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VRTX

Vertex Pharmaceuticals, Inc.

Jul 26 • 04:00PM ET

495.26

Dollar change +3.00
Percentage change 0.61	%

Healthcare • Biotechnology • USA • NASD

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Held by: VTI VOO QQQ SPY IVV VUG XLV IBB JEPI VHT

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Index	NDX, S&P 500	P/E	32.13	EPS (ttm)	15.41	Insider Own	0.26%	Shs Outstand	257.70M	Perf Week	0.75%
Market Cap	127.80B	Forward P/E	27.33	EPS next Y	18.12	Insider Trans	-17.17%	Shs Float	257.38M	Perf Month	4.49%
Income	4.02B	PEG	2.56	EPS next Q	-11.70	Inst Own	92.51%	Short Float	1.60%	Perf Quarter	24.53%
Sales	10.17B	P/S	12.56	EPS this Y	9.94%	Inst Trans	1.21%	Short Ratio	3.50	Perf Half Y	15.19%
Book/sh	71.80	P/B	6.90	EPS next Y	8.23%	ROA	18.74%	Short Interest	4.12M	Perf Year	40.73%
Cash/sh	39.42	P/C	12.56	EPS next 5Y	12.53%	ROE	24.38%	52W Range	340.20 - 503.99	Perf YTD	21.72%
Dividend Est.	-	P/FCF	34.38	EPS past 5Y	11.42%	ROI	20.86%	52W High	-1.73%	Beta	0.39
Dividend TTM	-	Quick Ratio	3.29	Sales past 5Y	27.16%	Gross Margin	86.85%	52W Low	45.58%	ATR (14)	8.97
Dividend Ex-Date	-	Current Ratio	3.50	EPS Y/Y TTM	22.70%	Oper. Margin	40.81%	RSI (14)	65.62	Volatility	1.81% 1.81%
Employees	5400	Debt/Eq	0.04	Sales Y/Y TTM	12.74%	Profit Margin	39.51%	Recom	1.83	Target Price	490.75
Option/Short	Yes / Yes	LT Debt/Eq	0.04	EPS Q/Q	56.65%	Payout	0.00%	Rel Volume	0.66	Prev Close	492.26
Sales Surprise	4.24%	EPS Surprise	16.87%	Sales Q/Q	14.21%	Earnings	Aug 01 AMC	Avg Volume	1.18M	Price	495.26
SMA20	2.23%	SMA50	5.06%	SMA200	18.78%	Trades		Volume	773,767	Change	0.61%

Date	Action	Analyst	Rating Change	Price Target Change
Jun-27-24	Initiated	Redburn Atlantic	Buy	$545
Apr-11-24	Upgrade	Evercore ISI	In-line → Outperform	$438
Feb-15-24	Initiated	Wolfe Research	Outperform	$515
Feb-06-24	Downgrade	Evercore ISI	Outperform → In-line	$436 → $438
Feb-02-24	Downgrade	Bernstein	Outperform → Mkt Perform
Jan-31-24	Downgrade	Robert W. Baird	Neutral → Underperform	$325
Jan-31-24	Downgrade	Maxim Group	Buy → Hold
Jan-24-24	Downgrade	Canaccord Genuity	Hold → Sell	$332 → $379
Dec-14-23	Reiterated	RBC Capital Mkts	Sector Perform	$347 → $379
May-30-23	Initiated	William Blair	Outperform	$382
May-04-23	Resumed	Piper Sandler	Overweight	$385
Mar-21-23	Initiated	Bernstein	Outperform	$344
Jan-18-23	Initiated	Canaccord Genuity	Hold	$311
Jan-17-23	Upgrade	SVB Leerink	Mkt Perform → Outperform	$374
Dec-19-22	Downgrade	Jefferies	Buy → Hold	$340
Jul-13-22	Initiated	Cantor Fitzgerald	Overweight	$365
Jun-01-22	Upgrade	Maxim Group	Hold → Buy	$325
May-23-22	Initiated	SVB Leerink	Mkt Perform	$265
May-06-22	Downgrade	Robert W. Baird	Outperform → Neutral	$250
May-03-22	Upgrade	Morgan Stanley	Underweight → Equal-Weight	$250

Show Previous Ratings

Jul-25-24 07:20PM	Insider Sale at Vertex Pharmaceuticals Inc (VRTX) by EVP and CMO Carmen Bozic (GuruFocus.com)
01:01PM	Baillie Gifford's Strategic Moves in Q2 2024: A Closer Look at NVIDIA Corp's Impact (GuruFocus.com)
08:15AM	Is Vertex Pharmaceuticals' Monopoly in Danger? (Motley Fool)
04:10AM	3 Reasons to Buy Vertex Pharmaceuticals Stock Like There's No Tomorrow (Motley Fool)
Jul-24-24 07:01PM	Insider Sale: CEO & President Reshma Kewalramani Sells 15,202 Shares of Vertex ... (GuruFocus.com)
05:50PM	Loading…
05:50PM	Vertex Pharmaceuticals (VRTX) Rises As Market Takes a Dip: Key Facts (Zacks)
09:00AM	Here is What to Know Beyond Why Vertex Pharmaceuticals Incorporated (VRTX) is a Trending Stock (Zacks)
03:52AM	Pipeline power: Sionnas AbbVie deal could redefine CF therapeutics (Pharmaceutical Technology)
Jul-23-24 01:54PM	HHS gives thumbs down to bluebirds fertility support programme (Pharmaceutical Technology)
Jul-22-24 06:00PM	Here's Why Vertex Pharmaceuticals (VRTX) Gained But Lagged the Market Today (Zacks)
Jul-21-24 05:06AM	2 Historically Flawless Metrics Suggest the Stock Market Can Plunge: Here Are 3 Stocks I've Sold Ahead of What May Be a Big Move for Wall Street (Motley Fool)
Jul-20-24 06:00AM	3 Monster Stocks in the Making to Buy Right Now (Motley Fool)
Jul-17-24 01:30PM	3 Gene Editing Stocks That Could Grow Your Wealth (InvestorPlace)
Jul-16-24 09:15AM	Genomics plc Announces New Extension and Expansion of Drug Discovery Collaboration with Vertex (PR Newswire)
08:00AM	Vertex taps Orum to hunt for better preconditioning drugs (BioPharma Dive)
04:15AM	Loading…
04:15AM	Could CRISPR Therapeutics Become the Next Vertex Pharmaceuticals? (Motley Fool)
Jul-15-24 06:00PM	Vertex Pharmaceuticals (VRTX) Exceeds Market Returns: Some Facts to Consider (Zacks)
09:00AM	Health Canada Grants Marketing Authorization for TRIKAFTA® (elexacaftor/tezacaftor/ivacaftor and ivacaftor) for People With Cystic Fibrosis Aged 2 Years and Older With Certain Rare Mutations (PR Newswire)
07:15AM	Bull Market and Beyond: 2 Stocks Just Waiting to Soar (Motley Fool)
04:15AM	Stock-Split Watch: 2 Healthcare Stocks That Look Ready to Split (Motley Fool)
Jul-14-24 09:15AM	Got $1,000? 2 Incredible Growth Stocks to Buy and Hold Forever (Motley Fool)
Jul-12-24 07:01PM	Insider Sale: EVP and CMO Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) (GuruFocus.com)
Jul-11-24 08:45AM	1 Biotech Stock to Buy Hand Over Fist and 1 to Avoid (Motley Fool)
Jul-09-24 06:00PM	Vertex Pharmaceuticals (VRTX) Outpaces Stock Market Gains: What You Should Know (Zacks)
07:00AM	The 3 Most Undervalued Gene Editing Stocks to Buy in July 2024 (InvestorPlace)
Jul-08-24 08:00AM	3 No-Brainer Stocks to Buy in July (Motley Fool)
06:00AM	3 Pharma Stocks Already Ushering in the Next Biotech Boom (InvestorPlace)
Jul-06-24 04:15AM	Prediction: This Will Be Vertex Pharmaceuticals' New Billion-Dollar Growth Driver (and It's Coming Soon). (Motley Fool)
Jul-05-24 02:14PM	The 3 Best Biotech Stocks to Buy in July 2024 (InvestorPlace)
07:45AM	1 Stock That Increased 10,000% in 33 Years to Buy and Hold Forever (Motley Fool)
05:45AM	Loading…
05:45AM	Did Vertex Pharmaceuticals Just Invent the Next Ozempic? (Motley Fool)
Jul-04-24 05:50AM	Forget Eli Lilly: 3 Biotech Stocks to Buy Instead (Motley Fool)
Jul-03-24 03:11PM	3 Top-Rated Gene Editing Stocks Actually Making Money (InvestorPlace)
09:13AM	Vertex (VRTX) NDA for Vanza Triple Therapy Accepted by FDA (Zacks)
Jul-02-24 08:33AM	Vertex Announces FDA Acceptance of New Drug Application for Vanzacaftor/Tezacaftor/Deutivacaftor, a Next-In-Class Triple Combination Treatment for Cystic Fibrosis (Business Wire)
06:24AM	3 Under-the-Radar Biotech Stocks With Blockbuster Potential (InvestorPlace)
Jul-01-24 08:40PM	Is CRISPR Therapeutics AG (CRSP) the Best Stock to Buy and Hold for 5 Years? (Insider Monkey)
04:05PM	Vertex to Announce Second Quarter 2024 Financial Results on August 1 (Business Wire)
10:02AM	3 Breakout Biotech Stocks on Track to Double by 2032 (InvestorPlace)
09:30AM	Bull Market Buys: 2 Growth Stocks to Own for the Long Run (Motley Fool)
Jun-29-24 03:07AM	Insider Sale at Vertex Pharmaceuticals Inc (VRTX): EVP and CMO Carmen Bozic Sells 2,280 Shares (GuruFocus.com)
Jun-28-24 07:45AM	2 Superior Growth Stocks to Buy if You Have $1,000 Right Now (Motley Fool)
05:50AM	Prediction: These Could Be the Best-Performing Healthcare Stocks Through 2030 (Motley Fool)
03:31AM	2 Healthcare Stocks That Are Screaming Buys in June (Motley Fool)
Jun-27-24 02:21PM	You've Been Warned! 3 Biotech Stocks to Buy Now or Regret Forever. (InvestorPlace)
09:54AM	Vertex (VRTX) Rises 16.5% YTD: Time to Bet On the Stock? (Zacks)
09:04AM	What Makes Editas Medicine, Inc. (EDIT) One of the Best Small-Cap Stocks with Highest Upside Potential? (Insider Monkey)
08:00AM	Is CRISPR Therapeutics Stock a Buy? One Analyst Thinks the Biotech Is "Very Undervalued." (Motley Fool)
06:40AM	3 Biotech Stocks That Could Make Your Grandchildren Rich (InvestorPlace)
Jun-26-24 04:36PM	Top 10 Small-Cap Stocks with Highest Upside Potential (Insider Monkey)
09:00AM	Vertex Pharmaceuticals Incorporated (VRTX) Is a Trending Stock: Facts to Know Before Betting on It (Zacks)
Jun-25-24 04:12AM	Everyone's Talking About Vertex Pharmaceuticals. Is It Time to Buy? (Motley Fool)
Jun-24-24 06:00PM	Vertex Pharmaceuticals (VRTX) Ascends While Market Falls: Some Facts to Note (Zacks)
10:11AM	Vertex Pharmaceutical Incorporated. (VRTX): Analysts are Bullish on this Healthcare Stock's Strong Financial Performance in Q1 (Insider Monkey)
09:45AM	Here's Why Vertex Pharmaceuticals (VRTX) is a Strong Growth Stock (Zacks)
09:13AM	10 Best Healthcare Stocks to Buy According to Hedge Funds (Insider Monkey)
06:52AM	Vertexs VX-880 shows promise in Phase I/II type 1 diabetes trial (Clinical Trials Arena)
Jun-21-24 03:45PM	Vertex Announces Positive Results From Ongoing Phase 1/2 Study of VX-880 for the Treatment of Type 1 Diabetes Presented at the American Diabetes Association 84th Scientific Sessions (Business Wire)
12:00PM	Reshma Kewalramani Is Guiding Vertex Pharmaceuticals to Its Next Big Thing (Barrons.com)
05:51AM	Forget Eli Lilly, Buy This Magnificent Biotech Stock Instead (Motley Fool)
Jun-20-24 07:09PM	Asian Stocks Set to Track US Lower, Yen in Focus: Markets Wrap (Bloomberg)
Jun-19-24 09:26AM	Vertex Pharmaceuticals (NASDAQ:VRTX): The Best Healthcare Stock to Buy in 2024? (Insider Monkey)
Jun-18-24 06:00PM	Vertex Pharmaceuticals (VRTX) Stock Dips While Market Gains: Key Facts (Zacks)
06:50AM	3 Top Stocks I'd Buy Today and Hold Forever Without Any Hesitation (Motley Fool)
04:30AM	Analyst Recommends 10 Best Stocks to Diversify Your Portfolio Away from Mega-Cap Tech and AI Stocks (Insider Monkey)
Jun-15-24 06:50AM	3 Growth Stocks You Can Buy Right Now Without Any Hesitation (Motley Fool)
Jun-14-24 07:04PM	Vertex Pharmaceuticals Incorporated (VRTX): A Promising Feminist Stock To Buy? (Insider Monkey)
10:33AM	Vertex says Casgevy benefit extends to nearly five years in sickle cell disease (Clinical Trials Arena)
03:03AM	Vertex Presents Positive Long-Term Data On CASGEVY (exagamglogene autotemcel) at the 2024 Annual European Hematology Association (EHA) Congress (Business Wire)
Jun-13-24 07:00PM	Insider Sale: EVP and CMO Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) (GuruFocus.com)
Jun-12-24 05:50PM	Vertex Pharmaceuticals (VRTX) Stock Declines While Market Improves: Some Information for Investors (Zacks)
09:00AM	Investors Heavily Search Vertex Pharmaceuticals Incorporated (VRTX): Here is What You Need to Know (Zacks)
07:45AM	2 Healthcare Stocks to Buy Hand Over Fist in June (Motley Fool)
Jun-09-24 06:20AM	Cathie Wood Goes Bargain Hunting: 2 Stocks She Just Bought (Motley Fool)
Jun-07-24 12:00PM	Vertex Presents New Data at the European Cystic Fibrosis Conference Demonstrating Significant Benefits of Treatment with TRIKAFTA (Business Wire)
Jun-05-24 07:01PM	Insider Sale: EVP & CFO Charles F. Wagner Jr. Sells Shares of Vertex Pharmaceuticals Inc (VRTX) (GuruFocus.com)
11:30AM	Why Is Vertex (VRTX) Up 15.8% Since Last Earnings Report? (Zacks)
Jun-04-24 02:38AM	Insider Sale at Vertex Pharmaceuticals Inc (VRTX) by EVP, Chief Regulatory & Quality ... (GuruFocus.com)
Jun-03-24 04:24PM	Is Vertex Pharmaceuticals Incorporated (NASDAQ:VRTX) the Leading Gene Therapy Stock to Buy Now? (Insider Monkey)
04:17PM	9 Best Gene Therapy Stocks to Buy Now (Insider Monkey)
Jun-02-24 06:00AM	3 No-Brainer Stocks to Buy in June (Motley Fool)
05:47AM	5 Top Stocks to Buy in June (Motley Fool)
Jun-01-24 08:00AM	S&P 500 Giants Lead Five Healthy Stocks Near Buy Points (Investor's Business Daily)
03:12AM	Insider Sale: EVP and CMO Carmen Bozic Sells Shares of Vertex Pharmaceuticals Inc (VRTX) (GuruFocus.com)
May-31-24 02:44AM	Insider Sale: EVP & CFO Charles F. Wagner Jr. Sells Shares of Vertex Pharmaceuticals Inc (VRTX) (GuruFocus.com)
May-30-24 09:45AM	Why Vertex Pharmaceuticals (VRTX) is a Top Growth Stock for the Long-Term (Zacks)
09:00AM	Vertex Pharmaceuticals Incorporated (VRTX) is Attracting Investor Attention: Here is What You Should Know (Zacks)
05:50AM	Should Abbott and DexCom Investors Be Worried About Vertex Pharmaceuticals? (Motley Fool)
May-26-24 10:15AM	Got $500? 3 Pharma Stocks to Buy and Hold Forever (Motley Fool)
09:45AM	Is It Too Late to Buy Vertex Pharmaceuticals Stock? (Motley Fool)
May-25-24 11:10PM	20 Biggest Publicly Traded Biotech Companies (Insider Monkey)
10:00AM	2 Biotech Stocks to Buy in May (Motley Fool)
06:47AM	3 High-Flying Stocks That Could Soar Even More (Motley Fool)
02:41AM	Insider Selling: Director Bruce Sachs Sells Shares of Vertex Pharmaceuticals Inc (VRTX) (GuruFocus.com)
May-24-24 04:28PM	New Pain Drug Could Be Big For Vertex Stock As Shares Score Breakout (Investor's Business Daily)
May-23-24 07:10AM	The 2030 Millionaire's Club: 3 Biotech Stocks to Buy Now (InvestorPlace)
May-22-24 07:06PM	Insider Sale: CEO & President Reshma Kewalramani Sells 15,202 Shares of Vertex ... (GuruFocus.com)
04:40PM	Stocks Step Back After Fed Minutes; Loar, Monday.com, VRTX In Focus (Investor's Business Daily)
04:05PM	Vertex to Participate in Upcoming June Investor Conferences (Business Wire)
May-21-24 11:47AM	Vertex (VRTX) Outperforms Industry on Rapid Pipeline Progress (Zacks)

Vertex Pharmaceuticals, Inc. is a global biotechnology company, which engages in the business of discovering, developing, manufacturing, and commercializing small molecule drugs for patients with serious diseases. The firm focuses on development and commercializing therapies for the treatment of cystic fibrosis, infectious diseases including viral infections such as influenza and bacterial infections, autoimmune diseases such as rheumatoid arthritis, cancer, inflammatory bowel disease and neurological disorders including pain and multiple sclerosis. The company was founded by Joshua S. Boger in 1989 and is headquartered in Boston, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Bozic Carmen	EVP and CMO	Jul 24 '24	Sale	488.46	2,280	1,113,689	25,539	Jul 25 04:06 PM
Kewalramani Reshma	CEO & President	Jul 22 '24	Sale	497.00	15,202	7,555,394	106,172	Jul 24 04:05 PM
Bozic Carmen	EVP and CMO	Jul 10 '24	Sale	487.34	2,280	1,111,135	27,819	Jul 12 04:07 PM
Bozic Carmen	EVP and CMO	Jun 26 '24	Sale	471.72	2,280	1,075,522	30,099	Jun 28 04:04 PM
Atkinson Edward Morrow III	EVP, Chief Technical Ops. Off.	Jun 12 '24	Sale	478.00	7,288	3,483,664	15,972	Jun 13 04:09 PM
Bozic Carmen	EVP and CMO	Jun 12 '24	Sale	478.00	2,280	1,089,840	32,379	Jun 13 04:11 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	Jun 03 '24	Sale	460.00	3,250	1,495,000	47,137	Jun 05 04:11 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Jun 03 '24	Sale	460.00	2,175	1,000,500	49,098	Jun 05 04:08 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	May 31 '24	Sale	445.00	2,250	1,001,250	51,273	Jun 03 04:09 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	May 30 '24	Sale	439.11	2,350	1,031,908	53,523	Jun 03 04:09 PM
Bozic Carmen	EVP and CMO	May 29 '24	Sale	445.56	2,280	1,015,877	34,659	May 31 04:19 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	May 28 '24	Sale	454.79	3,250	1,478,068	50,387	May 30 04:07 PM
Kewalramani Reshma	CEO & President	May 24 '24	Option Exercise	187.53	1,565	293,484	122,939	May 29 04:08 PM
Kewalramani Reshma	CEO & President	May 24 '24	Sale	457.00	1,565	715,205	121,374	May 29 04:08 PM
SACHS BRUCE I	Director	May 22 '24	Option Exercise	93.51	7,073	661,396	47,073	May 24 04:13 PM
SACHS BRUCE I	Director	May 22 '24	Sale	448.00	7,073	3,168,704	40,000	May 24 04:13 PM
Kewalramani Reshma	CEO & President	May 20 '24	Sale	447.00	15,202	6,795,294	121,374	May 22 04:21 PM
Arbuckle Stuart A	EVP, COO	May 15 '24	Sale	430.93	69	29,734	49,691	May 17 04:24 PM
ALTSHULER DAVID	EVP, Chief Scientific Officer	May 15 '24	Sale	430.93	54	23,270	25,813	May 17 04:22 PM
Sachdev Amit	EVP Chief Patient & Ext Af Off	May 15 '24	Sale	430.93	32	13,790	55,325	May 17 04:27 PM
Bhatia Sangeeta N.	Director	May 02 '24	Sale	402.95	467	188,178	4,435	May 03 04:05 PM
Ambrose Kristen	SVP & Chief Accounting Officer	Apr 02 '24	Sale	419.00	240	100,560	7,500	Apr 03 04:02 PM
Arbuckle Stuart A	EVP, COO	Feb 26 '24	Sale	425.70	5,034	2,142,974	49,691	Feb 27 04:37 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 26 '24	Sale	425.70	4,239	1,804,542	25,813	Feb 27 04:24 PM
Sachdev Amit	EVP Chief Patient & Ext Af Off	Feb 26 '24	Sale	425.70	3,004	1,278,803	55,325	Feb 27 04:59 PM
Ambrose Kristen	SVP & Chief Accounting Officer	Feb 26 '24	Sale	425.70	883	375,893	7,965	Feb 27 04:29 PM
Atkinson Edward Morrow III	EVP, Chief Technical Ops. Off.	Feb 26 '24	Sale	425.70	883	375,893	15,972	Feb 27 04:44 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Feb 26 '24	Sale	425.70	354	150,698	55,804	Feb 27 05:02 PM
Arbuckle Stuart A	EVP, COO	Feb 21 '24	Sale	421.77	3,603	1,519,637	59,439	Feb 23 04:12 PM
Sachdev Amit	EVP Chief Patient & Ext Af Off	Feb 21 '24	Sale	421.77	3,191	1,345,868	60,798	Feb 23 04:20 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 21 '24	Sale	421.77	3,002	1,266,154	34,022	Feb 23 04:10 PM
Atkinson Edward Morrow III	EVP, Chief Technical Ops. Off.	Feb 21 '24	Sale	421.77	1,201	506,546	18,509	Feb 23 04:16 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Feb 21 '24	Sale	421.77	360	151,837	59,467	Feb 23 04:28 PM
Arbuckle Stuart A	EVP, COO	Feb 20 '24	Sale	420.79	4,804	2,021,475	63,042	Feb 21 04:19 PM
Sachdev Amit	EVP Chief Patient & Ext Af Off	Feb 20 '24	Sale	420.79	4,254	1,790,041	63,989	Feb 21 04:38 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 20 '24	Sale	420.79	4,002	1,684,002	37,024	Feb 21 04:13 PM
Atkinson Edward Morrow III	EVP, Chief Technical Ops. Off.	Feb 20 '24	Sale	420.79	801	337,053	19,710	Feb 21 04:23 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Feb 20 '24	Sale	420.79	480	201,979	59,827	Feb 21 04:43 PM
LEIDEN JEFFREY M	Executive Chairman	Feb 15 '24	Sale	419.16	4,655	1,951,190	17,896	Feb 16 04:07 PM
LEIDEN JEFFREY M	Executive Chairman	Feb 14 '24	Sale	419.04	4,356	1,825,338	22,551	Feb 16 04:07 PM
LEIDEN JEFFREY M	Executive Chairman	Feb 13 '24	Sale	419.13	737	308,899	26,907	Feb 14 04:04 PM
Arbuckle Stuart A	EVP, COO	Feb 12 '24	Sale	420.24	4,295	1,804,931	75,718	Feb 13 04:51 PM
Sachdev Amit	EVP Chief Patient & Ext Af Off	Feb 12 '24	Sale	420.24	3,222	1,354,013	74,364	Feb 13 05:15 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Feb 12 '24	Sale	420.24	3,145	1,321,655	47,588	Feb 13 04:46 PM
LEIDEN JEFFREY M	Executive Chairman	Feb 12 '24	Sale	419.51	2,656	1,114,205	27,644	Feb 14 04:04 PM
Biller Jonathan	EVP and Chief Legal Officer	Feb 12 '24	Sale	418.77	1,738	727,822	18,280	Feb 13 04:56 PM
Ambrose Kristen	SVP & Chief Accounting Officer	Feb 12 '24	Sale	420.24	1,374	577,410	9,676	Feb 13 04:48 PM
Atkinson Edward Morrow III	EVP, Chief Technical Ops. Off.	Feb 12 '24	Sale	420.24	913	383,679	23,137	Feb 13 04:54 PM
LEIDEN JEFFREY M	Executive Chairman	Jan 08 '24	Sale	419.07	6,648	2,785,977	2,423	Jan 10 04:06 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	Jan 02 '24	Sale	405.00	3,000	1,215,000	43,693	Jan 04 04:17 PM
Kewalramani Reshma	CEO & President	Dec 15 '23	Option Exercise	181.83	17,135	3,115,593	125,846	Dec 19 04:15 PM
Kewalramani Reshma	CEO & President	Dec 15 '23	Sale	407.00	17,135	6,973,945	108,711	Dec 19 04:15 PM
Arbuckle Stuart A	EVP, COO	Dec 13 '23	Option Exercise	187.53	8,603	1,613,321	65,159	Dec 15 04:20 PM
LEIDEN JEFFREY M	Executive Chairman	Dec 13 '23	Sale	399.42	13,354	5,333,799	9,071	Dec 15 04:33 PM
Arbuckle Stuart A	EVP, COO	Dec 13 '23	Sale	399.00	8,603	3,432,597	56,556	Dec 15 04:20 PM
Kewalramani Reshma	CEO & President	Dec 13 '23	Sale	397.00	5,098	2,023,906	108,711	Dec 15 04:23 PM
WAGNER CHARLES F JR	EVP & Chief Financial Officer	Nov 20 '23	Sale	349.88	3,000	1,049,640	46,693	Nov 21 04:07 PM
Sachdev Amit	EVP Chief Patient & Ext Af Off	Nov 15 '23	Sale	369.92	35	12,947	58,814	Nov 17 04:16 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Nov 15 '23	Sale	369.92	19	7,028	32,038	Nov 17 04:11 PM
Bozic Carmen	EVP and CMO	Nov 14 '23	Sale	380.82	5,650	2,151,633	29,302	Nov 16 04:15 PM
Kewalramani Reshma	CEO & President	Nov 13 '23	Sale	377.00	5,097	1,921,569	113,809	Nov 15 04:16 PM
SACHS BRUCE I	Director	Nov 06 '23	Option Exercise	127.54	11,250	1,434,825	51,250	Nov 08 04:11 PM
SACHS BRUCE I	Director	Nov 06 '23	Sale	385.00	11,250	4,331,250	40,000	Nov 08 04:11 PM
Bozic Carmen	EVP and CMO	Oct 31 '23	Sale	355.92	5,651	2,011,304	34,952	Nov 02 04:07 PM
Bozic Carmen	EVP and CMO	Oct 17 '23	Sale	373.25	5,651	2,109,236	40,603	Oct 19 04:18 PM
Bhatia Sangeeta N.	Director	Oct 17 '23	Sale	375.00	243	91,125	3,901	Oct 19 04:13 PM
LEIDEN JEFFREY M	Executive Chairman	Oct 16 '23	Sale	374.00	12,962	4,847,788	22,425	Oct 18 04:17 PM
Bhatia Sangeeta N.	Director	Oct 06 '23	Sale	360.00	242	87,120	4,144	Oct 11 04:14 PM
Bozic Carmen	EVP and CMO	Oct 03 '23	Sale	345.28	5,651	1,951,177	46,254	Oct 05 04:30 PM
Biller Jonathan	EVP and Chief Legal Officer	Oct 02 '23	Sale	346.76	610	211,524	10,569	Oct 03 04:07 PM
Bozic Carmen	EVP and CMO	Sep 19 '23	Sale	351.00	5,651	1,983,501	51,905	Sep 21 04:15 PM
Bozic Carmen	EVP and CMO	Sep 05 '23	Sale	352.66	5,651	1,992,882	57,556	Sep 07 04:29 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Aug 23 '23	Sale	355.00	2,500	887,500	48,637	Aug 25 04:14 PM
Kearney Terrence C	Director	Aug 10 '23	Option Exercise	127.54	10,000	1,275,400	16,536	Aug 14 04:09 PM
Sachdev Amit	EVP, Chief Patient Officer	Aug 10 '23	Sale	350.00	10,031	3,510,850	58,814	Aug 14 04:05 PM
Kearney Terrence C	Director	Aug 10 '23	Sale	350.00	10,000	3,500,000	6,536	Aug 14 04:09 PM
Tatsis Ourania	EVP, Chief Reg. & Quality Off.	Aug 10 '23	Sale	345.79	5,750	1,988,293	51,137	Aug 14 04:08 PM
Bhatia Sangeeta N.	Director	Aug 09 '23	Sale	345.51	242	83,613	4,386	Aug 11 04:05 PM
ALTSHULER DAVID	EVP, Global Research and CSO	Aug 09 '23	Sale	345.51	63	21,767	32,038	Aug 11 04:05 PM

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Vertex Pharmaceuticals, Inc.

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