Vertex Pharmaceuticals (VRTX) Exceeds Market Returns: Some Facts to Consider

By Zacks Equity Research | January 22, 2026, 6:00 PM

In the latest trading session, Vertex Pharmaceuticals (VRTX) closed at $467.35, marking a +1.35% move from the previous day. The stock exceeded the S&P 500, which registered a gain of 0.55% for the day. Meanwhile, the Dow experienced a rise of 0.63%, and the technology-dominated Nasdaq saw an increase of 0.91%.

Prior to today's trading, shares of the drugmaker had lost 0.4% lagged the Medical sector's gain of 0.19% and the S&P 500's gain of 0.71%.

Analysts and investors alike will be keeping a close eye on the performance of Vertex Pharmaceuticals in its upcoming earnings disclosure. The company's earnings report is set to go public on February 12, 2026. The company is expected to report EPS of $5.05, up 26.88% from the prior-year quarter. Meanwhile, our latest consensus estimate is calling for revenue of $3.16 billion, up 8.65% from the prior-year quarter.

VRTX's full-year Zacks Consensus Estimates are calling for earnings of $18.4 per share and revenue of $11.97 billion. These results would represent year-over-year changes of +4280.95% and 0%, respectively.

It is also important to note the recent changes to analyst estimates for Vertex Pharmaceuticals. These revisions typically reflect the latest short-term business trends, which can change frequently. Therefore, positive revisions in estimates convey analysts' confidence in the business performance and profit potential.

Our research reveals that these estimate alterations are directly linked with the stock price performance in the near future. To take advantage of this, we've established the Zacks Rank, an exclusive model that considers these estimated changes and delivers an operational rating system.

The Zacks Rank system, which varies between #1 (Strong Buy) and #5 (Strong Sell), carries an impressive track record of exceeding expectations, confirmed by external audits, with stocks at #1 delivering an average annual return of +25% since 1988. Over the past month, the Zacks Consensus EPS estimate remained stagnant. Right now, Vertex Pharmaceuticals possesses a Zacks Rank of #4 (Sell).

Digging into valuation, Vertex Pharmaceuticals currently has a Forward P/E ratio of 23.1. This signifies a premium in comparison to the average Forward P/E of 19.55 for its industry.

The Medical - Biomedical and Genetics industry is part of the Medical sector. At present, this industry carries a Zacks Industry Rank of 88, placing it within the top 36% of over 250 industries.

The Zacks Industry Rank is ordered from best to worst in terms of the average Zacks Rank of the individual companies within each of these sectors. Our research shows that the top 50% rated industries outperform the bottom half by a factor of 2 to 1.

You can find more information on all of these metrics, and much more, on Zacks.com.

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Vertex Pharmaceuticals Incorporated (VRTX): Free Stock Analysis Report

This article originally published on Zacks Investment Research (zacks.com).

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