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| Latest Insider Trading | Top Insider Trading Recent Week | Top 10% Owner Trading Recent Week | Filter
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| Ticker | Owner | Relationship | Date | Transaction | Cost  |
#Shares | Value ($) | #Shares Total | SEC Form 4 |
|---|---|---|---|---|---|---|---|---|---|
| DNLI | Schenkein David P | Director | Nov 11 '24 | Option Exercise | 18.00 | 47,165 | 848,970 | 68,661 | Nov 13 04:18 PM |
| DNLI | Schenkein David P | Director | Nov 11 '24 | Sale | 32.51 | 59,441 | 1,932,665 | 9,220 | Nov 13 04:18 PM |
| DNLI | DAVID SCHENKEIN | Director | Nov 11 '24 | Proposed Sale | 31.35 | 59,441 | 1,863,475 | Nov 12 07:47 AM | |
| AGIO | Schenkein David P | Director | Jun 13 '24 | Option Exercise | 0.00 | 3,388 | 0 | 126,242 | Jun 17 05:29 PM |
| AGIO | Schenkein David P | Director | Feb 27 '24 | Option Exercise | 31.64 | 69,329 | 2,193,570 | 180,325 | Feb 29 04:05 PM |
| AGIO | Schenkein David P | Director | Feb 27 '24 | Sale | 34.67 | 69,329 | 2,403,592 | 122,854 | Feb 29 04:05 PM |
| AGIO | Schenkein David P | Director | Feb 23 '24 | Option Exercise | 31.64 | 47,731 | 1,510,209 | 170,585 | Feb 27 04:04 PM |
| AGIO | Schenkein David P | Director | Feb 26 '24 | Option Exercise | 31.64 | 20,411 | 645,804 | 143,265 | Feb 27 04:04 PM |
| AGIO | Schenkein David P | Director | Feb 26 '24 | Sale | 33.19 | 20,411 | 677,441 | 122,854 | Feb 27 04:04 PM |
| AGIO | Schenkein David P | Director | Feb 23 '24 | Sale | 33.05 | 47,731 | 1,577,510 | 122,854 | Feb 27 04:04 PM |
| AGIO | Schenkein David P | Director | Jun 21 '23 | Option Exercise | 0.00 | 4,975 | 0 | 122,854 | Jun 23 04:34 PM |
| AGIO | Schenkein David P | Director | Apr 03 '23 | Option Exercise | 9.05 | 16,363 | 148,085 | 134,242 | Apr 05 04:03 PM |
| AGIO | Schenkein David P | Director | Apr 03 '23 | Sale | 22.85 | 16,363 | 373,895 | 117,879 | Apr 05 04:03 PM |
| AGIO | Schenkein David P | Director | Mar 27 '23 | Option Exercise | 9.05 | 20,000 | 181,000 | 137,879 | Mar 29 09:30 PM |
| AGIO | Schenkein David P | Director | Mar 27 '23 | Sale | 22.15 | 20,000 | 443,000 | 117,879 | Mar 29 09:30 PM |
| AGIO | Schenkein David P | Director | Mar 13 '23 | Option Exercise | 9.05 | 20,000 | 181,000 | 137,879 | Mar 15 05:11 PM |
| AGIO | Schenkein David P | Director | Mar 13 '23 | Sale | 22.49 | 20,000 | 449,817 | 117,879 | Mar 15 05:11 PM |
| AGIO | Schenkein David P | Director | Feb 27 '23 | Option Exercise | 9.05 | 20,000 | 181,000 | 137,879 | Mar 01 04:06 PM |
| AGIO | Schenkein David P | Director | Feb 27 '23 | Sale | 25.37 | 20,000 | 507,400 | 117,879 | Mar 01 04:06 PM |
| AGIO | Schenkein David P | Director | Feb 13 '23 | Option Exercise | 9.05 | 20,000 | 181,000 | 137,879 | Feb 15 04:03 PM |
| AGIO | Schenkein David P | Director | Feb 13 '23 | Sale | 28.62 | 20,000 | 572,400 | 117,879 | Feb 15 04:03 PM |
| AGIO | Schenkein David P | Director | Jan 30 '23 | Option Exercise | 9.05 | 20,000 | 181,000 | 137,879 | Feb 01 04:04 PM |
| AGIO | Schenkein David P | Director | Jan 30 '23 | Sale | 29.33 | 20,000 | 586,578 | 117,879 | Feb 01 04:04 PM |
| AGIO | Schenkein David P | Director | Jan 17 '23 | Option Exercise | 9.05 | 20,000 | 181,000 | 137,879 | Jan 19 04:03 PM |
| AGIO | Schenkein David P | Director | Jan 17 '23 | Sale | 28.85 | 20,000 | 577,093 | 117,879 | Jan 19 04:03 PM |
| AGIO | Schenkein David P | Director | May 20 '22 | Option Exercise | 0.00 | 1,585 | 0 | 117,879 | May 24 04:11 PM |
| AGIO | Schenkein David P | Director | Feb 22 '22 | Option Exercise | 0.00 | 2,775 | 0 | 117,052 | Feb 23 04:09 PM |
| DNLI | Schenkein David P | Director | Jun 01 '21 | Option Exercise | 0.00 | 3,253 | 0 | 3,253 | Jun 03 08:57 PM |
| AGIO | Schenkein David P | Director | May 28 '21 | Option Exercise | 0.00 | 1,686 | 0 | 114,277 | Jun 02 04:07 PM |
| AGIO | Schenkein David P | Director | Feb 22 '21 | Option Exercise | 0.00 | 2,774 | 0 | 113,412 | Feb 24 04:12 PM |
| AGIO | Schenkein David P | Director | Feb 16 '21 | Option Exercise | 0.00 | 8,125 | 0 | 113,178 | Feb 17 04:12 PM |
| DNLI | Schenkein David P | Director | Dec 21 '20 | Sale | 90.06 | 25,000 | 2,251,555 | 0 | Dec 23 09:52 PM |
| DNLI | Schenkein David P | Director | Dec 21 '20 | Sale | 90.01 | 5,000 | 450,027 | 26,232 | Dec 23 09:52 PM |
| DNLI | Schenkein David P | Director | Nov 12 '20 | Sale | 70.05 | 30,000 | 2,101,590 | 25,000 | Nov 13 05:13 PM |
| DNLI | Schenkein David P | Director | Nov 10 '20 | Sale | 60.03 | 10,000 | 600,310 | 55,000 | Nov 12 04:21 PM |
| DNLI | Schenkein David P | Director | Nov 04 '20 | Sale | 50.18 | 10,000 | 501,830 | 65,000 | Nov 06 05:53 PM |
| AGIO | Schenkein David P | Director | Nov 13 '19 | Buy | 31.00 | 8,064 | 249,984 | 97,567 | Nov 15 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 10 '18 | Option Exercise | 31.64 | 8,730 | 276,217 | 83,849 | Sep 12 04:12 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 05 '18 | Option Exercise | 3.32 | 75,119 | 249,028 | 75,119 | Sep 07 04:22 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 01 '18 | Option Exercise | 0.48 | 13,000 | 6,280 | 13,000 | Jun 05 04:10 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 01 '18 | Sale | 95.35 | 13,000 | 1,239,608 | 0 | Jun 05 04:10 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 30 '18 | Option Exercise | 0.39 | 45,626 | 17,675 | 45,626 | Jun 01 04:08 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 30 '18 | Sale | 90.07 | 45,626 | 4,109,534 | 0 | Jun 01 04:08 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 23 '18 | Option Exercise | 0.30 | 49,374 | 14,936 | 49,374 | May 29 06:17 AM |
| AGIO | Schenkein David P | Chief Executive Officer | May 23 '18 | Sale | 90.40 | 49,374 | 4,463,524 | 0 | May 29 06:17 AM |
| AGIO | Schenkein David P | Chief Executive Officer | May 01 '18 | Option Exercise | 0.30 | 13,000 | 3,932 | 13,000 | May 03 04:07 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 01 '18 | Sale | 83.04 | 13,000 | 1,079,501 | 0 | May 03 04:07 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Apr 02 '18 | Option Exercise | 0.30 | 13,000 | 3,932 | 13,000 | Apr 04 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Apr 02 '18 | Sale | 77.72 | 13,000 | 1,010,357 | 0 | Apr 04 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 01 '18 | Option Exercise | 0.30 | 13,000 | 3,932 | 13,000 | Mar 05 04:32 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 01 '18 | Sale | 81.09 | 13,000 | 1,054,218 | 0 | Mar 05 04:32 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 01 '18 | Option Exercise | 0.30 | 13,000 | 3,932 | 13,000 | Feb 05 04:40 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 01 '18 | Sale | 78.75 | 13,000 | 1,023,756 | 0 | Feb 05 04:40 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 26 '18 | Option Exercise | 0.30 | 23,572 | 7,131 | 23,572 | Jan 30 04:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 26 '18 | Sale | 81.09 | 23,572 | 1,911,494 | 0 | Jan 30 04:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 24 '18 | Option Exercise | 0.30 | 20 | 6 | 20 | Jan 26 04:22 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 24 '18 | Sale | 80.01 | 20 | 1,600 | 0 | Jan 26 04:22 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 23 '18 | Option Exercise | 0.30 | 32,875 | 9,945 | 32,875 | Jan 25 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 24 '18 | Option Exercise | 0.30 | 13,533 | 4,094 | 13,533 | Jan 25 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 24 '18 | Sale | 80.01 | 13,533 | 1,082,775 | 0 | Jan 25 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 23 '18 | Sale | 80.01 | 32,875 | 2,630,329 | 0 | Jan 25 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 16 '18 | Option Exercise | 0.30 | 53,000 | 16,032 | 53,000 | Jan 16 05:16 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 16 '18 | Sale | 73.16 | 53,000 | 3,877,218 | 0 | Jan 16 05:16 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Dec 01 '17 | Option Exercise | 0.30 | 6,000 | 1,815 | 6,000 | Dec 05 04:28 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Dec 01 '17 | Sale | 61.55 | 6,000 | 369,288 | 0 | Dec 05 04:28 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Nov 01 '17 | Option Exercise | 0.30 | 6,000 | 1,815 | 6,000 | Nov 03 04:00 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Nov 01 '17 | Sale | 63.85 | 6,000 | 383,105 | 0 | Nov 03 04:00 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 04 '17 | Option Exercise | 0.30 | 80,000 | 24,200 | 80,000 | Oct 05 06:33 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 04 '17 | Sale | 70.14 | 80,000 | 5,611,200 | 0 | Oct 05 06:33 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 02 '17 | Option Exercise | 0.30 | 6,000 | 1,815 | 6,000 | Oct 04 04:29 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 02 '17 | Sale | 66.76 | 6,000 | 400,560 | 0 | Oct 04 04:29 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 18 '17 | Option Exercise | 0.30 | 35,000 | 10,588 | 35,000 | Sep 20 04:11 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 18 '17 | Sale | 67.12 | 35,000 | 2,349,200 | 0 | Sep 20 04:11 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 01 '17 | Option Exercise | 0.30 | 6,000 | 1,815 | 6,000 | Sep 05 05:22 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 01 '17 | Sale | 62.20 | 6,000 | 373,200 | 0 | Sep 05 05:22 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 01 '17 | Option Exercise | 0.30 | 3,000 | 908 | 3,000 | Aug 03 05:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 02 '17 | Option Exercise | 0.30 | 24,000 | 7,260 | 24,000 | Aug 03 05:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 02 '17 | Sale | 60.55 | 24,000 | 1,453,200 | 0 | Aug 03 05:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 01 '17 | Sale | 55.12 | 3,000 | 165,360 | 0 | Aug 03 05:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jul 03 '17 | Option Exercise | 0.30 | 3,000 | 908 | 3,000 | Jul 06 04:31 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jul 03 '17 | Sale | 51.18 | 3,000 | 153,540 | 0 | Jul 06 04:31 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 07 '17 | Option Exercise | 0.30 | 1,900 | 575 | 1,900 | Jun 08 04:06 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 06 '17 | Option Exercise | 0.30 | 1,100 | 333 | 1,100 | Jun 08 04:06 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 06 '17 | Sale | 50.02 | 1,100 | 55,022 | 0 | Jun 08 04:06 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 07 '17 | Sale | 50.02 | 1,900 | 95,038 | 0 | Jun 08 04:06 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 01 '17 | Option Exercise | 0.30 | 3,000 | 908 | 3,000 | May 02 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 01 '17 | Sale | 50.06 | 3,000 | 150,180 | 0 | May 02 04:03 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Apr 03 '17 | Option Exercise | 0.30 | 3,000 | 908 | 3,000 | Apr 05 04:04 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Apr 03 '17 | Sale | 58.62 | 3,000 | 175,860 | 0 | Apr 05 04:04 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 01 '17 | Option Exercise | 0.30 | 3,000 | 908 | 3,000 | Mar 03 04:36 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 01 '17 | Sale | 50.47 | 3,000 | 151,410 | 0 | Mar 03 04:36 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 16 '17 | Option Exercise | 0.30 | 6,000 | 1,815 | 6,000 | Feb 17 04:36 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 16 '17 | Sale | 50.01 | 6,000 | 300,060 | 0 | Feb 17 04:36 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 07 '16 | Option Exercise | 0.30 | 20,000 | 6,050 | 272,272 | Jan 11 04:22 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 04 '16 | Option Exercise | 0.30 | 10,000 | 3,025 | 242,272 | Jan 05 05:17 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 05 '16 | Option Exercise | 0.30 | 10,000 | 3,025 | 252,272 | Jan 05 05:17 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 27 '15 | Option Exercise | 31.64 | 4,000 | 126,560 | 236,272 | Oct 30 10:52 AM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 27 '15 | Sale | 80.26 | 4,000 | 321,040 | 232,272 | Oct 30 10:52 AM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 03 '15 | Option Exercise | 28.89 | 8,000 | 231,152 | 240,272 | Aug 05 05:11 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 03 '15 | Sale | 110.60 | 8,000 | 884,800 | 232,272 | Aug 05 05:11 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jun 01 '15 | Sale | 120.67 | 13,000 | 1,568,710 | 79,082 | Jun 02 06:19 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 27 '15 | Sale | 120.05 | 8,929 | 1,071,926 | 85,582 | May 28 05:34 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 11 '15 | Sale | 110.01 | 3,107 | 341,801 | 96,794 | May 13 04:39 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 12 '15 | Sale | 110.03 | 2,093 | 230,293 | 94,701 | May 13 04:39 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 07 '15 | Option Exercise | 0.30 | 10,000 | 3,025 | 241,372 | May 11 05:14 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 08 '15 | Sale | 101.32 | 3,900 | 395,148 | 99,901 | May 11 05:14 PM |
| AGIO | Schenkein David P | Chief Executive Officer | May 01 '15 | Sale | 93.63 | 3,900 | 365,157 | 231,372 | May 05 04:54 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Apr 13 '15 | Sale | 100.03 | 3,900 | 390,117 | 101,201 | Apr 15 05:04 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Apr 01 '15 | Sale | 92.54 | 3,900 | 360,906 | 237,872 | Apr 03 05:37 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 05 '15 | Sale | 110.16 | 2,600 | 286,416 | 102,501 | Mar 09 06:41 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 27 '15 | Option Exercise | 0.30 | 25,000 | 7,562 | 248,272 | Mar 03 05:18 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 02 '15 | Sale | 107.05 | 7,800 | 834,990 | 105,101 | Mar 03 05:18 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 11 '15 | Sale | 120.14 | 787 | 94,550 | 107,085 | Feb 13 05:39 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 13 '15 | Sale | 120.31 | 684 | 82,292 | 106,401 | Feb 13 05:39 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Feb 02 '15 | Sale | 114.31 | 10,400 | 1,188,824 | 107,872 | Feb 03 06:34 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jan 02 '15 | Sale | 110.08 | 13,000 | 1,431,040 | 111,772 | Jan 06 05:26 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Dec 01 '14 | Sale | 97.03 | 13,000 | 1,261,390 | 118,272 | Dec 02 06:18 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Nov 03 '14 | Sale | 81.71 | 13,000 | 1,062,230 | 124,772 | Nov 04 06:18 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 01 '14 | Option Exercise | 0.30 | 2,500 | 756 | 255,772 | Oct 03 05:06 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Oct 01 '14 | Sale | 60.07 | 13,000 | 780,910 | 131,272 | Oct 03 05:06 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 02 '14 | Option Exercise | 0.30 | 6,500 | 1,966 | 259,772 | Sep 03 06:17 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Sep 02 '14 | Sale | 46.30 | 13,000 | 601,900 | 167,772 | Sep 03 06:17 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Aug 11 '14 | Sale | 40.17 | 4,530 | 181,970 | 174,272 | Aug 12 06:07 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Jul 01 '14 | Sale | 46.52 | 13,000 | 604,760 | 180,772 | Jul 02 07:12 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 25 '14 | Option Exercise | 0.30 | 25,000 | 7,562 | 266,272 | Mar 27 06:09 PM |
| AGIO | Schenkein David P | Chief Executive Officer | Mar 10 '14 | Option Exercise | 0.30 | 54,000 | 16,335 | 241,272 | Mar 12 06:19 PM |
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