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PRTA

Prothena Corporation plc

Dec 12 • 04:00PM ET

10.36

+0.03 0.29 %

Healthcare • Biotechnology • Ireland • NASD

Peers: VRTX BIIB ALNY IONS SRPT NBIX EXEL ACAD ARWR CLDX

| Held by: IWM VXF IWN IBB SCHA VTWO DFAS VHT AVSC ITOT

Index	RUT	P/E	-	EPS (ttm)	-5.21	Insider Own	19.39%	Shs Outstand	53.83M	Perf Week	-6.41%
Market Cap	557.68M	Forward P/E	365.69	EPS next Y	0.03	Insider Trans	0.00%	Shs Float	43.39M	Perf Month	-4.52%
Enterprise Value	235.92M	PEG	14.78	EPS next Q	-0.59	Inst Own	79.67%	Short Float	10.69%	Perf Quarter	26.96%
Income	-280.46M	P/S	47.30	EPS this Y	-108.22%	Inst Trans	1.99%	Short Ratio	7.15	Perf Half Y	103.94%
Sales	11.79M	P/B	1.89	EPS next Y	100.60%	ROA	-59.18%	Short Interest	4.64M	Perf YTD	-25.20%
Book/sh	5.48	P/C	1.69	EPS next 5Y	24.74%	ROE	-67.63%	52W High	17.66 -41.34%	Perf Year	-28.80%
Cash/sh	6.15	P/FCF	-	EPS past 3/5Y	- -3.15%	ROIC	-93.12%	52W Low	4.32 139.81%	Perf 3Y	-82.61%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	-12.33% 178.00%	Gross Margin	69.05%	Volatility	5.50% 5.55%	Perf 5Y	-11.53%
Dividend TTM	-	EV/Sales	20.01	EPS Y/Y TTM	-112.24%	Oper. Margin	-1885.68%	ATR (14)	0.57	Perf 10Y	-84.23%
Dividend Ex-Date	-	Quick Ratio	6.61	Sales Y/Y TTM	-91.16%	Profit Margin	-2379.59%	RSI (14)	49.34	Recom	2.17
Dividend Gr. 3/5Y	- -	Current Ratio	6.61	EPS Q/Q	38.12%	SMA20	-0.75%	Beta	-0.11	Target Price	20.80
Payout	-	Debt/Eq	0.03	Sales Q/Q	148.97%	SMA50	0.17%	Rel Volume	0.70	Prev Close	10.33
Employees	163	LT Debt/Eq	0.02	Earnings	Nov 06 AMC	SMA200	15.24%	Avg Volume	648.47K	Price	10.36
IPO	Dec 21, 2012	Option/Short	Yes / Yes	EPS/Sales Surpr.	1.03% -63.62%	Trades		Volume	455,795	Change	0.29%

Date	Action	Analyst	Rating Change	Price Target Change
May-28-25	Downgrade	BofA Securities	Neutral → Underperform	$4
May-27-25	Downgrade	Oppenheimer	Outperform → Perform
May-27-25	Downgrade	Jefferies	Buy → Hold	$6
May-27-25	Downgrade	Cantor Fitzgerald	Overweight → Neutral
Dec-20-24	Initiated	Chardan Capital Markets	Buy	$40
Jan-30-24	Downgrade	BofA Securities	Buy → Neutral	$68 → $38
Dec-12-23	Initiated	Deutsche Bank	Buy	$62
Apr-24-23	Initiated	SVB Securities	Outperform	$80
Jan-27-23	Initiated	Piper Sandler	Overweight	$94
Nov-04-22	Downgrade	RBC Capital Mkts	Outperform → Sector Perform	$52 → $55
Sep-28-22	Upgrade	BofA Securities	Neutral → Buy
Nov-19-21	Initiated	JMP Securities	Mkt Outperform	$77
Jun-18-21	Upgrade	BofA Securities	Underperform → Neutral	$12 → $49
Jun-08-21	Reiterated	Oppenheimer	Outperform	$45 → $54
May-26-21	Initiated	Citigroup	Buy	$39
Feb-26-21	Upgrade	RBC Capital Mkts	Sector Perform → Outperform	$14 → $28
Feb-12-21	Upgrade	Jefferies	Hold → Buy	$15 → $30
Feb-02-21	Upgrade	BTIG Research	Neutral → Buy	$29
Dec-07-20	Initiated	H.C. Wainwright	Buy	$22
Jul-09-20	Upgrade	Oppenheimer	Perform → Outperform	$16

Show Previous Ratings

Dec-12-25 04:05PM	Prothena Announces Board of Directors Update (Business Wire)
Nov-19-25 04:05PM	Prothena Announces Poster Presentation on its TDP-43 CYTOPE Program at Neuroscience 2025 (Business Wire)
Nov-11-25 09:00AM	Prothena Highlights Phase 2 Data for Coramitug (Formerly PRX004) Published in Circulation, Official Journal of AHA (Business Wire)
Nov-07-25 10:32AM	Prothena Q3 Earnings Miss Estimates, Pipeline Progress in Focus (Zacks)
Nov-06-25 05:45PM	Prothena (PRTA) Reports Q3 Loss, Lags Revenue Estimates (Zacks)
04:46PM	Loading…
04:46PM	Prothena: Q3 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports Third Quarter 2025 Financial Results and Business Highlights (Business Wire)
Oct-30-25 04:05PM	Prothena to Report Third Quarter 2025 Financial Results on November 6 (Business Wire)
Oct-22-25 03:33PM	Prothena Corporation plc (PRTA): A Bull Case Theory (Insider Monkey)
Oct-01-25 04:45PM	Prothenas Partner Bristol Myers Squibb Obtains Fast Track Designation from the U.S. FDA for BMS-986446 (PRX005), an Anti-MTBR-Tau-Targeting Antibody, for the Treatment of Alzheimers Disease (Business Wire)
Sep-11-25 10:01AM	Prothena Down 40% Year to Date: What Lies Ahead for the Stock? (Zacks)
Sep-03-25 11:30AM	Prothena (PRTA) Up 17.6% Since Last Earnings Report: Can It Continue? (Zacks)
Aug-28-25 04:05PM	Prothena to Participate in the Cantor Fitzgerald Global Healthcare Conference (Business Wire)
Aug-27-25 04:05PM	Prothena Provides Update on PRX012 and Announces Results from the Phase 1 ASCENT Clinical Program (Business Wire)
Aug-08-25 05:07AM	Elevidys sales weaken; Neumora gets into obesity (BioPharma Dive)
09:00AM	Loading…
Aug-06-25 09:00AM	Prothena Announces that Novo Nordisk Will Advance Coramitug (Formerly PRX004) into Phase 3 Development for ATTR Amyloidosis with Cardiomyopathy (Business Wire) +12.66%
Aug-04-25 05:50PM	Prothena (PRTA) Reports Q2 Loss, Lags Revenue Estimates (Zacks)
04:47PM	Prothena: Q2 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports Second Quarter 2025 Financial Results and Business Highlights (Business Wire)
Jul-30-25 10:01AM	PTC Therapeutics (PTCT) Surges 11.2%: Is This an Indication of Further Gains? (Zacks)
Jul-29-25 10:00AM	Earnings Preview: Rhythm Pharmaceuticals, Inc. (RYTM) Q2 Earnings Expected to Decline (Zacks)
Jul-28-25 04:05PM	Prothena to Report Second Quarter 2025 Financial Results on August 4 (Business Wire)
Jul-24-25 10:46AM	Roche Reports 7% 1H25 Sales Growth, Key Drugs Perform Well (Zacks)
Jul-17-25 01:07PM	AstraZeneca's AL Amyloidosis Drug Misses Goal in Late-Stage Studies (Zacks)
Jul-04-25 01:51PM	PRTA Dives 53.5% YTD: Will the Restructuring Effort Boost Prospects? (Zacks)
Jun-20-25 07:22AM	Prothena to lay off majority of staff; Zealand shares obesity drug data (BioPharma Dive)
Jun-18-25 04:05PM	Prothena Announces Corporate Restructuring (Business Wire)
Jun-17-25 01:30PM	Roche's Phase 3 Move Boosts Outlook for Prothena Corporation plc (PRTA) (Insider Monkey)
09:16AM	Morning Movers: Sage Therapeutics surges after deal to be acquired by Supernus (TipRanks)
Jun-16-25 10:22AM	Roche, waving off study failures, commits to Phase 3 trials for Parkinsons drug (BioPharma Dive) +11.42%
09:49AM	Loading…
09:49AM	RHHBY to Advance Parkinson's Disease Drug to Late-Stage Development (Zacks)
01:06AM	Prothenas Partner Roche to Advance Prasinezumab into Phase III Development for Early-Stage Parkinson's Disease (Business Wire)
May-29-25 03:40PM	Citizens JMP Slashes Prothena (PRTA) to $29 from $78 After AFFIRM-AL Trial Fails (Insider Monkey)
May-28-25 01:55PM	Oppenheimer Downgrades Prothena Corporation (NASDAQ:PRTA) to Perform from Outperform (Insider Monkey)
May-27-25 01:08PM	Jefferies Downgrades Prothena Corporation (PRTA) After Negative Trial Results (Insider Monkey) -30.40%
10:20AM	Prothena's Late-Stage Study for AL Amyloidosis Fails, Stock Down (Zacks)
07:53AM	Biogen strikes RNAi deal with City; Aurion withdraws IPO (BioPharma Dive)
07:43AM	Why Is Prothena Stock Trading Lower On Tuesday? (Benzinga)
May-26-25 06:16AM	Prothenas Phase III trial for AL amyloidosis treatment misses endpoint (Clinical Trials Arena)
May-23-25 04:05PM	Prothena Announces Phase 3 AFFIRM-AL Clinical Trial for Birtamimab in Patients with AL Amyloidosis Did Not Meet Primary Endpoint (Business Wire) -30.40%
May-09-25 01:28PM	Prothena Q1 Earnings Miss Estimates, Focus on Key Readouts in 2025 (Zacks)
08:29AM	Is Prothena Corporation plc (PRTA) the Low Risk High Reward Stock Set to Triple by 2030? (Insider Monkey)
May-08-25 05:50PM	Prothena (PRTA) Reports Q1 Loss, Misses Revenue Estimates (Zacks)
04:47PM	Prothena: Q1 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports First Quarter 2025 Financial Results and Business Highlights (Business Wire)
May-07-25 12:44PM	Prothena Q1 2025 Earnings Preview (Seeking Alpha)
May-01-25 04:05PM	Prothena to Report First Quarter 2025 Financial Results on May 8 (Business Wire) -5.22%
Apr-16-25 11:49AM	Biogen & Partner Eisai Get EU Nod for Alzheimer's Drug Leqembi (Zacks)
Feb-21-25 02:15AM	Prothena Corp PLC (PRTA) Q4 2024 Earnings Call Highlights: Strong Financial Position Amidst ... (GuruFocus.com)
Feb-20-25 05:25PM	Prothena (PRTA) Reports Q4 Loss, Misses Revenue Estimates (Zacks)
04:22PM	Prothena: Q4 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports Fourth Quarter and Full Year 2024 Financial Results, and Provides Financial Guidance and Business Highlights (Business Wire)
Feb-13-25 04:05PM	Prothena to Report Fourth Quarter and Full Year 2024 Financial Results on February 20, 2025 (Business Wire)
Dec-30-24 04:05PM	Prothena Announces Board of Directors Update (Business Wire) -6.92%
Dec-19-24 04:22PM	Prothena Catapults, Flashing A Bullish Sign, On Promise In Parkinson's Disease (Investor's Business Daily) +33.97%
08:09AM	Prothenas Parkinsons study fails primary endpoint despite some success (Clinical Trials Arena)
01:05AM	Roches Phase IIb Study of Prasinezumab Missed Primary Endpoint, But Suggests Possible Clinical Benefit in Early-Stage Parkinsons Disease (Business Wire)
Dec-12-24 11:30AM	Why Is Prothena (PRTA) Down 17.9% Since Last Earnings Report? (Zacks)
Nov-12-24 05:55PM	Prothena (PRTA) Reports Q3 Loss, Misses Revenue Estimates (Zacks)
04:56PM	Prothena: Q3 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports Third Quarter 2024 Financial Results and Business Highlights (Business Wire)
Nov-05-24 04:05PM	Prothena to Report Third Quarter 2024 Financial Results on November 12 (Business Wire) +8.71%
Oct-29-24 12:00PM	Prothena (PRTA) Upgraded to Buy: What Does It Mean for the Stock? (Zacks)
04:48AM	Strength Seen in Prothena (PRTA): Can Its 15.0% Jump Turn into More Strength? (Zacks)
Oct-18-24 03:01PM	State Street Corp's Strategic Reduction in Prothena Corp PLC Holdings (GuruFocus.com)
Sep-27-24 04:05PM	Prothena Announces Leadership Team Updates (Business Wire) -16.56%
Aug-29-24 04:05PM	Prothena to Participate in Upcoming Healthcare Conferences (Business Wire)
Aug-19-24 12:00PM	What Makes Prothena (PRTA) a New Buy Stock (Zacks)
Aug-18-24 12:28AM	Prothena Corporation plc (PTRA): Positioning Among Top Debt-Free Stocks (Insider Monkey)
Aug-17-24 08:22AM	7 Best Debt Free Stocks To Buy (Insider Monkey)
Aug-09-24 09:16AM	Prothena (PRTA) Q2 Earnings Benefit From Collaboration Revenues (Zacks)
Aug-08-24 06:40PM	Prothena (PRTA) Q2 Earnings and Revenues Beat Estimates (Zacks)
05:33PM	Prothena: Q2 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports Second Quarter 2024 Financial Results and Business Highlights (Business Wire)
Aug-01-24 04:05PM	Prothena to Report Second Quarter 2024 Financial Results on August 8 (Business Wire) -5.20%
Jul-25-24 10:02AM	Prothena (PRTA) Expected to Beat Earnings Estimates: What to Know Ahead of Q2 Release (Zacks)
Jun-24-24 08:48AM	Prothena (PRTA) Moves 9.3% Higher: Will This Strength Last? (Zacks)
Jun-11-24 04:07PM	Eli Lilly Seesaws On FDA Win, And Pushes Alzheimer's Stocks Prothena, Eisai Lower (Investor's Business Daily)
12:20PM	Eli Lilly Drags Alzheimer's Stocks Prothena, Eisai Lower Despite FDA Win (Investor's Business Daily)
Jun-07-24 11:30AM	Why Is Prothena (PRTA) Down 1.5% Since Last Earnings Report? (Zacks)
May-29-24 10:26AM	Prothena (PRTA), Bristol Myers Tie Up for Second Neuro Candidate (Zacks)
08:46AM	BMS stakes $80m on Prothenas neurodegenerative candidate (Pharmaceutical Technology)
May-28-24 04:05PM	Prothena Announces Bristol Myers Squibb Opt-in for Exclusive Global License for PRX019, the Second Program from Global Neuroscience Research and Development Collaboration (Business Wire)
May-09-24 11:52AM	Prothena (PRTA) Q1 Earnings Miss Estimates on Higher R&D Expenses (Zacks)
May-08-24 10:56PM	PRTA Stock Earnings: Prothena Corp Misses EPS, Misses Revenue for Q1 2024 (InvestorPlace)
06:10PM	Prothena (PRTA) Reports Q1 Loss, Lags Revenue Estimates (Zacks)
05:14PM	Prothena: Q1 Earnings Snapshot (Associated Press Finance)
04:05PM	Prothena Reports First Quarter 2024 Financial Results and Business Highlights (Business Wire)
May-01-24 04:05PM	Prothena to Report First Quarter 2024 Financial Results on May 8 (Business Wire) +5.31%
Apr-25-24 10:01AM	Earnings Preview: Prothena (PRTA) Q1 Earnings Expected to Decline (Zacks)
Apr-15-24 04:05PM	Prothena Announces Review on Birtamimab Mechanism of Action and Pharmacological Characteristics Published in Leukemia & Lymphoma (Business Wire)
Mar-28-24 08:00AM	Race To Treat Alzheimer's Disease Is Heating Up Despite Eli Lilly's Setback (Investor's Business Daily)
Mar-05-24 04:05PM	Prothena to Participate in Upcoming Healthcare Conferences (Business Wire)
Mar-04-24 04:05PM	Prothena Appoints David Ford to Newly Created Chief People Officer Position (Business Wire)
Feb-21-24 04:05PM	Prothena Announces Appointment of Daniel G. Welch as Director and Chair Designate (Business Wire)
Feb-16-24 01:33PM	Prothena (PRTA) Q4 Earnings Miss Estimates on Higher R&D Expense (Zacks)
10:33AM	Prothena Corporation plc (NASDAQ:PRTA) Q4 2023 Earnings Call Transcript (Insider Monkey)
Feb-15-24 04:50PM	Prothena: Q4 Earnings Snapshot (Associated Press Finance)
04:48PM	Prothena Corp PLC (PRTA) Reports 2023 Financial Results and Provides 2024 Outlook (GuruFocus.com)
04:05PM	Prothena Reports Fourth Quarter and Full Year 2023 Financial Results, and Provides Financial Guidance and Business Highlights (Business Wire)

Prothena Corp. Plc is a clinical-stage neuroscience company, which engages in the discovery and development of novel therapies to change the course of devastating diseases. The firm's clinical pipeline includes both wholly owned and partnered programs being developed for the potential treatment of diseases including AL amyloidosis, ATTR amyloidosis, Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. The company was founded in December 1969 and is headquartered in Dublin, Ireland.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
EcoR1 Capital, LLC	10% Owner	May 02 '25	Sale	8.36	3,317,938	27,744,929	8,266,342	May 06 07:06 PM
EcoR1 Capital, LLC	10% Owner	May 06 '25	Sale	7.64	1,984,053	15,164,712	5,304,596	May 06 07:06 PM
EcoR1 Capital, LLC	10% Owner	May 05 '25	Sale	8.11	977,693	7,930,166	7,288,649	May 06 07:06 PM
SCULLY WILLIAM P	10% Owner	Jan 14 '25	Buy	12.79	100,000	1,279,040	735,993	May 02 10:29 AM
SCULLY WILLIAM P	10% Owner	Dec 18 '24	Buy	13.93	73,436	1,022,670	1,297,693	May 02 10:29 AM
SCULLY WILLIAM P	10% Owner	Dec 31 '24	Buy	13.01	32,000	416,393	650,193	May 02 10:29 AM
SCULLY WILLIAM P	10% Owner	Dec 20 '24	Buy	15.91	2,000	31,813	618,693	May 02 10:29 AM

Open in Screener

ZYME

Zymeworks BC Inc

Dec 12 • 04:00PM ET

25.48

+0.54 2.17 %

Healthcare • Biotechnology • USA • NASD

Peers: AMGN BIIB GILD REGN VRTX INCY ALNY EXEL NBIX IONS

| Held by: IWM VTI IBB IWO DFAS VTWO IWC DFAC VHT SPDW

Index	RUT	P/E	-	EPS (ttm)	-0.85	Insider Own	3.31%	Shs Outstand	75.14M	Perf Week	-4.53%
Market Cap	1.92B	Forward P/E	63.84	EPS next Y	0.40	Insider Trans	0.00%	Shs Float	72.91M	Perf Month	31.54%
Enterprise Value	1.69B	PEG	1.09	EPS next Q	-0.47	Inst Own	99.50%	Short Float	7.69%	Perf Quarter	59.95%
Income	-63.43M	P/S	14.29	EPS this Y	40.22%	Inst Trans	-1.66%	Short Ratio	4.97	Perf Half Y	101.10%
Sales	134.48M	P/B	6.03	EPS next Y	141.21%	ROA	-14.34%	Short Interest	5.61M	Perf YTD	74.04%
Book/sh	4.23	P/C	7.63	EPS next 5Y	58.45%	ROE	-18.46%	52W High	28.49 -10.57%	Perf Year	95.10%
Cash/sh	3.34	P/FCF	-	EPS past 3/5Y	26.71% 15.81%	ROIC	-18.90%	52W Low	9.03 182.17%	Perf 3Y	244.32%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	41.95% 20.90%	Gross Margin	90.49%	Volatility	4.42% 5.78%	Perf 5Y	-53.25%
Dividend TTM	-	EV/Sales	12.55	EPS Y/Y TTM	43.93%	Oper. Margin	-52.51%	ATR (14)	1.35	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	6.94	Sales Y/Y TTM	116.21%	Profit Margin	-47.16%	RSI (14)	59.54	Recom	1.00
Dividend Gr. 3/5Y	- -	Current Ratio	6.94	EPS Q/Q	34.02%	SMA20	1.89%	Beta	1.30	Target Price	35.17
Payout	-	Debt/Eq	0.06	Sales Q/Q	72.59%	SMA50	22.11%	Rel Volume	0.58	Prev Close	24.94
Employees	286	LT Debt/Eq	0.05	Earnings	Nov 06 AMC	SMA200	69.52%	Avg Volume	1.13M	Price	25.48
IPO	Apr 28, 2017	Option/Short	Yes / Yes	EPS/Sales Surpr.	11.77% -7.69%	Trades		Volume	656,382	Change	2.17%

Date	Action	Analyst	Rating Change	Price Target Change
Dec-12-25	Upgrade	Wells Fargo	Equal Weight → Overweight	$33
Dec-03-25	Initiated	Citizens JMP	Mkt Outperform	$32
Oct-24-25	Resumed	Wells Fargo	Equal Weight	$15
Oct-14-25	Upgrade	H.C. Wainwright	Neutral → Buy	$26
Oct-10-25	Initiated	B. Riley Securities	Buy	$30
May-20-25	Initiated	TD Cowen	Buy
Dec-16-24	Upgrade	JP Morgan	Neutral → Overweight	$18
Nov-07-24	Upgrade	Leerink Partners	Market Perform → Outperform	$10 → $25
Nov-01-24	Downgrade	Wells Fargo	Overweight → Equal Weight	$12
Mar-21-23	Resumed	Wells Fargo	Overweight	$12
Jan-04-23	Reiterated	H.C. Wainwright	Neutral	$10 → $8
Dec-20-22	Upgrade	Jefferies	Hold → Buy	$7.70 → $11
Nov-01-22	Downgrade	H.C. Wainwright	Buy → Neutral	$40 → $8
Oct-21-22	Downgrade	SVB Leerink	Outperform → Mkt Perform	$8
Oct-04-22	Resumed	Wells Fargo	Overweight	$45 → $9
May-05-22	Upgrade	Guggenheim	Neutral → Buy	$14
Mar-15-22	Initiated	Evercore ISI	Outperform	$15
Dec-10-21	Upgrade	SVB Leerink	Mkt Perform → Outperform
Nov-17-21	Resumed	Guggenheim	Neutral
Oct-07-21	Initiated	Jefferies	Hold	$32

Show Previous Ratings

Dec-03-25 09:35AM	Oracle initiated, Uber upgraded: Wall Street's top analyst calls (The Fly)
Dec-02-25 04:05PM	Zymeworks Announces Participation in Upcoming Conferences (GlobeNewswire)
Nov-24-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Nov-18-25 12:16PM	JAZZ Hits 52-Week High on Encouraging Gastric Cancer Study Data (Zacks)
03:38AM	Zymeworks to change course, pursue royalty-driven biotech model (BioPharma Dive)
01:01AM	Loading…
01:01AM	Zymeworks Appoints Scott Platshon as Acting Chief Investment Officer (GlobeNewswire)
01:00AM	Zymeworks Announces Strategic Initiative to Optimize Value of Licensed Products by Building a Diversified Portfolio of Revenue-Generating Assets (GlobeNewswire)
Nov-17-25 04:13PM	Stocks to Watch Recap: Alphabet, Tesla, Netflix, Zymeworks (The Wall Street Journal) +29.05%
09:35AM	Stocks to Watch Monday: Alphabet, Tesla, Netflix, Zymeworks (The Wall Street Journal)
09:02AM	Jazz, Zymeworks Catapult On Their 'Sweeping Success' In Gastric Cancer (Investor's Business Daily)
08:10AM	Jazz Pharmaceuticals and Zymeworks Report Positive Cancer Treatment Results. The Stocks Soar. (Barrons.com)
06:00AM	Zymeworks Announces Positive HERIZON-GEA-01 Phase 3 Results Supporting Ziihera (zanidatamab-hrii) as HER2-Targeted Agent-of-Choice and New Standard of Care in First-Line HER2-Positive Locally Advanced or Metastatic Gastroesophageal Adenocarcinoma (GlobeNewswire)
Nov-06-25 05:35PM	Zymeworks Inc. (ZYME) Reports Q3 Loss, Lags Revenue Estimates (Zacks) -8.04%
04:05PM	Zymeworks Provides Corporate Update and Reports Third Quarter 2025 Financial Results (GlobeNewswire)
Nov-04-25 10:00AM	Orchestra BioMed Holdings, Inc. (OBIO) Expected to Beat Earnings Estimates: Can the Stock Move Higher? (Zacks)
10:00AM	Loading…
Oct-30-25 10:00AM	Zymeworks Inc. (ZYME) Expected to Beat Earnings Estimates: What to Know Ahead of Q3 Release (Zacks)
Oct-29-25 12:00PM	Zymeworks (ZYME) Upgraded to Strong Buy: Here's What You Should Know (Zacks)
Oct-28-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Oct-23-25 12:30PM	Zymeworks Presents Initial Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-? at AACR-NCI-EORTC Conference (GlobeNewswire)
Oct-16-25 09:55AM	Wall Street Analysts Believe Zymeworks (ZYME) Could Rally 25.73%: Here's is How to Trade (Zacks)
06:00AM	Zymeworks to Report Third Quarter 2025 Financial Results and Host Conference Call on November 6, 2025 (GlobeNewswire)
Oct-15-25 09:11AM	Next-Generation Targeted Therapies Reshape Precision Oncology Landscape (PR Newswire)
Oct-14-25 12:00PM	Zymeworks Inc. (ZYME) is a Great Momentum Stock: Should You Buy? (Zacks)
Oct-13-25 04:00PM	Zymeworks to Present Clinical Data from the Phase 1 trial of ZW191, an Antibody-Drug Conjugate Targeting Folate Receptor-?, at AACR-NCI-EORTC International Conference (GlobeNewswire)
Oct-10-25 03:20PM	Bitcoin Miner Leads Two Health Care Stocks To New Highs (Investor's Business Daily) +6.74%
09:36AM	Align downgraded, NetEase upgraded: Wall Street's top analyst calls (The Fly)
Oct-09-25 08:30AM	InMed Pharmaceuticals Appoints Mr. Neil Klompas to It's Board of Directors (Newsfile)
06:00AM	Zymeworks Appoints Dr. Adam Schayowitz as Acting Chief Development Officer (GlobeNewswire)
Sep-02-25 12:30PM	Zymeworks Pulls Plug On Early-Stage Cancer Potential As Therapy Unlikely To Provide Benefit (Benzinga) -5.40%
06:00AM	Zymeworks Announces Decision to Discontinue Clinical Development of ZW171, a Mesothelin-directed T cell Engager (GlobeNewswire)
06:00AM	Loading…
Aug-19-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Aug-14-25 11:41AM	Kodiak Q2 Loss Wider Than Expected, Pipeline Development in Focus (Zacks)
Aug-12-25 10:26AM	Immunovant's Q1 Loss Narrower Than Expected, Pipeline in Focus (Zacks)
09:55AM	Zymeworks (ZYME) Could Find a Support Soon, Here's Why You Should Buy the Stock Now (Zacks)
Aug-11-25 06:00AM	Zymeworks Strengthens Board of Directors with Appointments of Greg Ciongoli and Robert E. Landry (GlobeNewswire)
Aug-07-25 06:35PM	Zymeworks Inc. (ZYME) Tops Q2 Earnings and Revenue Estimates (Zacks)
04:05PM	Zymeworks Provides Corporate Update and Reports Second Quarter 2025 Financial Results (GlobeNewswire)
Jul-29-25 11:03AM	Bispecific Antibodies Market Report 2025- 2035, with Profiles of Akeso Biopharma, Alexion, Amgen, Genmab, Immunocore, Linton Pharm, Merck, OncXerna Therapeutics, Zymeworks, and More (GlobeNewswire)
Jul-28-25 06:00AM	Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW251, a Novel Glypican 3-Targeted Topoisomerase 1 Inhibitor Antibody-Drug Conjugate (GlobeNewswire)
Jul-18-25 09:58AM	Zymeworks (ZYME) Surges 7.1%: Is This an Indication of Further Gains? (Zacks)
Jul-17-25 06:00AM	Zymeworks to Report Second Quarter 2025 Financial Results and Host Conference Call on August 7, 2025 (GlobeNewswire) +7.10%
Jul-10-25 12:00PM	Life Sciences BC Announces 2025 Awards Winners, Honouring Excellence in Health Innovation (Business Wire)
Jun-20-25 12:00PM	All You Need to Know About Zymeworks (ZYME) Rating Upgrade to Buy (Zacks)
Jun-04-25 09:55AM	Wall Street Analysts See a 76.74% Upside in Zymeworks (ZYME): Can the Stock Really Move This High? (Zacks)
May-30-25 06:00AM	Zymeworks Announces NMPA Approval of Zanidatamab in China for Adults with Previously Treated, Unresectable or Metastatic HER2-high expression (IHC3+) Biliary Tract Cancer (GlobeNewswire)
May-22-25 05:00PM	Zymeworks Announces Presentations Highlighting Breadth of Oncology Portfolio at Upcoming Medical Conferences (GlobeNewswire)
May-21-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
May-19-25 04:15PM	Zymeworks Presents Preclinical Data on ZW1528 at the American Thoracic Society International Conference (GlobeNewswire) +5.16%
May-14-25 09:55AM	Wall Street Analysts Think Zymeworks (ZYME) Could Surge 83.89%: Read This Before Placing a Bet (Zacks)
May-08-25 05:50PM	Zymeworks Inc. (ZYME) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
04:05PM	Zymeworks Provides Corporate Update and Reports First Quarter 2025 Financial Results (GlobeNewswire)
May-07-25 10:35AM	Zymeworks Inc (ZYME) Q1 2025 Earnings Report Preview: What To Expect (GuruFocus.com)
Apr-30-25 06:33PM	Hope Amidst The Madness As Market Avoids A New Low (Seeking Alpha)
Apr-28-25 05:33PM	Zymeworks: A Strong Buy With Newly-Approved Cancer Drug, Excellent Financials, And Expansive Pipeline (Seeking Alpha)
10:48AM	Zymeworks: Poised For Growth With Platform Validation (Seeking Alpha)
Apr-25-25 01:00PM	Zymeworks Presents New Data from Multiple Development Programs at 2025 AACR Annual Meeting (GlobeNewswire)
Apr-21-25 06:00AM	Zymeworks Appoints Dr. Sabeen Mekan as Senior Vice President, Clinical Development (GlobeNewswire)
Apr-17-25 06:00AM	Zymeworks to Report First Quarter 2025 Financial Results and Host Conference Call on May 8, 2025 (GlobeNewswire)
Apr-09-25 10:13AM	Zymeworks Inc. (ZYME): Among Stocks Insiders Bought in April After Trump's Tariff Rollout (Insider Monkey)
Apr-05-25 11:00AM	Markets Watch Out For Core CPI With Big Banks Set To Report Earnings (Seeking Alpha)
Mar-26-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Mar-25-25 04:30PM	Zymeworks to Present Preclinical Data on T cell Engager and Antibody-Drug Conjugate Platforms in Six Posters at AACR Annual Meeting (GlobeNewswire)
10:49AM	Zymeworks Inc. (ZYME): Among Stocks Receiving the Most Insider Love in March (InsiderMonkey)
Mar-05-25 04:05PM	Zymeworks Provides Corporate Update and Reports Fourth Quarter and Full Year 2024 Financial Results (GlobeNewswire) -7.97%
Mar-04-25 07:09AM	Zymeworks Inc (ZYME) Q4 2024 Earnings Report Preview: What To Look For (GuruFocus.com)
Feb-26-25 06:00AM	Zymeworks Announces Achievement of $14 Million Milestone from GSK Collaboration (GlobeNewswire)
Feb-25-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Feb-18-25 06:00AM	Zymeworks Announces Appointment of Oleg Nodelman to Board of Directors (GlobeNewswire)
Feb-13-25 06:00AM	Zymeworks To Report Fourth Quarter and Full Year 2024 Financial Results and Host Conference Call on March 5, 2025 (GlobeNewswire)
Jan-30-25 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Jan-08-25 04:05PM	Zymeworks Outlines Strategic Priorities and Outlook for 2025 and 2026 (GlobeNewswire) -6.44%
Dec-12-24 08:30AM	Zymeworks Hosts RandD Day Highlighting Continued Clinical Progress in Oncology Programs and Expansion into Autoimmune and Inflammatory Diseases (GlobeNewswire)
08:30AM	Zymeworks Hosts R&D Day Highlighting Continued Clinical Progress in Oncology Programs and Expansion into Autoimmune and Inflammatory Diseases (GlobeNewswire)
Nov-21-24 06:05AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire) -5.98%
06:00AM	FDA Grants U.S. Approval of Ziihera (zanidatamab-hrii) for the Treatment of Adults with Previously Treated, Unresectable or Metastatic HER2-positive (IHC 3+) Biliary Tract Cancer (BTC) (GlobeNewswire)
Nov-05-24 06:00AM	Zymeworks Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating ZW191 in Folate Receptor-? Expressing Advanced Solid Tumors (GlobeNewswire)
Oct-31-24 04:05PM	Zymeworks Provides Corporate Update and Reports Third Quarter 2024 Financial Results (GlobeNewswire)
Oct-30-24 09:14AM	Zymeworks Inc (ZYME) Q3 2024 Earnings Report Preview: What To Look For (GuruFocus.com)
Oct-29-24 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Oct-25-24 06:00AM	Zymeworks Presents New Preclinical Data on Antibody-Drug Conjugate Programs at EORTC-NCI-AACR Conference (GlobeNewswire)
Oct-21-24 06:00AM	Zymeworks Announces First Patient Dosed in Phase 1 Clinical Trial Evaluating ZW171 in Advanced Mesothelin-Expressing Cancers (GlobeNewswire)
Oct-10-24 06:30AM	Zymeworks to Report Third Quarter 2024 Financial Results and Host Conference Call on October 31, 2024 (GlobeNewswire)
Sep-19-24 12:08PM	Cancer Research Sees Major Boost as New Breakthroughs Emerge from Key Oncology Players (PR Newswire)
Sep-18-24 06:00AM	Zymeworks to Present Preclinical Data on Antibody-Drug Conjugate Programs at EORTC-NCI-AACR Conference (GlobeNewswire)
Sep-03-24 04:30PM	Zymeworks Reports Inducement Grant Under Nasdaq Stock Market Rule 5635(c) (GlobeNewswire)
Aug-22-24 06:30AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Aug-01-24 04:10PM	Zymeworks Announces Share Repurchase Program of up to $60 Million of its Common Stock (GlobeNewswire)
04:05PM	Zymeworks Provides Corporate Update and Reports Second Quarter 2024 Financial Results (GlobeNewswire)
Jul-30-24 06:30AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Jul-25-24 04:30PM	Zymeworks Appoints Leone Patterson as Chief Business and Financial Officer (GlobeNewswire)
Jul-22-24 06:00AM	Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW191, a Novel Folate Receptor- Targeted Topoisomerase I Inhibitor Antibody-Drug Conjugate (GlobeNewswire)
Jul-11-24 06:30AM	Zymeworks To Report Second Quarter 2024 Financial Results and Host Conference Call on August 1, 2024 (GlobeNewswire) +6.82%
Jun-17-24 06:00AM	Zymeworks Announces FDA Clearance of Investigational New Drug Application for ZW171, a novel 2+1 T-cell Targeting Bispecific Antibody for Mesothelin-expressing Cancers (GlobeNewswire) -5.53%
Jun-10-24 06:00AM	Zymeworks Announces China NMPA Acceptance of Biologics License Application for Zanidatamab for Second-Line Treatment of Biliary Tract Cancer (GlobeNewswire)
May-28-24 06:30AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
May-19-24 09:00PM	Bragar Eagel & Squire, P.C. Is Investigating Zymeworks, Regeneron, Jabil, and DoubleVerify and Encourages Investors to Contact the Firm (GlobeNewswire)
May-16-24 04:20PM	Kirby McInerney LLP is Investigating Potential Shareholder Claims Against Zymeworks Inc. (ZYME) (Business Wire)
May-02-24 04:05PM	Zymeworks Provides Corporate Update and Reports First Quarter 2024 Financial Results (GlobeNewswire)
Apr-30-24 06:00AM	Zymeworks Announces Participation in Upcoming Investor Conferences (GlobeNewswire)
Apr-11-24 06:00AM	Zymeworks To Report First Quarter 2024 Financial Results and Host Conference Call on May 2, 2024 (GlobeNewswire)

Zymeworks, Inc. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of novel, multifunctional biotherapeutics. Its product includes Zanidatamab, which is a novel bispecific antibody that targets two distinct domains of the human epidermal growth factor receptor 2 (HER2). Zanidatamab's unique binding properties result in multiple mechanisms of action that may enable it to address unmet need in patient populations with HER2-expressing cancers. The company was founded on September 8, 2003 and is headquartered in Middletown, DE.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Derek John Michael Miller	Former Director	Nov 24 '25	Proposed Sale	23.82	118,000	2,810,760		Nov 24 08:00 PM
Neil Gallagher	Former Director	Nov 21 '25	Proposed Sale	23.82	105,000	2,501,100		Nov 21 08:00 PM
EcoR1 Capital, LLC	Director	May 15 '25	Buy	11.43	49,502	565,847	17,877,989	May 19 06:35 PM
EcoR1 Capital, LLC	Director	May 19 '25	Buy	11.78	5,919	69,738	17,883,908	May 19 06:35 PM
EcoR1 Capital, LLC	Director	Apr 16 '25	Buy	11.16	73,953	825,589	17,773,727	Apr 18 03:17 PM
EcoR1 Capital, LLC	Director	Apr 17 '25	Buy	11.52	54,760	630,819	17,828,487	Apr 18 03:17 PM
EcoR1 Capital, LLC	Director	Apr 04 '25	Buy	11.17	196,438	2,193,800	17,699,774	Apr 07 06:34 PM
EcoR1 Capital, LLC	Director	Apr 03 '25	Buy	11.84	120,770	1,430,170	17,503,336	Apr 07 06:34 PM
EcoR1 Capital, LLC	Director	Apr 02 '25	Buy	11.85	74,360	881,017	17,382,566	Apr 02 07:02 PM
EcoR1 Capital, LLC	Director	Apr 01 '25	Buy	11.60	48,658	564,647	17,308,206	Apr 02 07:02 PM
EcoR1 Capital, LLC	Director	Mar 31 '25	Buy	11.75	4,397	51,658	17,259,548	Apr 02 07:02 PM
EcoR1 Capital, LLC	Director	Mar 25 '25	Buy	12.91	53,501	690,452	17,211,303	Mar 27 06:53 PM
EcoR1 Capital, LLC	Director	Mar 26 '25	Buy	12.24	43,848	536,857	17,255,151	Mar 27 06:53 PM
EcoR1 Capital, LLC	Director	Mar 20 '25	Buy	12.93	73,476	949,883	17,104,080	Mar 24 05:45 PM
EcoR1 Capital, LLC	Director	Mar 21 '25	Buy	12.78	31,033	396,518	17,135,113	Mar 24 05:45 PM
EcoR1 Capital, LLC	Director	Mar 24 '25	Buy	13.08	22,689	296,847	17,157,802	Mar 24 05:45 PM
EcoR1 Capital, LLC	Director	Mar 18 '25	Buy	12.65	113,880	1,440,855	16,972,298	Mar 19 06:32 PM
EcoR1 Capital, LLC	Director	Mar 19 '25	Buy	12.64	58,306	737,233	17,030,604	Mar 19 06:32 PM
EcoR1 Capital, LLC	Director	Mar 17 '25	Buy	12.23	56,277	688,465	16,858,418	Mar 19 06:32 PM
EcoR1 Capital, LLC	Director	Mar 13 '25	Buy	12.48	468,356	5,847,237	16,802,141	Mar 13 07:35 PM
EcoR1 Capital, LLC	Director	Mar 11 '25	Buy	11.49	320,690	3,685,851	16,040,851	Mar 13 07:35 PM
EcoR1 Capital, LLC	Director	Mar 12 '25	Buy	12.25	292,934	3,587,826	16,333,785	Mar 13 07:35 PM
EcoR1 Capital, LLC	Director	Jan 16 '25	Buy	13.88	121,681	1,689,541	15,700,413	Jan 21 05:34 PM
EcoR1 Capital, LLC	Director	Jan 17 '25	Buy	13.87	19,748	273,998	15,720,161	Jan 21 05:34 PM
EcoR1 Capital, LLC	Director	Jan 13 '25	Buy	13.39	74,125	992,875	15,485,203	Jan 15 06:12 PM
EcoR1 Capital, LLC	Director	Jan 14 '25	Buy	13.56	54,500	739,265	15,539,703	Jan 15 06:12 PM
EcoR1 Capital, LLC	Director	Jan 15 '25	Buy	14.01	39,029	546,671	15,578,732	Jan 15 06:12 PM
EcoR1 Capital, LLC	Director	Jan 10 '25	Buy	13.13	204,098	2,678,990	15,411,078	Jan 10 06:27 PM
EcoR1 Capital, LLC	Director	Jan 08 '25	Buy	14.07	21,021	295,829	15,206,980	Jan 10 06:27 PM
Moore Paul Andrew	Chief Scientific Officer	Jan 06 '25	Option Exercise	0.00	37,166	0	34,741	Jan 06 08:35 PM
Moore Paul Andrew	Chief Scientific Officer	Jan 06 '25	Sale	14.92	21,200	316,391	14,741	Jan 06 08:35 PM
Galbraith Kenneth	Chair & CEO	Jan 06 '25	Option Exercise	0.00	114,332	0	114,209	Jan 06 08:34 PM
Galbraith Kenneth	Chair & CEO	Jan 06 '25	Sale	14.92	57,291	855,017	47,543	Jan 06 08:34 PM
Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 06 '25	Option Exercise	0.00	20,000	0	20,000	Jan 06 08:19 PM
Smith Jeffrey T L	EVP & Chief Medical Officer	Jan 06 '25	Sale	14.92	11,110	165,807	8,890	Jan 06 08:19 PM
Smith Jeffrey T L	Officer	Jan 06 '25	Proposed Sale	14.46	11,110	160,651		Jan 06 07:50 PM
Moore Paul Andrew	Officer	Jan 06 '25	Proposed Sale	14.46	21,200	306,552		Jan 06 07:43 PM
Galbraith, Kenneth	Officer	Jan 06 '25	Proposed Sale	14.46	57,291	828,428		Jan 06 07:37 PM
EcoR1 Capital, LLC	Director	Jan 02 '25	Buy	14.78	157,880	2,333,403	15,185,959	Jan 02 05:51 PM
EcoR1 Capital, LLC	Director	Dec 31 '24	Buy	14.57	146,501	2,134,446	15,028,079	Jan 02 05:51 PM
EcoR1 Capital, LLC	Director	Dec 30 '24	Buy	14.47	58,988	853,326	14,881,578	Jan 02 05:51 PM
EcoR1 Capital, LLC	Director	Dec 27 '24	Buy	14.49	101,659	1,473,181	14,822,590	Dec 27 06:41 PM
EcoR1 Capital, LLC	Director	Dec 26 '24	Buy	14.38	16,692	240,038	14,720,931	Dec 27 06:41 PM
EcoR1 Capital, LLC	Director	Dec 24 '24	Buy	14.12	11,958	168,896	14,704,239	Dec 27 06:41 PM

Open in Screener

ANAB

AnaptysBio Inc

Dec 12 • 04:00PM ET

44.94

-0.84 -1.83 %

Healthcare • Biotechnology • USA • NASD

Peers: REGN VRTX BMRN ALNY IONS SRPT EXEL BLUE INCY RGEN

| Held by: VTI IWM XBI IBB IWO VXF SCHA VTWO FFTY IWC

Index	RUT	P/E	-	EPS (ttm)	-2.82	Insider Own	5.95%	Shs Outstand	27.58M	Perf Week	1.33%
Market Cap	1.24B	Forward P/E	-	EPS next Y	-3.71	Insider Trans	-2.68%	Shs Float	25.88M	Perf Month	35.81%
Enterprise Value	1.34B	PEG	-	EPS next Q	0.86	Inst Own	112.61%	Short Float	22.66%	Perf Quarter	122.92%
Income	-84.63M	P/S	7.34	EPS this Y	71.54%	Inst Trans	-18.52%	Short Ratio	9.67	Perf Half Y	92.71%
Sales	169.47M	P/B	-	EPS next Y	-154.63%	ROA	-19.99%	Short Interest	5.86M	Perf YTD	239.43%
Book/sh	-1.07	P/C	5.00	EPS next 5Y	2.71%	ROE	-308.02%	52W High	47.86 -6.09%	Perf Year	94.63%
Cash/sh	8.99	P/FCF	-	EPS past 3/5Y	-34.42% -7.30%	ROIC	-26.87%	52W Low	12.21 268.06%	Perf 3Y	61.42%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	13.05% 62.73%	Gross Margin	98.57%	Volatility	5.91% 6.52%	Perf 5Y	87.09%
Dividend TTM	-	EV/Sales	7.92	EPS Y/Y TTM	53.92%	Oper. Margin	-16.92%	ATR (14)	2.56	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	8.68	Sales Y/Y TTM	196.42%	Profit Margin	-49.94%	RSI (14)	67.93	Recom	1.25
Dividend Gr. 3/5Y	- -	Current Ratio	8.68	EPS Q/Q	145.80%	SMA20	8.98%	Beta	0.34	Target Price	62.82
Payout	-	Debt/Eq	-	Sales Q/Q	154.26%	SMA50	21.42%	Rel Volume	0.51	Prev Close	45.78
Employees	136	LT Debt/Eq	-	Earnings	Nov 04 AMC	SMA200	77.72%	Avg Volume	606.32K	Price	44.94
IPO	Jan 26, 2017	Option/Short	Yes / Yes	EPS/Sales Surpr.	142.83% 248.19%	Trades		Volume	309,268	Change	-1.83%

Date	Action	Analyst	Rating Change	Price Target Change
Oct-13-25	Initiated	Barclays	Overweight	$78
Jun-04-25	Upgrade	H.C. Wainwright	Neutral → Buy	$38
Feb-04-25	Initiated	Wolfe Research	Outperform	$25
Dec-11-24	Downgrade	H.C. Wainwright	Buy → Neutral	$52 → $19
Dec-02-24	Downgrade	BTIG Research	Buy → Neutral
Jul-22-24	Initiated	H.C. Wainwright	Buy	$55
Jul-19-24	Upgrade	JP Morgan	Neutral → Overweight	$29 → $69
Apr-16-24	Initiated	Leerink Partners	Outperform	$47
Apr-11-24	Initiated	Wells Fargo	Overweight	$56
Mar-12-24	Upgrade	Wedbush	Neutral → Outperform	$20 → $34
Feb-26-24	Initiated	BTIG Research	Buy	$55
Feb-21-24	Initiated	Stifel	Buy	$50
Feb-16-24	Initiated	Piper Sandler	Overweight	$80
May-22-23	Upgrade	JP Morgan	Underweight → Neutral	$31 → $30
May-18-23	Initiated	TD Cowen	Outperform
Jan-06-23	Downgrade	Raymond James	Outperform → Mkt Perform
Nov-01-22	Upgrade	Guggenheim	Neutral → Buy	$44
Sep-19-22	Resumed	H.C. Wainwright	Buy	$35
Sep-13-22	Downgrade	Truist	Buy → Hold	$50 → $28
Sep-01-22	Initiated	Raymond James	Outperform	$35

Show Previous Ratings

Nov-25-25 04:15PM	Anaptys Announces Participation in December Investor Conferences (GlobeNewswire)
Nov-21-25 04:47PM	AnaptysBio Reverses Higher After Trading Legal Barbs With Pharma Giant GSK (Investor's Business Daily) +5.18% +5.91%
06:14AM	GSK, AnaptysBio Sue Each Other Over Cancer Drug License (The Wall Street Journal)
04:00AM	Anaptys Announces $100 Million Stock Repurchase Plan (GlobeNewswire)
03:50AM	Anaptys Initiates Litigation Against Tesaro, a GSK Subsidiary (GlobeNewswire)
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Nov-12-25 05:20AM	Metagenomi, Ovid CEOs step aside; Cogent soars on unprecedented stomach cancer data (BioPharma Dive)
Nov-10-25 11:25AM	Why AnaptysBio Stock Plummeted, Reversing A 70% Monthlong Run (Investor's Business Daily) -14.30%
09:00AM	Anaptys Announces Phase 2 Trial of Rosnilimab Did Not Meet Primary or Secondary Endpoints at Week 12 in Moderate-to-Severe Ulcerative Colitis (GlobeNewswire)
Nov-04-25 05:50PM	AnaptysBio, Inc. (ANAB) Surpasses Q3 Earnings and Revenue Estimates (Zacks)
04:15PM	Anaptys Announces Third Quarter 2025 Financial Results and Provides Business Update (GlobeNewswire)
04:15PM	Anaptys Announces Participation in November Investor Conferences (GlobeNewswire)
Oct-29-25 10:00AM	Pacira (PCRX) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
09:15AM	Anaptys Announces New Positive Phase 2b Trial Results for Rosnilimab in Rheumatoid Arthritis at ACR Late-Breaking Oral Presentation (GlobeNewswire)
Oct-28-25 10:00AM	AnaptysBio, Inc. (ANAB) Expected to Beat Earnings Estimates: What to Know Ahead of Q3 Release (Zacks)
Oct-13-25 09:15AM	Anaptys Announces Late-Breaking Oral Presentation of Complete Phase 2b Data for Rosnilimab in Rheumatoid Arthritis at Upcoming ACR Convergence 2025 (GlobeNewswire)
04:05PM	Loading…
Sep-29-25 04:05PM	Anaptys to Provide Overview of ANB033, a CD122 antagonist, at Virtual Investor Event on Tuesday, Oct. 14 (GlobeNewswire) +31.59%
04:05PM	Anaptys Announces Intent to Separate Biopharma Operations from Substantial Royalty Assets by Year-end 2026 (GlobeNewswire)
Aug-27-25 04:15PM	Anaptys Announces Participation in September Investor Conferences (GlobeNewswire)
Aug-06-25 05:25PM	AnaptysBio, Inc. (ANAB) Reports Q2 Loss, Tops Revenue Estimates (Zacks) -9.63%
04:15PM	Anaptys Announces Second Quarter 2025 Financial Results and Provides Business Update (GlobeNewswire)
Jul-29-25 10:00AM	AC Immune (ACIU) May Report Negative Earnings: Know the Trend Ahead of Q2 Release (Zacks)
Jun-03-25 04:05PM	Anaptys Announces Positive Rosnilimab Data Updated Through Six Months in Robust Phase 2b Trial in RA (GlobeNewswire) +7.59% -9.57%
May-27-25 04:15PM	Anaptys to Announce Updated Data from Phase 2b Trial of Rosnilimab, a PD-1 Depleter and Agonist, for Rheumatoid Arthritis on June 3, 2025 (GlobeNewswire)
May-12-25 03:53PM	AnaptysBio, Inc. (ANAB): Among the Unstoppable Growth Stocks to Invest in Now (Insider Monkey)
May-05-25 05:45PM	AnaptysBio, Inc. (ANAB) Reports Q1 Loss, Tops Revenue Estimates (Zacks)
04:15PM	Anaptys Announces First Quarter 2025 Financial Results and Provides Business Update (GlobeNewswire)
Apr-17-25 07:00AM	Bright Peak Therapeutics Appoints John Schmid to its Board of Directors (GlobeNewswire) +7.82%
Mar-25-25 09:21AM	AnaptysBio (ANAB) Moves 9.5% Higher: Will This Strength Last? (Zacks)
Mar-24-25 09:15AM	Anaptys Announces Stock Repurchase Plan (GlobeNewswire) +9.54%
Mar-16-25 06:05AM	Wells Fargo Predicts Up to ~440% Rally for These 2 Strong Buy Stocks (TipRanks)
06:55PM	Loading…
Feb-27-25 06:55PM	AnaptysBio, Inc. (ANAB) Reports Q4 Loss, Tops Revenue Estimates (Zacks)
04:15PM	Anaptys Announces Participation in March Investor Conferences (GlobeNewswire)
04:15PM	Anaptys Announces Fourth Quarter and Full Year 2024 Financial Results and Provides Business Update (GlobeNewswire)
Feb-13-25 10:00AM	Truist says AnaptysBio handing of placebo raise doubt about Phase 2 RA data (TipRanks) +19.44%
09:40AM	Is AnaptysBio (ANAB) Stock Outpacing Its Medical Peers This Year? (Zacks)
05:11AM	AnaptysBio (ANAB) Surges 30.5%: Is This an Indication of Further Gains? (Zacks)
Feb-12-25 12:22PM	AnaptysBio achieves highest ever results in Phase II rheumatoid arthritis trial (Clinical Trials Arena) +30.51%
09:23AM	AnaptysBio Whipsaws On Promising Results In Rheumatoid Arthritis Treatment (Investor's Business Daily)
07:30AM	Anaptys Announces Rosnilimab Achieved Positive Results in RA Phase 2b Trial and Highest Ever Reported CDAI LDA Response Over 6 Months (GlobeNewswire)
Feb-11-25 05:30PM	Anaptys to Announce Top-line Data from Phase 2b Trial of Rosnilimab, a PD-1 Depleter and Agonist, in Rheumatoid Arthritis on Feb. 12, 2025 (GlobeNewswire)
Feb-04-25 06:37AM	Vanda and AnaptysBio link for generalised pustular psoriasis therapy (Pharmaceutical Technology)
Feb-03-25 04:15PM	Anaptys to Present at the Guggenheim SMID Cap Biotech Conference (GlobeNewswire) -7.08%
07:30AM	Vanda Pharmaceuticals and Anaptys Announce Exclusive Global License Agreement for Vanda to Develop and Commercialize Imsidolimab, an IL-36R Antagonist (PR Newswire)
Jan-27-25 09:40AM	Are Medical Stocks Lagging AnaptysBio (ANAB) This Year? (Zacks)
Jan-13-25 09:42AM	How AnaptysBio (ANAB) Stock Stands Out in a Strong Industry (Zacks)
Jan-12-25 03:00AM	Big Biotech Fund Loads Up on a Stock That Surged in 2024, and a Loser (Barrons.com)
Jan-07-25 09:15AM	Anaptys to Present at the 43rd Annual J.P. Morgan Healthcare Conference (GlobeNewswire)
Dec-12-24 05:23AM	AnaptysBios atopic dermatitis trial of BTLA agonist misses endpoints (Clinical Trials Arena)
Dec-11-24 02:07PM	AnaptysBio Discontinues Investment In Eczema Candidate After Disappointing Data (Benzinga) -32.83%
08:30AM	Anaptys Announces Phase 2b Trial of ANB032, a BTLA Agonist, Did Not Meet Primary or Secondary Endpoints in Atopic Dermatitis (GlobeNewswire)
Nov-25-24 09:40AM	Are Medical Stocks Lagging AnaptysBio (ANAB) This Year? (Zacks) +8.22%
Nov-08-24 12:00PM	AnaptysBio (ANAB) Upgraded to Buy: What Does It Mean for the Stock? (Zacks)
09:35AM	Down -32.84% in 4 Weeks, Here's Why You Should You Buy the Dip in AnaptysBio (ANAB) (Zacks)
Nov-05-24 05:30PM	AnaptysBio, Inc. (ANAB) Reports Q3 Loss, Tops Revenue Estimates (Zacks) +11.72%
04:15PM	Anaptys Announces Third Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
04:15PM	Anaptys Announces Participation in November and December Investor Conferences (GlobeNewswire)
Aug-29-24 09:15AM	Anaptys Announces Participation in September Investor Conferences (GlobeNewswire)
Aug-23-24 07:26AM	Why AnaptysBio Was Such a Healthy Stock This Week (Motley Fool)
Aug-14-24 04:11PM	AnaptysBio Surges After Sanofi Takes A Stake In $100 Million Offering (Investor's Business Daily) -6.35%
10:05AM	AnaptysBio Hits Five-Year High After Sanofi Takes A Stake In $100 Million Offering (Investor's Business Daily)
05:00AM	Anaptys Announces Pricing of $100 Million Underwritten Registered Direct Offering (GlobeNewswire)
Aug-05-24 09:54PM	ANAB Stock Earnings: AnaptysBio Misses EPS, Misses Revenue for Q2 2024 (InvestorPlace)
05:55PM	AnaptysBio, Inc. (ANAB) Reports Q2 Loss, Misses Revenue Estimates (Zacks)
04:15PM	Anaptys Announces Second Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
Jul-29-24 10:00AM	AnaptysBio, Inc. (ANAB) May Report Negative Earnings: Know the Trend Ahead of Q2 Release (Zacks)
Jul-22-24 02:53PM	AnaptysBio Investigational Arthritis Drug Might Have Better Efficacy Profile Than Eli Lilly's: Analyst (Benzinga) +5.96%
May-09-24 05:45PM	AnaptysBio, Inc. (ANAB) Reports Q1 Loss, Tops Revenue Estimates (Zacks) -10.75%
04:15PM	Anaptys Announces First Quarter 2024 Financial Results and Provides Business Update (GlobeNewswire)
04:10PM	Anaptys Announces Positive Top-Line GEMINI-2 Phase 3 Clinical Trial Results of Imsidolimab (IL-36R) in Generalized Pustular Psoriasis (GPP) (GlobeNewswire)
04:05PM	Anaptys to Receive $50 Million in a Capped Non-Recourse Monetization from Amended Agreement with Sagard in Exchange for Additional Jemperli Royalties (GlobeNewswire)
May-02-24 10:01AM	AnaptysBio, Inc. (ANAB) Expected to Beat Earnings Estimates: Can the Stock Move Higher? (Zacks)
May-01-24 04:51AM	AnaptysBio (ANAB) Soars 14.3%: Is Further Upside Left in the Stock? (Zacks) +6.90%
Apr-24-24 09:00AM	Actym Therapeutics Appoints Thomas Smart as CEO (PR Newswire)
Apr-15-24 02:19PM	BTIG Research Predicts Over 118% Rally for These 3 Stocks (InvestorPlace) -6.34%
Apr-12-24 07:00PM	Why AnaptysBio Stock Zoomed Nearly 8% Higher This Week (Motley Fool) -8.17%
Apr-09-24 02:40PM	Why You Shouldn't Bet Against AnaptysBio (ANAB) Stock. (Zacks)
Mar-14-24 12:00PM	What Makes AnaptysBio, Inc. (ANAB) a New Buy Stock (Zacks)
09:55AM	Wall Street Analysts Believe AnaptysBio, Inc. (ANAB) Could Rally 69.62%: Here's is How to Trade (Zacks)
Mar-11-24 05:30PM	AnaptysBio, Inc. (ANAB) Reports Q4 Loss, Tops Revenue Estimates (Zacks) -5.85% +11.61%
04:15PM	Anaptys Announces Fourth Quarter and Full Year 2023 Financial Results and Provides Business Update (GlobeNewswire)
Feb-29-24 09:15AM	Anaptys to Present at TD Cowen's 44th Annual Health Care Conference and 2024 AAD Annual Meeting (GlobeNewswire)
Feb-28-24 10:00AM	AnaptysBio, Inc. (ANAB) Expected to Beat Earnings Estimates: Should You Buy? (Zacks)
Feb-22-24 04:00AM	13 Best Short Squeeze Stocks To Buy Now (Insider Monkey)
Feb-19-24 05:54AM	Strength Seen in AnaptysBio, Inc. (ANAB): Can Its 5.9% Jump Turn into More Strength? (Zacks)
Jan-31-24 09:15AM	Anaptys to Present at Guggenheim's 6th Annual Biotechnology Conference (GlobeNewswire)
Jan-12-24 03:02PM	AnaptysBio Inc CEO Daniel Faga Sells 6,866 Shares (GuruFocus.com)
Dec-07-23 09:55AM	Does AnaptysBio, Inc. (ANAB) Have the Potential to Rally 69.36% as Wall Street Analysts Expect? (Zacks)
Nov-27-23 04:15PM	Anaptys Expands Immune Cell Modulator Pipeline with Exclusive License to BDCA2 Modulator Antibody Portfolio from Centessa Pharmaceuticals (GlobeNewswire)
Nov-14-23 09:35AM	Down -24.46% in 4 Weeks, Here's Why AnaptysBio, Inc. (ANAB) Looks Ripe for a Turnaround (Zacks) +7.29%
Nov-07-23 04:15PM	Anaptys Named a BioSpace 2024 Best Places to Work Winner (GlobeNewswire) -6.17%
Nov-04-23 05:41AM	AnaptysBio Inc (ANAB) Reports Q3 2023 Financial Results and Business Updates (GuruFocus.com)
Nov-02-23 04:15PM	Anaptys Announces Third Quarter 2023 Financial Results and Provides Business Update (GlobeNewswire) +8.21%
Nov-01-23 09:15AM	Anaptys Announces Participation in November Investor Conferences (GlobeNewswire)
Oct-11-23 09:15AM	Anaptys to Present Phase 1 Data on ANB032, its BTLA Agonist Antibody, at the 32nd EADV Congress (GlobeNewswire)
Oct-09-23 08:27AM	UPDATE 1-AnaptysBio's skin disease drug meets main goal in late-stage study (Reuters)
08:15AM	Anaptys to Provide Overview of Rosnilimab, a PD-1 Agonist, at Virtual R&D Event on Wednesday, Oct. 25 (GlobeNewswire)
08:05AM	AnaptysBio's skin disease drug meets main goal in late-stage study (Reuters)
08:00AM	Anaptys Announces Positive Top-Line Phase 3 Clinical Trial Results of Imsidolimab (IL-36R) in Generalized Pustular Psoriasis (GPP) (GlobeNewswire)
Sep-19-23 03:01PM	Insider Sell: Eric Loumeau Sells 6,000 Shares of AnaptysBio Inc (GuruFocus.com)
Sep-18-23 04:15PM	AnaptysBio Announces Appointment of John Orwin as Chairman of the Board of Directors (GlobeNewswire)

AnaptysBio, Inc. is a clinical stage biotechnology company. engages in the development of antibody product candidates. Its products pipeline include ANB030, ANB030, and Imsidolimab. It also offers SHM platform that replicate the natural process of somatic hypermutation embedded within the human immune system to rapidly develop a diverse range of therapeutic-grade antibodies in vitro. The company was founded by Andrew B. Cubitt, William J. Boyle, Kevin J. Kinsella, and Nicholas B. Lydon in November 2005 and is headquartered in San Diego, CA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	Sep 30 '25	Option Exercise	14.02	5,000	70,100	17,328	Oct 01 04:00 PM
LOUMEAU ERIC J	CHIEF LEGAL OFFICER	Sep 30 '25	Sale	29.00	8,240	238,960	9,088	Oct 01 04:00 PM
ERIC J LOUMEAU	Officer	Sep 30 '25	Proposed Sale	29.00	8,240	238,960		Sep 30 04:13 PM
Orwin John A	Director	Sep 15 '25	Option Exercise	0.00	1,300	0	10,665	Sep 17 04:02 PM
RENTON HOLLINGS	Director	Aug 08 '25	Option Exercise	6.93	10,231	70,901	15,196	Aug 12 04:02 PM
RENTON HOLLINGS	Director	Aug 08 '25	Sale	19.62	10,231	200,714	4,965	Aug 12 04:02 PM
HOLLINGS C RENTON	Director	Aug 08 '25	Proposed Sale	19.62	10,231	200,713		Aug 08 05:10 PM
RENTON HOLLINGS	Director	Jul 02 '25	Option Exercise	6.93	20,925	145,010	25,890	Jul 03 01:34 PM
RENTON HOLLINGS	Director	Jul 02 '25	Sale	23.57	20,925	493,191	4,965	Jul 03 01:34 PM
HOLLINGS C RENTON	Director	Jul 02 '25	Proposed Sale	23.57	20,925	493,190		Jul 02 04:13 PM
FENTON DENNIS M	Director	Jun 18 '25	Sale	23.97	3,015	72,270	4,965	Jun 20 04:07 PM
RENTON HOLLINGS	Director	Jun 18 '25	Sale	23.97	3,015	72,270	4,965	Jun 20 04:06 PM
HOLLINGS C RENTON	Director	Jun 18 '25	Proposed Sale	23.97	3,015	72,270		Jun 18 04:26 PM
DENNIS M FENTON	Director	Jun 18 '25	Proposed Sale	23.97	3,015	72,270		Jun 18 04:06 PM
Jain Rita	Director	Jun 15 '25	Option Exercise	0.00	7,330	0	11,864	Jun 17 06:33 PM
FENTON DENNIS M	Director	Jun 15 '25	Option Exercise	0.00	6,030	0	7,980	Jun 17 06:33 PM
Marquet Magda	Director	Jun 15 '25	Option Exercise	0.00	6,030	0	9,930	Jun 17 06:32 PM
Orwin John A	Director	Jun 15 '25	Option Exercise	0.00	6,030	0	9,365	Jun 17 06:31 PM
RENTON HOLLINGS	Director	Jun 15 '25	Option Exercise	0.00	6,030	0	7,980	Jun 17 06:30 PM
Schmid John P.	Director	Jun 15 '25	Option Exercise	0.00	6,030	0	52,267	Jun 17 06:30 PM
Ware J. Anthony	Director	Jun 15 '25	Option Exercise	0.00	6,030	0	13,530	Jun 17 06:29 PM
Schmid John P.	Director	Jan 13 '25	Option Exercise	6.50	42,337	275,007	46,237	Jan 15 05:04 PM
EcoR1 Capital, LLC	Director	Dec 30 '24	Buy	12.92	65,184	842,060	7,860,180	Jan 02 06:17 PM
EcoR1 Capital, LLC	Director	Dec 31 '24	Buy	12.93	13,268	171,513	7,873,448	Jan 02 06:17 PM
EcoR1 Capital, LLC	Director	Jan 02 '25	Buy	12.95	6,646	86,070	7,880,094	Jan 02 06:17 PM

Open in Screener

TNGX

Tango Therapeutics Inc

Dec 12 • 04:00PM ET

9.35

+0.25 2.75 %

Healthcare • Biotechnology • USA • NASD

TNGX Tango Therapeutics Inc daily Stock Chart

Peers: CRSP NTLA BEAM KRYS PLRX EDIT SGMO FDMT AFMD VCNX

| Held by: VTI XBI IWM DWAS VXF IWN IBB SCHA VTWO IWC

Index	RUT	P/E	-	EPS (ttm)	-0.92	Insider Own	34.17%	Shs Outstand	111.57M	Perf Week	-2.91%
Market Cap	1.26B	Forward P/E	-	EPS next Y	-1.25	Insider Trans	-7.02%	Shs Float	88.66M	Perf Month	21.90%
Enterprise Value	1.14B	PEG	-	EPS next Q	-0.32	Inst Own	72.56%	Short Float	37.50%	Perf Quarter	37.10%
Income	-100.52M	P/S	18.94	EPS this Y	26.81%	Inst Trans	14.11%	Short Ratio	10.25	Perf Half Y	99.36%
Sales	66.50M	P/B	6.52	EPS next Y	-43.17%	ROA	-35.74%	Short Interest	33.25M	Perf YTD	202.59%
Book/sh	1.43	P/C	8.22	EPS next 5Y	-4.76%	ROE	-51.65%	52W High	11.20 -16.52%	Perf Year	182.48%
Cash/sh	1.14	P/FCF	-	EPS past 3/5Y	-8.36% 7.47%	ROIC	-52.44%	52W Low	1.03 807.77%	Perf 3Y	26.35%
Dividend Est.	-	EV/EBITDA	-	Sales past 3/5Y	4.33% 53.11%	Gross Margin	96.36%	Volatility	6.03% 7.26%	Perf 5Y	-14.79%
Dividend TTM	-	EV/Sales	17.15	EPS Y/Y TTM	21.77%	Oper. Margin	-165.91%	ATR (14)	0.65	Perf 10Y	-
Dividend Ex-Date	-	Quick Ratio	8.88	Sales Y/Y TTM	53.28%	Profit Margin	-151.15%	RSI (14)	52.16	Recom	1.20
Dividend Gr. 3/5Y	- -	Current Ratio	8.88	EPS Q/Q	153.24%	SMA20	-1.51%	Beta	1.74	Target Price	13.25
Payout	-	Debt/Eq	0.22	Sales Q/Q	363.61%	SMA50	8.43%	Rel Volume	0.81	Prev Close	9.10
Employees	155	LT Debt/Eq	0.20	Earnings	Nov 04 BMO	SMA200	74.26%	Avg Volume	3.24M	Price	9.35
IPO	Sep 03, 2020	Option/Short	Yes / Yes	EPS/Sales Surpr.	376.68% 0.02%	Trades		Volume	2,622,835	Change	2.75%

Date	Action	Analyst	Rating Change	Price Target Change
Nov-18-25	Initiated	Wolfe Research	Peer Perform
Aug-19-25	Initiated	Piper Sandler	Overweight	$11
Jul-17-24	Initiated	Jefferies	Buy	$19
Apr-04-24	Initiated	Cantor Fitzgerald	Overweight
Feb-12-24	Initiated	Piper Sandler	Overweight	$18
Dec-08-23	Initiated	B. Riley Securities	Buy	$16
Oct-20-22	Upgrade	H.C. Wainwright	Neutral → Buy	$10
Sep-20-21	Initiated	SVB Leerink	Outperform	$25

Dec-12-25 10:47AM	Pancreatic Cancer Survival Gains Accelerate as Novel Therapies Advance (PR Newswire)
Dec-08-25 09:55AM	Can Tango Therapeutics (TNGX) Climb 37.28% to Reach the Level Wall Street Analysts Expect? (Zacks)
Nov-26-25 07:00AM	Tango Therapeutics to Participate in the Piper Sandler 37th Annual Healthcare Conference (GlobeNewswire)
Nov-21-25 07:45PM	Novavax, UniFirst, and More Stocks See Action From Activist Investors (Barrons.com) +12.70%
09:55AM	Wall Street Analysts See a 46.07% Upside in Tango Therapeutics (TNGX): Can the Stock Really Move This High? (Zacks)
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Nov-12-25 07:00AM	Tango Therapeutics to Participate in the 2025 Jefferies Global Healthcare Conference (GlobeNewswire) -8.47%
Nov-04-25 10:15AM	Tango Therapeutics, Inc. (TNGX) Tops Q3 Earnings and Revenue Estimates (Zacks)
09:00AM	Tango Therapeutics Reports Third Quarter 2025 Financial Results and Provides Business Highlights (GlobeNewswire)
Nov-03-25 07:46AM	Tango Therapeutics Inc (TNGX) Q3 2025 Earnings Report Preview: What To Expect (GuruFocus.com)
Oct-31-25 09:55AM	Wall Street Analysts Think Tango Therapeutics (TNGX) Could Surge 52.2%: Read This Before Placing a Bet (Zacks)
Oct-29-25 07:00AM	Tango Therapeutics to Report Third Quarter 2025 Financial Results on Tuesday, November 4, 2025 (GlobeNewswire)
Oct-27-25 12:00PM	Tango Therapeutics (TNGX) Upgraded to Buy: Here's Why (Zacks)
Oct-23-25 07:20AM	Tango Therapeutics Announces $225 Million Financing (GlobeNewswire) -13.05%
07:00AM	Tango Therapeutics Reports Positive Data from Ongoing Phase 1/2 Study with Vopimetostat (TNG462) in Patients with MTAP-deleted Cancers (GlobeNewswire)
Oct-06-25 07:00AM	Tango Therapeutics to Present First Clinical Data from TNG260 at Society for Immunotherapy of Cancer (SITC) Annual Meeting 2025 (GlobeNewswire)
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Sep-17-25 09:27AM	Tango Therapeutics (TNGX) Soars 7.8%: Is Further Upside Left in the Stock? (Zacks)
Aug-26-25 07:00AM	Tango Therapeutics to Participate in the 2025 Cantor Global Healthcare Conference (GlobeNewswire)
Aug-19-25 09:32AM	Palo Alto upgraded, Li Auto downgraded: Wall Street's top analyst calls (The Fly)
Aug-05-25 08:15AM	Tango Therapeutics, Inc. (TNGX) Reports Q2 Loss, Lags Revenue Estimates (Zacks)
07:00AM	Tango Therapeutics Reports Second Quarter 2025 Financial Results and Provides Business Highlights (GlobeNewswire)
Aug-04-25 09:53AM	Tango Therapeutics Inc (TNGX) Q2 2025: Everything You Need To Know Ahead Of Earnings (GuruFocus.com)
Jul-31-25 07:40PM	IGM Biosciences, Inc. (IGMS) Q2 Earnings and Revenues Surpass Estimates (Zacks) +8.11%
Jul-30-25 10:00AM	Mirum Pharmaceuticals, Inc. (MIRM) Expected to Beat Earnings Estimates: What to Know Ahead of Q2 Release (Zacks)
09:55AM	Wall Street Analysts Believe Tango Therapeutics (TNGX) Could Rally 61.46%: Here's is How to Trade (Zacks)
Jul-29-25 10:00AM	Tango Therapeutics, Inc. (TNGX) Expected to Beat Earnings Estimates: Can the Stock Move Higher? (Zacks)
Jul-22-25 07:00AM	Tango Therapeutics to Report Second Quarter 2025 Financial Results on Tuesday, August 5, 2025 (GlobeNewswire)
Jul-14-25 09:55AM	Does Tango Therapeutics (TNGX) Have the Potential to Rally 75.89% as Wall Street Analysts Expect? (Zacks)
Jun-30-25 05:47AM	Tango doses first subject in MTAP-deleted and RAS mutant cancer trial (Clinical Trials Arena)
Jun-27-25 07:00AM	Tango Therapeutics Announces First Patient Dosed in Phase 1/2 Trial of TNG462 plus Revolution Medicines' Daraxonrasib or Zoldonrasib in Patients with RAS-Mutant MTAP-deleted Pancreatic or Lung Cancer (GlobeNewswire)
Jun-23-25 09:07AM	Tango Therapeutics (TNGX) Moves 7.5% Higher: Will This Strength Last? (Zacks)
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May-27-25 07:00AM	Tango Therapeutics to Participate in the 46th Annual Goldman Sachs Global Healthcare Conference (GlobeNewswire) +11.41%
May-21-25 07:00AM	Tango Therapeutics Announces First Patient Dosed in TNG456 Phase 1/2 Trial in Patients With MTAP-deleted Glioblastomas and Other Solid Tumors (GlobeNewswire) -8.70%
May-12-25 08:15AM	Tango Therapeutics, Inc. (TNGX) Reports Q1 Loss, Lags Revenue Estimates (Zacks) +14.91%
07:00AM	Tango Therapeutics Reports First Quarter 2025 Financial Results and Provides Business Highlights (GlobeNewswire)
May-09-25 09:45AM	Tango Therapeutics Inc (TNGX) Q1 2025 Earnings Report Preview: What To Look For (GuruFocus.com)
May-06-25 08:20AM	Beam Therapeutics Inc. (BEAM) Reports Q1 Loss, Misses Revenue Estimates (Zacks) -11.27%
May-05-25 10:00AM	Tango Therapeutics, Inc. (TNGX) May Report Negative Earnings: Know the Trend Ahead of Next Week's Release (Zacks) -5.96%
May-01-25 07:00AM	Tango Therapeutics to Report First Quarter 2025 Financial Results on Monday, May 12, 2025 (GlobeNewswire)
Apr-09-25 05:00AM	Barbara Weber, M.D., Elected to ITM Supervisory Board (GlobeNewswire) +16.53%
Mar-25-25 04:30PM	Tango Therapeutics to Highlight Preclinical Data on Precision Oncology Pipeline with Five Posters at the American Association for Cancer Research (AACR) Annual Meeting 2025 (GlobeNewswire) -5.75% -6.10%
Feb-27-25 07:00AM	Tango Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Business Highlights (GlobeNewswire) -6.44%
Feb-20-25 07:30AM	Tango Therapeutics to Present at Three Upcoming Investment Bank Conferences (GlobeNewswire)
Jan-30-25 07:00AM	Tango Therapeutics to Present at the Guggenheim SMID Cap Biotechnology Conference (GlobeNewswire)
Dec-03-24 07:00AM	Tango Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire) -5.14%
Nov-27-24 07:00AM	Tango Therapeutics to Present at the Piper Sandler 36th Annual Healthcare Conference (Business Wire) +6.25%
Nov-23-24 10:26AM	Tango Therapeutics Inc. (TNGX): Among the Most Promising Cancer Stocks According to Hedge Funds (Insider Monkey)
Nov-06-24 07:05AM	Tango Therapeutics Reports Third Quarter 2024 Financial Results and Provides Business Highlights (Business Wire) -37.45%
07:00AM	Tango Therapeutics Reports Positive TNG462 Clinical Data and Provides Update on PRMT5 Development Program (Business Wire)
Aug-28-24 07:00AM	Tango Therapeutics to Participate in Upcoming Investor Conferences (Business Wire)
Aug-18-24 09:03AM	Jefferies Predicts up to 270% Rally for These 2 Strong Buy Stocks (TipRanks)
Aug-07-24 07:00AM	Tango Therapeutics Reports Second Quarter 2024 Financial Results and Provides Business Highlights (Business Wire)
Jun-14-24 05:10AM	Tango Therapeutics (TNGX) Moves 10.3% Higher: Will This Strength Last? (Zacks) +6.44%
Jun-05-24 07:00AM	Tango Therapeutics to Present at the Goldman Sachs 45th Annual Global Healthcare Conference (Business Wire)
May-23-24 09:18AM	Medivirs licensee, Tango Therapeutics, has discontinued development of its TNG348 clinical program (PR Newswire)
07:00AM	Tango Therapeutics Announces Discontinuation of TNG348 Program (Business Wire)
May-08-24 01:53PM	TNGX Stock Earnings: Tango Therapeutics Misses EPS, Misses Revenue for Q1 2024 (InvestorPlace)
08:10AM	Tango Therapeutics, Inc. (TNGX) Reports Q1 Loss, Misses Revenue Estimates (Zacks)
07:00AM	Tango Therapeutics Reports First Quarter 2024 Financial Results and Provides Business Highlights (Business Wire)
May-07-24 10:00AM	Will Tango Therapeutics, Inc. (TNGX) Report Negative Q1 Earnings? What You Should Know (Zacks)
Apr-01-24 04:48PM	Tango Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (Business Wire)
Mar-20-24 05:31AM	Tango Therapeutics Inc (TNGX) Reports Full Year and Q4 2023 Financial Results (GuruFocus.com)
Mar-18-24 02:52PM	TNGX Stock Earnings: Tango Therapeutics Misses EPS, Misses Revenue for Q4 2023 (InvestorPlace) -7.09%
08:10AM	Tango Therapeutics, Inc. (TNGX) Reports Q4 Loss, Lags Revenue Estimates (Zacks)
07:00AM	Tango Therapeutics Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Business Highlights (Business Wire)
Mar-17-24 05:20PM	11 Oversold Biotech Stocks To Buy Right Now (Insider Monkey)
Mar-06-24 07:00AM	Tango Therapeutics to Participate in Upcoming Investor Conferences (Business Wire)
Mar-05-24 04:47PM	Tango Therapeutics to Highlight Preclinical Data on Precision Oncology Pipeline at the American Association for Cancer Research (AACR) Annual Meeting 2024 (GlobeNewswire)
Feb-07-24 08:55AM	Pancreatic Cancer Treatments Poised for Major Advances in 2024 (PR Newswire)
Jan-31-24 07:00AM	Tango Therapeutics to Present at the Guggenheim Healthcare Talks 6th Annual Biotechnology Conference (GlobeNewswire)
Jan-05-24 04:05PM	Tango Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Jan-04-24 02:47AM	Medivirs licensee, Tango Therapeutics, has dosed the first patient with TNG348, a novel USP1 inhibitor, in a phase 1/2 clinical study (PR Newswire)
Jan-03-24 07:00AM	Tango Therapeutics Announces First Patient Dosed in Phase 1/2 Trial of TNG348 in Patients with BRCA1/2-Mutant and Other HRD+ Cancers (GlobeNewswire)
Nov-13-23 07:00AM	Tango Therapeutics to Highlight Preclinical Data on PRMT5 Inhibitors at the Society for Neuro-Oncology (SNO) 28th Annual Meeting (GlobeNewswire) -9.45%
Nov-08-23 03:12PM	Tango Therapeutics Inc (TNGX) Reports Q3 2023 Financial Results and Business Updates (GuruFocus.com)
07:00AM	Tango Therapeutics Reports Third Quarter 2023 Financial Results and Provides Business Highlights (GlobeNewswire)
Nov-07-23 07:00AM	Tango Therapeutics to Present at the Jefferies London Healthcare Conference (GlobeNewswire)
Oct-10-23 11:28AM	Tango Therapeutics (TNGX) Rises 20% in a Month: Here's Why (Zacks)
Oct-09-23 08:50AM	What Makes Tango Therapeutics, Inc. (TNGX) a Good Fit for 'Trend Investing' (Zacks) -13.27%
Sep-18-23 07:00AM	Tango Therapeutics to Highlight Preclinical Data on Precision Oncology Pipeline at AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (GlobeNewswire) +5.88%
Sep-06-23 07:00AM	Tango Therapeutics Announces FDA Clearance of Investigational New Drug Application for TNG348, a Novel USP1 Inhibitor for the Treatment of BRCA1/2-mutant and Other HRD+ Cancers (GlobeNewswire)
Sep-05-23 07:00AM	Tango Therapeutics to Participate in the H.C. Wainwright 25th Annual Global Investment Conference (GlobeNewswire)
Aug-29-23 05:08PM	Tango Therapeutics Announces Updates to Its Board of Directors (GlobeNewswire) -7.51%
Aug-28-23 07:00AM	Medicenna Announces the Appointment of Jeff Caravella as Chief Financial Officer (GlobeNewswire)
Aug-10-23 07:00AM	Tango Therapeutics Announces $80 million Private Placement Financing (GlobeNewswire) -16.26%
Aug-07-23 07:00AM	Tango Therapeutics Reports Second Quarter 2023 Financial Results and Provides Business Highlights (GlobeNewswire)
Jul-24-23 07:00AM	Tango Therapeutics Announces First Patient Dosed in TNG260 Phase 1/2 Trial in Patients With STK11-Mutant Cancers (GlobeNewswire)
Jul-10-23 07:00AM	Tango Therapeutics Announces First Patient Dosed in TNG462 Phase 1/2 Trial in Patients With MTAP-deleted Solid Tumors (GlobeNewswire)
Jun-01-23 07:00AM	Tango Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire)
May-09-23 07:00AM	Tango Therapeutics Reports First Quarter 2023 Financial Results and Provides Business Highlights (GlobeNewswire) +6.40%
Apr-18-23 04:30PM	Tango Therapeutics Presents Preclinical Data on Precision Oncology Programs at the American Association of Cancer Research 2023 Annual Meeting (GlobeNewswire) -11.67%
Apr-03-23 07:00AM	Tango Therapeutics Announces FDA Clearance of Investigational New Drug Application for TNG260, a First-in-Class CoREST Inhibitor for the Treatment of STK11-Mutant Cancers (GlobeNewswire) +10.38%
Mar-27-23 07:00AM	Tango Therapeutics Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Business Highlights (GlobeNewswire) -9.35%
Mar-14-23 08:11PM	Tango Therapeutics to Highlight Preclinical Data on Precision Oncology Programs at the American Association of Cancer Research 2023 Annual Meeting (GlobeNewswire)
Mar-10-23 10:15PM	Tango Therapeutics Announces Limited Exposure to Silicon Valley Bank (GlobeNewswire) -13.33% +6.45%
Mar-06-23 07:00AM	Tango Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) (GlobeNewswire)
Mar-01-23 07:00AM	Tango Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire)
Feb-28-23 07:00AM	Tango Therapeutics Announces Appointment of Adam Crystal, M.D., Ph.D. as President of Research and Development (GlobeNewswire) +6.09%
Feb-02-23 07:00AM	Tango Therapeutics to Participate in Upcoming Investor Conferences (GlobeNewswire)
Jan-25-23 07:00AM	Tango Therapeutics Announces FDA Clearance of Investigational New Drug Application for TNG462; Provides Additional Business Updates (GlobeNewswire)
Dec-15-22 07:00AM	HOOKIPA Pharma Appoints Katia Schlienger, M.D., Ph.D., Chief Medical Officer and Malte Peters, M.D., to Board of Directors (GlobeNewswire)

Tango Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in discovering and delivering precision cancer medicines. It also identifies novel targets and develops new drugs directed at tumor suppressor gene loss in defined patient populations with high unmet medical need. The company was founded by Alan Ashworth, William G. Kaelin Jr., Jose Baselga, and Antoni Ribas in 2017 and is headquartered in Boston, MA.

Insider Trading	Relationship	Date	Transaction	Cost	#Shares	Value ($)	#Shares Total	SEC Form 4
Third Rock Ventures IV, L.P.	10% Owner	Oct 23 '25	Sale	10.15	477,401	4,846,575	13,386,574	Oct 27 04:15 PM
Third Rock Ventures IV, L.P.	10% Owner	Oct 23 '25	Proposed Sale	7.53	477,401	3,594,830		Oct 23 05:10 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 25 '25	Sale	8.02	500,000	4,008,500	13,863,975	Sep 29 04:15 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 25 '25	Proposed Sale	7.80	500,000	3,900,000		Sep 25 04:58 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 16 '25	Sale	7.04	363,541	2,559,329	14,363,975	Sep 17 06:06 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 16 '25	Proposed Sale	7.35	363,541	2,672,026		Sep 17 10:29 AM
Third Rock Ventures IV, L.P.	10% Owner	Sep 05 '25	Sale	7.00	642,906	4,500,342	14,813,975	Sep 09 04:15 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 08 '25	Sale	7.04	86,459	608,628	14,727,516	Sep 09 04:15 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 08 '25	Proposed Sale	7.04	86,459	608,628		Sep 08 05:22 PM
Third Rock Ventures IV, L.P.	10% Owner	Sep 05 '25	Proposed Sale	6.94	642,906	4,461,767		Sep 05 06:08 PM
Third Rock Ventures IV, L.P.	10% Owner	Aug 22 '25	Sale	7.00	302,194	2,115,358	15,456,881	Aug 26 04:15 PM
Third Rock Ventures IV, L.P.	10% Owner	Aug 22 '25	Proposed Sale	6.90	302,194	2,085,139		Aug 22 05:26 PM
Third Rock Ventures IV, L.P.	10% Owner	Aug 19 '25	Sale	7.01	1,100,000	7,712,760	15,759,075	Aug 21 04:15 PM
Third Rock Ventures IV, L.P.	10% Owner	Aug 19 '25	Proposed Sale	6.96	1,100,000	7,656,000		Aug 19 07:25 PM
Barry Douglas	General Counsel	Feb 04 '25	Sale	2.99	2,774	8,289	68,570	Feb 06 08:21 PM
Barry Douglas	General Counsel	Feb 05 '25	Sale	3.16	2,556	8,081	66,014	Feb 06 08:21 PM
Beckman Daniella	Chief Financial Officer	Feb 04 '25	Sale	2.99	4,284	12,801	154,232	Feb 06 08:10 PM
Beckman Daniella	Chief Financial Officer	Feb 05 '25	Sale	3.16	3,948	12,481	150,284	Feb 06 08:10 PM
Crystal Adam	See Remarks	Feb 04 '25	Sale	2.99	7,432	22,207	165,061	Feb 06 08:08 PM
Crystal Adam	See Remarks	Feb 05 '25	Sale	3.16	6,851	21,659	158,210	Feb 06 08:08 PM
Weber Barbara	Chief Executive Officer	Feb 04 '25	Sale	2.99	9,778	29,217	1,631,264	Feb 06 08:02 PM
Weber Barbara	Chief Executive Officer	Feb 05 '25	Sale	3.16	9,013	28,494	1,622,251	Feb 06 08:02 PM

PRTA

Prothena Corporation plc

ZYME

Zymeworks BC Inc

ANAB

AnaptysBio Inc

TNGX

Tango Therapeutics Inc

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