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Pfizer is Locking in New Growth Through a New Acquisition

By Gabriel Osorio-Mazilli | September 26, 2025, 4:33 PM

Pfizer Building

In the United States' healthcare sector, a new growth theme is emerging that nearly all companies want to capitalize on. Like artificial intelligence for technology stocks, weight loss drug manufacturing and distribution businesses are all the hype for this new growth wave taking over the industry.

That said, there are two ways for businesses to capitalize on this opportunity and deliver value for shareholders.

The first is to develop proprietary weight loss drugs, but by the time they are set for regulatory trials, it might be too late, as other companies in the industry could have already achieved a breakthrough.

The second is by acquisition, though only the biggest and most powerful companies can go through this process. They can "flex" their financial muscle by combining their businesses with smaller ones and hyperscaling them to their full potential.

This is where a $136.9 billion company like Pfizer Inc. (NYSE: PFE) has made headlines, opting for option number two this time. A recent press release surprised investors when they learned that Pfizer is looking to close a transaction worth between $4.9 billion and $7.3 billion, acquiring Metsera Inc. (NASDAQ: MTSR).

This acquisition sent Metsera stock higher by 57.6% in a single week. However, the real upside is likely to be realized when it merges with Pfizer next time around.

How Pfizer Stock Will Be Affected

First and foremost, Pfizer will now be exposed to the high-growth weight loss products market. Injecting Metsera with Pfizer's expertise and financial prowess increases the odds of a successful product launch, which would expand Pfizer's business beyond vaccines and traditional pharma products, decreasing financial volatility.

More than just adding a new product line, the addition is essentially a "shoe-in" for Pfizer, as it already has a manufacturing and commercial infrastructure operating at average capacity. Therefore, the added task of weight loss drug manufacturing would be a small move in the needle in terms of additional costs.

In other words, this new department would carry a higher-than-average margin level for Pfizer's entire business, which would trickle down into earnings per share (EPS) expansion and stock valuations.

However bullish this may seem, Pfizer still trades at only 80% of its 52-week high, where investors can start stepping in ahead of time.

Locking in the stock at this price enables new shareholders to be exposed to the positive effects this new business can have on Pfizer before it becomes obvious to the rest of the market. In this realization theme, there is one major catalyst that investors can now look forward to, one that will come directly from Wall Street.

Where Pfizer Could Be Headed Next

Even without factoring in the potential benefits of the Metsera acquisition, the current Wall Street consensus price target is set at $28.12 per share, accompanied by a Hold rating. This view still implies a net upside potential of 16.8% from today's prices, so that's a starting point investors can work off from.

However, in the acquisition announcement, Pfizer management mentioned that they will update their financial guidance and outlook during the fourth-quarter 2025 earnings release. To retail investors, Wall Street analysts are now racing to be the first to release their new price targets on Pfizer ahead of the announcement.

Given the bullish future prospects of combining these two businesses, these new ratings are expected to be significantly above the consensus. While this future catalyst remains speculative (though highly likely), investors also have a few more current indicators that could connect the dots for this current development within the company.

Over the past month, Pfizer's short interest declined by 9.1% despite a lack of bullish price action. Perhaps the view was that, as the weight loss market begins to heat up, Pfizer only needed a small push toward a decision to make such an acquisition, enough of an idea to scare off some short sellers despite no reason to do so in the chart itself.

More than just short sellers bailing, some institutional buyers had also been conveniently buying Pfizer ahead of the announcement.

One is Canada Life Assurance Co., which recently increased its Pfizer stock holdings by 19.6% as of August 2025. While the timing was a month off from the announcement, the buildup to a new $207.7 million position cannot be ignored.

Whether the dozens of capable analysts working for a firm like Canada Life Assurance thought of this scenario or not is up for debate, but what isn't is that there is enough institutional interest now, even before the financial benefits from this acquisition become clear. Then there's the analyst boost catalyst still in play, waiting for investors to take advantage of it.

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The article "Pfizer is Locking in New Growth Through a New Acquisition " first appeared on MarketBeat.

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