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Five Diversified, Ramping DeFi Business Lines Delivered Growth Exceeding Q4 Guidance
Treasury Exceeds 1.93M HYPE, 1.92M KNTQ, & 1.00M HPL Tokens as of March 23(14)
HYPD’s Unique “Triple-Dip” HYPE Deployment Generated ~3x Base Staking Income in Q4
Announces Executed LOI to Monetize the Optejet, With Potential Closing in Q2’26
LAGUNA HILLS, Calif., March 26, 2026 (GLOBE NEWSWIRE) -- Hyperion DeFi, Inc. (NASDAQ: HYPD) (“Hyperion DeFi” or the “Company”), the first U.S. publicly listed DeFi company building on Hyperliquid, today reported results for the fourth quarter and full year ending December 31, 2025.
“Against a backdrop of significant market volatility, we are pleased to report rapid growth in our DeFi operating businesses which exceeded our guidance in the fourth quarter,” said Hyunsu Jung, CEO of Hyperion DeFi. Mr. Jung continued, “Today, we are reporting detail on each business we have built in our first six months under our new DeFi strategy. We continue to make progress on our Company’s corporate transformation as a premier institutional gateway to DeFi innovation, and we expect each business to continue to scale through 2026 and beyond. Hyperion DeFi is building for the future of on-chain finance. This is more than just HYPE.”
Q3’25 and Q4’25 Summary GAAP and Non-GAAP Financial Measures
| (Figures in $) | Q3 2025 | Q4 2025 | |||
| GAAP | Revenue | 302,506 | 496,229 | ||
| Non-GAAP | Adjusted Gross Profit(1) | 439,386 | 820,997 | ||
| GAAP | HYPE Digital Assets | 37,954,590 | 16,233,941 | ||
| Non-GAAP | Gross HYPE Holdings(4) | 77,751,604 | 47,837,901 | ||
| Non-GAAP | Net Asset Value(9) | 74,545,583 | 44,154,737 | ||
| GAAP | Selling, General and Administrative Expense | 2,594,130 | 4,530,542 | ||
| Non-GAAP | Operating Expenses Excluding Stock-Based Compensation(5) | 4,315,016 | 3,007,135 | ||
| GAAP | Net Operating (Income) Expenses | (4,125,685 | ) | 39,958,264 | |
| Non-GAAP | Treasury Gains (Losses)(6) | 11,868,872 | (36,783,228 | ) | |
| GAAP | Total Other Income (Expense), Net | 2,197,391 | (288 | ) | |
| Non-GAAP | Adjusted Other Income (Expense)(7) | (42,240 | ) | 48,717 | |
| GAAP | Net Income (Loss) | 6,625,582 | (39,765,565 | ) | |
| Non-GAAP | Adjusted EBITDA(8) | 7,951,003 | (38,920,649 | ) | |
All figures in this press release are not audited. Throughout this document, totals may not sum due to rounding. Calculations are based on unrounded results.
This press release includes certain non-GAAP financial measures (including on a forward-looking basis) such as Adjusted Gross Profit, Gross HYPE Holdings, Net Asset Value, Operating Expenses Excluding Stock-Based Compensation, Treasury Gains (Losses), Adjusted Other Income (Expense), and Adjusted EBITDA. Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” for reconciliations of non-GAAP financial measures to the most directly comparable GAAP financial measures and important additional information.
| 2025 Actuals & 2026 Guidance (in $ millions) | Q1'25A | Q2'25A | Q3'25A | Q4'25A | FY'25A | FY'26 Guidance | 2026 Guidance vs. 2025 Actual | |||||
| Adjusted Gross Profit(1) | $0.01M | $0.00M | $0.44M | $0.82M | $1.28M | $4M - $6M | ~4x | |||||
| Adjusted Gross Profit(1) By Operating Business Line (In $ Thousands) | Q3'25 | Q4'25 | QoQ Growth | |||||||
| Ecosystem Rewards | - | 285 | >1000% | |||||||
| DeFi Monetization | <1 | 102 | >1000% | |||||||
| Yield Enhancement | 78 | 79 | 2% | |||||||
| Validator Commissions | 21 | 49 | 127% | |||||||
| Staking Yield | 340 | 305 | -10% | |||||||
| Adjusted Gross Profit(1) | 439 | 821 | 87% | |||||||
| Validator Commissions in HYPE(2) | 458 | 1,362 | 197% | |||||||
| Staking Yield in HYPE(2) | 7,437 | 8,713 | 17% | |||||||
| Effective Average HYPE Price In-Period(3) | 45.76 | 35.12 | ||||||||


| HYPE Treasury Over Time | September 30, 2025 | December 31, 2025 | March 23, 2026(14) | |||
| Gross HYPE Tokens(2) | 1.72 M | 1.88 M | 1.93 M | |||
| HYPE Token Price | $45.2 | $25.4 | $38.2 | |||
| Gross HYPE Holdings(4) | $77.8 M | $47.8 M | $73.9 M | |||
| Cash, Cash Equivalents, and USDH | $8.2 M | $6.5 M | $9.2 M | |||
Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” for reconciliations of non-GAAP financial measures to the most directly comparable GAAP financial measures and important additional information.
HYPD Investment Thesis
We believe our Q4’25 results demonstrate that we have transcended the strategy and capabilities of a simple buy-and-hold “DAT” (digital asset treasury company), and instead, we are differentiated as the first U.S. publicly listed DeFi company building on the Hyperliquid blockchain.
Our businesses are designed to simultaneously promote and monetize adoption of the Hyperliquid blockchain. In Q4, our unique ability to “triple-dip” our HYPE tokens across multiple deployment strategies generated ~3x the income would have otherwise generated from staking in isolation. Our “HYPD Triple-Dip” strategy is:
1) Stake our HYPE
2) Deploy the staked HYPE into another business activity – our Validator, Yield Enhancement, or DeFi Monetization, and
3) Position ourselves to receive Ecosystem Rewards
Adjusted Gross Profit(1) in Q3’25 and Q4’25
Adjusted Gross Profit(1), a Non-GAAP Metric, aims to capture all of Hyperion DeFi’s value-add operating business activities beyond simply buying and holding HYPE tokens. In total, Adjusted Gross Profit(1) increased +87% quarter-over-quarter from $439 thousand in Q3’25 to $821 thousand in Q4’25.
Below is a summary of all six of our operating business activities included within Adjusted Gross Profit(1):
| Non-GAAP Income Summary (In $ Thousands) | Q3'25 | Q4'25 |
| Adjusted Gross Profit(1) | 439 | 821 |
| Operating Expenses Excluding Stock-Based Compensation(5) | 4,315 | 3,007 |
| Treasury Gains (Losses)(6) | 11,869 | (36,783) |
| Adjusted Other Income (Expense)(7) | (42) | 49 |
| Adjusted EBITDA(8) | 7,951 | (38,921) |
Please see “Footnotes” and “Non-GAAP Measures of Financial Performance” for reconciliations of non-GAAP financial measures to the most directly comparable GAAP financial measures and important additional information.
Q3’25 and Q4'25 Expense Summary Results
Q3’25 and Q4'25 Treasury Summary
Q3'25 and Q4’25 Net Income (Loss) and Adjusted EBITDA(8)
FY'25 Cash Flows Summary
FY'25 Summary Financial Results
Conference Call & Webcast
Hyperion DeFi, Inc. will host a conference call to discuss fourth quarter and full year 2025 results at 8:00 a.m. Eastern Time on March 26, 2026. A slide presentation that includes supplemental financial information and reconciliations of certain non-GAAP measures to their most directly comparable GAAP measures can be accessed through the Company’s Investor Relations website at https://ir.hyperiondefi.com/events-and-presentations along with information for the conference call. Participants may also submit questions in advance of the call via email to [email protected]. A webcast of the call will be archived and available through April 6, 2026 at 11:59 p.m. Eastern Time on the Company's website.
Presentation
All growth rates represent quarter-over-quarter comparisons, except as otherwise noted. All amounts in tables are presented in U.S. dollars, rounded to the nearest dollar, except as otherwise noted. As a result, certain amounts and rates may not sum or recalculate using the rounded dollar amounts provided. All numbers in this press release are not audited.
About the Hyperliquid Platform and the HYPE Token
Hyperliquid is a next-generation layer one blockchain optimized for high frequency, transparent trading. The blockchain includes fully on-chain perpetual futures and spot order books, with every order, cancel, trade, and liquidation occurring within 70 millisecond block times. It also hosts the HyperEVM, a general-purpose smart contract platform that supports permissionless decentralized financial applications akin to Ethereum.
HYPE is the native token of Hyperliquid. Staked HYPE provides utility for users via reduced trading fees and increased referral bonuses. As of March 2026, more than 41 million HYPE have been autonomously purchased and sequestered by the blockchain with the trading fees generated on the network’s central limit order books.
About Hyperion DeFi, Inc.
Hyperion DeFi, Inc. is the first U.S. publicly listed DeFi company building on Hyperliquid. The Company provides investors with streamlined access to the Hyperliquid ecosystem, one of the fastest growing, highest revenue-generating blockchains in the world. Shareholders benefit from compounding exposure to HYPE, both from its native staking yield and additional revenues generated from its unique on-chain utility.
Hyperion DeFi is also developing its proprietary Optejet User Filled Device that is designed to work with a variety of topical ophthalmic liquids, including artificial tears and lens rewetting products. The Optejet is especially useful in chronic front-of-the-eye diseases due to its ease of use, enhanced safety and tolerability, and potential for superior compliance versus standard eye drops. Together, these benefits may result in higher treatment compliance and better outcomes for patients and providers.
For more information, please visit Hyperiondefi.com or follow @hyperiondefi on X.
Forward Looking Statements; Disclaimer
Except for historical information, all the statements, expectations and assumptions contained in this press release are forward-looking statements. Forward-looking statements include, but are not limited to, statements that express our intentions, beliefs, expectations, strategies, predictions or any other statements, our future activities or other future events or conditions, including the viability of, and risks associated with, our cryptocurrency treasury strategy, the growth and revenue potential of the Hyperliquid ecosystem and the growth prospects of the Company. These statements are based on current expectations, estimates and projections about our business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Therefore, actual outcomes and results may, and in some cases are likely to, differ materially from what is expressed or forecasted in the forward-looking statements due to numerous factors discussed from time to time in documents which we file with the U.S. Securities and Exchange Commission.
Any forward-looking statements speak only as of the date on which they are made, and except as may be required under applicable securities laws, Hyperion DeFi does not undertake any obligation to update any forward-looking statements.
Certain information contained in this press release relates to or is based on studies, publications, surveys and other data obtained from third-party sources and Hyperion DeFi’s own internal estimates and research. While Hyperion DeFi believes these third-party studies, publications, surveys and other data to be reliable as of the date of this press release, it has not independently verified, and makes no representation as to the adequacy, fairness, accuracy or completeness of, any information obtained from third-party sources. In addition, no independent source has evaluated the reasonableness or accuracy of Hyperion DeFi’s internal estimates or research and no reliance should be made on any information or statements made in this press release relating to or based on such internal estimates and research. You should conduct your own investigation and analysis of Hyperion DeFi, its business, prospects, results of operations and financial condition. In furnishing this information, Hyperion DeFi does not undertake any obligation to provide you with access to any additional information (including forward-looking information and any projections contained herein) or to update or correct the information.
Hyperion DeFi, Inc. Investor Contact:
Jason Assad
Hyperion DeFi, Inc.
[email protected]
(678) 570-6791
| Hyperion DeFi, Inc. Balance Sheets | ||||||||
| December 31, | December 31, | |||||||
| 2025 | 2024 | |||||||
| Assets | ||||||||
| Current Assets | ||||||||
| Cash and cash equivalents | $ | 6,443,467 | $ | 2,121,463 | ||||
| Prepaid expenses and other current assets | 802,342 | 645,736 | ||||||
| Total Current Assets | 7,245,809 | 2,767,199 | ||||||
| Digital assets | 16,345,347 | — | ||||||
| Digital assets receivable, net | 6,935,131 | — | ||||||
| Digital intangible assets | 20,591,555 | — | ||||||
| Operating lease right-of-use asset | 415,998 | 718,360 | ||||||
| Other assets | 230,416 | 182,200 | ||||||
| Total Assets | $ | 51,764,256 | $ | 3,667,759 | ||||
| Liabilities and Stockholders’ Equity (Deficit) | ||||||||
| Current Liabilities: | ||||||||
| Accounts payable | $ | 317,900 | $ | 1,954,681 | ||||
| Accrued former licensor obligations | — | 2,245,087 | ||||||
| Accrued expenses and other current liabilities | 1,871,106 | 1,322,674 | ||||||
| Operating lease liabilities - current portion | 512,007 | 575,163 | ||||||
| Notes payable - current portion, net of debt discount of $0 and $527,870 as of December 31, 2025 and December 31, 2024, respectively | — | 5,212,532 | ||||||
| Convertible notes payable - net of debt discount of $0 and $263,930 as of December 31, 2025 and December 31, 2024, respectively | — | 4,736,070 | ||||||
| Total Current Liabilities | 2,701,013 | 16,046,207 | ||||||
| Notes payable - non-current portion, net of debt discount of $543,230 and $0 as of December 31, 2025 and December 31, 2024, respectively | 7,796,136 | — | ||||||
| Operating lease liabilities, non-current portion | 206,600 | 717,504 | ||||||
| Total Liabilities | 10,703,749 | 16,763,711 | ||||||
| Commitments and contingencies (Note 11) | ||||||||
| Stockholders’ Equity (Deficit): | ||||||||
| Preferred stock, $0.0001 par value, 60,000,000 shares authorized; Series A Non-Voting Convertible Preferred Stock, 5,435,898 shares designated, and 5,435,897 and 0 shares issued and outstanding as of December 31, 2025 and December 31, 2024, respectively, with a liquidation preference of $50,795,000 as of December 31, 2025 | 544 | — | ||||||
| Common stock, $0.0001 par value, 600,000,000 shares authorized; 8,762,329 shares issued and 8,680,005 shares outstanding as of December 31, 2025 and 1,506,369 shares issued and outstanding as of December 31, 2024 | 876 | 151 | ||||||
| Additional paid-in capital | 281,937,072 | 182,213,889 | ||||||
| Treasury stock, at cost, 82,324 shares as of December 31, 2025 | (253,558 | ) | — | |||||
| Accumulated deficit | (240,624,427 | ) | (195,309,992 | ) | ||||
| Total Stockholders’ Equity (Deficit) | 41,060,507 | (13,095,952 | ) | |||||
| Total Liabilities and Stockholders’ Equity (Deficit) | $ | 51,764,256 | $ | 3,667,759 | ||||
| Hyperion DeFi, Inc. Statements of Operations | ||||||||
| For the Year Ended | ||||||||
| December 31, | ||||||||
| 2025 | 2024 | |||||||
| Revenue | $ | 813,455 | $ | 57,336 | ||||
| Cost of revenue | (303,290 | ) | (3,927,228 | ) | ||||
| Gross Profit (Loss) | 510,165 | (3,869,892 | ) | |||||
| Operating (Income) Expenses: | ||||||||
| Research and development | 1,910,430 | 14,462,722 | ||||||
| Selling, general and administrative | 17,175,698 | 14,333,114 | ||||||
| Realized gain - digital assets | (8,321,844 | ) | — | |||||
| Unrealized loss - digital assets | 9,030,413 | — | ||||||
| Impairment loss - digital assets | 27,188,768 | — | ||||||
| Impairment loss - other assets | — | 11,207,897 | ||||||
| Gain on covered call option | (157,570 | ) | — | |||||
| Provision for credit losses | 405,331 | — | ||||||
| Reacquisition of license rights | — | 4,864,600 | ||||||
| Net Operating Expenses | 47,231,226 | 44,868,333 | ||||||
| Loss From Operations | (46,721,061 | ) | (48,738,225 | ) | ||||
| Other Income (Expense): | ||||||||
| Other income (expense), net | 389,685 | (90,601 | ) | |||||
| Gain on extinguishment of liabilities | 2,334,711 | — | ||||||
| Change in fair value of equity consideration payable | — | 1,240,800 | ||||||
| Interest expense | (1,557,788 | ) | (2,484,431 | ) | ||||
| Interest income | 240,018 | 254,024 | ||||||
| Total Other Income (Expense), Net | 1,406,626 | (1,080,208 | ) | |||||
| Net Loss | (45,314,435 | ) | (49,818,433 | ) | ||||
| Dividend to preferred stockholders | (1,684,783 | ) | — | |||||
| Net Loss Attributable to Common Stockholders | $ | (46,999,218 | ) | $ | (49,818,433 | ) | ||
| Net Loss per Share - Basic and Diluted | $ | (9.40 | ) | $ | (59.81 | ) | ||
| Shares Outstanding - Basic and Diluted | 5,000,331 | 832,997 | ||||||
| Hyperion DeFi, Inc. Statements of Changes in Stockholders’ (Deficit) Equity | |||||||||||||||||||||||||||||
| For the Years Ended December 31, 2025 and 2024 | |||||||||||||||||||||||||||||
| Total | |||||||||||||||||||||||||||||
| Additional | Stockholders’ | ||||||||||||||||||||||||||||
| Preferred Stock | Common Stock | Paid-In | Treasury Stock | Accumulated | (Deficiency) | ||||||||||||||||||||||||
| Shares | Amount | Shares | Amount | Capital | Shares | Amount | Deficit | Equity | |||||||||||||||||||||
| Balance - January 1, 2024 | — | $ | — | 569,409 | $ | 57 | 154,490,596 | — | $ | — | $ | (145,491,559 | ) | $ | 8,999,094 | ||||||||||||||
| Issuance of common stock in At the Market Program [1] | — | — | 70,381 | 7 | 6,047,362 | — | — | — | 6,047,369 | ||||||||||||||||||||
| Issuance of common stock as consideration for licensing agreement [2] | — | — | 7,668 | 1 | 436,808 | — | — | — | 436,809 | ||||||||||||||||||||
| Issuance of common stock as consideration for reacquisition of licensing agreement [3] | — | — | 28,742 | 3 | 2,322,388 | — | — | — | 2,322,391 | ||||||||||||||||||||
| Issuance of common stock and warrants in offerings [4] | — | — | 653,493 | 66 | 17,011,256 | — | — | — | 17,011,322 | ||||||||||||||||||||
| Exercise of pre-funded stock warrants | — | — | 152,905 | 15 | 1,208 | — | — | — | 1,223 | ||||||||||||||||||||
| Warrant modification and additional warrants - incremental value [5] | — | — | — | — | 2,868,000 | — | — | — | 2,868,000 | ||||||||||||||||||||
| Warrant modification and additional warrants - in issuance costs for offering [6] | — | — | — | — | (2,868,000 | ) | — | — | — | (2,868,000 | ) | ||||||||||||||||||
| Issuance of common stock as consideration for modification of loan agreement | — | — | 23,771 | 2 | 199,998 | — | — | — | 200,000 | ||||||||||||||||||||
| Stock-based compensation: | |||||||||||||||||||||||||||||
| Amortization of stock option awards | — | — | — | — | 1,454,946 | — | — | — | 1,454,946 | ||||||||||||||||||||
| Amortization of restricted stock units | — | — | — | — | 249,327 | — | — | — | 249,327 | ||||||||||||||||||||
| Net loss | — | — | — | — | — | — | — | (49,818,433 | ) | (49,818,433 | ) | ||||||||||||||||||
| Balance - December 31, 2024 | — | — | 1,506,369 | 151 | 182,213,889 | — | — | (195,309,992 | ) | (13,095,952 | ) | ||||||||||||||||||
| Issuance of preferred stock and warrants in private placement [7] | 5,435,897 | 544 | — | — | 49,365,206 | — | — | — | 49,365,750 | ||||||||||||||||||||
| Issuance of common stock in At the Market offering [8] | — | — | 5,607,759 | 561 | 39,357,243 | — | — | — | 39,357,804 | ||||||||||||||||||||
| Issuance of common stock from exercise of warrants [9] | — | — | 502,125 | 50 | 3,892,423 | — | — | — | 3,892,473 | ||||||||||||||||||||
| Induced exercise of stock warrants [10] | — | — | 197,118 | 19 | 922,731 | — | — | — | 922,750 | ||||||||||||||||||||
| Warrants issued in consideration for debt modification | — | — | — | — | 858,270 | — | — | — | 858,270 | ||||||||||||||||||||
| Issuance of common stock from the partial conversion of note payable | — | — | 404,820 | 41 | 640,295 | — | — | — | 640,336 | ||||||||||||||||||||
| Issuance of common stock from the delivery of vested restricted stock units | — | — | 529,297 | 53 | (53 | ) | — | — | — | — | |||||||||||||||||||
| Shares withheld for employee payroll taxes | — | — | — | — | — | 82,324 | (253,558 | ) | — | (253,558 | ) | ||||||||||||||||||
| Reverse stock split settlement of fractional shares | — | — | (41 | ) | — | (160 | ) | — | — | — | (160 | ) | |||||||||||||||||
| Stock-based compensation: | |||||||||||||||||||||||||||||
| Amortization of stock option awards | — | — | — | — | 533,062 | — | — | — | 533,062 | ||||||||||||||||||||
| Amortization of restricted stock units | — | — | — | — | 5,785,548 | — | — | — | 5,785,548 | ||||||||||||||||||||
| Issuance of common stock to vendors in consideration for service provided | — | — | 14,882 | 1 | 53,401 | — | — | — | 53,402 | ||||||||||||||||||||
| Net loss | — | — | — | — | — | — | — | (45,314,435 | ) | (45,314,435 | ) | ||||||||||||||||||
| Preferred stock dividend ($0.59 per preferred share outstanding) | — | — | — | — | (1,684,783 | ) | — | — | — | (1,684,783 | ) | ||||||||||||||||||
| Balance - December 31, 2025 | 5,435,897 | $ | 544 | 8,762,329 | $ | 876 | $ | 281,937,072 | 82,324 | $ | (253,558 | ) | $ | (240,624,427 | ) | $ | 41,060,507 | ||||||||||||
____________________________________
[1] Includes gross proceeds of $6,234,402 less total issuance costs of $187,033.
[2] Shares issued as partial consideration for License Agreement with Formosa Pharmaceuticals Inc.
[3] Shares issued as partial consideration for reversion of License Agreement with Bausch & Lomb Ireland Limited.
[4] Includes gross proceeds of $19,385,015, less total cash issuance costs of $2,373,693.
[5] Offering includes modification of warrants and additional warrants in the July 2024 offering.
[6] Non-cash warrant modification and additional warrants issuance costs related to one of the offerings are shown on a separate line item for clarity.
[7] Includes gross proceeds of $50,000,000 less total issuance costs of $634,250.
[8] Includes gross proceeds of $40,645,265 less total issuance costs of $1,287,461.
[9] Partial exercise of the Armistice warrants.
[10] Includes gross proceeds of $1,039,206 less total issuance costs of $116,456. Also note that incremental value and non-cash warrant modification and additional warrants issuance costs related to the warrant inducement entered into on January 16, 2025 offset to a zero balance. See Note 10 – Stockholders’ Equity (Deficiency).
| Hyperion DeFi, Inc. Statements of Cash Flows | ||||||||
| For the Year Ended | ||||||||
| December 31, | ||||||||
| 2025 | 2024 | |||||||
| Cash Flows From Operating Activities | ||||||||
| Net loss | $ | (45,314,435 | ) | $ | (49,818,433 | ) | ||
| Adjustments to reconcile net loss to net cash and cash equivalents used in operating activities: | ||||||||
| Stock-based compensation | 6,372,012 | 1,704,273 | ||||||
| Change in fair value of equity consideration payable | — | (1,240,800 | ) | |||||
| Depreciation of property and equipment | — | 1,128,449 | ||||||
| Amortization of debt discount | 655,997 | 759,049 | ||||||
| Asset impairments | — | 11,207,897 | ||||||
| Write-down of inventories to net realizable value | — | 3,085,450 | ||||||
| Reacquisition of license rights | — | 2,864,600 | ||||||
| Non-cash lease expense | 302,362 | 528,359 | ||||||
| Gain on extinguishment of liabilities | (2,334,711 | ) | — | |||||
| Non-cash realized gain - digital assets | (3,754,493 | ) | — | |||||
| Unrealized loss - digital assets | 9,030,413 | — | ||||||
| Impairment loss - digital assets | 22,621,417 | — | ||||||
| Staking income | (554,098 | ) | — | |||||
| Non-cash commission paid to co-validators | 26,139 | — | ||||||
| Provision for credit losses | 405,331 | — | ||||||
| Unamortized non-refundable upfront fee on digital asset receivable | 307,278 | — | ||||||
| Interest expense added to note principal | 379,998 | — | ||||||
| Changes in operating assets and liabilities: | ||||||||
| Prepaid expenses and other current assets | (156,587 | ) | 554,020 | |||||
| License fee and expense reimbursement receivables | — | 99,006 | ||||||
| Deferred clinical supply costs | — | 868,328 | ||||||
| Security and equipment deposits | (48,215 | ) | 1,506 | |||||
| Accounts payable | (1,636,781 | ) | 446,596 | |||||
| Accrued compensation | — | (1,514,452 | ) | |||||
| Accrued expenses and other current liabilities | (497,741 | ) | (293,579 | ) | ||||
| Lease liabilities | (574,060 | ) | (501,250 | ) | ||||
| Net Cash and Cash Equivalents Used In Operating Activities | (14,770,174 | ) | (30,120,981 | ) | ||||
| Cash Flows From Investing Activities | ||||||||
| Purchase of property and equipment | — | (161,477 | ) | |||||
| Purchase of productive digital assets | (71,954,039 | ) | — | |||||
| Net Cash and Cash Equivalents Used In Investing Activities | (71,954,039 | ) | (161,477 | ) | ||||
| Cash Flows From Financing Activities | ||||||||
| Proceeds from sale of common stock and warrants in direct offering | — | 19,385,015 | ||||||
| Proceeds from sale of preferred stock and warrants in private placement | 50,000,000 | (2,373,693 | ) | |||||
| Payment of private placement issuance costs | (634,250 | ) | — | |||||
| Proceeds from sale of common stock in At the Market offering | 40,645,265 | 6,234,402 | ||||||
| Payment of issuance costs for At the Market offering | (1,287,461 | ) | (187,033 | ) | ||||
| Proceeds from exercise of stock warrants | 3,892,473 | 1,223 | ||||||
| Proceeds from induced exercise of stock warrants | 1,039,206 | — | ||||||
| Payment of cash issuance costs for induced exercise of stock warrants | (116,456 | ) | — | |||||
| Reverse stock split settlement of fractional shares | (160 | ) | — | |||||
| Repayments of notes payable | (1,463,437 | ) | (5,505,050 | ) | ||||
| Payment of preferred dividend | (892,167 | ) | — | |||||
| Payment of costs in connection with debt extinguishment | (136,796 | ) | — | |||||
| Net Cash and Cash Equivalents Provided By Financing Activities | 91,046,217 | 17,554,864 | ||||||
| Net Increase (Decrease) in Cash and Cash Equivalents | 4,322,004 | (12,727,594 | ) | |||||
| Cash and Cash Equivalents - Beginning of Period | 2,121,463 | 14,849,057 | ||||||
| Cash and Cash Equivalents - End of Period | $ | 6,443,467 | $ | 2,121,463 | ||||
| Hyperion DeFi, Inc. Statements of Cash Flows, continued | ||||||
| For the Year Ended | ||||||
| December 31, | ||||||
| 2025 | 2024 | |||||
| Supplemental Disclosure of Cash Flow Information: | ||||||
| Cash paid during the period for: | ||||||
| Interest | $ | 481,360 | $ | 1,622,479 | ||
| Taxes | $ | — | $ | — | ||
| Supplemental Disclosure of Non-Cash Investing and Financing Activities | ||||||
| Deposits of HYPE into liquid staking activities | $ | 58,753,773 | $ | — | ||
| Redemption of liquid staking tokens for HYPE | $ | 15,675,801 | $ | — | ||
| Transfer of HYPE to digital asset receivable | $ | 9,922,239 | $ | — | ||
| Accrued dividend payable | $ | 792,616 | $ | — | ||
| Purchase of insurance policy financed by note payable | $ | — | $ | 505,050 | ||
| Accrual for intangible asset milestone obligation | $ | — | $ | 2,000,000 | ||
| Reclassification of deferred clinical supply costs to inventories | $ | — | $ | 2,975,652 | ||
| Modification date carrying value of extinguished Avenue Loan | $ | 10,262,280 | $ | — | ||
| Modification date fair value of modified Avenue Loan | $ | 10,172,657 | $ | — | ||
| Warrants issued for debt modification | $ | 858,270 | $ | — | ||
| Warrant modification and additional warrants - incremental value | $ | 1,194,102 | $ | 2,868,000 | ||
| Common stock issued in consideration for equipment received in conjunction with licensing agreement | $ | — | $ | 135,400 | ||
| Conversion of Avenue Loan to common stock | $ | 640,336 | $ | — | ||
| Common stock issued in consideration for licensing agreement | $ | — | $ | 436,809 | ||
| Common stock issued in consideration for reacquisition of licensing agreement | $ | — | $ | 2,322,391 | ||
| Common stock issued as consideration for modification of loan agreement | $ | — | $ | 200,000 | ||
| Interest expense added to note principal | $ | 367,308 | $ | 102,902 | ||
| Issuance of common stock related to vested restricted stock units | $ | 53 | $ | — | ||
| Treasury stock held for employee payroll taxes upon the delivery of restricted stock units | $ | 253,558 | $ | — | ||
Hyperion DeFi Non-GAAP Measures of Financial Performance and Supplemental Disclosures
| Reconciliation of GAAP Revenue to Non-GAAP Adjusted Gross Profit(1) (unaudited) | |||
| For the Three Months Ended | For the Three Months Ended | ||
| September 30, 2025 | December 31, 2025 | ||
| Revenue | $302,506 | $496,229 | |
| Subtract: Cost of Revenue | - | ($303,242) | |
| Add: Accumulated but unrealized staking yield on LSTs(10) | $58,771 | $172,463 | |
| Add: Operating Income from yield enhancement strategies | $78,109 | $79,461 | |
| Add: Realized gains – digital assets from ecosystem rewards | - | $285,450 | |
| Add: Interest Income from DeFi Monetization activity | - | $90,636 | |
| Adjusted Gross Profit(1) | $439,386 | $820,997 | |
Note: See “Footnotes” section for detailed explanations and definitions.
| Q4’25 Reconciliation of GAAP HYPE Digital Assets to Non-GAAP Gross HYPE Holdings(4) (unaudited) | ||||||
| | As of December 31, 2025 | |||||
| Value $ | Token Count | Token Price | ||||
| HYPE - Digital Assets | 16,233,941 | 638,352 | $ 25.43 | |||
| Add: | ||||||
| HYPE digital asset receivable* | 7,647,740 | 300,725 | $25.43 | |||
| HiHYPE at carrying value | 8,437,277 | 398,277 | $21.18 | |||
| kHYPE at carrying value | 11,369,458 | 505,434 | $22.49 | |||
| kmHYPE at carrying value | 649,820 | 28,888 | $22.49 | |||
| Add: Unrealized accretion (dilution) expected upon future LST to HYPE Token reconversion(11) | 3,499,665 | 9,410 | N.M.** | |||
| Gross HYPE Holdings(4) | 47,837,901 | |||||
| Gross HYPE Tokens(2) | 1,881,086 | $ 25.43 | ||||
| Note: See “Footnotes” section for detailed explanations and definitions. | ||||||
| Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of Q3’25 | 4,912,082 | |||||
| In-Period Change in unrealized accretion (dilution) expected upon LST to HYPE vs. Q3’25 | (1,412,417) | |||||
*Presented gross of $405,331 provision for credit losses and $307,278 unamortized nonrefundable upfront fee.
**Throughout this release, N.M. is the abbreviation for “Not Meaningful”.
| Q3’25 Reconciliation of GAAP HYPE Digital Assets to Non-GAAP Gross HYPE Holdings(4) (unaudited) | ||||||
| | As of September 30, 2025 | |||||
| Value $ | Token Count | Token Price | ||||
| HYPE digital assets | 37,954,590 | 839,889 | $45.19 | |||
| Add: HiHYPE at Carrying Value | 34,884,932 | 877,871 | $39.74 | |||
| Add: Unrealized accretion (dilution) expected upon future LST to HYPE Token reconversion(11) | 4,912,082 | 2,788 | N.M. | |||
| Gross HYPE Holdings(4) | 77,751,604 | |||||
| Gross HYPE Tokens(2) | 1,720,549 | $45.19 | ||||
| Note: See “Footnotes” section for detailed explanations and definitions. | ||||||
| Unrealized accretion (dilution) expected upon LST to HYPE reconversion as of June 30, 2025* | 4,912,082 | |||||
*The Company did not hold any LSTs on or prior to June 30, 2025. Therefore, as of September 30, 2025, the in-period change in unrealized accretion (dilution) expected upon LST to HYPE Token Reconversion is the same as the absolute figure.
| Reconciliation of GAAP Selling, General and Administrative expense to Non-GAAP Operating Expense Excluding Stock-Based Compensation(5) (unaudited) | ||||||
| For the Three Months Ended September 30, 2025 | For the Three Months Ended December 31, 2025 | |||||
| Selling, general and administrative expense | $2,594,130 | $4,530,542 | ||||
| Subtract: stock-based compensation expense | $1,347,031 | ($1,712,361) | ||||
| Add: research and development expense | $373,855 | $188,954 | ||||
| Operating Expense Excluding Stock-Based Compensation(5) | $4,315,016 | $3,007,135 | ||||
Note: See “Footnotes” section for detailed explanations and definitions.
| Supplemental Disclosure of Disaggregated Stock-Based Compensation (unaudited) | ||
| ($ in Thousands) | For the Three Months Ended September 30, 2025 | For the Three Months Ended December 31, 2025 |
| Mark-to-market adjustment of vested but undelivered stock-based compensation | (2,140) | - |
| Amortized expensing of unearned executive milestone awards | 210 | 998 |
| All remaining stock-based compensation | 583 | 715 |
| Total Stock-Based Compensation | (1,347) | 1,712 |
| Reconciliation of GAAP Net Operating (Expenses) Income to Non-GAAP Treasury Gains (Losses)(6) (unaudited) | |||||
| For the Three Months Ended September 30, 2025 | For the Three Months Ended December 31, 2025 | ||||
| Net Operating (Expenses) Income | $4,125,685 | ($39,958,264) | |||
| Add Back: | |||||
| Research and development expense | $373,855 | $188,954 | |||
| Selling, general and administrative expense | $2,594,130 | $4,530,542 | |||
| Provision for credit losses | - | $405,331 | |||
| In-Period change in unrealized accretion (dilution) upon LST to HYPE reconversion | $4,912,082 | ($1,412,417) | |||
| Subtract: | |||||
| Accumulated but unrealized staking yield on LSTs(10) | ($58,771) | ($172,463) | |||
| Operating income from airdrops | - | ($285,450) | |||
| Operating income from yield enhancement strategies | ($78,109) | ($79,461) | |||
| Treasury Gains (Losses)(6) | $11,868,872 | ($36,783,228) | |||
Note: See “Footnotes” section for detailed explanations and definitions.
| Reconciliation of GAAP Total Other Income (Expense), Net to Non-GAAP Adjusted Other Income (Expense)(7) (unaudited) | ||||
| For the Three Months Ended September 30, 2025 | For the Three Months Ended December 31, 2025 | |||
| Total Other Income (Expense), Net | $2,197,391 | ($288) | ||
| Add Back: | ||||
| Interest expense | $223,080 | $224,799 | ||
| Reduction in life sciences liabilities(12) | ($2,407,154) | - | ||
| Other non-recurring items(13) | ($55,557) | ($85,158) | ||
| Subtract: Interest income from DeFi Monetization activity | - | ($90,636) | ||
| Adjusted Other Income (Expense)(7) | ($42,240) | $48,717 | ||
Note: See “Footnotes” section for detailed explanations and definitions.
| Reconciliation of GAAP Net Income to Non-GAAP Adjusted EBITDA(8) (unaudited) | ||||
| For the Three Months Ended | For the Three Months Ended | |||
| September 30, 2025 | December 31, 2025 | |||
| Net Income | $6,625,582 | ($39,765,565) | ||
| Add back: | ||||
| Stock-based compensation | ($1,347,031) | $1,712,361 | ||
| Interest expense | $223,080 | $224,799 | ||
| Provision for credit losses | - | $405,331 | ||
| Income Taxes | - | - | ||
| Depreciation and amortization expense* | - | - | ||
| Reductions in life sciences liabilities(12) | ($2,407,154) | - | ||
| Other non-recurring items(13) | ($55,557) | ($85,158) | ||
| Add: In-period change in unrealized accretion (dilution) expected upon LST to HYPE reconversion | $4,912,082 | ($1,412,417) | ||
| Adjusted EBITDA(8) | $7,951,003 | ($38,920,649) | ||
Note: See “Footnotes” section for detailed explanations and definitions.
*Does not include Amortization of Operating Lease.
| Reconciliation of GAAP HYPE digital assets, as adjusted to Gross HYPE Holdings(4), to Non-GAAP Net Asset Value(9) (unaudited) | |||||
| As of | As of | ||||
| September 30, 2025 | December 31, 2025 | ||||
| HYPE digital assets, as adjusted to Gross HYPE Holdings(4) | $77,751,604 | $47,837,901 | |||
| Add: KNTQ digital assets | - | $111,406 | |||
| Add: Current Assets | $9,085,767 | $7,245,809 | |||
| Subtract: Current Liabilities | ($4,037,092) | ($2,701,013) | |||
| Subtract: Notes Payable* | ($8,254,696) | ($8,339,366) | |||
| Net Asset Value(9) | $74,545,583 | $44,154,737 | |||
Note: See “Footnotes” section for detailed explanations and definitions.
*Non-current portion; does not subtract debt discount of $598,691 as of September 30, 2025 or $543,230 as of December 31, 2025.
Footnotes
Photos accompanying this announcement are available at
https://www.globenewswire.com/NewsRoom/AttachmentNg/cba563eb-4952-4229-8844-bd018197e857
https://www.globenewswire.com/NewsRoom/AttachmentNg/d6a0d72c-5503-4a51-85a5-4d201c6f9674

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