SACHS BRUCE I - Insider Transactions

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Ticker	Owner	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
VRTX	SACHS BRUCE I	Director	Nov 06	Option Exercise	127.54	11,250	1,434,825	51,250	Nov 08 04:11 PM
VRTX	SACHS BRUCE I	Director	Nov 06	Sale	385.00	11,250	4,331,250	40,000	Nov 08 04:11 PM
VRTX	SACHS BRUCE I	Director	Jul 17	Option Exercise	127.54	11,250	1,434,825	51,250	Jul 18 04:17 PM
VRTX	SACHS BRUCE I	Director	Jul 17	Sale	356.75	11,250	4,013,459	40,000	Jul 18 04:17 PM
VRTX	SACHS BRUCE I	Director	Apr 12	Option Exercise	72.14	21,300	1,536,582	62,510	Apr 14 04:14 PM

VRTX	SACHS BRUCE I	Director	Apr 12	Sale	326.73	21,300	6,959,422	41,210	Apr 14 04:14 PM
VRTX	SACHS BRUCE I	Director	Jan 31	Option Exercise	72.14	1,200	86,568	42,410	Feb 02 04:14 PM
VRTX	SACHS BRUCE I	Director	Jan 31	Sale	325.01	1,200	390,012	41,210	Feb 02 04:14 PM
VRTX	SACHS BRUCE I	Director	Aug 02	Buy	197.91	15,000	2,968,650	41,210	Aug 04 04:05 PM
VRTX	SACHS BRUCE I	Director	Nov 10	Buy	217.36	15,000	3,260,465	26,210	Nov 12 08:18 AM
VRTX	SACHS BRUCE I	Director	May 07	Option Exercise	70.55	45,000	3,174,525	56,210	May 08 04:24 PM
VRTX	SACHS BRUCE I	Director	May 07	Sale	269.80	45,000	12,140,806	11,210	May 08 04:24 PM
VRTX	SACHS BRUCE I	Director	Jan 31	Option Exercise	53.85	20,000	1,077,000	31,210	Feb 04 04:15 PM
VRTX	SACHS BRUCE I	Director	Jan 31	Sale	227.99	20,000	4,559,830	11,210	Feb 04 04:15 PM
VRTX	SACHS BRUCE I	Director	Dec 06	Option Exercise	34.24	10,000	342,400	23,011	Dec 07 04:06 PM

VRTX	SACHS BRUCE I	Director	Mar 20	Option Exercise	29.89	10,000	298,900	31,210	Mar 24 06:04 PM
VRTX	SACHS BRUCE I	Director	Mar 20	Sale	135.52	10,000	1,355,190	21,210	Mar 24 06:04 PM
VRTX	SACHS BRUCE I	Director	Mar 18	Option Exercise	29.89	10,000	298,900	31,210	Mar 20 04:19 PM
VRTX	SACHS BRUCE I	Director	Mar 18	Sale	130.13	10,000	1,301,300	21,210	Mar 20 04:19 PM
VRTX	SACHS BRUCE I	Director	Jan 20	Option Exercise	28.40	139	3,948	21,349	Jan 22 05:24 PM
VRTX	SACHS BRUCE I	Director	Jan 20	Sale	125.00	139	17,375	21,210	Jan 22 05:24 PM
VRTX	SACHS BRUCE I	Director	Jan 09	Option Exercise	28.40	9,861	280,052	31,071	Jan 13 04:17 PM
VRTX	SACHS BRUCE I	Director	Jan 09	Sale	125.04	9,861	1,233,019	21,210	Jan 13 04:17 PM
VRTX	SACHS BRUCE I	Director	Nov 28	Option Exercise	28.40	10,000	284,000	31,210	Dec 01 05:10 PM
VRTX	SACHS BRUCE I	Director	Nov 28	Sale	120.03	10,000	1,200,300	21,210	Dec 01 05:10 PM
VRTX	SACHS BRUCE I	Director	Nov 06	Option Exercise	29.84	9,900	295,416	31,110	Nov 07 04:25 PM
VRTX	SACHS BRUCE I	Director	Nov 06	Sale	115.21	9,900	1,140,579	21,210	Nov 07 04:25 PM
VRTX	SACHS BRUCE I	Director	Nov 05	Option Exercise	29.84	100	2,984	21,310	Nov 05 05:24 PM
VRTX	SACHS BRUCE I	Director	Nov 03	Option Exercise	34.32	20,000	686,400	41,210	Nov 05 05:24 PM
VRTX	SACHS BRUCE I	Director	Nov 04	Option Exercise	29.84	10,000	298,400	31,210	Nov 05 05:24 PM

VRTX	SACHS BRUCE I	Director	Nov 04	Sale	113.59	10,000	1,135,942	21,210	Nov 05 05:24 PM
VRTX	SACHS BRUCE I	Director	Nov 03	Sale	112.13	20,000	2,242,667	21,210	Nov 05 05:24 PM
VRTX	SACHS BRUCE I	Director	Nov 05	Sale	111.86	100	11,186	21,210	Nov 05 05:24 PM
VRTX	SACHS BRUCE I	Director	Mar 21	Sale	74.59	8,700	648,976	21,210	Mar 25 04:10 PM
VRTX	SACHS BRUCE I	Director	Feb 20	Sale	83.66	8,300	694,349	29,910	Feb 24 04:30 PM
VRTX	SACHS BRUCE I	Director	Jan 22	Sale	84.47	8,300	701,071	38,210	Jan 23 04:16 PM
VRTX	SACHS BRUCE I	Director	Dec 23	Sale	73.02	8,300	606,085	46,510	Dec 26 04:12 PM
VRTX	SACHS BRUCE I	Director	Oct 24	Sale	77.06	8,300	639,586	63,110	Oct 25 04:10 PM
VRTX	SACHS BRUCE I	Director	Sep 25	Sale	74.97	8,300	622,263	71,410	Sep 26 02:09 PM
VRTX	SACHS BRUCE I	Director	Aug 29	Sale	77.19	8,300	640,664	79,710	Sep 03 04:29 PM
VRTX	SACHS BRUCE I	Director	Jul 24	Sale	85.50	8,300	709,621	88,010	Jul 26 04:22 PM
VRTX	SACHS BRUCE I	Director	Jun 21	Sale	75.93	8,300	630,247	96,310	Jun 24 04:40 PM
VRTX	SACHS BRUCE I	Director	May 22	Sale	79.77	8,300	662,116	104,610	May 23 04:14 PM
VRTX	SACHS BRUCE I	Director	May 14	Sale	81.15	60,000	4,869,000	112,910	May 16 04:57 PM
VRTX	SACHS BRUCE I	Director	May 06	Sale	77.22	8,300	640,917	172,910	May 08 04:24 PM
VRTX	SACHS BRUCE I	Director	Jun 03	Sale	55.02	7,500	412,650	181,210	Jun 06 03:33 PM
VRTX	SACHS BRUCE I	Director	May 27	Option Exercise	44.47	7,500	333,525	188,710	Jun 01 03:55 PM
VRTX	SACHS BRUCE I	Director	Jul 02	Option Exercise	14.11	32,500	458,625	201,210	Jul 06 05:19 PM
VRTX	SACHS BRUCE I	Director	Apr 15	Option Exercise	10.05	10,000	100,500	178,710	Apr 16 01:41 PM
VRTX	SACHS BRUCE I	Director	Apr 15	Sale	26.98	10,000	269,800	168,710	Apr 16 01:41 PM
VRTX	SACHS BRUCE I	Director	Feb 15	Buy	18.12	58,710	1,063,695	232,710	Feb 19 11:24 AM
VRTX	SACHS BRUCE I	Director	Feb 14	Buy	18.54	20,000	370,859	174,000	Feb 15 10:28 AM
VRTX	SACHS BRUCE I	Director	Jan 07	Option Exercise	11.58	40,000	463,200	154,000	Jan 08 03:32 PM

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SACHS BRUCE I - Insider Transactions

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