Guardant Health (GH) Q3 Earnings: Taking a Look at Key Metrics Versus Estimates

By Zacks Equity Research | October 29, 2025, 7:30 PM

For the quarter ended September 2025, Guardant Health (GH) reported revenue of $265.2 million, up 38.5% over the same period last year. EPS came in at -$0.39, compared to -$0.45 in the year-ago quarter.

The reported revenue represents a surprise of +13.05% over the Zacks Consensus Estimate of $234.58 million. With the consensus EPS estimate being -$0.48, the EPS surprise was +18.75%.

While investors scrutinize revenue and earnings changes year-over-year and how they compare with Wall Street expectations to determine their next move, some key metrics always offer a more accurate picture of a company's financial health.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how Guardant Health performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:
  • Total tests performed (oncology tests): 74,000 versus 66,824 estimated by three analysts on average.
  • Revenue- Oncology: $184.4 million versus the four-analyst average estimate of $164.62 million.
  • Revenue- Biopharma and data: $54.73 million compared to the $48.38 million average estimate based on four analysts.
  • Revenue- Screening: $24.11 million versus $16.31 million estimated by four analysts on average.
  • Revenue- Licensing and other: $1.95 million versus $2.35 million estimated by three analysts on average.

View all Key Company Metrics for Guardant Health here>>>

Shares of Guardant Health have returned +11.4% over the past month versus the Zacks S&P 500 composite's +3.8% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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This article originally published on Zacks Investment Research (zacks.com).

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