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Last Close
Feb 12  •  10:47AM ET
46.58
Dollar change
-0.64
Percentage change
-1.36
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IndexRUT P/E- EPS (ttm)-2.25 Insider Own45.74% Shs Outstand48.08M Perf Week5.98%
Market Cap2.24B Forward P/E- EPS next Y-3.14 Insider Trans-1.12% Shs Float26.11M Perf Month12.54%
Enterprise Value1.88B PEG- EPS next Q-0.71 Inst Own44.33% Short Float10.50% Perf Quarter44.39%
Income-101.46M P/S- EPS this Y-350.27% Inst Trans11.85% Short Ratio5.93 Perf Half Y242.50%
Sales0.00M P/B5.90 EPS next Y-0.33% ROA-28.15% Short Interest2.74M Perf YTD12.43%
Book/sh7.89 P/C5.84 EPS next 5Y- ROE-36.13% 52W High49.25 -5.42% Perf Year288.81%
Cash/sh7.98 P/FCF- EPS past 3/5Y- - ROIC-25.44% 52W Low6.71 594.19% Perf 3Y-
Dividend Est.- EV/EBITDA- Sales past 3/5Y- - Gross Margin- Volatility10.09% 7.97% Perf 5Y-
Dividend TTM- EV/Sales- EPS Y/Y TTM- Oper. Margin- ATR (14)3.15 Perf 10Y-
Dividend Ex-Date- Quick Ratio17.70 Sales Y/Y TTM- Profit Margin- RSI (14)55.97 Recom1.00
Dividend Gr. 3/5Y- - Current Ratio17.70 EPS Q/Q-1029.60% SMA203.23% Beta4.50 Target Price51.12
Payout- Debt/Eq0.06 Sales Q/Q-100.00% SMA5010.11% Rel Volume2.22 Prev Close47.22
Employees125 LT Debt/Eq0.05 EarningsNov 06 AMC SMA20085.50% Avg Volume462.61K Price46.58
IPOJan 31, 2025 Option/ShortYes / Yes EPS/Sales Surpr.6.81% - Trades Volume243,891 Change-1.36%
Date Action Analyst Rating Change Price Target Change
Dec-04-25Initiated Wells Fargo Overweight $55
Nov-14-25Initiated Raymond James Outperform
Sep-02-25Initiated BTIG Research Buy $30
Jul-23-25Initiated H.C. Wainwright Buy $34
Jul-08-25Initiated Wedbush Outperform $17
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Maze Therapeutics, Inc. is a clinical-stage biopharmaceutical company, which engages in harnessing the power of human genetics to develop novel, small molecule precision medicines for patients living with renal, cardiovascular, and related metabolic, or CVRM diseases. Its pipeline includes the Compass platform, which allows it to identify and characterize genetic variants in disease and then link those variants to the biological pathways that drive disease in specific patient groups through a process to refer a variant functionalization. The company was founded by Mark Daly, Aaron D. Gitler, Stephen Elledge, Sekar Kathiresan, and Jonathan S. Weissman on August 29, 2017 and is headquartered in San Francisco, CA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Bernstein HaroldPresident, R&D & CMOFeb 02 '26Option Exercise10.4215,000156,30015,000Feb 04 04:25 PM
Bernstein HaroldPresident, R&D & CMOFeb 02 '26Sale46.0215,000690,3340Feb 04 04:25 PM
Bachrodt AmySVP, FinanceFeb 02 '26Option Exercise10.425,00052,10017,965Feb 04 04:23 PM
Bachrodt AmySVP, FinanceFeb 02 '26Sale46.045,000230,21912,965Feb 04 04:23 PM
Dandekar AtulCSBOJan 29 '26Option Exercise10.427,50078,15018,003Feb 02 04:21 PM
Dandekar AtulCSBOJan 29 '26Sale44.277,500331,99010,503Feb 02 04:21 PM
Bachrodt AmySVP, FinanceJan 22 '26Option Exercise10.425,00052,10017,965Jan 26 04:10 PM
Bachrodt AmySVP, FinanceJan 22 '26Sale45.525,000227,61212,965Jan 26 04:10 PM
SEKAR KATHIRESANFormer DirectorJan 16 '26Proposed Sale40.6729,7721,210,937Jan 16 04:28 PM
Bernstein HaroldPresident, R&D & CMOJan 07 '26Option Exercise10.4225,156262,12625,156Jan 09 04:51 PM
Bernstein HaroldPresident, R&D & CMOJan 07 '26Sale40.2025,1561,011,2990Jan 09 04:51 PM
Sohn Catherine A.DirectorJan 07 '26Option Exercise10.4226,920280,50626,920Jan 08 04:30 PM
Sohn Catherine A.DirectorJan 06 '26Option Exercise10.422,49325,9772,493Jan 08 04:30 PM
Sohn Catherine A.DirectorJan 07 '26Sale39.1126,9201,052,7850Jan 08 04:30 PM
Sohn Catherine A.DirectorJan 06 '26Sale38.622,49396,2700Jan 08 04:30 PM
CATHERINE SOHNDirectorJan 07 '26Proposed Sale39.1126,9201,052,785Jan 07 04:00 PM
CATHERINE SOHNDirectorJan 06 '26Proposed Sale38.622,49396,270Jan 06 04:36 PM
Bernstein HaroldPresident, R&D & CMOJan 02 '26Option Exercise10.424,43246,1814,432Jan 06 04:31 PM
Bernstein HaroldPresident, R&D & CMOJan 05 '26Option Exercise10.424124,293412Jan 06 04:31 PM
Bernstein HaroldPresident, R&D & CMOJan 02 '26Sale40.434,432179,1880Jan 06 04:31 PM
Bernstein HaroldPresident, R&D & CMOJan 05 '26Sale40.0041216,4800Jan 06 04:31 PM
Bachrodt AmySVP, FinanceJan 02 '26Option Exercise10.425,00052,10017,965Jan 06 04:30 PM
Bachrodt AmySVP, FinanceJan 02 '26Sale39.155,000195,75412,965Jan 06 04:30 PM
Dandekar AtulCSBODec 29 '25Option Exercise10.4272,400754,40882,903Dec 31 04:24 PM
Dandekar AtulCSBODec 30 '25Option Exercise10.421001,04210,603Dec 31 04:24 PM
Dandekar AtulCSBODec 29 '25Sale40.5672,4002,936,76310,503Dec 31 04:24 PM
Dandekar AtulCSBODec 30 '25Sale40.361004,03610,503Dec 31 04:24 PM
Bernstein HaroldPresident, R&D & CMODec 29 '25Option Exercise10.4245,000468,90045,000Dec 31 04:22 PM
Bernstein HaroldPresident, R&D & CMODec 29 '25Sale40.5645,0001,825,3550Dec 31 04:22 PM
Bachrodt AmySVP, FinanceDec 29 '25Option Exercise10.4210,000104,20022,965Dec 31 04:20 PM
Bachrodt AmySVP, FinanceDec 30 '25Option Exercise10.425,00052,10017,965Dec 31 04:20 PM
Bachrodt AmySVP, FinanceDec 29 '25Sale40.5810,000405,76612,965Dec 31 04:20 PM
Bachrodt AmySVP, FinanceDec 30 '25Sale40.085,000200,40712,965Dec 31 04:20 PM
HAROLD BERNSTEINOfficerDec 29 '25Proposed Sale42.10105,0004,420,500Dec 29 04:28 PM
ATUL P DANDEKAROfficerDec 29 '25Proposed Sale42.1087,5003,683,750Dec 29 04:25 PM
SEKAR KATHIRESANFormer Board MemberDec 04 '25Proposed Sale42.5410,000425,423Dec 04 04:08 PM
SEKAR KATHIRESANFormer Board MemberNov 21 '25Proposed Sale35.8027,500984,588Nov 21 04:09 PM
SCHELLER RICHARD HDirectorSep 15 '25Sale22.3720,744464,0350Sep 16 04:26 PM
RICHARD SCHELLERDirectorSep 15 '25Proposed Sale22.3720,744464,035Sep 15 04:07 PM
Last Close
Feb 12  •  10:47AM ET
1.93
Dollar change
+0.01
Percentage change
0.52
%
ALEC Alector Inc daily Stock Chart
IndexRUT P/E- EPS (ttm)-1.07 Insider Own30.00% Shs Outstand107.45M Perf Week6.04%
Market Cap210.66M Forward P/E- EPS next Y-0.99 Insider Trans-0.93% Shs Float76.40M Perf Month0.52%
Enterprise Value-42.57M PEG- EPS next Q-0.38 Inst Own63.42% Short Float8.55% Perf Quarter41.91%
Income-107.74M P/S3.05 EPS this Y-16.49% Inst Trans-13.59% Short Ratio5.05 Perf Half Y-11.47%
Sales69.05M P/B3.59 EPS next Y30.77% ROA-25.31% Short Interest6.53M Perf YTD23.72%
Book/sh0.54 P/C0.72 EPS next 5Y1.36% ROE-121.98% 52W High3.40 -43.23% Perf Year17.68%
Cash/sh2.67 P/FCF- EPS past 3/5Y-39.73% 6.31% ROIC-124.39% 52W Low0.87 121.84% Perf 3Y-79.53%
Dividend Est.- EV/EBITDA- Sales past 3/5Y-21.40% 36.50% Gross Margin86.27% Volatility6.50% 6.25% Perf 5Y-90.83%
Dividend TTM- EV/Sales-0.62 EPS Y/Y TTM37.36% Oper. Margin-172.76% ATR (14)0.11 Perf 10Y-
Dividend Ex-Date- Quick Ratio3.76 Sales Y/Y TTM12.26% Profit Margin-156.03% RSI (14)57.64 Recom3.12
Dividend Gr. 3/5Y- - Current Ratio3.76 EPS Q/Q21.95% SMA200.92% Beta0.63 Target Price2.10
Payout- Debt/Eq0.66 Sales Q/Q-78.75% SMA5016.49% Rel Volume0.37 Prev Close1.92
Employees238 LT Debt/Eq0.50 EarningsNov 06 AMC SMA2005.38% Avg Volume1.29M Price1.93
IPOFeb 07, 2019 Option/ShortYes / Yes EPS/Sales Surpr.16.56% -6.52% Trades Volume114,385 Change0.52%
Date Action Analyst Rating Change Price Target Change
Oct-22-25Downgrade William Blair Outperform → Mkt Perform
Oct-22-25Downgrade TD Cowen Buy → Hold
Oct-22-25Downgrade Mizuho Outperform → Neutral $1.50
Oct-22-25Downgrade Cantor Fitzgerald Overweight → Neutral
Oct-22-25Downgrade BTIG Research Buy → Neutral
Jul-28-25Upgrade Mizuho Neutral → Outperform $3.50
Dec-17-24Downgrade Mizuho Outperform → Neutral $9 → $2.50
Dec-16-24Downgrade Stifel Buy → Hold $4
Dec-04-24Downgrade BofA Securities Neutral → Underperform $9 → $1
Nov-29-24Reiterated H.C. Wainwright Buy $35 → $7
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Alector, Inc. operates as a clinical-stage biopharmaceutical company, which engages in pioneering of immuno-neurology. It develops portfolio of innate immune system programs, designed to functionally repair genetic mutations and enable the rejuvenated immune cells to counteract emerging brain pathologies. Its treatment targets immune dysfunction as a root cause of multiple pathologies that are drivers of degenerative brain disorders. The company was founded by Asa Abeliovich, Errik B. Anderson, Tillman U. Gerngross, and Arnon Rosenthal in May 2013 and is headquartered in South San Francisco, CA.
Insider Trading Relationship Date Transaction Cost #Shares Value ($) #Shares Total SEC Form 4
Wong-Sarad GracePrincipal Accounting OfficerDec 05 '25Sale1.214,7535,751122,982Dec 08 06:03 PM
GRACE WONG-SARADOfficerDec 05 '25Proposed Sale1.214,7535,751Dec 05 04:09 PM
Wong-Sarad GracePrincipal Accounting OfficerDec 03 '25Sale1.128,0569,019127,735Dec 03 09:07 PM
Rosenthal ArnonChief Executive OfficerDec 03 '25Sale1.12104,347116,8272,420,040Dec 03 09:06 PM
Kenkare-Mitra SaraPresident and Head of R&DDec 03 '25Sale1.1241,68746,673501,652Dec 03 09:05 PM
Berkley Neil LindsayChief Bus Ofcr & Interim CFODec 03 '25Sale1.1237,26141,717374,309Dec 03 09:04 PM
Arnon RosenthalOfficerDec 01 '25Proposed Sale1.2392,427113,685Dec 01 07:53 PM
Neil L. BerkleyOfficerDec 01 '25Proposed Sale1.2332,99240,580Dec 01 07:50 PM
Grace Wong-SaradOfficerDec 01 '25Proposed Sale1.237,0858,715Dec 01 07:49 PM
Sara Kenkare-MitraOfficerDec 01 '25Proposed Sale1.2336,91445,404Dec 01 07:48 PM
Wong-Sarad GracePrincipal Accounting OfficerSep 02 '25Sale2.505,91014,756103,448Sep 04 04:33 PM
Berkley Neil LindsayPrincipal Financial OfficerSep 02 '25Sale2.5015,84239,554346,570Sep 04 04:32 PM
Kenkare-Mitra SaraPresident and Head of R&DSep 02 '25Sale2.5023,63859,019543,339Sep 04 04:29 PM
Rosenthal ArnonChief Executive OfficerSep 02 '25Sale2.5051,562128,7402,350,220Sep 04 04:27 PM
Neil L. BerkleyOfficerSep 02 '25Proposed Sale2.3515,42636,251Aug 29 06:25 PM
Arnon RosenthalOfficerSep 02 '25Proposed Sale2.3550,242118,069Aug 29 06:23 PM
Grace Wong-SaradOfficerSep 02 '25Proposed Sale2.355,71713,435Aug 29 06:20 PM
Sara Kenkare-MitraOfficerSep 02 '25Proposed Sale2.3523,01954,095Aug 29 06:17 PM
Hammond PaulaDirectorAug 26 '25Sale2.3614,00032,99874,909Aug 27 06:37 PM
PAULA HAMMONDDirectorAug 26 '25Proposed Sale2.3614,00032,997Aug 26 04:07 PM
MARC GRASSOOfficerAug 08 '25Proposed Sale2.0076,446152,892Aug 08 05:22 PM
Yaffe KristineDirectorJun 20 '25Sale1.441,0001,44095,409Jun 23 04:05 PM
GRASSO MARCChief Financial OfficerJun 02 '25Sale1.3416,48822,068296,072Jun 04 04:21 PM
Kenkare-Mitra SaraPresident and Head of R&DJun 02 '25Sale1.3423,89031,974512,252Jun 04 04:19 PM
Rosenthal ArnonChief Executive OfficerJun 02 '25Sale1.3452,08769,7132,414,657Jun 04 04:18 PM
Sara Kenkare-MitraOfficerJun 02 '25Proposed Sale1.3323,02030,617May 30 05:10 PM
Marc GrassoOfficerJun 02 '25Proposed Sale1.3315,87321,111May 30 05:10 PM
Arnon RosenthalOfficerJun 02 '25Proposed Sale1.3350,24266,822May 30 05:10 PM
Kenkare-Mitra SaraPresident and Head of R&DMar 03 '25Sale1.4729,07342,662536,142Mar 05 04:05 PM
Rosenthal ArnonChief Executive OfficerMar 03 '25Sale1.4740,33059,1762,466,744Mar 05 04:05 PM
GRASSO MARCChief Financial OfficerMar 03 '25Sale1.4718,09126,547312,560Mar 05 04:05 PM
Romano GaryChief Medical OfficerMar 03 '25Sale1.4716,30623,927332,977Mar 05 04:05 PM
Arnon RosenthalOfficerMar 03 '25Proposed Sale1.6450,24282,397Feb 28 05:05 PM
Gary RomanoOfficerMar 03 '25Proposed Sale1.6414,30623,462Feb 28 05:05 PM
Sara Kenkare-MitraOfficerMar 03 '25Proposed Sale1.6425,51641,846Feb 28 05:05 PM
Marc GrassoOfficerMar 03 '25Proposed Sale1.6415,87326,032Feb 28 05:05 PM