Index RUT
P/E -
EPS (ttm) -2.80
Insider Own 13.65%
Shs Outstand 53.68M
Perf Week 4.18%
Market Cap 1.15B
Forward P/E -
EPS next Y -4.10
Insider Trans -0.20%
Shs Float 46.39M
Perf Month -10.56%
Income -147.03M
PEG -
EPS next Q -1.16
Inst Own 98.23%
Short Float 14.29%
Perf Quarter -24.55%
Sales 91.37M
P/S 12.59
EPS this Y -73.59%
Inst Trans -4.11%
Short Ratio 10.30
Perf Half Y -39.61%
Book/sh 10.46
P/B 2.05
EPS next Y 14.39%
ROA -20.22%
Short Interest 6.63M
Perf Year -60.19%
Cash/sh 11.54
P/C 1.86
EPS next 5Y 34.07%
ROE -24.85%
52W Range 19.65 - 79.65
Perf YTD -41.06%
Dividend Est. -
P/FCF -
EPS past 5Y 6.83%
ROI -25.70%
52W High -73.11%
Beta 0.30
Dividend TTM -
Quick Ratio 11.24
Sales past 5Y 4680.14%
Gross Margin 77.94%
52W Low 9.01%
ATR (14) 1.21
Dividend Ex-Date -
Current Ratio 11.24
EPS Y/Y TTM -10.63%
Oper. Margin -209.08%
RSI (14) 42.29
Volatility 5.64% 5.30%
Employees 173
Debt/Eq 0.02
Sales Y/Y TTM 69.50%
Profit Margin -160.91%
Recom 1.44
Target Price 68.50
Option/Short Yes / Yes
LT Debt/Eq 0.02
EPS Q/Q -1169.13%
Payout -
Rel Volume 1.10
Prev Close 20.34
Sales Surprise -85.32%
EPS Surprise -7.18%
Sales Q/Q -99.37%
Earnings Feb 15 AMC
Avg Volume 643.36K
Price 21.42
SMA20 -2.16%
SMA50 -14.31%
SMA200 -45.52%
Trades
Volume 708,995
Change 5.31%
Date
Action
Analyst
Rating Change
Price Target Change
Jan-30-24 Downgrade
BofA Securities
Buy → Neutral
$68 → $38
Dec-12-23 Initiated
Deutsche Bank
Buy
$62
Apr-24-23 Initiated
SVB Securities
Outperform
$80
Jan-27-23 Initiated
Piper Sandler
Overweight
$94
Nov-04-22 Downgrade
RBC Capital Mkts
Outperform → Sector Perform
$52 → $55
Sep-28-22 Upgrade
BofA Securities
Neutral → Buy
Nov-19-21 Initiated
JMP Securities
Mkt Outperform
$77
Jun-18-21 Upgrade
BofA Securities
Underperform → Neutral
$12 → $49
Jun-08-21 Reiterated
Oppenheimer
Outperform
$45 → $54
May-26-21 Initiated
Citigroup
Buy
$39
Feb-26-21 Upgrade
RBC Capital Mkts
Sector Perform → Outperform
$14 → $28
Feb-12-21 Upgrade
Jefferies
Hold → Buy
$15 → $30
Feb-02-21 Upgrade
BTIG Research
Neutral → Buy
$29
Dec-07-20 Initiated
H.C. Wainwright
Buy
$22
Jul-09-20 Upgrade
Oppenheimer
Perform → Outperform
$16
Nov-19-19 Upgrade
Evercore ISI
In-line → Outperform
$14
May-21-18 Downgrade
Barclays
Equal Weight → Underweight
$14 → $12
Apr-23-18 Downgrade
Jefferies
Buy → Hold
Apr-05-18 Reiterated
Barclays
Overweight
$70 → $50
Nov-20-17 Downgrade
Wedbush
Outperform → Neutral
$75 → $55
Show Previous Ratings
May-01-24 04:05PM
Apr-25-24 10:01AM
Apr-15-24 04:05PM
Mar-28-24 08:00AM
(Investor's Business Daily)
Mar-05-24 04:05PM
04:05PM
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Mar-04-24 04:05PM
Feb-21-24 04:05PM
Feb-16-24 01:33PM
10:33AM
Feb-15-24 04:50PM
(Associated Press Finance)
04:48PM
04:05PM
Feb-08-24 04:05PM
Jan-24-24 11:02PM
Jan-10-24 12:06PM
05:38AM
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05:38AM
Jan-08-24 08:30AM
Dec-21-23 09:01AM
Dec-17-23 05:41AM
Dec-01-23 11:05AM
Nov-29-23 08:35AM
(Investor's Business Daily)
Nov-20-23 06:00AM
Nov-17-23 01:35PM
08:15AM
(Investor's Business Daily)
Nov-03-23 11:34AM
Nov-02-23 07:03PM
06:25PM
05:24PM
(Associated Press Finance)
04:05PM
Oct-30-23 10:00AM
04:09PM
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Oct-26-23 04:09PM
(Investor's Business Daily) -14.62%
04:05PM
10:02AM
05:02AM
Oct-18-23 11:20AM
Oct-17-23 07:57AM
Oct-16-23 11:54AM
11:42AM
Oct-12-23 05:01AM
Oct-07-23 03:33PM
Oct-05-23 09:01AM
Sep-28-23 05:01AM
Sep-19-23 09:01PM
Sep-14-23 01:32PM
Sep-07-23 12:00PM
Aug-31-23 04:05PM
Aug-04-23 09:13AM
Aug-03-23 05:55PM
04:49PM
04:05PM
Aug-02-23 07:57AM
Jul-27-23 04:05PM
Jul-18-23 05:36PM
05:36PM
11:30AM
Jul-17-23 08:35AM
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Jul-11-23 04:05PM
08:59AM
Jul-10-23 04:10PM
Jul-07-23 09:51AM
Jun-27-23 04:05PM
Jun-12-23 09:25AM
Jun-08-23 12:41PM
Jun-02-23 04:05PM
May-16-23 04:05PM
May-10-23 06:13AM
May-05-23 12:27PM
May-04-23 06:45PM
05:39PM
04:05PM
Apr-27-23 04:05PM
10:02AM
Apr-24-23 04:05PM
Apr-18-23 02:34PM
Apr-14-23 07:30AM
Apr-13-23 08:00AM
Apr-06-23 01:49PM
Mar-31-23 09:20AM
Mar-21-23 04:05PM
Mar-14-23 04:05PM
Mar-01-23 05:20AM
Feb-24-23 11:36AM
Feb-23-23 04:05PM
Feb-16-23 04:05PM
Feb-05-23 05:03AM
Feb-03-23 04:05PM
Feb-01-23 10:48AM
Jan-31-23 04:05PM
Jan-15-23 09:01AM
Dec-14-22 10:38PM
Dec-13-22 04:12PM
Dec-12-22 11:30AM
Nov-29-22 12:42PM
Nov-22-22 10:07AM
Nov-21-22 04:05PM
Nov-14-22 02:34PM
Nov-09-22 06:07AM
Nov-07-22 09:11AM
Nov-04-22 11:13AM
Prothena Corp. Plc is a clinical-stage neuroscience company, which engages in the discovery and development of novel therapies to change the course of devastating diseases. The firm's clinical pipeline includes both wholly owned and partnered programs being developed for the potential treatment of diseases including AL amyloidosis, ATTR amyloidosis, Alzheimer's disease, Parkinson's disease and other neurodegenerative diseases. The company was founded in December 1969 and is headquartered in Dublin, Ireland.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
Walker Karin L Chief Accounting Officer Jan 24 '24 Option Exercise 13.53 5,000 67,650 5,000 Jan 24 07:01 PM Walker Karin L Chief Accounting Officer Jan 24 '24 Sale 34.00 5,000 170,000 0 Jan 24 07:01 PM Walker Karin L Chief Accounting Officer Dec 20 '23 Option Exercise 13.53 5,000 67,650 5,000 Dec 20 07:17 PM Walker Karin L Chief Accounting Officer Dec 20 '23 Sale 37.19 5,000 185,952 0 Dec 20 07:17 PM Walker Karin L Chief Accounting Officer Nov 30 '23 Option Exercise 13.53 5,000 67,650 5,000 Nov 30 06:24 PM Walker Karin L Chief Accounting Officer Nov 30 '23 Sale 34.00 5,000 170,000 0 Nov 30 06:24 PM Walker Karin L Chief Accounting Officer Oct 25 '23 Option Exercise 13.53 5,000 67,650 5,000 Oct 25 08:03 PM Walker Karin L Chief Accounting Officer Oct 25 '23 Sale 41.04 5,000 205,191 0 Oct 25 08:03 PM Smith Brandon S. Chief Operating Officer Oct 11 '23 Option Exercise 11.12 4,000 44,480 4,000 Oct 11 08:25 PM Smith Brandon S. Chief Operating Officer Oct 11 '23 Sale 46.75 4,000 186,985 0 Oct 11 08:25 PM Karp Carol D. Chief Regulatory Officer Oct 04 '23 Option Exercise 12.15 5,000 60,750 5,000 Oct 04 07:52 PM Karp Carol D. Chief Regulatory Officer Oct 04 '23 Sale 46.62 5,000 233,084 0 Oct 04 07:52 PM Malecek Michael J Chief Legal Officer Sep 27 '23 Option Exercise 10.27 5,000 51,350 5,000 Sep 27 08:35 PM Malecek Michael J Chief Legal Officer Sep 27 '23 Sale 47.38 5,000 236,885 0 Sep 27 08:35 PM Walker Karin L Chief Accounting Officer Sep 19 '23 Option Exercise 15.04 5,000 75,200 5,000 Sep 19 05:37 PM Walker Karin L Chief Accounting Officer Sep 19 '23 Sale 52.36 5,000 261,807 0 Sep 19 05:37 PM Garren Hideki Chief Medical Officer Sep 13 '23 Option Exercise 24.90 2,000 49,800 2,000 Sep 13 07:33 PM Smith Brandon S. Chief Operating Officer Sep 13 '23 Option Exercise 11.12 4,000 44,480 4,000 Sep 13 07:32 PM Smith Brandon S. Chief Operating Officer Sep 13 '23 Sale 55.49 4,000 221,963 0 Sep 13 07:32 PM Garren Hideki Chief Medical Officer Sep 13 '23 Sale 55.48 2,000 110,952 0 Sep 13 07:33 PM Karp Carol D. Chief Regulatory Officer Sep 06 '23 Option Exercise 12.15 5,000 60,750 5,000 Sep 06 07:42 PM Karp Carol D. Chief Regulatory Officer Sep 06 '23 Sale 54.76 5,000 273,804 0 Sep 06 07:42 PM Malecek Michael J Chief Legal Officer Aug 30 '23 Option Exercise 10.27 5,000 51,350 5,000 Aug 30 07:24 PM Malecek Michael J Chief Legal Officer Aug 30 '23 Sale 55.01 5,000 275,066 0 Aug 30 07:24 PM Walker Karin L Chief Accounting Officer Aug 18 '23 Option Exercise 15.04 5,000 75,200 5,000 Aug 18 08:37 PM Walker Karin L Chief Accounting Officer Aug 18 '23 Sale 57.18 5,000 285,922 0 Aug 18 08:37 PM Garren Hideki Chief Medical Officer Aug 16 '23 Option Exercise 24.90 2,000 49,800 2,000 Aug 16 09:15 PM Smith Brandon S. Chief Operating Officer Aug 16 '23 Option Exercise 11.12 4,000 44,480 4,000 Aug 16 09:15 PM Smith Brandon S. Chief Operating Officer Aug 16 '23 Sale 58.71 4,000 234,844 0 Aug 16 09:15 PM Garren Hideki Chief Medical Officer Aug 16 '23 Sale 58.74 2,000 117,480 0 Aug 16 09:15 PM Karp Carol D. Chief Regulatory Officer Aug 02 '23 Option Exercise 12.15 5,000 60,750 5,000 Aug 02 09:00 PM Zago Wagner M. Chief Scientific Officer Aug 02 '23 Option Exercise 12.15 4,000 48,600 4,000 Aug 02 09:00 PM Karp Carol D. Chief Regulatory Officer Aug 02 '23 Sale 67.01 5,000 335,072 0 Aug 02 09:00 PM Zago Wagner M. Chief Scientific Officer Aug 02 '23 Sale 67.05 4,000 268,182 0 Aug 02 09:00 PM Malecek Michael J Chief Legal Officer Jul 26 '23 Option Exercise 10.27 5,000 51,350 5,000 Jul 26 07:45 PM Malecek Michael J Chief Legal Officer Jul 26 '23 Sale 62.33 5,000 311,638 0 Jul 26 07:45 PM Walker Karin L Chief Accounting Officer Jul 19 '23 Option Exercise 15.04 5,000 75,200 5,000 Jul 19 08:50 PM Walker Karin L Chief Accounting Officer Jul 19 '23 Sale 69.19 5,000 345,943 0 Jul 19 08:50 PM Garren Hideki Chief Medical Officer Jul 12 '23 Option Exercise 24.90 2,000 49,800 2,000 Jul 12 08:45 PM Smith Brandon S. Chief Operating Officer Jul 12 '23 Option Exercise 11.12 4,000 44,480 4,000 Jul 12 08:45 PM Smith Brandon S. Chief Operating Officer Jul 12 '23 Sale 67.51 4,000 270,026 0 Jul 12 08:45 PM Garren Hideki Chief Medical Officer Jul 12 '23 Sale 67.51 2,000 135,027 0 Jul 12 08:45 PM Karp Carol D. Chief Regulatory Officer Jul 05 '23 Option Exercise 12.15 5,000 60,750 5,000 Jul 05 09:33 PM Zago Wagner M. Chief Scientific Officer Jul 05 '23 Option Exercise 12.15 4,000 48,600 4,000 Jul 05 09:32 PM Karp Carol D. Chief Regulatory Officer Jul 05 '23 Sale 68.13 5,000 340,636 0 Jul 05 09:33 PM Zago Wagner M. Chief Scientific Officer Jul 05 '23 Sale 68.16 4,000 272,648 0 Jul 05 09:32 PM Selkoe Dennis J. Director Jul 03 '23 Option Exercise 11.33 5,000 56,650 7,845 Jul 03 06:16 PM Selkoe Dennis J. Director Jul 03 '23 Sale 67.43 5,000 337,150 2,845 Jul 03 06:16 PM Malecek Michael J Chief Legal Officer Jun 28 '23 Option Exercise 10.27 5,000 51,350 5,000 Jun 28 08:45 PM Malecek Michael J Chief Legal Officer Jun 28 '23 Sale 69.82 5,000 349,118 0 Jun 28 08:45 PM Garren Hideki Chief Medical Officer Jun 16 '23 Option Exercise 24.90 7,331 182,542 7,331 Jun 16 07:31 PM Garren Hideki Chief Medical Officer Jun 16 '23 Sale 74.00 7,331 542,494 0 Jun 16 07:31 PM Garren Hideki Chief Medical Officer Jun 14 '23 Option Exercise 24.90 4,669 116,258 4,669 Jun 14 09:15 PM Smith Brandon S. Chief Operating Officer Jun 14 '23 Option Exercise 11.12 5,333 59,303 5,333 Jun 14 09:15 PM Smith Brandon S. Chief Operating Officer Jun 14 '23 Sale 73.98 5,333 394,562 0 Jun 14 09:15 PM Garren Hideki Chief Medical Officer Jun 14 '23 Sale 74.22 4,669 346,516 0 Jun 14 09:15 PM Zago Wagner M. Chief Scientific Officer Jun 07 '23 Option Exercise 26.09 19,000 495,750 19,000 Jun 07 09:49 PM Karp Carol D. Chief Regulatory Officer Jun 07 '23 Option Exercise 13.19 20,000 263,700 20,000 Jun 07 09:49 PM Karp Carol D. Chief Regulatory Officer Jun 07 '23 Sale 71.05 20,000 1,421,009 0 Jun 07 09:49 PM Zago Wagner M. Chief Scientific Officer Jun 07 '23 Sale 71.06 19,000 1,350,224 0 Jun 07 09:49 PM Malecek Michael J Chief Legal Officer May 31 '23 Option Exercise 10.27 5,000 51,350 5,000 May 31 09:30 PM Malecek Michael J Chief Legal Officer May 31 '23 Sale 64.64 5,000 323,223 0 May 31 09:30 PM Walker Karin L Chief Accounting Officer May 19 '23 Option Exercise 15.04 5,000 75,200 5,000 May 19 09:31 PM Walker Karin L Chief Accounting Officer May 19 '23 Sale 74.00 5,000 369,978 0 May 19 09:31 PM Nguyen Tran Chief Strategy Officer and CFO May 17 '23 Option Exercise 26.15 95,000 2,483,950 98,200 May 17 09:53 PM Kinney Gene G. President and CEO May 17 '23 Option Exercise 29.81 45,000 1,341,450 57,793 May 17 09:54 PM Nguyen Tran Chief Strategy Officer and CFO May 17 '23 Sale 73.99 95,000 7,028,921 3,200 May 17 09:53 PM Kinney Gene G. President and CEO May 17 '23 Sale 73.70 45,000 3,316,292 12,793 May 17 09:54 PM Selkoe Dennis J. Director May 03 '23 Option Exercise 18.07 15,000 271,110 17,845 May 05 09:30 PM Selkoe Dennis J. Director May 03 '23 Sale 57.00 15,000 855,000 2,845 May 05 09:30 PM
Index -
P/E -
EPS (ttm) -8.33
Insider Own 6.45%
Shs Outstand 82.31M
Perf Week -2.21%
Market Cap 3.57B
Forward P/E -
EPS next Y -4.99
Insider Trans -1.83%
Shs Float 77.02M
Perf Month -7.06%
Income -606.64M
PEG -
EPS next Q -1.73
Inst Own 104.18%
Short Float 5.69%
Perf Quarter -1.84%
Sales 434.25M
P/S 8.21
EPS this Y 22.64%
Inst Trans -3.16%
Short Ratio 6.28
Perf Half Y 30.89%
Book/sh 3.35
P/B 12.94
EPS next Y 21.85%
ROA -39.80%
Short Interest 4.38M
Perf Year -1.66%
Cash/sh 7.03
P/C 6.16
EPS next 5Y 8.90%
ROE -193.23%
52W Range 31.52 - 54.98
Perf YTD -9.45%
Dividend Est. -
P/FCF -
EPS past 5Y -15.75%
ROI -51.92%
52W High -21.24%
Beta 0.68
Dividend TTM -
Quick Ratio 2.49
Sales past 5Y 63.06%
Gross Margin 88.54%
52W Low 37.37%
ATR (14) 2.01
Dividend Ex-Date -
Current Ratio 2.61
EPS Y/Y TTM 17.65%
Oper. Margin -131.08%
RSI (14) 42.09
Volatility 3.38% 4.86%
Employees 1276
Debt/Eq 3.39
Sales Y/Y TTM 19.52%
Profit Margin -139.70%
Recom 1.29
Target Price 89.52
Option/Short Yes / Yes
LT Debt/Eq 3.24
EPS Q/Q 29.83%
Payout -
Rel Volume 2.27
Prev Close 42.54
Sales Surprise 6.71%
EPS Surprise 10.98%
Sales Q/Q 23.27%
Earnings May 02 AMC
Avg Volume 697.61K
Price 43.30
SMA20 -5.59%
SMA50 -9.07%
SMA200 2.81%
Trades
Volume 1,583,185
Change 1.79%
Date
Action
Analyst
Rating Change
Price Target Change
Apr-22-24 Initiated
RBC Capital Mkts
Outperform
$77
Dec-08-23 Initiated
Wells Fargo
Overweight
$72
Jun-14-23 Resumed
Credit Suisse
Outperform
$96
Jun-06-23 Upgrade
Evercore ISI
In-line → Outperform
$60 → $80
Apr-26-23 Initiated
Cantor Fitzgerald
Overweight
$114
Jan-18-23 Resumed
Canaccord Genuity
Buy
$90
Dec-30-22 Resumed
H.C. Wainwright
Buy
$82
Nov-03-22 Upgrade
Robert W. Baird
Neutral → Outperform
$50
Oct-13-22 Upgrade
Guggenheim
Neutral → Buy
$50
Aug-01-22 Downgrade
Evercore ISI
Outperform → In-line
$95 → $60
Mar-16-22 Upgrade
Credit Suisse
Neutral → Outperform
$99 → $105
Feb-11-22 Upgrade
JP Morgan
Neutral → Overweight
$132
Sep-30-21 Initiated
H.C. Wainwright
Buy
$106
Aug-19-21 Initiated
UBS
Sell
$73
Jul-15-21 Initiated
Guggenheim
Neutral
Jun-29-21 Upgrade
BofA Securities
Neutral → Buy
$162
Jun-04-21 Resumed
Robert W. Baird
Neutral
$109
May-06-21 Upgrade
Evercore ISI
In-line → Outperform
$144
May-06-21 Upgrade
Citigroup
Neutral → Buy
$160 → $151
Apr-26-21 Resumed
Credit Suisse
Neutral
$99
Show Previous Ratings
Apr-30-24 04:00PM
08:00AM
Apr-25-24 04:30PM
Apr-19-24 04:30PM
Apr-16-24 11:33AM
07:30AM
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Apr-15-24 07:30AM
07:00AM
Apr-12-24 04:22PM
08:00AM
Mar-22-24 04:00PM
Mar-20-24 08:11AM
Mar-12-24 05:00PM
Mar-11-24 03:00PM
Mar-08-24 09:38AM
Feb-27-24 04:30PM
04:05PM
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Feb-23-24 04:05PM
Feb-16-24 10:43AM
10:35AM
(Thomson Reuters StreetEvents)
07:53AM
Feb-15-24 04:15PM
(Associated Press Finance)
04:01PM
Feb-13-24 01:36PM
Feb-08-24 04:00PM
Feb-06-24 08:00AM
Feb-05-24 04:05PM
Jan-25-24 04:05PM
Jan-19-24 04:00PM
Jan-18-24 02:41PM
(Investor's Business Daily)
Jan-09-24 06:20PM
Jan-08-24 12:18PM
07:00AM
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07:00AM
Jan-07-24 11:00AM
Jan-04-24 08:12AM
08:00AM
Jan-03-24 08:00AM
Jan-02-24 04:05PM
Dec-27-23 06:41PM
Dec-21-23 05:21PM
(The Wall Street Journal)
04:30PM
Dec-18-23 09:29AM
08:00AM
Dec-15-23 10:18AM
Nov-20-23 04:30PM
Nov-17-23 04:30PM
Nov-07-23 05:00PM
Nov-04-23 01:12PM
12:16PM
Nov-03-23 11:43AM
Nov-02-23 06:26PM
04:36PM
(Associated Press Finance)
04:05PM
Oct-26-23 04:05PM
Oct-25-23 06:17AM
Oct-23-23 04:01PM
04:01PM
Oct-20-23 04:00PM
Oct-18-23 09:16PM
Oct-17-23 04:02PM
Oct-16-23 08:00AM
Oct-14-23 04:30PM
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Oct-09-23 08:00AM
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Sep-25-23 05:13PM
Sep-20-23 05:00PM
Sep-07-23 12:36PM
Aug-31-23 09:00AM
Aug-18-23 05:00PM
Aug-12-23 11:05AM
Aug-11-23 11:14AM
(American City Business Journals)
Aug-10-23 06:27PM
Aug-08-23 07:11AM
06:20AM
Aug-04-23 08:34AM
(Thomson Reuters StreetEvents) -8.79%
08:12AM
Aug-03-23 04:09PM
04:00PM
Jul-31-23 08:00AM
Jul-27-23 05:00PM
05:05AM
(American City Business Journals)
Jul-18-23 05:00PM
Jul-13-23 03:00PM
Jul-12-23 08:00AM
Jul-07-23 07:46AM
Jul-06-23 08:00AM
Jun-28-23 11:06AM
Jun-21-23 08:00AM
Jun-20-23 05:00PM
Jun-09-23 10:55AM
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03:21AM
Jun-05-23 04:00PM
May-24-23 06:39AM
May-19-23 08:30AM
May-18-23 05:00PM
11:15AM
May-17-23 08:00AM
May-15-23 02:43PM
(Investor's Business Daily)
May-08-23 04:02PM
May-05-23 04:01PM
Ultragenyx Pharmaceutical, Inc. engages in the identification, acquisition, development, and commercialization of novel products for the treatment of genetic diseases. Its products include Crysvita, Mepsevii, Dojolvi, and Evkeeza. The company was founded by Emil D. Kakkis in April 2010, and is headquartered in Novato, CA.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
Crombez Eric EVP and Chief Medical Officer Apr 18 '24 Sale 44.10 142 6,262 48,785 Apr 19 04:35 PM Kassberg Thomas Richard CBO & EVP Mar 11 '24 Sale 49.93 11,509 574,644 252,823 Mar 12 01:41 PM Fust Matthew K Director Mar 07 '24 Sale 50.88 12,195 620,443 14,860 Mar 11 12:54 PM Harris Erik EVP & Chief Commercial Officer Mar 01 '24 Sale 53.76 4,768 256,328 67,163 Mar 05 08:08 PM Pinion John Richard See Remarks Mar 01 '24 Sale 53.76 4,173 224,340 89,268 Mar 05 08:15 PM Parschauer Karah Herdman EVP and Chief Legal Officer Mar 01 '24 Sale 53.76 3,756 201,923 67,340 Mar 05 08:22 PM Crombez Eric EVP and Chief Medical Officer Mar 01 '24 Sale 53.76 1,238 66,555 48,927 Mar 05 08:10 PM Kassberg Thomas Richard CBO & EVP Mar 01 '24 Sale 53.76 1,011 54,351 264,332 Mar 05 08:19 PM Huizenga Theodore Alan SVP, Chief Accounting Officer Mar 01 '24 Sale 53.76 341 18,332 41,380 Mar 05 08:13 PM KAKKIS EMIL D President & CEO Feb 07 '24 Sale 45.00 30,000 1,350,000 539,770 Feb 08 03:49 PM Huizenga Theodore Alan SVP, Chief Accounting Officer Jan 02 '24 Option Exercise 21.00 3,000 63,000 27,892 Jan 02 04:06 PM KAKKIS EMIL D President & CEO Dec 29 '23 Sale 47.87 30,000 1,436,100 569,770 Jan 02 04:07 PM Kassberg Thomas Richard CBO & EVP Oct 23 '23 Option Exercise 6.86 39,878 273,563 286,738 Oct 24 05:22 PM Kassberg Thomas Richard CBO & EVP Oct 23 '23 Sale 32.78 39,878 1,307,201 246,860 Oct 24 05:22 PM KAKKIS EMIL D President & CEO Oct 19 '23 Option Exercise 6.86 47,853 328,272 647,029 Oct 23 05:14 PM KAKKIS EMIL D President & CEO Oct 19 '23 Sale 33.52 47,853 1,604,033 599,743 Oct 23 05:14 PM Huizenga Theodore Alan SVP, Chief Accounting Officer Sep 07 '23 Option Exercise 21.00 2,000 42,000 25,777 Sep 11 01:52 PM Huizenga Theodore Alan SVP, Chief Accounting Officer Sep 07 '23 Sale 40.80 2,163 88,249 23,614 Sep 11 01:52 PM Harris Erik EVP & Chief Commercial Officer Sep 05 '23 Sale 37.96 6,000 227,760 51,281 Sep 06 05:51 PM Huizenga Theodore Alan SVP, Chief Accounting Officer Sep 01 '23 Sale 37.15 970 36,032 23,777 Sep 06 05:50 PM Sanders Corazon (Corsee) D. Director Jun 30 '23 Sale 46.76 585 27,355 8,985 Jun 30 02:34 PM Harris Erik EVP & Chief Commercial Officer Jun 19 '23 Sale 48.20 305 14,701 57,281 Jun 21 06:17 PM Sanders Corazon (Corsee) D. Director Jun 08 '23 Sale 51.65 1,485 76,700 9,570 Jun 09 02:31 PM Pinion John Richard See Remarks May 18 '23 Sale 50.00 2,012 100,600 74,744 May 19 01:54 PM Huizenga Theodore Alan SVP, Chief Accounting Officer May 09 '23 Option Exercise 21.00 3,000 63,000 30,747 May 10 08:09 PM Parschauer Karah Herdman EVP and Chief Legal Officer May 04 '23 Sale 45.00 4,378 197,010 51,982 May 05 02:16 PM
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