Index RUT
P/E -
EPS (ttm) -1.51
Insider Own 4.15%
Shs Outstand 69.58M
Perf Week 4.99%
Market Cap 963.94M
Forward P/E -
EPS next Y -1.75
Insider Trans 38.21%
Shs Float 66.57M
Perf Month 0.80%
Income -113.67M
PEG -
EPS next Q -0.10
Inst Own 100.89%
Short Float 6.23%
Perf Quarter 2.81%
Sales 62.20M
P/S 15.50
EPS this Y 16.11%
Inst Trans 0.49%
Short Ratio 8.05
Perf Half Y 41.49%
Book/sh 5.23
P/B 2.65
EPS next Y -21.02%
ROA -21.79%
Short Interest 4.15M
Perf Year 32.32%
Cash/sh 4.28
P/C 3.24
EPS next 5Y -
ROE -28.73%
52W Range 7.97 - 17.70
Perf YTD -5.19%
Dividend Est. -
P/FCF -
EPS past 5Y -6.52%
ROI -29.58%
52W High -21.58%
Beta 1.09
Dividend TTM -
Quick Ratio 4.10
Sales past 5Y 341.20%
Gross Margin 82.55%
52W Low 74.15%
ATR (14) 0.84
Dividend Ex-Date -
Current Ratio 4.10
EPS Y/Y TTM -148.23%
Oper. Margin -194.58%
RSI (14) 48.04
Volatility 6.50% 6.17%
Employees 277
Debt/Eq 0.06
Sales Y/Y TTM -86.52%
Profit Margin -182.75%
Recom 1.50
Target Price 20.44
Option/Short Yes / Yes
LT Debt/Eq 0.05
EPS Q/Q 3.54%
Payout -
Rel Volume 0.63
Prev Close 13.99
Sales Surprise -10.62%
EPS Surprise 1.71%
Sales Q/Q -3.07%
Earnings Oct 31 AMC
Avg Volume 515.58K
Price 13.88
SMA20 -1.71%
SMA50 -3.82%
SMA200 21.28%
Trades
Volume 323,701
Change -0.79%
Date
Action
Analyst
Rating Change
Price Target Change
Dec-16-24 Upgrade
JP Morgan
Neutral → Overweight
$18
Nov-07-24 Upgrade
Leerink Partners
Market Perform → Outperform
$10 → $25
Nov-01-24 Downgrade
Wells Fargo
Overweight → Equal Weight
$12
Mar-21-23 Resumed
Wells Fargo
Overweight
$12
Jan-04-23 Reiterated
H.C. Wainwright
Neutral
$10 → $8
Dec-20-22 Upgrade
Jefferies
Hold → Buy
$7.70 → $11
Nov-01-22 Downgrade
H.C. Wainwright
Buy → Neutral
$40 → $8
Oct-21-22 Downgrade
SVB Leerink
Outperform → Mkt Perform
$8
Oct-04-22 Resumed
Wells Fargo
Overweight
$45 → $9
May-05-22 Upgrade
Guggenheim
Neutral → Buy
$14
Mar-15-22 Initiated
Evercore ISI
Outperform
$15
Dec-10-21 Upgrade
SVB Leerink
Mkt Perform → Outperform
Nov-17-21 Resumed
Guggenheim
Neutral
Oct-07-21 Initiated
Jefferies
Hold
$32
Mar-31-21 Initiated
Credit Suisse
Outperform
$55
Feb-25-21 Downgrade
SVB Leerink
Outperform → Mkt Perform
$41
Feb-08-21 Resumed
H.C. Wainwright
Buy
$57
Jan-25-21 Downgrade
Citigroup
Buy → Neutral
$50 → $53
Sep-29-20 Resumed
JP Morgan
Neutral
$48
Aug-06-20 Initiated
SVB Leerink
Outperform
$45
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(FierceBiotech.com) -6.46%
Mar-06-24 10:53PM
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Zymeworks, Inc. is a biopharmaceutical company, which engages in the discovery, development, and commercialization of novel, multifunctional biotherapeutics. Its product includes Zanidatamab, which is a novel bispecific antibody that targets two distinct domains of the human epidermal growth factor receptor 2 (HER2). Zanidatamab's unique binding properties result in multiple mechanisms of action that may enable it to address unmet need in patient populations with HER2-expressing cancers. The company was founded on September 8, 2003 and is headquartered in Middletown, DE.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
EcoR1 Capital, LLC Director Jan 13 '25 Buy 13.39 74,125 992,875 15,485,203 Jan 15 06:12 PM EcoR1 Capital, LLC Director Jan 14 '25 Buy 13.56 54,500 739,265 15,539,703 Jan 15 06:12 PM EcoR1 Capital, LLC Director Jan 15 '25 Buy 14.01 39,029 546,671 15,578,732 Jan 15 06:12 PM EcoR1 Capital, LLC Director Jan 10 '25 Buy 13.13 204,098 2,678,990 15,411,078 Jan 10 06:27 PM EcoR1 Capital, LLC Director Jan 08 '25 Buy 14.07 21,021 295,829 15,206,980 Jan 10 06:27 PM Moore Paul Andrew Chief Scientific Officer Jan 06 '25 Option Exercise 0.00 37,166 0 34,741 Jan 06 08:35 PM Moore Paul Andrew Chief Scientific Officer Jan 06 '25 Sale 14.92 21,200 316,391 14,741 Jan 06 08:35 PM Galbraith Kenneth Chair & CEO Jan 06 '25 Option Exercise 0.00 114,332 0 114,209 Jan 06 08:34 PM Galbraith Kenneth Chair & CEO Jan 06 '25 Sale 14.92 57,291 855,017 47,543 Jan 06 08:34 PM Smith Jeffrey T L EVP & Chief Medical Officer Jan 06 '25 Option Exercise 0.00 20,000 0 20,000 Jan 06 08:19 PM Smith Jeffrey T L EVP & Chief Medical Officer Jan 06 '25 Sale 14.92 11,110 165,807 8,890 Jan 06 08:19 PM Smith Jeffrey T L Officer Jan 06 '25 Proposed Sale 14.46 11,110 160,651 Jan 06 07:50 PM Moore Paul Andrew Officer Jan 06 '25 Proposed Sale 14.46 21,200 306,552 Jan 06 07:43 PM Galbraith, Kenneth Officer Jan 06 '25 Proposed Sale 14.46 57,291 828,428 Jan 06 07:37 PM EcoR1 Capital, LLC Director Jan 02 '25 Buy 14.78 157,880 2,333,403 15,185,959 Jan 02 05:51 PM EcoR1 Capital, LLC Director Dec 31 '24 Buy 14.57 146,501 2,134,446 15,028,079 Jan 02 05:51 PM EcoR1 Capital, LLC Director Dec 30 '24 Buy 14.47 58,988 853,326 14,881,578 Jan 02 05:51 PM EcoR1 Capital, LLC Director Dec 27 '24 Buy 14.49 101,659 1,473,181 14,822,590 Dec 27 06:41 PM EcoR1 Capital, LLC Director Dec 26 '24 Buy 14.38 16,692 240,038 14,720,931 Dec 27 06:41 PM EcoR1 Capital, LLC Director Dec 24 '24 Buy 14.12 11,958 168,896 14,704,239 Dec 27 06:41 PM
Index RUT
P/E -
EPS (ttm) -6.07
Insider Own 14.73%
Shs Outstand 30.43M
Perf Week 11.54%
Market Cap 482.29M
Forward P/E -
EPS next Y -5.36
Insider Trans 7.61%
Shs Float 25.95M
Perf Month -4.80%
Income -165.66M
PEG -
EPS next Q -1.62
Inst Own 103.48%
Short Float 28.23%
Perf Quarter -54.31%
Sales 57.17M
P/S 8.44
EPS this Y -0.07%
Inst Trans 31.75%
Short Ratio 11.31
Perf Half Y -53.99%
Book/sh 2.77
P/B 5.72
EPS next Y 11.84%
ROA -33.78%
Short Interest 7.33M
Perf Year -31.86%
Cash/sh 14.14
P/C 1.12
EPS next 5Y -
ROE -161.81%
52W Range 12.51 - 41.31
Perf YTD 19.71%
Dividend Est. -
P/FCF -
EPS past 5Y -19.45%
ROI -36.85%
52W High -61.63%
Beta -0.03
Dividend TTM -
Quick Ratio 10.23
Sales past 5Y 201.20%
Gross Margin 95.80%
52W Low 26.70%
ATR (14) 1.30
Dividend Ex-Date -
Current Ratio 10.23
EPS Y/Y TTM -12.12%
Oper. Margin -245.01%
RSI (14) 48.17
Volatility 7.02% 7.26%
Employees 117
Debt/Eq 4.35
Sales Y/Y TTM 282.17%
Profit Margin -289.75%
Recom 1.55
Target Price 33.90
Option/Short Yes / Yes
LT Debt/Eq 4.33
EPS Q/Q 19.10%
Payout -
Rel Volume 1.25
Prev Close 15.03
Sales Surprise 265.83%
EPS Surprise 30.78%
Sales Q/Q 804.67%
Earnings Nov 05 AMC
Avg Volume 648.00K
Price 15.85
SMA20 9.87%
SMA50 -14.13%
SMA200 -40.46%
Trades
Volume 813,194
Change 5.46%
Date
Action
Analyst
Rating Change
Price Target Change
Dec-11-24 Downgrade
H.C. Wainwright
Buy → Neutral
$52 → $19
Dec-02-24 Downgrade
BTIG Research
Buy → Neutral
Jul-22-24 Initiated
H.C. Wainwright
Buy
$55
Jul-19-24 Upgrade
JP Morgan
Neutral → Overweight
$29 → $69
Apr-16-24 Initiated
Leerink Partners
Outperform
$47
Apr-11-24 Initiated
Wells Fargo
Overweight
$56
Mar-12-24 Upgrade
Wedbush
Neutral → Outperform
$20 → $34
Feb-26-24 Initiated
BTIG Research
Buy
$55
Feb-21-24 Initiated
Stifel
Buy
$50
Feb-16-24 Initiated
Piper Sandler
Overweight
$80
May-22-23 Upgrade
JP Morgan
Underweight → Neutral
$31 → $30
May-18-23 Initiated
TD Cowen
Outperform
Jan-06-23 Downgrade
Raymond James
Outperform → Mkt Perform
Nov-01-22 Upgrade
Guggenheim
Neutral → Buy
$44
Sep-19-22 Resumed
H.C. Wainwright
Buy
$35
Sep-13-22 Downgrade
Truist
Buy → Hold
$50 → $28
Sep-01-22 Initiated
Raymond James
Outperform
$35
Mar-22-22 Downgrade
Guggenheim
Buy → Neutral
Jun-22-21 Initiated
H.C. Wainwright
Buy
$43
May-21-21 Initiated
UBS
Neutral
$29
Show Previous Ratings
Jan-13-25 09:42AM
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(Investor's Business Daily)
-6.35%
10:05AM
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AnaptysBio, Inc. is a clinical stage biotechnology company. engages in the development of antibody product candidates. Its products pipeline include ANB030, ANB030, and Imsidolimab. It also offers SHM platform that replicate the natural process of somatic hypermutation embedded within the human immune system to rapidly develop a diverse range of therapeutic-grade antibodies in vitro. The company was founded by Andrew B. Cubitt, William J. Boyle, Kevin J. Kinsella, and Nicholas B. Lydon in November 2005 and is headquartered in San Diego, CA.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
Schmid John P. Director Jan 13 '25 Option Exercise 6.50 42,337 275,007 46,237 Jan 15 05:04 PM EcoR1 Capital, LLC Director Dec 30 '24 Buy 12.92 65,184 842,060 7,860,180 Jan 02 06:17 PM EcoR1 Capital, LLC Director Dec 31 '24 Buy 12.93 13,268 171,513 7,873,448 Jan 02 06:17 PM EcoR1 Capital, LLC Director Jan 02 '25 Buy 12.95 6,646 86,070 7,880,094 Jan 02 06:17 PM RENTON HOLLINGS Director Nov 29 '24 Option Exercise 6.93 10,000 69,300 11,950 Dec 03 04:35 PM RENTON HOLLINGS Director Nov 29 '24 Sale 25.00 10,000 250,000 1,950 Dec 03 04:35 PM HOLLINGS C RENTON Director Nov 29 '24 Proposed Sale 25.00 10,000 250,000 Nov 29 01:29 PM Lizzul Paul F. Chief Medical Officer Sep 23 '24 Option Exercise 18.50 1,500 27,750 16,898 Sep 24 04:18 PM Lizzul Paul F. Chief Medical Officer Sep 23 '24 Sale 38.67 1,500 58,005 15,398 Sep 24 04:18 PM PAUL F LIZZUL Officer Sep 23 '24 Proposed Sale 38.67 1,500 58,005 Sep 23 04:16 PM Orwin John A Director Sep 15 '24 Option Exercise 0.00 1,300 0 3,335 Sep 17 06:45 PM LOUMEAU ERIC J CHIEF LEGAL OFFICER Sep 16 '24 Option Exercise 14.02 5,000 70,100 13,520 Sep 17 06:44 PM LOUMEAU ERIC J CHIEF LEGAL OFFICER Sep 14 '24 Option Exercise 0.00 6,000 0 10,740 Sep 17 06:44 PM LOUMEAU ERIC J CHIEF LEGAL OFFICER Sep 16 '24 Sale 39.82 8,720 347,270 7,020 Sep 17 06:44 PM LOUMEAU ERIC J CHIEF LEGAL OFFICER Sep 17 '24 Sale 38.41 3,780 145,191 3,240 Sep 17 06:44 PM Lizzul Paul F. Chief Medical Officer Sep 16 '24 Sale 38.93 2,220 86,425 15,398 Sep 17 06:42 PM MULROY DENNIS CHIEF FINANCIAL OFFICER Sep 16 '24 Option Exercise 20.16 10,000 201,600 14,744 Sep 17 06:41 PM MULROY DENNIS CHIEF FINANCIAL OFFICER Sep 16 '24 Sale 39.91 12,220 487,725 4,744 Sep 17 06:41 PM ERIC J LOUMEAU Officer Sep 17 '24 Proposed Sale 38.41 3,780 145,191 Sep 17 04:02 PM DENNIS MULROY Officer Sep 16 '24 Proposed Sale 40.13 10,000 401,300 Sep 16 04:33 PM ERIC J LOUMEAU Officer Sep 16 '24 Proposed Sale 40.13 6,500 260,845 Sep 16 04:22 PM Lizzul Paul F. Chief Medical Officer Aug 14 '24 Option Exercise 18.50 2,000 37,000 13,618 Aug 16 04:09 PM Lizzul Paul F. Chief Medical Officer Aug 14 '24 Sale 40.00 2,000 80,000 11,618 Aug 16 04:09 PM EcoR1 Capital, LLC 10% Owner Aug 14 '24 Buy 36.50 273,972 9,999,978 7,794,996 Aug 16 12:04 PM PAUL F LIZZUL Officer Aug 14 '24 Proposed Sale 40.00 2,000 80,000 Aug 14 04:34 PM Lizzul Paul F. Chief Medical Officer Jul 18 '24 Option Exercise 18.50 1,500 27,750 13,118 Jul 19 08:35 PM Lizzul Paul F. Chief Medical Officer Jul 18 '24 Sale 35.00 1,500 52,500 11,618 Jul 19 08:35 PM RENTON HOLLINGS Director Jul 15 '24 Option Exercise 6.93 10,000 69,300 11,950 Jul 17 04:45 PM RENTON HOLLINGS Director Jul 15 '24 Sale 30.64 10,000 306,422 1,950 Jul 17 04:45 PM FENTON DENNIS M Director Jun 21 '24 Sale 23.17 1,950 45,182 1,950 Jun 24 05:23 PM FENTON DENNIS M Director Jun 15 '24 Option Exercise 0.00 3,900 0 3,900 Jun 18 08:18 PM Marquet Magda Director Jun 15 '24 Option Exercise 0.00 3,900 0 3,900 Jun 18 08:17 PM Schmid John P. Director Jun 15 '24 Option Exercise 0.00 3,900 0 3,900 Jun 18 08:17 PM Ware J. Anthony Director Jun 15 '24 Option Exercise 0.00 3,900 0 7,500 Jun 18 08:16 PM Orwin John A Director Jun 15 '24 Option Exercise 0.00 2,035 0 2,035 Jun 18 08:15 PM RENTON HOLLINGS Director Jun 15 '24 Option Exercise 0.00 3,900 0 3,900 Jun 18 08:15 PM RENTON HOLLINGS Director Jun 18 '24 Sale 23.16 1,950 45,162 1,950 Jun 18 08:15 PM Jain Rita Director Jun 15 '24 Option Exercise 0.00 4,534 0 4,534 Jun 18 08:14 PM MULROY DENNIS CHIEF FINANCIAL OFFICER May 22 '24 Sale 23.72 1,500 35,580 964 May 24 04:12 PM Faga Daniel CEO Mar 22 '24 Sale 22.78 145,940 3,325,185 752,087 Mar 26 08:10 PM Faga Daniel CEO Mar 25 '24 Sale 21.42 3,000 64,268 749,087 Mar 26 08:10 PM LOUMEAU ERIC J CHIEF LEGAL OFFICER Feb 16 '24 Option Exercise 14.02 5,000 70,100 8,240 Feb 21 05:38 PM LOUMEAU ERIC J CHIEF LEGAL OFFICER Feb 16 '24 Sale 25.00 5,000 125,000 3,240 Feb 21 05:38 PM MULROY DENNIS CHIEF FINANCIAL OFFICER Jan 30 '24 Sale 23.63 3,065 72,425 964 Feb 01 05:27 PM
Index RUT
P/E -
EPS (ttm) -1.17
Insider Own 53.59%
Shs Outstand 107.41M
Perf Week -2.56%
Market Cap 306.14M
Forward P/E -
EPS next Y -1.43
Insider Trans -14.31%
Shs Float 49.85M
Perf Month -3.39%
Income -123.39M
PEG -
EPS next Q -0.34
Inst Own 48.08%
Short Float 15.03%
Perf Quarter -60.08%
Sales 43.38M
P/S 7.06
EPS this Y -11.20%
Inst Trans 8.24%
Short Ratio 3.79
Perf Half Y -70.95%
Book/sh 2.13
P/B 1.34
EPS next Y -18.65%
ROA -31.62%
Short Interest 7.49M
Perf Year -75.15%
Cash/sh 2.73
P/C 1.04
EPS next 5Y -
ROE -48.80%
52W Range 2.59 - 13.01
Perf YTD -7.77%
Dividend Est. -
P/FCF -
EPS past 5Y -
ROI -46.75%
52W High -78.09%
Beta 0.81
Dividend TTM -
Quick Ratio 8.00
Sales past 5Y 132.62%
Gross Margin 94.25%
52W Low 10.25%
ATR (14) 0.28
Dividend Ex-Date -
Current Ratio 8.00
EPS Y/Y TTM -5.39%
Oper. Margin -322.00%
RSI (14) 41.79
Volatility 7.68% 8.98%
Employees 140
Debt/Eq 0.16
Sales Y/Y TTM 15.67%
Profit Margin -284.43%
Recom 1.11
Target Price 11.50
Option/Short Yes / Yes
LT Debt/Eq 0.15
EPS Q/Q -17.18%
Payout -
Rel Volume 0.39
Prev Close 2.78
Sales Surprise 43.90%
EPS Surprise 26.37%
Sales Q/Q 8.15%
Earnings Nov 06 BMO
Avg Volume 1.98M
Price 2.85
SMA20 -5.54%
SMA50 -14.51%
SMA200 -59.64%
Trades
Volume 772,040
Change 2.52%
Date
Action
Analyst
Rating Change
Price Target Change
Jul-17-24 Initiated
Jefferies
Buy
$19
Apr-04-24 Initiated
Cantor Fitzgerald
Overweight
Feb-12-24 Initiated
Piper Sandler
Overweight
$18
Dec-08-23 Initiated
B. Riley Securities
Buy
$16
Oct-20-22 Upgrade
H.C. Wainwright
Neutral → Buy
$10
Sep-20-21 Initiated
SVB Leerink
Outperform
$25
Dec-03-24 07:00AM
Nov-27-24 07:00AM
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Tango Therapeutics, Inc. is a clinical-stage biotechnology company, which engages in discovering and delivering precision cancer medicines. It also identifies novel targets and develops new drugs directed at tumor suppressor gene loss in defined patient populations with high unmet medical need. The company was founded by Alan Ashworth, William G. Kaelin, Jr., Jose Baselga, and Antoni Ribas in 2017 and is headquartered in Boston, MA.
Insider Trading
Relationship
Date
Transaction
Cost
#Shares
Value ($)
#Shares Total
SEC Form 4
Rothenberg Mace Director Nov 18 '24 Buy 3.78 10,000 37,800 31,250 Nov 18 07:20 PM Rothenberg Mace Director Nov 14 '24 Buy 3.62 10,000 36,200 21,250 Nov 18 07:20 PM EcoR1 Capital, LLC 10% Owner Nov 06 '24 Sale 3.28 1,494,558 4,896,023 11,836,178 Nov 08 07:24 PM EcoR1 Capital, LLC 10% Owner Nov 07 '24 Sale 2.94 1,205,442 3,539,720 10,630,736 Nov 08 07:24 PM Boxer Capital Management, LLC Nov 06 '24 Sale 3.14 3,080,000 9,671,200 3,610,642 Nov 07 09:30 PM Boxer Capital Management, LLC Member of group formerly ownin Nov 06 '24 Proposed Sale 5.18 575,000 2,978,500 Nov 06 09:40 PM Boxer Capital Management, LLC Oct 25 '24 Sale 6.87 633,000 4,348,710 6,690,642 Oct 28 06:59 AM Boxer Capital Management, LLC Member of group owning over 10 Oct 25 '24 Proposed Sale 6.29 100,000 629,000 Oct 25 09:30 PM Boxer Capital Management, LLC Oct 21 '24 Sale 7.05 625,000 4,406,250 7,573,642 Oct 23 09:31 PM Boxer Capital Management, LLC Oct 22 '24 Sale 6.78 250,000 1,695,000 7,323,642 Oct 23 09:31 PM Boxer Capital Management, LLC Member of group owning over 10 Oct 22 '24 Proposed Sale 7.15 127,600 912,340 Oct 22 08:50 PM Boxer Capital Management, LLC Member of group owning over 10 Oct 21 '24 Proposed Sale 7.46 500,000 3,730,000 Oct 22 12:03 PM Third Rock Ventures IV, L.P. 10% Owner Sep 13 '24 Sale 10.53 67,400 709,756 16,859,075 Sep 17 04:48 PM Third Rock Ventures IV, L.P. Affiliate Sep 13 '24 Proposed Sale 10.50 67,400 707,700 Sep 13 05:43 PM Third Rock Ventures IV, L.P. 10% Owner Sep 05 '24 Sale 11.56 75,000 867,135 16,926,475 Sep 09 07:19 PM Third Rock Ventures IV, L.P. Affiliate Sep 05 '24 Proposed Sale 11.68 75,000 876,000 Sep 05 05:01 PM Third Rock Ventures IV, L.P. 10% Owner Aug 30 '24 Sale 11.60 175,000 2,029,702 17,001,475 Sep 04 08:42 PM Third Rock Ventures IV, L.P. Affiliate Aug 30 '24 Proposed Sale 11.83 175,000 2,070,250 Aug 30 05:24 PM Third Rock Ventures IV, L.P. 10% Owner Aug 27 '24 Sale 11.55 25,000 288,665 17,176,475 Aug 29 04:40 PM Third Rock Ventures IV, L.P. Affiliate Aug 27 '24 Proposed Sale 11.40 25,000 285,000 Aug 27 04:53 PM Third Rock Ventures IV, L.P. 10% Owner Aug 19 '24 Sale 10.09 150,000 1,513,920 17,201,475 Aug 20 05:59 PM Third Rock Ventures IV, L.P. 10% Owner Aug 16 '24 Sale 9.79 135,000 1,321,448 17,351,475 Aug 20 05:59 PM Third Rock Ventures IV, L.P. Affiliate Aug 19 '24 Proposed Sale 10.68 150,000 1,602,000 Aug 19 05:35 PM Third Rock Ventures IV, L.P. Affiliate Aug 16 '24 Proposed Sale 9.96 135,000 1,344,600 Aug 16 05:14 PM Third Rock Ventures IV, L.P. 10% Owner Jul 31 '24 Sale 9.93 100,000 993,380 17,526,475 Aug 01 05:51 PM Third Rock Ventures IV, L.P. 10% Owner Jul 30 '24 Sale 9.80 95,000 931,114 17,626,475 Aug 01 05:51 PM Third Rock Ventures IV, L.P. 10% Owner Aug 01 '24 Sale 9.80 40,000 392,000 17,486,475 Aug 01 05:51 PM Third Rock Ventures IV, L.P. Affiliate Aug 01 '24 Proposed Sale 9.45 40,000 378,000 Aug 01 05:30 PM Third Rock Ventures IV, L.P. Affiliate Jul 31 '24 Proposed Sale 9.85 100,000 985,000 Jul 31 05:32 PM Third Rock Ventures IV, L.P. Affiliate Jul 30 '24 Proposed Sale 9.70 95,000 921,500 Jul 30 05:15 PM Third Rock Ventures IV, L.P. 10% Owner Jul 26 '24 Sale 9.84 50,000 491,950 17,721,475 Jul 30 04:15 PM Third Rock Ventures IV, L.P. Affiliate Jul 26 '24 Proposed Sale 9.75 50,000 487,500 Jul 26 05:41 PM Third Rock Ventures IV, L.P. 10% Owner Jul 24 '24 Sale 9.82 200,000 1,963,160 17,872,074 Jul 26 04:15 PM Third Rock Ventures IV, L.P. 10% Owner Jul 25 '24 Sale 9.87 100,599 992,771 17,771,475 Jul 26 04:15 PM Third Rock Ventures IV, L.P. 10% Owner Jul 22 '24 Sale 9.78 262,740 2,570,096 18,197,074 Jul 24 04:15 PM Third Rock Ventures IV, L.P. 10% Owner Jul 23 '24 Sale 9.79 125,000 1,223,350 18,072,074 Jul 24 04:15 PM Third Rock Ventures IV, L.P. 10% Owner Jul 18 '24 Sale 9.81 191,490 1,878,479 18,459,814 Jul 22 04:15 PM Third Rock Ventures IV, L.P. 10% Owner Jul 17 '24 Sale 9.79 550,171 5,386,339 18,651,304 Jul 18 04:15 PM MVA Investors, LLC Jul 01 '24 Sale 8.87 110,731 982,184 203,793 Jul 02 08:56 PM MVA Investors, LLC Jul 02 '24 Sale 8.68 95,000 824,600 108,793 Jul 02 08:56 PM MVA Investors, LLC Jun 28 '24 Sale 8.57 29,000 248,530 314,524 Jul 02 08:56 PM MVA Investors, LLC Jun 07 '24 Sale 6.88 77,000 529,760 343,524 Jun 07 09:14 PM MVA Investors, LLC Jun 06 '24 Sale 7.24 63,000 456,120 420,524 Jun 07 09:14 PM MVA Investors, LLC May 02 '24 Sale 7.56 75,000 567,000 543,524 May 03 09:34 PM MVA Investors, LLC May 01 '24 Sale 7.43 75,000 557,250 618,524 May 03 09:34 PM MVA Investors, LLC May 03 '24 Sale 7.61 60,000 456,600 483,524 May 03 09:34 PM Third Rock Ventures IV, L.P. 10% Owner Feb 20 '24 Sale 12.00 162,500 1,950,000 19,201,475 Feb 21 05:52 PM Weber Barbara Chief Executive Officer Feb 06 '24 Sale 12.56 4,681 58,806 1,539,624 Feb 08 09:14 PM Weber Barbara Chief Executive Officer Feb 07 '24 Sale 12.62 4,457 56,246 1,535,167 Feb 08 09:14 PM Barry Douglas General Counsel Feb 06 '24 Sale 12.56 1,422 17,864 45,335 Feb 08 09:09 PM Barry Douglas General Counsel Feb 07 '24 Sale 12.62 1,354 17,087 43,981 Feb 08 09:09 PM Beckman Daniella Chief Financial Officer Feb 06 '24 Sale 12.56 1,908 23,969 134,214 Feb 08 09:08 PM Beckman Daniella Chief Financial Officer Feb 07 '24 Sale 12.62 1,817 22,930 132,397 Feb 08 09:08 PM Crystal Adam See Remarks Feb 06 '24 Sale 12.56 4,288 53,868 123,561 Feb 08 09:04 PM Crystal Adam See Remarks Feb 07 '24 Sale 12.62 4,083 51,527 119,478 Feb 08 09:04 PM
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