FDA Approval and Strategic Deals Drive Apellis Pharmaceuticals' Stock Higher for the Week

By Venkatesh | August 13, 2025, 1:17 AM

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) is one of the 11 Best Short-Term Stocks to Invest in.

The company’s weekly stock price performance surges following FDA approvals for EMPAVELI, second-quarter 2025 financial results, and capped royalty purchase agreements.

FDA Approval and Strategic Deals Drive Apellis Pharmaceuticals’ Stock Higher for the Week
A biomedical scientist in a lab coat conducting research on biopharmaceutical compounds.

Apellis Pharmaceuticals, Inc. (NASDAQ:APLS), headquartered in Massachusetts, is a global biopharmaceutical enterprise advancing treatments for diseases through complement system modulation. The company has pioneered first-in-class C3-targeting therapies for conditions such as geographic atrophy, rare kidney disorders, and PNH.

On July 28, 2025, Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) received U.S. FDA approval for EMPAVELI for the treatment of patients 12 years and older with C3 glomerulopathy (C3G) and primary immune complex glomerulonephritis (IC-MPGN). With this approval, EMPAVELI becomes the first and only FDA-approved treatment for primary IC-MPGN, adolescent patients with C3G, and post-transplant C3G disease recurrence, thus capturing the unmet demands for the drug.

On July 31, 2025, the company reported its Q2 2025 financial results, showing $178.5 million in total revenues. SYFOVRE U.S. net product revenue reached $150.6 million, with demand growing 6% quarter-over-quarter, maintaining its market leadership in GA.

In the report, the company also highlighted a capped royalty purchase agreement with Sobi, under which it would receive up to $300 million for 90% of ex-U.S. royalties of Aspaveli, including an upfront cash payment of $275 million. With this, Apellis Pharmaceuticals, Inc. (NASDAQ:APLS) focuses on pipeline development and commercial expansion without immediate financial pressure.

Following these developments, the stock price went up 27.70% this week, making a turnaround from its 32.78% yearly loss and drawing interest from traders eyeing biotech bounce-backs.

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