These 2 Medical Stocks Could Beat Earnings: Why They Should Be on Your Radar

By Zacks Equity Research | January 22, 2026, 8:55 AM

Wall Street watches a company's quarterly report closely to understand as much as possible about its recent performance and what to expect going forward. Of course, one figure often stands out among the rest: earnings.

We know earnings results are vital, but how a company performs compared to bottom line expectations can be even more important when it comes to stock prices, especially in the near-term. This means that investors might want to take advantage of these earnings surprises.

Hunting for 'earnings whispers' or companies poised to beat their quarterly earnings estimates is a somewhat common practice. But that doesn't make it easy. One way that has been proven to work is by using the Zacks Earnings ESP tool.

The Zacks Earnings ESP, Explained

The Zacks Earnings ESP, or Expected Surprise Prediction, aims to find earnings surprises by focusing on the most recent analyst revisions. The basic premise is that if an analyst reevaluates their earnings estimate ahead of an earnings release, it means they likely have new information that could possibly be more accurate.

The core of the ESP model is comparing the Most Accurate Estimate to the Zacks Consensus Estimate, where the resulting percentage difference between the two equals the Expected Surprise Prediction. The Zacks Rank is also factored into the ESP metric to better help find companies that appear poised to top their next bottom-line consensus estimate, which will hopefully help lift the stock price.

When we join a positive earnings ESP with a Zacks Rank #3 (Hold) or stronger, stocks posted a positive bottom-line surprise 70% of the time. Plus, this system saw investors produce roughly 28% annual returns on average, according to our 10 year backtest.

Most stocks, about 60%, fall into the #3 (Hold) category, and they are expected to perform in-line with the broader market. Stocks with a #2 (Buy) and #1 (Strong Buy) rating, or the top 15% and top 5% of stocks, respectively, should outperform the market, with Strong Buy stocks outperforming more than any other rank.

Should You Consider Regeneron?

Now that we understand what the ESP is and how beneficial it can be, let's dive into a stock that currently fits the bill. Regeneron (REGN) earns a #1 (Strong Buy) right now and its Most Accurate Estimate sits at $10.72 a share, just eight days from its upcoming earnings release on January 30, 2026.

REGN has an Earnings ESP figure of +1.06%, which, as explained above, is calculated by taking the percentage difference between the $10.72 Most Accurate Estimate and the Zacks Consensus Estimate of $10.6. Regeneron is one of a large database of stocks with positive ESPs. Make sure to utilize our Earnings ESP Filter to uncover the best stocks to buy or sell before they've reported.

REGN is just one of a large group of Medical stocks with a positive ESP figure. Johnson & Johnson (JNJ) is another qualifying stock you may want to consider.

Slated to report earnings on April 21, 2026, Johnson & Johnson holds a #3 (Hold) ranking on the Zacks Rank, and its Most Accurate Estimate is $2.81 a share 89 days from its next quarterly update.

Johnson & Johnson's Earnings ESP figure currently stands at +2.07% after taking the percentage difference between its Most Accurate Estimate and its Zacks Consensus Estimate of $2.75.

REGN and JNJ's positive ESP figures tell us that both stocks have a good chance at beating analyst expectations in their next earnings report.

Find Stocks to Buy or Sell Before They're Reported

Use the Zacks Earnings ESP Filter to turn up stocks with the highest probability of positively, or negatively, surprising to buy or sell before they're reported for profitable earnings season trading. Check it out here >>

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Regeneron Pharmaceuticals, Inc. (REGN): Free Stock Analysis Report
 
Johnson & Johnson (JNJ): Free Stock Analysis Report

This article originally published on Zacks Investment Research (zacks.com).

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