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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| FOLD | MCGLYNN MARGARET G | Director | Mar 05 | Option Exercise | 2.80 | 7,500 | 21,000 | 66,789 | Mar 06 05:21 PM |
| FOLD | MCGLYNN MARGARET G | Director | Mar 04 | Option Exercise | 2.80 | 7,500 | 21,000 | 66,789 | Mar 06 05:21 PM |
| FOLD | MCGLYNN MARGARET G | Director | Mar 04 | Sale | 13.29 | 7,500 | 99,675 | 59,289 | Mar 06 05:21 PM |
| FOLD | MCGLYNN MARGARET G | Director | Mar 05 | Sale | 13.40 | 7,500 | 100,500 | 59,289 | Mar 06 05:21 PM |
| FOLD | MCGLYNN MARGARET G | Director | Jan 13 | Option Exercise | 3.32 | 15,000 | 49,800 | 65,705 | Jan 17 06:03 PM |
| FOLD | MCGLYNN MARGARET G | Director | Jan 13 | Sale | 13.03 | 15,000 | 195,387 | 50,705 | Jan 17 06:03 PM |
| FOLD | MCGLYNN MARGARET G | Director | May 02 | Option Exercise | 4.79 | 15,000 | 71,850 | 53,034 | May 04 07:37 PM |
| FOLD | MCGLYNN MARGARET G | Director | May 02 | Sale | 6.99 | 15,000 | 104,896 | 38,034 | May 04 07:37 PM |
| VRTX | MCGLYNN MARGARET G | Director | Apr 08 | Option Exercise | 127.54 | 5,000 | 637,700 | 6,099 | Apr 12 04:05 PM |
| VRTX | MCGLYNN MARGARET G | Director | Apr 08 | Sale | 280.22 | 5,000 | 1,401,080 | 1,099 | Apr 12 04:05 PM |
| VRTX | MCGLYNN MARGARET G | Director | Mar 31 | Option Exercise | 127.54 | 5,000 | 637,700 | 6,099 | Apr 04 04:05 PM |
| VRTX | MCGLYNN MARGARET G | Director | Mar 31 | Sale | 262.27 | 5,000 | 1,311,346 | 1,099 | Apr 04 04:05 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jan 28 | Option Exercise | 127.54 | 5,000 | 637,700 | 6,099 | Feb 01 04:09 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jan 28 | Sale | 241.79 | 5,000 | 1,208,960 | 1,099 | Feb 01 04:09 PM |
| FOLD | MCGLYNN MARGARET G | Director | May 03 | Option Exercise | 7.51 | 10,000 | 75,100 | 37,919 | May 05 06:01 PM |
| FOLD | MCGLYNN MARGARET G | Director | May 03 | Sale | 10.27 | 10,000 | 102,704 | 27,919 | May 05 06:01 PM |
| FOLD | MCGLYNN MARGARET G | Director | Apr 17 | Option Exercise | 2.81 | 10,000 | 28,100 | 32,064 | Apr 20 04:57 PM |
| FOLD | MCGLYNN MARGARET G | Director | Apr 17 | Sale | 11.00 | 10,000 | 110,000 | 22,064 | Apr 20 04:57 PM |
| FOLD | MCGLYNN MARGARET G | Director | Jan 09 | Option Exercise | 3.32 | 20,000 | 66,400 | 42,064 | Jan 10 05:34 PM |
| FOLD | MCGLYNN MARGARET G | Director | Jan 09 | Sale | 10.00 | 20,000 | 200,000 | 22,064 | Jan 10 05:34 PM |
| VRTX | MCGLYNN MARGARET G | Director | Oct 22 | Option Exercise | 72.14 | 20,000 | 1,442,800 | 24,124 | Oct 24 07:26 PM |
| VRTX | MCGLYNN MARGARET G | Director | Oct 22 | Sale | 190.00 | 20,000 | 3,800,000 | 4,124 | Oct 24 07:26 PM |
| VRTX | MCGLYNN MARGARET G | Director | Aug 13 | Option Exercise | 81.54 | 10,000 | 815,400 | 14,124 | Aug 15 04:11 PM |
| VRTX | MCGLYNN MARGARET G | Director | Aug 13 | Sale | 185.00 | 10,000 | 1,850,000 | 4,124 | Aug 15 04:11 PM |
| FOLD | MCGLYNN MARGARET G | Director | May 16 | Option Exercise | 3.32 | 10,000 | 33,200 | 25,814 | May 18 06:07 PM |
| FOLD | MCGLYNN MARGARET G | Director | May 16 | Sale | 16.00 | 10,000 | 160,000 | 15,814 | May 18 06:07 PM |
| VRTX | MCGLYNN MARGARET G | Director | Mar 02 | Option Exercise | 81.54 | 10,000 | 815,400 | 16,312 | Mar 05 06:13 PM |
| VRTX | MCGLYNN MARGARET G | Director | Mar 02 | Sale | 170.00 | 10,000 | 1,700,000 | 6,312 | Mar 05 06:13 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jan 22 | Option Exercise | 59.55 | 10,000 | 595,500 | 16,217 | Jan 24 05:35 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jan 23 | Option Exercise | 59.55 | 10,000 | 595,500 | 16,217 | Jan 24 05:35 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jan 23 | Sale | 165.00 | 10,000 | 1,650,000 | 6,217 | Jan 24 05:35 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jan 22 | Sale | 160.00 | 10,000 | 1,600,000 | 6,217 | Jan 24 05:35 PM |
| VRTX | MCGLYNN MARGARET G | Director | Nov 18 | Option Exercise | 57.27 | 12,500 | 715,875 | 13,588 | Nov 20 04:09 PM |
| VRTX | MCGLYNN MARGARET G | Director | Nov 18 | Sale | 130.15 | 12,500 | 1,626,875 | 1,088 | Nov 20 04:09 PM |
| FOLD | MCGLYNN MARGARET G | Director | Nov 10 | Buy | 10.27 | 10,000 | 102,657 | 10,000 | Nov 10 04:26 PM |
| VRTX | MCGLYNN MARGARET G | Director | Aug 03 | Option Exercise | 57.27 | 12,500 | 715,875 | 13,588 | Aug 05 04:14 PM |
| VRTX | MCGLYNN MARGARET G | Director | Aug 03 | Sale | 137.28 | 12,500 | 1,716,050 | 1,088 | Aug 05 04:14 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jun 01 | Option Exercise | 55.22 | 12,500 | 690,225 | 13,588 | Jun 03 04:20 PM |
| VRTX | MCGLYNN MARGARET G | Director | Jun 01 | Sale | 127.32 | 12,500 | 1,591,515 | 1,088 | Jun 03 04:20 PM |
| VRTX | MCGLYNN MARGARET G | Director | Apr 06 | Option Exercise | 53.85 | 12,500 | 673,125 | 13,588 | Apr 08 07:25 PM |
| VRTX | MCGLYNN MARGARET G | Director | Apr 06 | Sale | 118.36 | 12,500 | 1,479,523 | 1,088 | Apr 08 07:25 PM |
| VRTX | MCGLYNN MARGARET G | Director | Nov 07 | Buy | 45.50 | 1,000 | 45,500 | 1,000 | Nov 08 04:21 PM |
| MRK | MCGLYNN MARGARET G | President, MV & ID | Mar 03 | Option Exercise | 0.00 | 29,387 | 0 | 54,084 | Mar 05 06:54 PM |
| MRK | MCGLYNN MARGARET G | President, GV & ID | Feb 25 | Option Exercise | 0.00 | 30,541 | 0 | 29,436 | Feb 27 04:44 PM |
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