REGN Regeneron Pharmaceuticals, Inc. Stock Quote

REGN [NASD]

Index	S&P 500	P/E	11.50	EPS (ttm)	55.71	Insider Own	1.60%	Shs Outstand	105.00M	Perf Week	0.21%
Market Cap	68.68B	Forward P/E	14.79	EPS next Y	43.32	Insider Trans	-23.86%	Shs Float	102.21M	Perf Month	-2.25%
Income	6.21B	PEG	2.88	EPS next Q	9.30	Inst Own	89.00%	Short Float	1.33%	Perf Quarter	19.96%
Sales	12.38B	P/S	5.55	EPS this Y	65.30%	Inst Trans	2.44%	Short Ratio	1.75	Perf Half Y	32.63%
Book/sh	144.07	P/B	4.45	EPS next Y	-25.41%	ROA	34.20%	Target Price	677.04	Perf Year	15.43%
Cash/sh	36.49	P/C	17.56	EPS next 5Y	4.00%	ROE	51.40%	52W Range	441.00 - 686.62	Perf YTD	32.66%
Dividend	-	P/FCF	40.56	EPS past 5Y	40.80%	ROI	23.90%	52W High	-6.66%	Beta	0.17
Dividend %	-	Quick Ratio	3.20	Sales past 5Y	15.70%	Gross Margin	86.80%	52W Low	45.33%	ATR	16.52
Employees	9123	Current Ratio	3.60	Sales Q/Q	163.20%	Oper. Margin	53.90%	RSI (14)	46.98	Volatility	2.03% 2.37%
Optionable	Yes	Debt/Eq	0.18	EPS Q/Q	267.50%	Profit Margin	50.10%	Rel Volume	0.81	Prev Close	651.88
Shortable	Yes	LT Debt/Eq	0.13	Earnings	Aug 05 BMO	Payout	0.00%	Avg Volume	775.91K	Price	640.89
Recom	2.00	SMA20	-3.35%	SMA50	2.79%	SMA200	20.92%	Volume	666,652	Change	-1.69%

Jun-29-21

Initiated

H.C. Wainwright

Buy

$703

Jan-25-21

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BMO Capital Markets

Market Perform → Outperform

$630

Jan-13-21

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The Benchmark Company

Hold → Buy

$590

Jan-08-21

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Citigroup

Neutral → Buy

$635 → $575

Oct-05-20

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Cantor Fitzgerald

Neutral → Overweight

$690

Aug-20-20

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The Benchmark Company

Buy → Hold

Jul-09-20

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SunTrust

Hold → Buy

$400 → $750

May-26-20

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Wells Fargo

Equal Weight → Overweight

$559 → $734

Apr-28-20

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Citigroup

Buy → Neutral

$540 → $575

Apr-17-20

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The Benchmark Company

Hold → Buy

$655

Apr-08-20

Initiated

The Benchmark Company

Hold

Mar-31-20

Initiated

Wolfe Research

Peer Perform

Feb-27-20

Initiated

Barclays

Overweight

$530

Feb-26-20

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Canaccord Genuity

Hold → Buy

$550

Feb-26-20

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Robert W. Baird

Outperform → Neutral

$410

Feb-25-20

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Jefferies

Hold → Buy

$355 → $492

Feb-11-20

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Argus

Hold → Buy

$430

Dec-24-19

Initiated

Raymond James

Mkt Perform

Dec-16-19

Downgrade

Evercore ISI

Outperform → In-line

Dec-13-19

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Credit Suisse

Neutral → Outperform

$400

Sep-21-21 12:59AM	New Dupixent® (dupilumab) Data in Patients as Young as Six Years Old With Moderate-to-Severe Atopic Dermatitis to Be Presented at WCPD and EADV PR Newswire
Sep-20-21 05:50PM	Regeneron (REGN) Stock Moves -1.69%: What You Should Know Zacks
01:42PM	Early tests show Pfizers Covid-19 vaccine for kids ages 5 to 11 is very safe: Epidemiologist Yahoo Finance Video
06:45AM	Sanofi, Regeneron, Share Competitive Libtayo Survival Data in 1L NSCLC Benzinga
Sep-19-21 11:30AM	ESMO Late-breaking Data Show Libtayo® (cemiplimab) and Chemotherapy First-line Treatment Combination Significantly Improved Overall Survival in Patients with Advanced NSCLC PR Newswire
Sep-18-21 05:57AM	AbbVie's Pain Is Sanofi's and Regeneron's Gain Motley Fool
Sep-17-21 03:59PM	FDA advisory panel votes against approving COVID-19 booster Yahoo Finance Video
03:56PM	Wearing masks is something we should consider possibly in every flu, winter season: Doctor Yahoo Finance Video
02:09PM	Doctor: This conversation about boosters doesnt take place just in the U.S. Yahoo Finance Video
12:12PM	Regeneron Pharmaceuticals (NASDAQ:REGN) Seems To Use Debt Rather Sparingly Simply Wall St.
Sep-16-21 11:28AM	Regeneron, Lilly Get New COVID Drug Deals From Government Zacks
08:39AM	Company News for Sep 16, 2021 Zacks
06:00AM	Smart Investors Are Watching This Trend Right Now Motley Fool
Sep-15-21 01:51PM	Doctor on Bidens vaccine mandate: Extraordinary times call for extraordinary measures Yahoo Finance Video
12:24PM	Dow Jones Rises But Nasdaq Lags As Market Seeks Direction; Recent IPOs Lead Growth Stocks Investor's Business Daily
11:30AM	Has Regeneron Pharmaceuticals (REGN) Outpaced Other Medical Stocks This Year? Zacks
09:52AM	Dow Jones Today, Stocks Open Flat With Empire State Data, Goldman/GreenSky Deal, ThoughtWorks IPO And Microsoft Dividend In Focus Investor's Business Daily
07:57AM	After Regeneron, US Government Orders Additional COVID-19 Therapy From Eli Lilly Benzinga
07:53AM	U.S. Govt Calls For Additional Doses Of Regeneron's COVID-19 Antibody Therapy Benzinga
07:40AM	U.S. to pay $2.9 billion for an additional 1.4 million doses of Regeneron's COVID-19 therapy MarketWatch
07:38AM	The Daily Biotech Pulse: Lilly, Regeneron Ink COVID-19 Drug Deal With US, Regulatory Setback For Calliditas, Theravance To Cut 75% Jobs, 4 IPOs Benzinga
07:27AM	UPDATE 1-U.S. buys additional doses of Eli Lilly, Regeneron COVID-19 therapy Reuters
Sep-14-21 06:06PM	UPDATE 1-U.S. to buy 1.4 mln additional doses of Regeneron's COVID-19 therapy Reuters
05:33PM	Regeneron Announces New U.S. Government Agreement to Purchase Additional Doses of REGEN-COV (casirivimab and imdevimab) Antibody Cocktail PR Newswire
11:27AM	aTyr (LIFE) Surges on Positive Data on Lead Candidate ATYR1923 Zacks
Sep-13-21 05:50PM	Regeneron (REGN) Stock Sinks As Market Gains: What You Should Know Zacks
10:46AM	Endo (ENDP) Gains on Settlement of Opioid Cases in New York for $50M Zacks
Sep-11-21 06:12AM	Can Pfizer Beat Sanofi and Regeneron in the Eczema Market? Motley Fool
Sep-09-21 02:24PM	Covid vaccine potentially causing infertility is a complete myth at this point: Doctor Yahoo Finance Video
Sep-08-21 04:05PM	Regeneron Announces Investor Conference Presentations PR Newswire
01:37PM	If you dont get vaccinated, you will get Covid at this point: Doctor Yahoo Finance Video
Sep-07-21 02:12PM	Vaccination is still working incredibly well as bolstering our immune response to Covid: Doctor Yahoo Finance Video
10:50AM	Will Regeneron's (REGN) Antibody Cocktail Fuel Further Growth? Zacks
09:48AM	Bet on These 5 Low-Beta Stocks to Combat Market Volatility Zacks
09:10AM	3 Hot Stocks to Buy in September Motley Fool
09:06AM	5 Stocks With High ROE as Markets Stumble on Tepid Jobs Report Zacks
Sep-03-21 01:58PM	A large prevalence rate of the virus is going to affect everyone: Doctor Yahoo Finance Video
Sep-02-21 02:18PM	Data is starting to support the need & timeline for a Covid-19 booster vaccine: Virologist Yahoo Finance Video
12:00PM	Merck (MRK) Begins Molnupiravir Study for COVID Prevention Zacks
10:26AM	3 Large Biotech Stocks Worth Adding to Your Portfolio Zacks
06:00AM	Now May Be the Big Moment for These 2 COVID Stocks Motley Fool
Sep-01-21 02:14PM	All the teachers should be mandated now to get the vaccine: Doctor Yahoo Finance Video
10:44AM	Biotech Stock Roundup: REGN Gives Study Update, INCY Wins Drug Approval & More Zacks
Aug-31-21 10:46AM	Regeneron Is More Than a Covid Play. This Drug Could Be the Worlds Biggest Selling by 2030. Barrons.com
Aug-30-21 02:06PM	Early polls & surveys show theres about a 25% likelihood that parents are going to vaccinate their kids: Doctor Yahoo Finance Video
11:30AM	Is Regeneron Pharmaceuticals (REGN) Outperforming Other Medical Stocks This Year? Zacks
11:02AM	BioMarin's (BMRN) Dwarfism Drug Gets Approval in Europe Zacks
10:51AM	Sanofi (SNY)/Regeneron's Dupixent Meets Eczema Study Goal Zacks
07:44AM	UPDATE 2-Pfizer study shows skin disease drug more effective than Regeneron rival Reuters
06:58AM	Dupixent Becomes First Biologic To Show Benefit In Infant Patients With Atopic Dermatitis Benzinga
12:59AM	Dupixent® (dupilumab) Pivotal Trial Meets All Primary and Secondary Endpoints Becoming First Biologic Medicine to Significantly Reduce Signs and Symptoms of Moderate-to-severe Atopic Dermatitis in Children as Young as 6 Months PR Newswire
Aug-27-21 02:07PM	SCAN Health Plan CEO on reducing Covid-19 vaccine disparities among minorities Yahoo Finance Video
12:50PM	Is Regeneron Pharmaceuticals (REGN) A Worthy Investment? Insider Monkey
12:16PM	Bronte Capital on Regeneron (REGN): A Winner in Mouse Genetics Insider Monkey
07:10AM	5 Bigwigs to Buy on Double-Digit Returns in the Past Month Zacks
05:55AM	3 Growth Stocks Near Record Highs That Are Still Worth Buying Motley Fool
Aug-26-21 12:56PM	Biotech Stock Roundup: REGN, MRNA Offer COVID-19 Updates, TBPH Down on Study Update Zacks
Aug-25-21 01:38PM	I am in favor of companies adopting these strong policies about covid vaccination & mandating it: Doctor Yahoo Finance Video
11:31AM	Top Healthcare Stocks for September 2021 Investopedia
11:22AM	Regeneron's (REGN) Wet AMD Study on High Dose Eylea Meets Goal Zacks
07:16AM	6 Must-Buy Corporate Giants As Major Indexes Hit Record High Zacks
Aug-24-21 02:16PM	The covid booster question is one of privilege and we must be very thoughtful about: Doctor Yahoo Finance Video
12:57PM	Regeneron Touts Mid-Stage Win For Higher Dose Of Eylea In Age-related Macular Degeneration Benzinga
09:57AM	Hopes of Moderna (MRNA) Vaccine Approval Boost Biotech Investopedia
07:00AM	Regeneron Announces Encouraging Topline Phase 2 Data of High-dose aflibercept in Wet Age-related Macular Degeneration PR Newswire
Aug-23-21 01:57PM	The FDA approval of Pfizers COVID-19 vaccine is a critical step forward in vaccine confidence: Doctor Yahoo Finance Video
11:20AM	Regeneron (REGN) COVID-19 Antibody Cocktail Gets CMA in the UK Zacks
Aug-20-21 02:54PM	Doctor on U.S. travel amid the pandemic: I wouldnt be surprised if we see more restrictions Yahoo Finance Video
01:56PM	Regeneron Pharmaceutical Stock Earns 84 Relative Strength Rating Investor's Business Daily
09:47AM	UK Approves Regeneron - Roche's COVID-19 Antibody Cocktail Benzinga
09:03AM	5 Stocks With High ROE to Buy Amid Fresh COVID-19 Fears Zacks
09:01AM	J&J (JNJ) CEO Alex Gorsky to Resign, Joaquin Duato to Succeed Zacks
07:00AM	UK Authorizes Regeneron Antibody Cocktail to Prevent and Treat Acute COVID-19 Infection PR Newswire
06:48AM	U.K. approves antibody treatment cocktail for COVID-19 MarketWatch
03:12AM	UPDATE 2-UK approves Regeneron/Roche antibody cocktail for COVID-19 Reuters
Aug-19-21 03:01PM	Why annual COVID-19 booster shots might be unlikely Yahoo Finance Video
11:55AM	Regeneron (REGN) Antibody Cocktail for COVID-19 Gets a Boost Zacks
09:26AM	Why Regeneron Pharmaceuticals (REGN) Isn't Done Growing Earnings Yet Zacks
Aug-18-21 04:11PM	PreMarket Prep Stock Of The Day: Regeneron Benzinga
02:06PM	We cant rest complacently in the shield that the vaccines alone give us: Doctor Yahoo Finance Video
11:50AM	An Intrinsic Calculation For Regeneron Pharmaceuticals, Inc. (NASDAQ:REGN) Suggests It's 27% Undervalued Simply Wall St.
11:03AM	Regeneron Stock Jumps as GOP Governors Boost Its Antibody Therapy Barrons.com
10:32AM	5 Stocks Insiders Are Selling Benzinga
08:59AM	Regeneron Stock Gets Boost From Support of Texas, Florida Governors TheStreet.com
06:50AM	Updating Our Bullish Strategy for Regeneron Pharmaceuticals TheStreet.com
Aug-17-21 08:42PM	Top donor of Floridas Ron DeSantis invests in COVID drug that governor promotes MarketWatch
03:01PM	Jim Cramer: The Fortunes Have Been Restored for Regeneron and Abbott TheStreet.com
06:17AM	Novartis Shares Two Year Beovu Data From Diabetic Macular Edema Studies Benzinga
Aug-16-21 03:53PM	How investors could pose as a headwind for Moderna Yahoo Finance Video
03:02PM	Cramer's Mad Money Recap: Regeneron, Abbott, Nvidia TheStreet.com
01:50PM	U.S. children covid hospitalizations hit highest levels weve ever seen: Doctor Yahoo Finance Video
Aug-14-21 09:01AM	Regeneron's Antibody Cocktail Authorized for Preventing COVID: Why It's Not a Big Deal for the Stock Motley Fool
Aug-13-21 02:05PM	Doctor on COVID: We have to react to the public health information Yahoo Finance Video
Aug-12-21 02:11PM	If fully vaccinated your immunity is higher than someone who's unvaccinated: ER Physician Yahoo Finance Video
11:31AM	Stock Market Today With Jim Cramer: Norwegian Cruise, Regeneron TheStreet.com
11:30AM	Is Regeneron Pharmaceuticals (REGN) Stock Outpacing Its Medical Peers This Year? Zacks
11:05AM	Biotech Stock Roundup: REGN Q2 Earnings Beat, BLUE, BYSI's Updates & More Zacks
Aug-11-21 02:20PM	Doctor: More than 90% of hospitalizations driven by the unvaccinated Yahoo Finance Video
10:11AM	Instead of Panicking About a Market Crash, Do This Motley Fool
Aug-10-21 09:39AM	10 Stocks that Beat Earnings Estimates Insider Monkey

Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines for treating various medical conditions worldwide. The company's products include EYLEA injection to treat wet age-related macular degeneration and diabetic macular edema; myopic choroidal neovascularization; and diabetic retinopathy, as well as macular edema following retinal vein occlusion, including macular edema following central retinal vein occlusion and macular edema following branch retinal vein occlusion. It also provides Dupixent injection to treat atopic dermatitis in adults, and asthma in adults and adolescents; Praluent injection for heterozygous familial hypercholesterolemia or clinical atherosclerotic cardiovascular disease in adults; and Kevzara solution for subcutaneous injection for treating rheumatoid arthritis in adults. In addition, the company offers Libtayo injection to treat metastatic or locally advanced cutaneous squamous cell carcinoma; ARCALYST injection for cryopyrin-associated periodic syndromes, including familial cold auto-inflammatory syndrome and muckle-wells syndrome; and ZALTRAP injection for intravenous infusion to treat metastatic colorectal cancer. Further, it offers Inmazeb injection for infection caused by Zaire ebolavirus; and develops product candidates for treating patients with eye, allergic and inflammatory, cancer, cardiovascular and metabolic, pain, infectious, and other diseases. The company has collaboration and license agreements with Sanofi; Bayer; Teva Pharmaceutical Industries Ltd.; Mitsubishi Tanabe Pharma Corporation; Alnylam Pharmaceuticals, Inc.; Roche Pharmaceuticals; and Kiniksa Pharmaceuticals, Ltd., as well as has an agreement with the U.S. Department of Health and Human Services. It has collaborations with Zai Lab Limited; Intellia Therapeutics, Inc.; and Biomedical Advanced Research Development Authority. Regeneron Pharmaceuticals, Inc. was founded in 1988 and is headquartered in Tarrytown, New York.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
COLES N ANTHONY	Director	Sep 15	Option Exercise	365.99	11,948	4,372,807	12,850	Sep 17 04:01 PM
COLES N ANTHONY	Director	Sep 15	Sale	658.98	11,948	7,873,484	902	Sep 17 04:01 PM
Zoghbi Huda Y	Director	Sep 14	Option Exercise	391.92	998	391,136	1,889	Sep 15 04:03 PM
Zoghbi Huda Y	Director	Sep 14	Sale	650.00	998	648,700	891	Sep 15 04:03 PM
Zoghbi Huda Y	Director	Sep 13	Option Exercise	391.92	2	784	893	Sep 15 04:03 PM
Tessier-Lavigne Marc	Director	Sep 13	Option Exercise	273.67	12,750	3,489,292	14,828	Sep 15 04:02 PM
BROWN MICHAEL S	Director	Sep 13	Option Exercise	405.06	9,704	3,930,684	10,595	Sep 15 04:03 PM
Tessier-Lavigne Marc	Director	Sep 13	Sale	641.71	12,750	8,181,827	2,078	Sep 15 04:02 PM
Zoghbi Huda Y	Director	Sep 13	Sale	651.10	2	1,302	891	Sep 15 04:03 PM
BROWN MICHAEL S	Director	Sep 13	Sale	648.16	9,704	6,289,792	891	Sep 15 04:03 PM
GOLDSTEIN JOSEPH L	Director	Sep 10	Option Exercise	380.95	2,479	944,375	8,370	Sep 13 04:01 PM
GOLDSTEIN JOSEPH L	Director	Sep 10	Sale	650.00	2,479	1,611,350	5,891	Sep 13 04:01 PM
McCourt Marion	EVP Commercial	Sep 01	Option Exercise	342.93	1,000	342,930	18,038	Sep 03 04:03 PM
RYAN ARTHUR F	Director	Sep 01	Sale	676.28	100	67,628	23,291	Sep 03 04:04 PM
McCourt Marion	EVP Commercial	Sep 01	Sale	674.72	1,000	674,720	17,038	Sep 03 04:03 PM
Landry Robert E	EVP Finance CFO	Aug 31	Option Exercise	555.67	1,000	555,670	26,903	Sep 01 04:05 PM
SING GEORGE L	Director	Aug 30	Sale	671.09	550	369,100	750	Aug 30 04:26 PM
SING GEORGE L	Director	Aug 30	Sale	672.50	1,000	672,500	42,858	Aug 30 04:26 PM
POON CHRISTINE A	Director	Aug 27	Option Exercise	57.11	15,000	856,650	16,681	Aug 31 04:03 PM
POON CHRISTINE A	Director	Aug 27	Sale	668.09	15,000	10,021,406	1,681	Aug 31 04:03 PM
SING GEORGE L	Director	Aug 26	Sale	672.00	150	100,800	1,000	Aug 30 04:26 PM
VAGELOS P ROY	Director	Aug 25	Option Exercise	179.13	75,000	13,434,750	366,090	Aug 27 04:01 PM
LAROSA JOSEPH J	EVP General Counsel and Secret	Aug 23	Sale	661.84	3,425	2,266,817	13,182	Aug 24 04:06 PM
Fenimore Christopher R.	SVP Controller	Aug 23	Sale	655.31	4,781	3,133,037	27,739	Aug 24 04:04 PM
Fenimore Christopher R.	SVP Controller	Aug 20	Option Exercise	179.13	13,500	2,418,255	32,520	Aug 24 04:04 PM
LAROSA JOSEPH J	EVP General Counsel and Secret	Aug 20	Option Exercise	179.13	10,000	1,791,300	23,182	Aug 24 04:06 PM
SCHLEIFER LEONARD S	President & CEO	Aug 19	Sale	660.03	10,000	6,600,300	21,178	Aug 20 04:02 PM
COLES N ANTHONY	Director	Aug 18	Option Exercise	345.47	5,100	1,761,897	6,002	Aug 19 04:04 PM
SCHLEIFER LEONARD S	President & CEO	Aug 18	Sale	650.03	200,000	130,006,000	304,746	Aug 20 04:02 PM
VAGELOS P ROY	Director	Aug 18	Sale	650.04	10,039	6,525,752	37,747	Aug 19 04:05 PM
COLES N ANTHONY	Director	Aug 18	Sale	650.00	5,100	3,315,000	902	Aug 19 04:04 PM
COLES N ANTHONY	Director	Aug 17	Option Exercise	345.47	900	310,923	1,802	Aug 19 04:04 PM
COLES N ANTHONY	Director	Aug 17	Sale	650.00	900	585,000	902	Aug 19 04:04 PM
Bassler Bonnie L	Director	Aug 16	Option Exercise	376.69	1,219	459,185	2,110	Aug 17 04:16 PM
YANCOPOULOS GEORGE	President and Chief Scientific	Aug 16	Sale	625.29	49,227	30,781,138	887,483	Aug 17 04:13 PM
SCHLEIFER LEONARD S	President & CEO	Aug 16	Sale	624.36	10,000	6,243,614	31,178	Aug 17 04:42 PM
SING GEORGE L	Director	Aug 16	Sale	627.50	1,000	627,500	2,050	Aug 17 04:17 PM
SING GEORGE L	Director	Aug 16	Sale	630.00	705	444,150	43,858	Aug 17 04:17 PM
Bassler Bonnie L	Director	Aug 16	Sale	630.00	1,219	767,970	891	Aug 17 04:16 PM
COLES N ANTHONY	Director	Aug 13	Option Exercise	345.47	2,000	690,940	2,902	Aug 16 04:04 PM
YANCOPOULOS GEORGE	President and Chief Scientific	Aug 13	Sale	625.00	773	483,125	936,710	Aug 17 04:13 PM
COLES N ANTHONY	Director	Aug 13	Sale	625.00	2,000	1,250,000	902	Aug 16 04:04 PM
SING GEORGE L	Director	Aug 13	Sale	620.00	500	310,000	44,563	Aug 13 05:19 PM
SING GEORGE L	Director	Aug 12	Sale	611.00	1,000	611,000	45,063	Aug 13 05:19 PM
SING GEORGE L	Director	Aug 11	Sale	620.00	300	186,000	3,050	Aug 13 05:19 PM
SING GEORGE L	Director	Aug 11	Sale	620.50	2,000	1,241,000	46,063	Aug 13 05:19 PM
SING GEORGE L	Director	Aug 10	Sale	613.85	2,600	1,596,010	48,063	Aug 10 05:00 PM
Landry Robert E	EVP Finance CFO	Aug 10	Sale	611.90	537	328,593	25,903	Aug 10 05:55 PM
Van Plew Daniel P	EVP & General Mgr, Industrial	Aug 10	Sale	611.86	6,603	4,040,105	26,931	Aug 10 05:54 PM
Van Plew Daniel P	EVP & General Mgr, Industrial	Aug 09	Option Exercise	270.43	25,000	6,760,750	51,931	Aug 10 05:54 PM
Landry Robert E	EVP Finance CFO	Aug 09	Option Exercise	381.92	3,000	1,145,760	28,903	Aug 10 05:55 PM
BROWN MICHAEL S	Director	Aug 09	Sale	612.38	1,687	1,033,085	7,662	Aug 10 05:00 PM
Landry Robert E	EVP Finance CFO	Aug 09	Sale	617.83	364	224,891	25,903	Aug 10 05:55 PM
Landry Robert E	EVP Finance CFO	Aug 06	Option Exercise	381.92	2,000	763,840	27,903	Aug 10 05:55 PM
SCHLEIFER LEONARD S	President & CEO	Aug 06	Option Exercise	52.03	400,000	20,812,000	596,176	Aug 10 05:05 PM
SING GEORGE L	Director	Aug 06	Sale	612.42	350	214,347	3,350	Aug 10 05:00 PM
SING GEORGE L	Director	Aug 06	Sale	611.38	4,000	2,445,520	50,663	Aug 10 05:00 PM
Bassler Bonnie L	Director	Aug 05	Option Exercise	391.92	2,559	1,002,923	3,450	Aug 06 04:02 PM
YANCOPOULOS GEORGE	President and Chief Scientific	Aug 05	Sale	600.06	50,000	30,003,000	937,483	Aug 06 04:03 PM
Bassler Bonnie L	Director	Aug 05	Sale	600.00	2,559	1,535,400	891	Aug 06 04:02 PM
McCourt Marion	EVP Commercial	Aug 02	Option Exercise	342.93	1,000	342,930	18,038	Aug 04 04:03 PM
RYAN ARTHUR F	Director	Aug 02	Sale	577.95	100	57,795	23,391	Aug 04 04:05 PM
McCourt Marion	EVP Commercial	Aug 02	Sale	577.12	1,000	577,120	17,038	Aug 04 04:03 PM
LAROSA JOSEPH J	EVP General Counsel and Secret	Jul 06	Sale	580.00	3,398	1,970,840	13,182	Jul 07 04:01 PM
LAROSA JOSEPH J	EVP General Counsel and Secret	Jul 02	Option Exercise	179.13	10,000	1,791,300	23,182	Jul 07 04:01 PM
RYAN ARTHUR F	Director	Jul 01	Sale	564.50	100	56,450	23,491	Jul 02 04:02 PM
BROWN MICHAEL S	Director	Jun 25	Option Exercise	371.40	2,084	773,998	2,975	Jun 28 04:01 PM
BROWN MICHAEL S	Director	Jun 25	Sale	549.00	2,084	1,144,116	891	Jun 28 04:01 PM
YANCOPOULOS GEORGE	President and Chief Scientific	Jun 21	Sale	538.90	80,000	43,112,141	2,108	Jun 23 04:02 PM
BROWN MICHAEL S	Director	Jun 14	Option Exercise	371.40	1,700	631,380	2,591	Jun 16 04:02 PM
RYAN ARTHUR F	Director	Jun 14	Sale	524.76	100	52,476	23,591	Jun 16 04:03 PM
BROWN MICHAEL S	Director	Jun 14	Sale	525.00	1,700	892,500	891	Jun 16 04:02 PM
GOLDSTEIN JOSEPH L	Director	Jun 07	Option Exercise	374.12	1,930	722,052	7,821	Jun 08 04:03 PM
McCourt Marion	EVP Commercial	Jun 07	Option Exercise	342.93	1,000	342,930	18,038	Jun 08 04:02 PM
McCourt Marion	EVP Commercial	Jun 07	Sale	511.65	1,000	511,650	17,038	Jun 08 04:02 PM
GOLDSTEIN JOSEPH L	Director	Jun 07	Sale	525.00	1,930	1,013,250	5,891	Jun 08 04:03 PM
STAHL NEIL	EVP Research and Development	May 17	Sale	519.46	17,521	9,101,460	24,280	May 18 04:04 PM
STAHL NEIL	EVP Research and Development	May 14	Option Exercise	148.87	52,500	7,815,575	64,280	May 18 04:04 PM
McCourt Marion	EVP Commercial	May 07	Option Exercise	342.93	1,000	342,930	18,038	May 10 04:02 PM
McCourt Marion	EVP Commercial	May 07	Sale	495.63	1,000	495,630	17,038	May 10 04:02 PM
VAGELOS P ROY	Director	Feb 23	Option Exercise	52.03	250,000	13,007,500	487,088	Feb 24 04:02 PM
RYAN ARTHUR F	Director	Feb 01	Sale	506.92	100	50,692	23,691	Feb 02 04:06 PM
BROWN MICHAEL S	Director	Jan 25	Option Exercise	380.95	2,480	944,756	3,371	Jan 27 04:06 PM
BROWN MICHAEL S	Director	Jan 25	Sale	554.32	2,480	1,374,714	891	Jan 27 04:06 PM
RYAN ARTHUR F	Director	Jan 04	Sale	483.60	100	48,360	23,543	Jan 05 04:09 PM
YANCOPOULOS GEORGE	President and Chief Scientific	Dec 30	Option Exercise	52.03	398,079	20,712,050	908,303	Dec 31 05:30 PM
RYAN ARTHUR F	Director	Dec 01	Sale	520.48	100	52,048	23,643	Dec 02 04:09 PM
MURPHY ANDREW J	EVP Research	Nov 17	Sale	542.73	6,628	3,597,188	47,136	Nov 18 04:02 PM
MURPHY ANDREW J	EVP Research	Nov 16	Option Exercise	30.63	13,736	420,734	60,872	Nov 18 04:02 PM
COLES N ANTHONY	Director	Nov 13	Option Exercise	345.47	11	3,800	654	Nov 13 05:57 PM
RYAN ARTHUR F	Director	Nov 02	Sale	548.54	100	54,854	23,743	Nov 03 05:22 PM
MURPHY ANDREW J	EVP Research	Oct 22	Option Exercise	38.56	5,185	199,926	47,136	Oct 23 04:02 PM
McCourt Marion	SVP Commercial	Oct 05	Option Exercise	342.93	1,000	342,930	14,963	Oct 06 04:07 PM
GOLDSTEIN JOSEPH L	Director	Oct 05	Option Exercise	520.01	9,212	4,790,332	14,855	Oct 06 04:09 PM
GOLDSTEIN JOSEPH L	Director	Oct 05	Sale	600.00	9,212	5,527,200	5,643	Oct 06 04:09 PM
McCourt Marion	SVP Commercial	Oct 05	Sale	600.00	1,000	600,000	13,963	Oct 06 04:07 PM
RYAN ARTHUR F	Director	Oct 01	Sale	558.13	100	55,813	28,343	Oct 05 04:13 PM
BROWN MICHAEL S	Director	Sep 22	Option Exercise	378.77	5,090	1,927,917	5,733	Sep 23 04:01 PM
BROWN MICHAEL S	Director	Sep 22	Sale	552.36	1,000	552,360	9,349	Sep 23 04:01 PM
BROWN MICHAEL S	Director	Sep 22	Sale	552.36	5,090	2,811,512	643	Sep 23 04:01 PM

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