| Insider Trading | 
Relationship | 
Date | 
Transaction | 
Cost | 
#Shares | 
Value ($) | 
#Shares Total | 
SEC Form 4 | 
 
| Zanotti Katherine S | Director | Oct 24 '25 | Sale | 65.00 | 12,000 | 780,000 | 60,759 | Oct 27 08:35 PM |  | Zanotti Katherine S | Director | Oct 24 '25 | Proposed Sale | 65.00 | 12,000 | 780,000 |  | Oct 24 11:08 AM |  | Herriott James | SVP, General Counsel & Sec | Oct 09 '25 | Sale | 60.00 | 1,500 | 90,000 | 14,085 | Oct 10 05:27 PM |  | Doyle James Edward | Director | Oct 09 '25 | Sale | 60.00 | 2,000 | 120,000 | 57,962 | Oct 10 05:25 PM |  | Herriott James | Officer | Oct 09 '25 | Proposed Sale | 60.00 | 1,500 | 90,000 |  | Oct 09 11:23 AM |  | Doyle James Edward | Director | Oct 09 '25 | Proposed Sale | 60.00 | 2,000 | 120,000 |  | Oct 09 11:18 AM |  | Doyle James Edward | Director | Aug 13 '25 | Sale | 42.02 | 1,485 | 62,400 | 59,962 | Aug 14 04:30 PM |  | Doyle James Edward | Director | Aug 13 '25 | Proposed Sale | 42.02 | 1,485 | 62,400 |  | Aug 13 10:09 AM |  | ORVILLE JACOB A | EVP, GM, Screening | Aug 05 '25 | Option Exercise | 0.00 | 5,350 | 0 | 30,752 | Aug 07 05:30 PM |  | Baranick Brian | EVP, GM, Precision Oncology | Aug 05 '25 | Option Exercise | 0.00 | 5,350 | 0 | 27,943 | Aug 07 05:30 PM |  | Sebelius Kathleen | Former Director | Jul 16 '25 | Proposed Sale | 53.11 | 8,164 | 433,605 |  | Jul 16 04:22 PM |  | Zanotti Katherine S | Director | Jun 13 '25 | Sale | 53.20 | 3,207 | 170,612 | 72,759 | Jun 16 05:30 PM |  | Zanotti Katherine S | Director | Jun 13 '25 | Proposed Sale | 53.20 | 3,207 | 170,612 |  | Jun 13 09:50 AM |  | Bloomer Aaron | EVP, Chief Financial Officer | Apr 15 '25 | Option Exercise | 0.00 | 24,460 | 0 | 19,340 | Apr 17 04:30 PM |  | Conroy Kevin T | President and CEO | Mar 07 '25 | Option Exercise | 22.38 | 66,723 | 1,493,261 | 1,203,269 | Mar 10 05:00 PM |  | Herriott James | SVP, General Counsel & Sec | Feb 28 '25 | Option Exercise | 0.00 | 4,265 | 0 | 16,339 | Mar 04 04:48 PM |  | Conroy Kevin T | President and CEO | Feb 28 '25 | Option Exercise | 0.00 | 40,310 | 0 | 1,146,965 | Mar 04 04:47 PM |  | Baranick Brian | EVP, GM, Precision Oncology | Feb 28 '25 | Option Exercise | 0.00 | 9,673 | 0 | 25,106 | Mar 04 04:44 PM |  | ORVILLE JACOB A | EVP, GM, Screening | Feb 28 '25 | Option Exercise | 0.00 | 9,673 | 0 | 27,728 | Mar 04 04:40 PM |  | Condella Sarah | EVP, Human Resources | Feb 28 '25 | Option Exercise | 0.00 | 7,738 | 0 | 84,399 | Mar 04 04:37 PM |  | Condella Sarah | EVP, Human Resources | Feb 25 '25 | Option Exercise | 0.00 | 3,954 | 0 | 80,297 | Feb 26 08:00 PM |  | Baranick Brian | EVP, GM, Precision Oncology | Feb 25 '25 | Option Exercise | 0.00 | 3,954 | 0 | 19,841 | Feb 26 08:00 PM |  | Herriott James | SVP, General Counsel & Sec | Feb 25 '25 | Option Exercise | 0.00 | 1,647 | 0 | 13,738 | Feb 26 08:00 PM |  | ORVILLE JACOB A | EVP, GM, Screening | Feb 25 '25 | Option Exercise | 0.00 | 3,954 | 0 | 22,136 | Feb 26 08:00 PM |  | Conroy Kevin T | President and CEO | Feb 25 '25 | Option Exercise | 0.00 | 13,180 | 0 | 1,121,378 | Feb 26 08:00 PM |  | Conroy Kevin T | President and CEO | Feb 19 '25 | Option Exercise | 0.00 | 10,374 | 0 | 1,084,565 | Feb 21 04:30 PM |  | COWARD D SCOTT | Director | Feb 19 '25 | Option Exercise | 0.00 | 2,248 | 0 | 52,831 | Feb 21 04:30 PM |  | ORVILLE JACOB A | EVP, GM, Screening | Feb 19 '25 | Option Exercise | 0.00 | 2,248 | 0 | 16,688 | Feb 21 04:30 PM |  | Baranick Brian | EVP, GM, Precision Oncology | Feb 19 '25 | Option Exercise | 0.00 | 1,729 | 0 | 14,487 | Feb 21 04:30 PM |  | Condella Sarah | EVP, Human Resources | Feb 19 '25 | Option Exercise | 0.00 | 2,248 | 0 | 74,859 | Feb 21 04:30 PM |  | Herriott James | SVP, General Counsel & Sec | Feb 19 '25 | Option Exercise | 0.00 | 865 | 0 | 10,731 | Feb 21 04:30 PM |  | Conroy Kevin T | President and CEO | Nov 13 '24 | Buy | 51.35 | 19,500 | 1,001,325 | 1,074,191 | Nov 13 12:56 PM |   
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