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Vertex Pharmaceuticals (VRTX) Stock Sinks As Market Gains: What You Should Know

By Zacks Equity Research | October 15, 2025, 6:00 PM

Vertex Pharmaceuticals (VRTX) ended the recent trading session at $407.90, demonstrating a -1.05% change from the preceding day's closing price. The stock's change was less than the S&P 500's daily gain of 0.4%. Meanwhile, the Dow experienced a drop of 0.04%, and the technology-dominated Nasdaq saw an increase of 0.66%.

The drugmaker's stock has climbed by 5.33% in the past month, exceeding the Medical sector's gain of 1.8% and the S&P 500's gain of 1.02%.

Market participants will be closely following the financial results of Vertex Pharmaceuticals in its upcoming release. The company plans to announce its earnings on November 3, 2025. The company's earnings per share (EPS) are projected to be $4.53, reflecting a 3.42% increase from the same quarter last year. Alongside, our most recent consensus estimate is anticipating revenue of $3.04 billion, indicating a 9.73% upward movement from the same quarter last year.

For the full year, the Zacks Consensus Estimates are projecting earnings of $17.95 per share and revenue of $11.98 billion, which would represent changes of +4173.81% and +8.76%, respectively, from the prior year.

Investors should also pay attention to any latest changes in analyst estimates for Vertex Pharmaceuticals. These latest adjustments often mirror the shifting dynamics of short-term business patterns. As a result, we can interpret positive estimate revisions as a good sign for the business outlook.

Our research suggests that these changes in estimates have a direct relationship with upcoming stock price performance. To utilize this, we have created the Zacks Rank, a proprietary model that integrates these estimate changes and provides a functional rating system.

The Zacks Rank system, stretching from #1 (Strong Buy) to #5 (Strong Sell), has a noteworthy track record of outperforming, validated by third-party audits, with stocks rated #1 producing an average annual return of +25% since the year 1988. The Zacks Consensus EPS estimate has moved 0.3% lower within the past month. Vertex Pharmaceuticals is holding a Zacks Rank of #3 (Hold) right now.

From a valuation perspective, Vertex Pharmaceuticals is currently exchanging hands at a Forward P/E ratio of 22.97. Its industry sports an average Forward P/E of 19.66, so one might conclude that Vertex Pharmaceuticals is trading at a premium comparatively.

The Medical - Biomedical and Genetics industry is part of the Medical sector. At present, this industry carries a Zacks Industry Rank of 88, placing it within the top 36% of over 250 industries.

The Zacks Industry Rank gauges the strength of our industry groups by measuring the average Zacks Rank of the individual stocks within the groups. Our research shows that the top 50% rated industries outperform the bottom half by a factor of 2 to 1.

To follow VRTX in the coming trading sessions, be sure to utilize Zacks.com.

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Vertex Pharmaceuticals Incorporated (VRTX): Free Stock Analysis Report

This article originally published on Zacks Investment Research (zacks.com).

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