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AC Immune SA
Index- P/E- EPS (ttm)-0.95 Insider Own46.99% Shs Outstand71.93M Perf Week2.93%
Market Cap559.65M Forward P/E- EPS next Y-0.56 Insider Trans0.00% Shs Float34.30M Perf Month29.26%
Income-68.40M PEG- EPS next Q-0.27 Inst Own28.60% Short Float3.39% Perf Quarter38.78%
Sales17.60M P/S31.80 EPS this Y177.60% Inst Trans-2.77% Short Ratio1.14 Perf Half Y3.62%
Book/sh3.59 P/B2.15 EPS next Y38.50% ROA-22.10% Target Price13.25 Perf Year10.74%
Cash/sh3.77 P/C2.05 EPS next 5Y- ROE-24.20% 52W Range4.07 - 13.00 Perf YTD49.52%
Dividend- P/FCF- EPS past 5Y26.30% ROI16.20% 52W High-42.54% Beta0.82
Dividend %- Quick Ratio18.10 Sales past 5Y29.70% Gross Margin- 52W Low83.54% ATR0.82
Employees115 Current Ratio18.10 Sales Q/Q-96.70% Oper. Margin- RSI (14)51.57 Volatility6.65% 12.66%
OptionableYes Debt/Eq0.01 EPS Q/Q-204.80% Profit Margin- Rel Volume0.33 Prev Close7.73
ShortableYes LT Debt/Eq0.01 Earnings- Payout- Avg Volume1.02M Price7.47
Recom1.70 SMA20-2.70% SMA5014.04% SMA20016.16% Volume160,550 Change-3.36%
Feb-01-19Downgrade UBS Buy → Neutral
Jan-04-19Initiated UBS Buy
Apr-05-18Initiated H.C. Wainwright Buy $18
Mar-23-18Downgrade Credit Suisse Outperform → Neutral
Oct-18-16Initiated Leerink Partners Outperform
Oct-18-16Initiated Jefferies Buy $25
Oct-18-16Initiated Credit Suisse Outperform $18
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AC Immune SA, a clinical stage biopharmaceutical company, discovers, designs, and develops therapeutic and diagnostic products for the prevention, diagnosis, and treatment of neurodegenerative diseases associated with protein misfolding. Its SupraAntigen and Morphomer platforms are designed to generate vaccines, antibodies, and small molecules, which selectively interact with misfolded proteins that are common in a range of neurodegenerative diseases. The company's lead product candidate is crenezumab, a humanized, monoclonal, and conformation-specific anti-Abeta antibody, which is in Phase II clinical prevention trial for the treatment of Alzheimer's disease (AD). It is also developing ACI-24, an anti-Abeta vaccine candidate that is in Phase II clinical study for AD, as well as is in Phase Ib clinical study for Down syndrome; ACI-35, an anti-Tau vaccine candidate that has completed Phase Ib clinical study; RG6100, an anti-Tau antibody candidate, which is in Phase II clinical study for AD patients; and Tau-PET imaging tracer that has completed Phase I clinical study. In addition, the company is researching and developing Tau Morphomer aggregation inhibitor small molecules for AD. Further, it has discovery and pre-clinical stage molecules targeting neurodegenerative diseases, as well as diagnostics targeting Tau, alpha-synuclein, and TDP-43 aggregates. The company has license agreements and collaborations with Genentech, Inc.; Biogen International GmbH; Janssen Pharmaceuticals, Inc.; Life Molecular Imaging SA; Eli Lilly and Company; Essex Bio-Technology Limited; and WuXi Biologics. It also has a research collaboration with University of Pennsylvania to focus on pathogenic protein TDP-43 in neurodegenerative diseases. AC Immune SA was founded in 2003 and is headquartered in Lausanne, Switzerland.