Compared to Estimates, OPKO Health (OPK) Q4 Earnings: A Look at Key Metrics

For the quarter ended December 2025, OPKO Health (OPK) reported revenue of $148.5 million, down 19.1% over the same period last year. EPS came in at -$0.04, compared to $0.01 in the year-ago quarter.

The reported revenue represents a surprise of +7.56% over the Zacks Consensus Estimate of $138.06 million. With the consensus EPS estimate being -$0.07, the EPS surprise was +39.39%.

While investors closely watch year-over-year changes in headline numbers -- revenue and earnings -- and how they compare to Wall Street expectations to determine their next course of action, some key metrics always provide a better insight into a company's underlying performance.

As these metrics influence top- and bottom-line performance, comparing them to the year-ago numbers and what analysts estimated helps investors project a stock's price performance more accurately.

Here is how OPKO Health performed in the just reported quarter in terms of the metrics most widely monitored and projected by Wall Street analysts:

• Revenues- Revenue from services: $71.1 million versus the five-analyst average estimate of $72.37 million. The reported number represents a year-over-year change of -31%.
• Revenues- Revenue from transfer of intellectual property and other: $33.7 million compared to the $24.39 million average estimate based on five analysts. The reported number represents a change of -21.8% year over year.
• Revenues- Revenue from products: $43.7 million versus $41.31 million estimated by five analysts on average. Compared to the year-ago quarter, this number represents a +16.8% change.

View all Key Company Metrics for OPKO Health here>>>

Shares of OPKO Health have returned -7.8% over the past month versus the Zacks S&P 500 composite's +0.6% change. The stock currently has a Zacks Rank #3 (Hold), indicating that it could perform in line with the broader market in the near term.

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This article originally published on Zacks Investment Research (zacks.com).

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