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ALMS

Alumis Inc

Dec 05 • 04:00PM ET

11.12

+2.82 33.98 %

Healthcare • Biotechnology • USA • NASD

Peers: AMGN GILD REGN VRTX BIIB MRNA INCY BMY ABBV PFE

| Held by: IWM VTI IBB IWN VXF SCHA VTWO IWC PRFZ VHT

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Index	RUT	P/E	-	EPS (ttm)	-3.85	Insider Own	41.28%	Shs Outstand	97.17M	Perf Week	44.98%
Market Cap	1.16B	Forward P/E	-	EPS next Y	-3.16	Insider Trans	7.00%	Shs Float	61.30M	Perf Month	143.33%
Enterprise Value	820.93M	PEG	-	EPS next Q	-0.95	Inst Own	47.01%	Short Float	5.76%	Perf Quarter	157.41%
Income	-245.15M	P/S	52.48	EPS this Y	71.87%	Inst Trans	-0.01%	Short Ratio	4.43	Perf Half Y	209.75%
Sales	22.12M	P/B	3.02	EPS next Y	-8.30%	ROA	-54.44%	Short Interest	3.53M	Perf YTD	41.48%
Book/sh	3.69	P/C	3.07	EPS next 5Y	35.43%	ROE	-66.88%	52W High	10.49 6.01%	Perf Year	29.91%
Cash/sh	3.62	P/FCF	-	EPS past 3/5Y	-58.27% -	ROIC	-58.63%	52W Low	2.76 302.88%	Perf 3Y	-
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	- -	Gross Margin	84.41%	Volatility	13.25% 10.07%	Perf 5Y	-
Dividend TTM	-	EV/Sales	37.11	EPS Y/Y TTM	13.80%	Oper. Margin	-1994.85%	ATR (14)	0.68	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	6.01	Sales Y/Y TTM	-	Profit Margin	-1108.24%	RSI (14)	92.53	Recom	1.12
Dividend Gr. 3/5Y	- -	Current Ratio	6.01	EPS Q/Q	37.84%	SMA20	63.72%	Beta	-1.91	Target Price	19.00
Payout	-	Debt/Eq	0.10	Sales Q/Q	-	SMA50	105.74%	Rel Volume	5.46	Prev Close	8.30
Employees	168	LT Debt/Eq	0.09	Earnings	Nov 13 AMC	SMA200	136.31%	Avg Volume	796.64K	Price	11.12
IPO	Jun 28, 2024	Option/Short	Yes / Yes	EPS/Sales Surpr.	-3.03% -6.08%	Trades		Volume	4,347,021	Change	33.98%

Date	Action	Analyst	Rating Change	Price Target Change
Jul-25-25	Initiated	Wells Fargo	Overweight	$17
Jun-10-25	Resumed	Guggenheim	Buy	$18
Jan-30-25	Initiated	Oppenheimer	Outperform	$32
Oct-31-24	Initiated	Robert W. Baird	Outperform	$25
Oct-17-24	Initiated	H.C. Wainwright	Buy	$30
Jul-23-24	Initiated	Morgan Stanley	Overweight	$36
Jul-23-24	Initiated	Leerink Partners	Outperform	$29
Jul-23-24	Initiated	Guggenheim	Buy	$32
Jul-23-24	Initiated	Cantor Fitzgerald	Overweight

Nov-13-25 04:15PM	Alumis Reports Third Quarter 2025 Financial Results and Highlights Recent Progress (GlobeNewswire)
Nov-04-25 08:00AM	Alumis to Participate in Upcoming November Investor Conferences (GlobeNewswire)
Aug-29-25 07:00AM	Alumis to Participate in Upcoming September Investor Conferences (GlobeNewswire)
Aug-13-25 04:05PM	Alumis Reports Second Quarter 2025 Financial Results and Provides Corporate Update (GlobeNewswire)
Aug-05-25 05:31PM	TYK2 Inhibitors Market to Drive Enormous Growth by 2034 Due to Strong Pipeline and Expanding Indications \| DelveInsight (PR Newswire)
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Jul-29-25 10:23AM	Alumis (ALMS) Merges with ACELYRIN (Insider Monkey)
Jul-24-25 07:30AM	Alumis Completes Patient Enrollment in the Global LUMUS Phase 2b Trial of ESK-001, a Next-Generation Oral TYK2 Inhibitor for the Treatment of Systemic Lupus Erythematosus (GlobeNewswire)
Jul-14-25 04:05PM	Alumis Announces the Promotion of Sanam Pangali to Chief Legal Officer and Corporate Secretary (GlobeNewswire)
May-30-25 05:23AM	Alumis concludes enrolment in Phase III programme of plaque psoriasis therapy (Clinical Trials Arena) -10.49%
May-29-25 04:15PM	Alumis to Present at the Jefferies Global Healthcare Investor Conference (GlobeNewswire)
07:55AM	Alumis Completes Enrollment of Pivotal Phase 3 ONWARD Clinical Program of Lead Candidate ESK-001, a Highly Selective, Next-Generation Oral TYK2 Inhibitor for the Treatment of Moderate-to-Severe Plaque Psoriasis (GlobeNewswire)
May-21-25 09:10AM	Alumis Completes Merger with ACELYRIN (GlobeNewswire)
May-14-25 04:05PM	Alumis Reports First Quarter 2025 Financial Results and Highlights Recent Achievements (GlobeNewswire) +18.63%
May-13-25 01:00PM	Alumis Stockholders Approve Merger with ACELYRIN (GlobeNewswire) -15.05%
01:00PM	ACELYRIN Stockholders Approve Merger with Alumis to Create Clinical Biopharma Company Dedicated to Innovating, Developing and Commercializing Transformative Therapies for Immune-mediated Diseases (GlobeNewswire)
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May-06-25 04:30PM	Leading Independent Proxy Advisory Firm ISS Recommends ACELYRIN Stockholders Vote FOR the Proposed Transaction with Alumis (GlobeNewswire) +10.11%
May-02-25 01:45PM	Acelyrin urges stockholders to vote for proposed merger with Alumis (TipRanks) +19.84%
May-01-25 01:30PM	ACELYRIN Reiterates Benefits of Value-Maximizing Combination with Alumis (GlobeNewswire) -7.49%
Apr-29-25 01:22PM	Acelyrin should liquidate instead of merging with Alumis, investor says (BioPharma Dive) +5.10%
Apr-21-25 06:30AM	Alumis and ACELYRIN Announce Amended Merger Agreement (GlobeNewswire) -6.00%
Apr-10-25 07:00AM	3 Biopharmaceutical Stocks Bucking the Sell-Off (MarketBeat) -15.05%
Apr-07-25 01:43PM	Alumis: Biotech's Stock Gains >100% In A Month - But Risk Of Failure Is High (Seeking Alpha)
Apr-04-25 04:34PM	Alumis and ACELYRIN File Joint Definitive Proxy Statement for Proposed Merger (GlobeNewswire) +17.68%
Mar-25-25 10:51AM	Alumis and Kaken sign agreement in Japan to develop ESK-001 (Pharmaceutical Technology) +5.96%
02:30AM	Alumis and Kaken Pharmaceutical Announce Collaboration and Licensing Agreement for ESK-001 in Dermatology in Japan (GlobeNewswire)
Mar-21-25 07:08AM	Why Alumis Inc. (ALMS) Went Down On Thursday? (InsiderMonkey) +5.04%
Mar-19-25 04:05PM	Alumis Reports Year End 2024 Financial Results and Highlights Recent Achievements (GlobeNewswire) -18.31%
Mar-10-25 08:00AM	Alumis to Present at Leerink's 2025 Global Healthcare Conference (GlobeNewswire)
Mar-08-25 09:00AM	Late-Breaking ESK-001 Phase 2 OLE Data Presented at 2025 AAD Annual Meeting Demonstrate Robust Clinical Responses Over 52-Weeks in Psoriasis (GlobeNewswire)
Mar-04-25 09:01AM	Alumis and ACELYRIN Reaffirm Strategic and Financial Rationale of Proposed Merger (GlobeNewswire)
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09:01AM	ACELYRIN and Alumis Reaffirm Strategic and Financial Rationale of Proposed Merger (GlobeNewswire)
09:00AM	ACELYRIN Determines Unsolicited Indication of Interest From Concentra Biosciences Not Reasonably Expected to Result in a Superior Proposal to Planned Alumis Merger (GlobeNewswire)
Feb-28-25 09:08AM	Alumis Announces Late-Breaker Psoriasis Presentation of 52-week Phase 2 OLE Data for ESK-001 at 2025 American Academy of Dermatology Annual Meeting and Accelerated Topline Phase 3 Data Readout (GlobeNewswire)
Feb-27-25 04:15PM	Alumis Presents Additional Phase 1 Data at ACTRIMS Forum 2025 Supporting Potential of A-005 as First-in-Class CNS Penetrant TYK2 Inhibitor for Treatment of Neuroinflammatory and Neurodegenerative Diseases (GlobeNewswire)
Feb-20-25 09:00PM	ACELYRIN Confirms Receipt of Unsolicited Indication of Interest from Concentra Biosciences (GlobeNewswire)
Feb-10-25 04:45PM	Alumis to Present at Oppenheimer 35th Annual Healthcare Life Sciences Conference (GlobeNewswire) -14.99%
Feb-07-25 10:44AM	Alumis and Acelyrin sign merger agreement (Pharmaceutical Technology) -13.96%
03:00AM	Immune drugmakers Alumis and Acelyrin to merge (BioPharma Dive)
Feb-06-25 04:15PM	Alumis and ACELYRIN to Merge Creating a Late-Stage Clinical Biopharma Company Dedicated to Innovating, Developing and Commercializing Transformative Therapies for Immune-mediated Diseases (GlobeNewswire) -7.57%
Jan-30-25 02:48PM	Why Alumis (ALMS) Stock Is Advancing Today (Insider Monkey)
Jan-28-25 08:00AM	Alumis Strengthens Leadership Team with Key Appointments (GlobeNewswire)
Dec-19-24 08:00AM	Alumis Announces Positive Phase 1 Data for CNS Penetrant TYK2 Inhibitor, A-005 (GlobeNewswire)
Nov-14-24 04:05PM	Alumis Presents Data Highlighting ESK-001's Potential as a High-efficacy Oral Treatment for Systemic Lupus Erythematosus (SLE) at ACR Convergence 2024 (GlobeNewswire) -12.95% -5.95%
Nov-13-24 04:05PM	Alumis Reports Third Quarter 2024 Financial Results and Highlights Recent Achievements (GlobeNewswire)
Nov-04-24 08:00AM	Alumis to Participate in Guggenheim's Inaugural Healthcare Innovation Conference (GlobeNewswire)
Sep-27-24 09:00AM	Late-Breaking Data at EADV of ESK-001, an Oral TYK2 Inhibitor for the Treatment of Psoriasis, Demonstrate Significant Responses with Sustained Increases Over 28 Weeks in Phase 2 OLE Study (GlobeNewswire) -6.77%
Sep-03-24 04:29PM	Alumis to Participate in Upcoming September Investor Conferences (GlobeNewswire)
Aug-13-24 04:05PM	Alumis Reports Second Quarter 2024 Financial Results and Highlights Recent Development and Corporate Achievements (GlobeNewswire)
Jul-29-24 08:00AM	Alumis Initiates ONWARD Phase 3 Clinical Program Evaluating ESK-001, an Oral TYK2 Inhibitor, in Moderate-to-Severe Plaque Psoriasis (GlobeNewswire)
Jun-27-24 11:57PM	Alumis Announces Pricing of Initial Public Offering (GlobeNewswire)

Alumis, Inc. is a clinical stage biopharmaceutical company, which engages in identifying, acquiring, and accelerating the development and commercialization of transformative medicines for autoimmune disorders. It focuses on building a pipeline of molecules with the potential to address a broad range of immune-mediated diseases such as monotherapy or combination therapies. The company was founded on January 29, 2021 and is headquartered in San Francisco, CA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
AKKARAJU SRINIVAS	Director	Dec 03 '25	Buy	7.75	100,000	775,000	1,012,849	Dec 04 08:11 PM
AKKARAJU SRINIVAS	Director	Dec 02 '25	Buy	7.55	96,000	724,800	912,849	Dec 04 08:11 PM
AKKARAJU SRINIVAS	Director	Dec 04 '25	Buy	8.18	66,027	540,101	1,078,876	Dec 04 08:11 PM
AKKARAJU SRINIVAS	Director	Dec 01 '25	Buy	7.46	86,350	644,171	816,849	Dec 01 06:09 PM
AKKARAJU SRINIVAS	Director	Nov 26 '25	Buy	7.64	48,537	370,823	691,797	Dec 01 06:09 PM
AKKARAJU SRINIVAS	Director	Nov 28 '25	Buy	7.64	38,702	295,683	730,499	Dec 01 06:09 PM
Foresite Capital Management VI	10% Owner	Nov 21 '25	Buy	7.38	72,212	532,925	2,614,215	Nov 25 04:02 PM
Tananbaum James B.	Director	Nov 21 '25	Buy	7.38	72,212	532,925	2,614,215	Nov 25 04:02 PM
Foresite Labs, LLC	10% Owner	Nov 21 '25	Buy	7.38	72,212	532,925	2,614,215	Nov 25 04:01 PM
AKKARAJU SRINIVAS	Director	Nov 20 '25	Buy	7.20	125,743	905,350	643,260	Nov 24 06:50 PM
Foresite Labs, LLC	10% Owner	Nov 19 '25	Buy	6.56	190,500	1,249,680	2,542,003	Nov 19 08:54 PM
Foresite Labs, LLC	10% Owner	Nov 17 '25	Buy	5.59	200,000	1,118,500	2,234,129	Nov 19 08:54 PM
Foresite Labs, LLC	10% Owner	Nov 18 '25	Buy	6.19	117,374	726,545	2,351,503	Nov 19 08:54 PM
Foresite Capital Management VI	10% Owner	Nov 19 '25	Buy	6.56	190,500	1,249,680	2,542,003	Nov 19 08:52 PM
Foresite Capital Management VI	10% Owner	Nov 17 '25	Buy	5.59	200,000	1,118,500	2,234,129	Nov 19 08:52 PM
Foresite Capital Management VI	10% Owner	Nov 18 '25	Buy	6.19	117,374	726,545	2,351,503	Nov 19 08:52 PM
Tananbaum James B.	Director	Nov 19 '25	Buy	6.56	190,500	1,249,680	2,542,003	Nov 19 08:51 PM
Tananbaum James B.	Director	Nov 17 '25	Buy	5.59	200,000	1,118,500	2,234,129	Nov 19 08:51 PM
Tananbaum James B.	Director	Nov 18 '25	Buy	6.19	117,374	726,545	2,351,503	Nov 19 08:51 PM
AKKARAJU SRINIVAS	Director	Nov 19 '25	Buy	6.56	137,772	903,784	517,517	Nov 19 08:46 PM
AKKARAJU SRINIVAS	Director	Nov 18 '25	Buy	6.05	102,652	621,045	379,745	Nov 19 08:46 PM
AKKARAJU SRINIVAS	Director	Nov 17 '25	Buy	5.51	914	5,036	277,093	Nov 19 08:46 PM
AKKARAJU SRINIVAS	Director	Nov 13 '25	Buy	5.25	276,179	1,449,940	276,179	Nov 17 04:59 PM
Tananbaum James B.	Director	May 02 '25	Buy	4.62	25,000	115,500	4,227,670	May 06 09:48 PM
Tananbaum James B.	Director	May 06 '25	Buy	4.34	20,000	86,800	4,247,670	May 06 09:48 PM
Foresite Labs, LLC	10% Owner	May 02 '25	Buy	4.62	25,000	115,500	4,227,670	May 06 09:48 PM
Foresite Labs, LLC	10% Owner	May 06 '25	Buy	4.34	20,000	86,800	4,247,670	May 06 09:48 PM
Foresite Capital Management VI	10% Owner	May 02 '25	Buy	4.62	25,000	115,500	4,227,670	May 06 09:47 PM
Foresite Capital Management VI	10% Owner	May 06 '25	Buy	4.34	20,000	86,800	4,247,670	May 06 09:47 PM
AKKARAJU SRINIVAS	Director	May 05 '25	Buy	4.67	160,370	749,676	3,586,788	May 06 06:52 PM
AKKARAJU SRINIVAS	Director	May 02 '25	Buy	4.55	159,920	727,636	3,426,418	May 06 06:52 PM
Colowick Alan	Director	Apr 01 '25	Buy	6.97	16,104	112,309	16,104	Apr 03 06:05 PM
Colowick Alan	Director	Apr 02 '25	Buy	7.49	2,300	17,235	18,404	Apr 03 06:05 PM
Babler Martin	President, CEO and Chairman	Apr 01 '25	Buy	6.44	15,650	100,733	106,454	Apr 03 06:05 PM

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ALMS

Alumis Inc

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