgical Site Infections (GlobeNewswire) -6.26%
May-13-23 12:30PM	PolyPid Ltd. (NASDAQ:PYPD) Q1 2023 Earnings Call Transcript (Insider Monkey)
May-10-23 07:00AM	PolyPid Provides Corporate Update and Reports First Quarter 2023 Financial Results (GlobeNewswire)
May-09-23 07:15AM	Sidoti's Micro-Cap Virtual May Conference (ACCESSWIRE)
Apr-26-23 07:00AM	PolyPid to Report First Quarter 2023 Financial Results and Operational Highlights on May 10, 2023 (GlobeNewswire)
Apr-24-23 07:00AM	PolyPid to Participate in Upcoming Investor Conferences (GlobeNewswire)
Apr-14-23 04:01PM	PolyPid Announces Receipt of Nasdaq Notification of Minimum Stockholders Equity Non-Compliance (GlobeNewswire) +5.01%
Mar-31-23 12:00PM	PolyPid Announces Closing of Underwritten Public Offering, Including Full Exercise of Overallotment Option, and Concurrent Private Placement with $11.4 Million in Aggregate Gross Proceeds (GlobeNewswire) +6.26%
Mar-29-23 07:59AM	PolyPid Announces Pricing of $6.2 Million Underwritten Public Offering of Ordinary Shares and Concurrent $4.4 Million Private Placement of Pre-Funded Warrants (GlobeNewswire) -16.86%
Mar-28-23 04:05PM	PolyPid Announces Proposed Underwritten Public Offering of Ordinary Shares (GlobeNewswire)
Mar-07-23 08:00AM	PolyPid to Present at the Barclays Global Healthcare Conference (GlobeNewswire) +5.34%
Feb-09-23 03:22PM	PolyPid Ltd. (NASDAQ:PYPD) Q4 2022 Earnings Call Transcript (Insider Monkey)
Feb-08-23 07:00AM	PolyPid Provides Corporate Update and Reports Fourth Quarter and Full Year 2022 Financial Results (GlobeNewswire) -12.81%
Jan-31-23 07:00AM	PolyPid to Report Fourth Quarter and Full Year 2022 Financial Results and Operational Highlights on February 8, 2023 (GlobeNewswire)

PolyPid Ltd. operates as a phase 3 biopharma company. Its proprietary PLEX technology pairs with medications, enables precise delivery of drugs at effective release rates, over pre-determined durations ranging from several days to months. The firm's product candidates are designed to address unmet medical needs by delivering active pharmaceutical ingredients, or APIs, locally at predetermined release rates and durations over extended periods ranging from days to several months. The company was founded by Noam Emanuel on February 28, 2008 and is headquartered in Petach Tikva, Israel.

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PYPD

Polypid Ltd

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