Jim Cramer Calls Eli Lilly and Company (LLY) a 'Game Changer' After Obesity Pill Trial Success

We recently published a list of Jim Cramer Says Trump’s Fed Chair Tussle Is Like “The Godfather” & Discusses These 10 Stocks. In this article, we are going to take a look at where Eli Lilly and Company (NYSE:LLY) stands against other stocks that Jim Cramer discussed.

In a recent appearance on CNBC’s Squawk on the Street, Jim Cramer discussed whether President Trump could fire the chairman of the Federal Reserve, Jerome Powell. The President is an ardent supporter of low interest rates, and in his recent comments, he asserted that Powell has to reduce rates. However, this particular program wasn’t the first time Cramer discussed the possibility.

In fact, he first raised the possibility in a program aired in late March. We covered Cramer’s remarks as part of our coverage of Jim Cramer Discusses These 10 Stocks & Wonders If Trump Will Try Firing The Fed Chairman. Back then, the CNBC TV host linked the President’s potential action against the Fed chair with the recent dismissals of officials from the Federal Trade Commission.

Cramer commented:

“Look, uh, there is a. . .theme here. You fired two Democrats. In the FTC. No one knows what to do. If he can fire two, if he can fire two from the FTC, he can fire Powell. Now doesn’t matter whether it’s legal or not. I thought Peggy Newton had a great piece today, talking about President Jackson. Now we’re really going back, even before McKinley, which is somehow the North Star for this administration. And I think people are just worried that Powell will be fired cause he’s not cutting rates. And I think that all of that we just heard is irrelevant. What matters that as long as there’s a belief that despite Fed chief Powell saying twice that he’s not going anywhere, as long as there is a belief that President Trump may actually have this . . where he can fire anyone, no one’s safe.”

He added that potential action against Powell might have been priced into the markets as Cramer believed stated: “I’m not saying that he will do this. I am saying that since the FTC. . .look if he took it off the table you would see the futures positive right now.”

Cramer maintained the theme in his latest remarks. When his co-host asked him if it was legally possible for the President to take action against Powell, he commented: “I mean they fired, look, I mean he fired these two FTC people. You’re not supposed to be able to do that.”

Commenting further on the legal aspects, Cramer outlined:

“And there you could say that look Chevron allows me to do it. That Chevron decision. I mean what happens when he comes out and he goes to Truth Social and he says that I’ve decided to run a third term. I mean there’s enough people in the government who would say, yeah, okay.”

As to what happens if the President fires Powell? Well, Cramer thinks “Powell says I’m not fired. I mean, it’ll be funny. You know, I remember Melissa Rivers didn’t want to be fired. In The Apprentice. . . .it’s kind of like The Godfather. Anybody can be fired. . .they can get to Powell.”

Our Methodology

To make our list of the stocks that Jim Cramer talked about, we listed down the stocks he mentioned during CNBC’s Squawk on the Street aired on April 17th.

For these stocks, we also mentioned the number of hedge fund investors. Why are we interested in the stocks that hedge funds pile into? The reason is simple: our research has shown that we can outperform the market by imitating the top stock picks of the best hedge funds. Our quarterly newsletter’s strategy selects 14 small-cap and large-cap stocks every quarter and has returned 373.4% since May 2014, beating its benchmark by 218 percentage points (see more details here).

Eli Lilly and Company (NYSE:LLY)

Number of Hedge Fund Holders In Q4 2024: 115

Eli Lilly and Company (NYSE:LLY) is one of Cramer’s top pharmaceutical stocks. It’s also a stock that he frequently discusses in his morning appearance. While most attention is paid to Eli Lilly and Company (NYSE:LLY)’s weight loss drugs, Cramer has frequently commented that other treatments that Eli Lilly and Company (NYSE:LLY) is developing can also contribute to its already sizable moat. He also believes the firm’s manufacturing investments are a key strength. This time around, Cramer discussed the results of a weight loss pill trial:

[LLY surging after announcing obesity pill was good] “Right, now, David Ricks came on, came on our show and talked about how they’re going to be ready in 2026. I now feel like this could be even faster. What’s most important is what people have to realize is, to get to the number 40 million people taking these drugs which is much more than they have now, you have to have a pill. And the reason is that multiple studies between 76 and 80% of the people, say, I don’t want, I will not take an injection. I must have a pill. So the dropoff of the injection is huge. This will be a giant leap don’t forget they built one of the largest plants, incredibly quickly, in North Carolina. They are ready. This is the game changer for Eli Lilly.”

“No these are the two, the great illnesses, the great epidemics. Now we do have, David, someone who’s head of the HHS, who doesn’t like needles. Ha! Ha!. Pills, partner.”

“Well this study of blood pressure, it is going to show blood pressure not dramatically, but definitely lowered. And so instead of all the different drugs that they use now for blood pressure. They’re gonna use this. And that’s gonna be a study, NYU Langone’s in, everybody’s in the study. And I think that once again it’s gonna be very, very positive for Eli Lilly. There’s a lot of things that are coming out. Don’t forget, that Ken Langone came on my show, and said it is trillion dollar, trillion dollar company. First trillion dolllar non-tech company.”

“I think if you have comorbidity, like if you have diabetes, then you’re gonna get it. If there’s a cardio, where you have a cardio event, you’re gonna get it. It’s gonna be paid. It’ll be paid. But you have to have it in pairing, because I think that they’re just unlikely just to give it to people. Now I will say that, we listened to Gensler yesterday, he said that if worse than. . .you know, deregulation but with no people to actually approve of anything, that’s actually slower than if they actually had cops on the beat so to speak. And it’s interesting because I think the President is so focused on firing people that he’s firing the people who would make it so that you could fast track new things. So it’s almost as if it’s counterintuitive versus what he would like to do. But I find that, you know they wanna fire first and they forget who they’re firing. You wanna fire the people who green light things.”

Overall, LLY ranks 2nd on our list of stocks that Jim Cramer discussed. While we acknowledge the potential of LLY as an investment, our conviction lies in the belief that some AI stocks hold greater promise for delivering higher returns and doing so within a shorter time frame. There is an AI stock that went up since the beginning of 2025, while popular AI stocks lost around 25%. If you are looking for an AI stock that is more promising than LLY but that trades at less than 5 times its earnings, check out our report about this cheapest AI stock.

READ NEXT: 20 Best AI Stocks To Buy Now and 30 Best Stocks to Buy Now According to Billionaires.

Disclosure: None. This article is originally published at Insider Monkey.