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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| APLS | Grossi Federico | Chief Medical Officer | Jan 05 | Sale | 48.79 | 2,500 | 121,975 | 94,884 | Jan 09 07:02 PM |
| APLS | Grossi Federico | Chief Medical Officer | Dec 01 | Sale | 49.93 | 2,500 | 124,825 | 97,384 | Dec 02 04:30 PM |
| APLS | Grossi Federico | Chief Medical Officer | Nov 01 | Sale | 60.83 | 2,500 | 152,075 | 99,884 | Nov 03 04:27 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Oct 03 | Sale | 66.69 | 2,500 | 166,725 | 102,384 | Oct 05 05:14 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Sep 01 | Sale | 60.30 | 2,500 | 150,750 | 104,884 | Sep 02 04:22 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Aug 01 | Sale | 55.99 | 2,500 | 139,975 | 107,384 | Aug 02 04:18 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jun 01 | Sale | 41.78 | 2,500 | 104,450 | 109,561 | Jun 02 06:24 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | May 02 | Sale | 43.56 | 2,500 | 108,900 | 112,061 | May 03 07:56 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 15 | Option Exercise | 4.31 | 7,000 | 30,170 | 116,811 | Mar 17 06:19 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 15 | Sale | 39.57 | 375 | 14,839 | 116,436 | Mar 17 06:19 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 01 | Sale | 43.53 | 375 | 16,324 | 109,811 | Mar 02 06:15 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Feb 23 | Option Exercise | 4.31 | 4,100 | 17,671 | 110,186 | Feb 24 04:33 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Feb 15 | Sale | 45.43 | 375 | 17,036 | 106,086 | Feb 16 04:29 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Feb 14 | Option Exercise | 4.31 | 3,600 | 15,516 | 106,461 | Feb 15 04:59 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Feb 01 | Sale | 40.58 | 375 | 15,218 | 103,566 | Feb 02 04:50 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 14 | Option Exercise | 4.31 | 3,400 | 14,654 | 78,915 | Jan 19 08:03 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 14 | Sale | 40.56 | 375 | 15,210 | 78,540 | Jan 19 08:03 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 12 | Option Exercise | 3.92 | 5,161 | 20,230 | 75,515 | Jan 14 04:57 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 03 | Sale | 47.31 | 375 | 17,741 | 70,354 | Jan 04 04:07 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Dec 15 | Sale | 42.88 | 375 | 16,080 | 70,729 | Dec 17 05:10 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Dec 08 | Option Exercise | 3.76 | 7,000 | 26,320 | 71,104 | Dec 09 04:57 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Dec 01 | Sale | 42.40 | 375 | 15,900 | 64,104 | Dec 03 04:00 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Nov 15 | Sale | 43.50 | 625 | 27,188 | 64,479 | Nov 17 05:02 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Nov 01 | Sale | 30.70 | 625 | 19,188 | 64,805 | Nov 02 04:01 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Oct 14 | Sale | 34.57 | 750 | 25,928 | 65,430 | Oct 15 04:02 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Oct 01 | Sale | 33.26 | 750 | 24,945 | 66,180 | Oct 05 04:16 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Sep 28 | Option Exercise | 3.76 | 4,000 | 15,040 | 66,930 | Sep 29 09:48 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Aug 02 | Sale | 63.99 | 250 | 15,998 | 62,930 | Aug 03 04:26 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jul 14 | Sale | 64.68 | 500 | 32,340 | 63,180 | Jul 15 04:56 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jul 08 | Sale | 65.68 | 250 | 16,420 | 63,680 | Jul 09 03:59 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jun 28 | Option Exercise | 3.76 | 9,000 | 33,840 | 63,930 | Jun 29 04:58 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jun 14 | Sale | 61.84 | 500 | 30,920 | 54,930 | Jun 15 04:03 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | May 14 | Sale | 45.39 | 500 | 22,695 | 55,430 | May 18 04:06 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | May 03 | Sale | 50.73 | 600 | 30,438 | 55,614 | May 04 04:11 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Apr 14 | Sale | 42.82 | 500 | 21,410 | 56,214 | Apr 15 05:55 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Apr 01 | Sale | 43.41 | 600 | 26,046 | 56,714 | Apr 05 05:11 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 15 | Sale | 46.77 | 500 | 23,385 | 57,314 | Mar 17 04:14 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 05 | Option Exercise | 3.20 | 5,000 | 16,000 | 62,814 | Mar 08 04:32 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 05 | Sale | 48.62 | 5,000 | 243,075 | 57,814 | Mar 08 04:32 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Mar 01 | Sale | 48.58 | 600 | 29,148 | 57,814 | Mar 03 04:03 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Feb 16 | Sale | 46.00 | 500 | 23,000 | 58,414 | Feb 17 04:12 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Feb 01 | Sale | 44.00 | 600 | 26,400 | 59,602 | Feb 02 04:08 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 25 | Option Exercise | 3.63 | 15,000 | 54,440 | 50,827 | Jan 26 04:25 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 14 | Sale | 51.99 | 4,000 | 207,960 | 35,827 | Jan 15 04:10 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Jan 04 | Sale | 57.24 | 600 | 34,344 | 39,827 | Jan 05 04:21 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Dec 04 | Option Exercise | 3.20 | 7,250 | 23,200 | 40,427 | Dec 08 07:21 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Dec 01 | Sale | 48.25 | 600 | 28,950 | 33,177 | Dec 02 04:30 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Nov 16 | Option Exercise | 3.20 | 5,750 | 18,400 | 33,777 | Nov 17 07:11 PM |
| APLS | Grossi Federico | CHIEF MEDICAL OFFICER | Nov 02 | Sale | 31.09 | 600 | 18,654 | 27,725 | Nov 03 04:01 PM |
| APLS | Grossi Federico | See Remarks | Oct 01 | Sale | 30.22 | 600 | 18,132 | 28,325 | Oct 02 04:14 PM |
| APLS | Grossi Federico | See Remarks | Sep 01 | Sale | 31.58 | 600 | 18,948 | 28,925 | Sep 02 04:36 PM |
| APLS | Grossi Federico | See Remarks | Aug 03 | Sale | 26.28 | 600 | 15,768 | 29,525 | Aug 05 04:37 PM |
| APLS | Grossi Federico | See Remarks | Jul 01 | Sale | 32.43 | 850 | 27,566 | 30,125 | Jul 02 05:48 PM |
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